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Motif ID: SMAD1..7,9.p2

Z-value: 1.713

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr8_+_32623792	3.258	NM_013959	NRG1	neuregulin 1
chr19_+_40299058	3.215		FXYD3	FXYD domain containing ion transport regulator 3
chr1_+_181422016	2.715		LAMC2	laminin, gamma 2
chr11_+_66580884	2.673		RHOD	ras homolog gene family, member D
chr15_-_81744469	2.610	NM_001717	BNC1	basonuclin 1
chr5_-_151046680	2.456	NM_003118	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chrX_-_37916138	2.360		SRPX	sushi-repeat containing protein, X-linked
chr2_-_110231431	2.150	NM_005434	MALL	mal, T-cell differentiation protein-like
chrX_+_153767803	2.115	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr5_-_151046638	2.109		SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chrX_-_154341451	2.095	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr20_-_14266200	2.045	NM_013281 NM_198391	FLRT3	fibronectin leucine rich transmembrane protein 3
chr12_-_45759691	1.964	NM_001143668 NM_181847	AMIGO2	adhesion molecule with Ig-like domain 2
chr1_+_181421796	1.701	NM_005562 NM_018891	LAMC2	laminin, gamma 2
chr1_+_181421984	1.643		LAMC2	laminin, gamma 2
chr11_-_124871258	1.636	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr6_+_107066422	1.616	NM_001624	AIM1	absent in melanoma 1
chr19_-_48976852	1.560		KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr2_+_71148915	1.553	NM_017567	NAGK	N-acetylglucosamine kinase
chr11_+_66580861	1.530	NM_014578	RHOD	ras homolog gene family, member D
chr21_+_38550533	1.521	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr12_-_51200347	1.518	NM_000424	KRT5	keratin 5
chr16_+_69060325	1.508		FUK	fucokinase
chr21_+_38550739	1.458	NM_170736	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr15_+_99237555	1.422		ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr12_-_51153788	1.413	NM_173086	KRT6C	keratin 6C
chr15_+_99237527	1.383	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr17_+_67628749	1.357	NM_000346	SOX9	SRY (sex determining region Y)-box 9
chr19_+_43446937	1.338	NM_001166103 NM_021102	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr1_-_27871306	1.314	NM_002038 NM_022872 NM_022873	IFI6	interferon, alpha-inducible protein 6
chr10_+_8136778	1.310		GATA3	GATA binding protein 3
chr9_-_98841186	1.295	NM_001333	CTSL2	cathepsin L2
chr20_+_43875078	1.287	NM_181801	UBE2C	ubiquitin-conjugating enzyme E2C
chr1_-_27871287	1.272		IFI6	interferon, alpha-inducible protein 6
chr10_-_91001496	1.261		LIPA	lipase A, lysosomal acid, cholesterol esterase
chr16_+_56219802	1.250	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr1_-_151804929	1.233	NM_005978	S100A2	S100 calcium binding protein A2
chr1_-_6368324	1.232	NM_181864	ACOT7	acyl-CoA thioesterase 7
chr2_-_110230927	1.226		MALL	mal, T-cell differentiation protein-like
chr10_-_91001531	1.211		LIPA	lipase A, lysosomal acid, cholesterol esterase
chr10_-_91001542	1.202		LIPA	lipase A, lysosomal acid, cholesterol esterase
chr17_-_72093529	1.200		ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr10_-_91001566	1.192	NM_000235 NM_001127605	LIPA	lipase A, lysosomal acid, cholesterol esterase
chr17_-_72093739	1.190	NM_006456	ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr2_+_101981888	1.186	NM_173343	IL1R2	interleukin 1 receptor, type II
chr10_-_98021144	1.184	NM_001114094 NM_013314	BLNK	B-cell linker
chr7_+_134114957	1.181		CALD1	caldesmon 1
chr17_-_7238546	1.179	NM_020360	PLSCR3	phospholipid scramblase 3
chr1_-_150276091	1.166		S100A11	S100 calcium binding protein A11
chr15_+_38923470	1.162	NM_003710 NM_181642	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr1_-_150276064	1.151		S100A11	S100 calcium binding protein A11
chr19_-_48977247	1.124	NM_002250	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr9_-_21965131	1.105	NM_000077 NM_001195132	CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr2_+_71149193	1.102		NAGK	N-acetylglucosamine kinase
chr1_+_27062215	1.100	NM_006142	SFN	stratifin
chr18_+_19706979	1.097	NM_000227 NM_001127718	LAMA3	laminin, alpha 3
chr5_+_17270474	1.093	NM_006317	BASP1	brain abundant, membrane attached signal protein 1
chr17_-_72093476	1.086		ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr14_-_105163301	1.065		IGHG4	immunoglobulin heavy constant gamma 4 (G4m marker)
chr19_-_11550576	1.045	NM_001111034	ACP5	acid phosphatase 5, tartrate resistant
chrX_+_151837064	1.023	NM_001178113	ZNF185	zinc finger protein 185 (LIM domain)
chr2_+_71148936	1.022		NAGK	N-acetylglucosamine kinase
chr11_+_9642226	0.997		SWAP70	SWAP switching B-cell complex 70kDa subunit
chr1_-_181826633	0.984	NM_001127651	NCF2	neutrophil cytosolic factor 2
chr9_-_109291130	0.983		KLF4	Kruppel-like factor 4 (gut)
chr5_+_17270781	0.977		BASP1	brain abundant, membrane attached signal protein 1
chr15_+_38923914	0.969	NM_001032367	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr13_-_39075304	0.968		LHFP	lipoma HMGIC fusion partner
chr15_-_50608296	0.967	NM_000259 NM_001142495	MYO5A	myosin VA (heavy chain 12, myoxin)
chr6_-_32929570	0.944		TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr16_+_80370426	0.936	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chrX_+_48915127	0.931	NM_002668	PLP2	proteolipid protein 2 (colonic epithelium-enriched)
chrX_-_62891667	0.927		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr6_-_138470160	0.925	NM_022121	PERP	PERP, TP53 apoptosis effector
chr1_+_36409277	0.923		MAP7D1	MAP7 domain containing 1
chr3_-_45162901	0.923	NM_022842 NM_178181	CDCP1	CUB domain containing protein 1
chr5_+_49998677	0.920		PARP8	poly (ADP-ribose) polymerase family, member 8
chr19_+_45973139	0.917	NM_006533	MIA	melanoma inhibitory activity
chr17_-_37034288	0.916	NM_000422	KRT17	keratin 17
chr3_-_151171190	0.902	NM_002628 NM_053024	PFN2	profilin 2
chr3_-_45162847	0.898		CDCP1	CUB domain containing protein 1
chr7_-_41709191	0.897	NM_002192	INHBA	inhibin, beta A
chr14_-_106249999	0.892		IGHA1	immunoglobulin heavy constant alpha 1
chr8_-_134378630	0.885	NM_001135242 NM_006096	NDRG1	N-myc downstream regulated 1
chr9_-_109291575	0.884		KLF4	Kruppel-like factor 4 (gut)
chr22_+_36365629	0.873	NM_018957	SH3BP1	SH3-domain binding protein 1
chr8_-_143864933	0.871	NM_003695	LY6D	lymphocyte antigen 6 complex, locus D
chr14_-_105182025	0.862
chr19_-_56221681	0.860	NM_001136032	KLK11	kallikrein-related peptidase 11
chr14_+_63750611	0.839	NM_182913	SYNE2	spectrin repeat containing, nuclear envelope 2
chr4_-_102487356	0.837		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr9_+_33614214	0.833		ANXA2P2	annexin A2 pseudogene 2
chr9_-_32516164	0.820	NM_014314	DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chrX_+_102727068	0.807	NM_001006935 NM_001006937 NM_024863	TCEAL4	transcription elongation factor A (SII)-like 4
chr14_-_105181939	0.803		IGHG2	immunoglobulin heavy constant gamma 2 (G2m marker)
chr3_-_16530132	0.802	NM_015150	RFTN1	raftlin, lipid raft linker 1
chr1_-_93919789	0.802	NM_003567	BCAR3	breast cancer anti-estrogen resistance 3
chr10_+_8136639	0.801	NM_001002295 NM_002051	GATA3	GATA binding protein 3
chr3_-_126412882	0.796	NM_001195483	SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chr12_+_64504408	0.793	NM_003483 NM_003484	HMGA2	high mobility group AT-hook 2
chr17_-_1342700	0.790	NM_001080779	MYO1C	myosin IC
chr11_-_117640166	0.780		MPZL2	myelin protein zero-like 2
chr17_+_23686674	0.779	NM_021137	TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr7_+_134114701	0.777	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr17_-_7248137	0.777	NM_152766	C17orf61-PLSCR3 C17orf61	C17orf61-PLSCR3 read-through transcript chromosome 17 open reading frame 61
chr16_+_22732982	0.766		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr10_+_88718167	0.759	NM_006829	C10orf116	chromosome 10 open reading frame 116
chr14_-_105182159	0.758		IGHG2	immunoglobulin heavy constant gamma 2 (G2m marker)
chr14_-_23107106	0.758	NM_003917	AP1G2	adaptor-related protein complex 1, gamma 2 subunit
chr22_+_21559959	0.756	NM_001178126	IGLL5 IGLC1	immunoglobulin lambda-like polypeptide 5 immunoglobulin lambda constant 1 (Mcg marker)
chr12_-_51253875	0.749	NM_175053	KRT74	keratin 74
chr11_-_117640407	0.747	NM_005797 NM_144765	MPZL2	myelin protein zero-like 2
chr3_-_129024665	0.745	NM_001003794	MGLL	monoglyceride lipase
chr6_+_107067019	0.744		AIM1	absent in melanoma 1
chr11_-_57091656	0.741	NM_004223	UBE2L6	ubiquitin-conjugating enzyme E2L 6
chr19_-_11550765	0.740	NM_001111035 NM_001111036	ACP5	acid phosphatase 5, tartrate resistant
chrX_-_106846684	0.737		TSC22D3	TSC22 domain family, member 3
chr1_+_44171578	0.726	NM_001136215 NM_057090 NM_057091	ARTN	artemin
chr8_+_104380234	0.725	NM_001164616 NM_003506	FZD6	frizzled homolog 6 (Drosophila)
chr6_-_128883125	0.721	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr12_-_105165805	0.718	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr1_-_27871245	0.718		IFI6	interferon, alpha-inducible protein 6
chr17_+_71229151	0.717		ITGB4	integrin, beta 4
chr2_-_56004366	0.715	NM_001039348 NM_001039349	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1
chrX_-_62891730	0.714	NM_001173480 NM_015185	ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr1_-_150276114	0.708	NM_005620	S100A11	S100 calcium binding protein A11
chr9_-_139010805	0.700	NM_004669	CLIC3	chloride intracellular channel 3
chr17_+_71229191	0.699		ITGB4	integrin, beta 4
chr16_+_67328693	0.699	NM_004360	CDH1	cadherin 1, type 1, E-cadherin (epithelial)
chr22_-_43986896	0.698		KIAA0930	KIAA0930
chr1_-_43691932	0.694		HYI	hydroxypyruvate isomerase (putative)
chr16_+_80370400	0.685		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr10_+_8137356	0.678		GATA3	GATA binding protein 3
chr19_-_1989937	0.677		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr6_-_112033752	0.669		TRAF3IP2	TRAF3 interacting protein 2
chr2_-_162883062	0.667	NM_022168	IFIH1	interferon induced with helicase C domain 1
chr10_-_116382089	0.662		ABLIM1	actin binding LIM protein 1
chr11_-_117640196	0.659		MPZL2	myelin protein zero-like 2
chrX_-_62891066	0.644		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr5_-_57791544	0.643	NM_006622	PLK2	polo-like kinase 2
chr2_+_119841611	0.641	NM_001079863	DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chrX_+_154264931	0.637	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated (intronic transcript) 2 coagulation factor VIII-associated (intronic transcript) 3 coagulation factor VIII-associated (intronic transcript) 1
chr8_-_145122884	0.633	NM_000445	PLEC	plectin
chr1_-_6341553	0.626	NM_181866	ACOT7	acyl-CoA thioesterase 7
chr6_-_32929390	0.624		TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr1_+_154389945	0.623	NM_001193300 NM_022367 NM_001193302	SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr12_+_12935222	0.618	NM_003979	GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr1_-_109386112	0.615	NM_001142550 NM_001142551 NM_014969	WDR47	WD repeat domain 47
chr1_-_43692134	0.615	NM_001190880 NM_031207	HYI	hydroxypyruvate isomerase (putative)
chrX_+_106956115	0.615		MID2	midline 2
chr19_+_49972965	0.614	NM_001130852 NM_012116	CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c
chr3_-_51968995	0.611		PCBP4	poly(rC) binding protein 4
chr22_+_29807231	0.606	NM_006932 NM_134269 NM_134270	SMTN	smoothelin
chr10_-_105667976	0.605	NM_024928	OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1
chr11_+_60626505	0.599	NM_014207	CD5	CD5 molecule
chrX_-_8660170	0.596	NM_000216	KAL1	Kallmann syndrome 1 sequence
chr14_+_23700261	0.596	NM_006084	IRF9	interferon regulatory factor 9
chr14_-_60818263	0.592	NM_001017970	TMEM30B	transmembrane protein 30B
chr2_-_85490997	0.588	NM_001747	CAPG	capping protein (actin filament), gelsolin-like
chr16_-_17472238	0.587	NM_022166	XYLT1	xylosyltransferase I
chr11_-_102174032	0.574		MMP1	matrix metallopeptidase 1 (interstitial collagenase)
chr17_+_45965044	0.574	NM_017957	EPN3	epsin 3
chr22_+_21407066	0.574
chrX_-_84521320	0.572		POF1B	premature ovarian failure, 1B
chr3_+_36396948	0.566	NM_003149	STAC	SH3 and cysteine rich domain
chr10_-_105667871	0.562		OBFC1	oligonucleotide/oligosaccharide-binding fold containing 1
chr16_+_67328715	0.561		CDH1	cadherin 1, type 1, E-cadherin (epithelial)
chr1_+_32489426	0.558	NM_005356	LCK	lymphocyte-specific protein tyrosine kinase
chr2_-_96174865	0.557	NM_004418	DUSP2	dual specificity phosphatase 2
chr8_+_123863169	0.552		ZHX2	zinc fingers and homeoboxes 2
chr17_-_35911340	0.551	NM_032865	TNS4	tensin 4
chr22_+_41877470	0.550	NM_000714 NM_007311	TSPO	translocator protein (18kDa)
chr14_+_75058591	0.550		BATF	basic leucine zipper transcription factor, ATF-like
chr10_-_125841840	0.548	NM_014863 NM_015892	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr2_+_33514896	0.546	NM_170672	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr9_+_20648307	0.545	NM_017794	KIAA1797	KIAA1797
chr22_+_29819343	0.545		SMTN	smoothelin
chr17_-_59363352	0.543	NM_000626 NM_001039933 NM_021602	CD79B	CD79b molecule, immunoglobulin-associated beta
chr4_-_84250019	0.542	NM_001130716	PLAC8	placenta-specific 8
chr2_-_85490984	0.531		CAPG	capping protein (actin filament), gelsolin-like
chr4_-_122837590	0.530	NM_001154	ANXA5	annexin A5
chr9_-_21964825	0.526	NM_058197	CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr14_+_75058518	0.523	NM_006399	BATF	basic leucine zipper transcription factor, ATF-like
chr15_-_68971665	0.523	NM_020147	THAP10	THAP domain containing 10
chr3_-_79151232	0.522	NM_001145845 NM_133631	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr17_+_38238970	0.516		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chrX_-_62891712	0.516		ARHGEF9	Cdc42 guanine nucleotide exchange factor (GEF) 9
chr14_+_92330383	0.515	NM_005113	GOLGA5	golgin A5
chr17_+_12633504	0.513	NM_014859	ARHGAP44	Rho GTPase activating protein 44
chr19_+_702108	0.512	NM_173481	C19orf21	chromosome 19 open reading frame 21
chr13_-_39075200	0.509		LHFP	lipoma HMGIC fusion partner
chr19_+_4180494	0.508	NM_005755	EBI3	Epstein-Barr virus induced 3
chr5_+_131437383	0.508	NM_000758	CSF2	colony stimulating factor 2 (granulocyte-macrophage)
chr2_+_234292162	0.508	NM_007120	UGT1A4	UDP glucuronosyltransferase 1 family, polypeptide A4
chr5_-_73972055	0.504		ENC1	ectodermal-neural cortex 1 (with BTB-like domain)
chr1_-_11637058	0.502		FBXO2	F-box protein 2
chr2_+_17923404	0.498	NM_002252	KCNS3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr3_+_16901455	0.497	NM_001144382	PLCL2	phospholipase C-like 2
chr2_-_20288647	0.497	NM_001006946	SDC1	syndecan 1
chr2_-_161058550	0.496	NM_002897 NM_016836	RBMS1	RNA binding motif, single stranded interacting protein 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.47	2.72e-05	GO:0051239	regulation of multicellular organismal process
1.24	8.87e-05	GO:0023052	signaling
1.23	1.85e-03	GO:0007165	signal transduction
1.67	2.39e-03	GO:0032990	cell part morphogenesis
1.67	2.99e-03	GO:0048858	cell projection morphogenesis
1.68	7.51e-03	GO:0048812	neuron projection morphogenesis
1.43	9.56e-03	GO:0007154	cell communication
1.45	1.17e-02	GO:0050793	regulation of developmental process
6.89	1.23e-02	GO:0060678	dichotomous subdivision of terminal units involved in ureteric bud branching
1.75	1.61e-02	GO:0007411	axon guidance
1.55	1.63e-02	GO:0032989	cellular component morphogenesis
1.14	1.68e-02	GO:0050896	response to stimulus
1.45	1.73e-02	GO:0022008	neurogenesis
1.46	2.32e-02	GO:0048699	generation of neurons
1.60	2.38e-02	GO:0019226	transmission of nerve impulse
1.60	2.38e-02	GO:0035637	multicellular organismal signaling
1.55	2.46e-02	GO:0000902	cell morphogenesis
5.73	2.53e-02	GO:0060600	dichotomous subdivision of an epithelial terminal unit
5.73	2.53e-02	GO:0090184	positive regulation of kidney development
1.65	2.84e-02	GO:0007409	axonogenesis
1.48	3.10e-02	GO:2000026	regulation of multicellular organismal development
1.44	3.27e-02	GO:0040011	locomotion
1.57	3.65e-02	GO:0006935	chemotaxis
1.57	3.65e-02	GO:0042330	taxis
1.60	3.73e-02	GO:0031175	neuron projection development
1.52	3.99e-02	GO:0030030	cell projection organization
1.46	4.17e-02	GO:0007267	cell-cell signaling
6.13	4.92e-02	GO:0048880	sensory system development
6.13	4.92e-02	GO:0048892	lateral line nerve development
6.13	4.92e-02	GO:0048895	lateral line nerve glial cell differentiation
6.13	4.92e-02	GO:0048925	lateral line system development
6.13	4.92e-02	GO:0048937	lateral line nerve glial cell development
6.13	4.92e-02	GO:0050935	iridophore differentiation

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.27	8.88e-08	GO:0071944	cell periphery
1.27	1.85e-07	GO:0005886	plasma membrane
1.17	7.48e-07	GO:0016020	membrane
1.16	1.11e-03	GO:0044425	membrane part
1.27	1.33e-03	GO:0044459	plasma membrane part
1.62	2.19e-02	GO:0045202	synapse
1.49	3.55e-02	GO:0030054	cell junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.51	4.71e-02	GO:0008092	cytoskeletal protein binding
2.95	4.77e-02	GO:0003823	antigen binding