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• Activity deltas table
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Motif ID: E2F1..5.p2

Z-value: 6.392

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_135544138	26.842	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544170	26.335		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544214	21.273		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr7_-_99536966	12.561		MCM7	minichromosome maintenance complex component 7
chr7_-_99536929	12.499		MCM7	minichromosome maintenance complex component 7
chr11_-_33847507	12.165		LMO2	LIM domain only 2 (rhombotin-like 1)
chr7_-_99536852	11.818		MCM7	minichromosome maintenance complex component 7
chr7_-_99537362	10.993	NM_005916	MCM7	minichromosome maintenance complex component 7
chr11_-_33847937	10.809	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr11_-_33847834	10.616		LMO2	LIM domain only 2 (rhombotin-like 1)
chr22_+_34126104	10.204	NM_006739	MCM5	minichromosome maintenance complex component 5
chr11_-_33848013	10.184		LMO2	LIM domain only 2 (rhombotin-like 1)
chr6_-_52257500	10.129	NM_002388	MCM3	minichromosome maintenance complex component 3
chr22_+_34126154	9.563		MCM5	minichromosome maintenance complex component 5
chr6_-_52257475	9.184		MCM3	minichromosome maintenance complex component 3
chr2_-_136350404	9.128		MCM6	minichromosome maintenance complex component 6
chr6_-_52257431	8.857		MCM3	minichromosome maintenance complex component 3
chr8_-_124477639	8.550		ATAD2	ATPase family, AAA domain containing 2
chr2_-_136350472	8.334	NM_005915	MCM6	minichromosome maintenance complex component 6
chr4_-_56197115	8.334	NM_006681	NMU	neuromedin U
chr8_-_124477846	8.277		ATAD2	ATPase family, AAA domain containing 2
chr8_-_124477869	8.247	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr11_-_19219000	8.240	NM_024680	E2F8	E2F transcription factor 8
chr10_+_62208256	8.180		CDK1	cyclin-dependent kinase 1
chr10_+_62208094	8.180	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr6_-_27222556	8.153	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr11_-_19219720	7.932		E2F8	E2F transcription factor 8
chr22_+_34126294	7.812		MCM5	minichromosome maintenance complex component 5
chr13_+_33290254	7.796		RFC3	replication factor C (activator 1) 3, 38kDa
chr5_-_39110235	7.471		RICTOR	RPTOR independent companion of MTOR, complex 2
chr8_+_49036063	7.397		MCM4	minichromosome maintenance complex component 4
chr22_+_18485057	7.129		RANBP1	RAN binding protein 1
chr11_+_125001063	7.018		CHEK1	CHK1 checkpoint homolog (S. pombe)
chr2_+_232281491	6.891		PTMA	prothymosin, alpha
chr8_+_49036086	6.865		MCM4	minichromosome maintenance complex component 4
chr22_+_18485068	6.760		RANBP1	RAN binding protein 1
chr8_+_49035999	6.594	NM_005914 NM_182746	MCM4	minichromosome maintenance complex component 4
chr22_-_18484695	6.277		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr2_+_232281470	6.195	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr7_+_116380790	6.182		ST7	suppression of tumorigenicity 7
chr17_+_35697656	6.107		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr17_+_35697660	6.071	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr6_+_27208763	6.070	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr1_+_240078167	6.064		EXO1	exonuclease 1
chr1_+_240078094	6.042	NM_130398	EXO1	exonuclease 1
chr2_+_10180304	6.026	NM_001034	RRM2	ribonucleotide reductase M2
chr14_-_54438913	5.985	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr19_+_55579404	5.956	NM_002691	POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr22_+_18485076	5.797		RANBP1	RAN binding protein 1
chr8_-_120937215	5.766	NM_024094	DSCC1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr2_+_10180145	5.547	NM_001165931	RRM2	ribonucleotide reductase M2
chr17_+_35697677	5.503		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr20_-_5048443	5.503	NM_182649	PCNA	proliferating cell nuclear antigen
chr6_-_153345786	5.497	NM_012177	FBXO5	F-box protein 5
chr6_-_27208507	5.456	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr10_+_13243553	5.428	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr1_-_148050534	5.404	NM_001024599 NM_001161334	HIST2H2BF	histone cluster 2, H2bf
chr7_+_50314801	5.376	NM_006060	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr7_-_148212292	5.361		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148212312	5.348		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr19_+_55579272	5.297		POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr5_-_79986063	5.263		DHFR	dihydrofolate reductase
chr17_+_27288167	5.178		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr7_-_148212310	5.062		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148212230	5.043		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr1_-_147665783	5.038		HIST2H2BF	histone cluster 2, H2bf
chr7_-_148212336	4.968	NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr11_+_64785888	4.965	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chrX_-_53466273	4.794		SMC1A	structural maintenance of chromosomes 1A
chr13_+_33290205	4.792	NM_002915 NM_181558	RFC3	replication factor C (activator 1) 3, 38kDa
chrX_+_24621984	4.756	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr22_-_18484744	4.750	NM_022727 NM_182984	TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr3_+_128799961	4.746		MCM2	minichromosome maintenance complex component 2
chr15_-_64436045	4.702	NM_017858	TIPIN	TIMELESS interacting protein
chr17_+_27288152	4.698	NM_015355	SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr14_-_49224654	4.689		POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr22_+_18485145	4.593		RANBP1	RAN binding protein 1
chr16_+_1979959	4.558	NM_004209	SYNGR3	synaptogyrin 3
chr15_+_89061579	4.552	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chrX_-_152389209	4.532		TREX2 HAUS7	three prime repair exonuclease 2 HAUS augmin-like complex, subunit 7
chr16_-_87535106	4.523	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_+_87397686	4.473	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr5_-_79986104	4.460		DHFR	dihydrofolate reductase
chr14_-_49224847	4.442	NM_001197330 NM_001197331 NM_002692	POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr17_+_27288253	4.399		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr17_+_27288374	4.385
chr1_+_45822246	4.348	NM_001195193 NM_002482 NM_152298	NASP	nuclear autoantigenic sperm protein (histone-binding)
chrX_+_130985316	4.338	NM_001042452	MST4	serine/threonine protein kinase MST4
chr3_-_140148671	4.318	NM_023067	FOXL2	forkhead box L2
chr15_-_39412032	4.294	NM_007280	OIP5	Opa interacting protein 5
chr1_-_223682324	4.275		LBR	lamin B receptor
chrX_+_130984912	4.245	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr14_-_54727958	4.193	NM_001146015 NM_014750	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr16_-_84280004	4.139		GINS2	GINS complex subunit 2 (Psf2 homolog)
chr6_+_37245860	4.121	NM_002648	PIM1	pim-1 oncogene
chr1_-_26105230	4.065	NM_203401	STMN1	stathmin 1
chr5_-_79986539	4.060	NM_000791	DHFR	dihydrofolate reductase
chr6_-_27890496	4.036	NM_021066	HIST1H2AJ	histone cluster 1, H2aj
chr6_+_24883133	4.008	NM_015895	GMNN	geminin, DNA replication inhibitor
chr7_+_120378052	4.003	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr7_-_73306629	3.977		RFC2	replication factor C (activator 1) 2, 40kDa
chr16_-_84280088	3.963	NM_016095	GINS2	GINS complex subunit 2 (Psf2 homolog)
chr1_-_223682394	3.960	NM_002296	LBR	lamin B receptor
chr22_+_18485095	3.953		RANBP1	RAN binding protein 1
chr16_+_87397715	3.947		CDT1	chromatin licensing and DNA replication factor 1
chr1_+_210275752	3.935		DTL	denticleless homolog (Drosophila)
chr22_+_17847413	3.901	NM_001178010 NM_001178011 NM_003504	CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr5_-_37406835	3.882		NUP155	nucleoporin 155kDa
chr7_-_158190193	3.878	NM_017760	NCAPG2	non-SMC condensin II complex, subunit G2
chrX_-_137621060	3.841		FGF13	fibroblast growth factor 13
chr17_+_27288178	3.826		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr1_-_47552238	3.808	NM_001048166 NM_003035	STIL	SCL/TAL1 interrupting locus
chr1_-_26058434	3.789	NM_024037	C1orf135	chromosome 1 open reading frame 135
chr20_+_25336320	3.716	NM_021067	GINS1	GINS complex subunit 1 (Psf1 homolog)
chr5_-_37406939	3.692	NM_153485	NUP155	nucleoporin 155kDa
chr3_+_144321286	3.639	NM_004267	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr7_-_73306668	3.605	NM_002914 NM_181471	RFC2	replication factor C (activator 1) 2, 40kDa
chr2_+_74635019	3.603	NM_001381	DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr1_-_28113817	3.598	NM_002946	RPA2	replication protein A2, 32kDa
chr3_-_143350898	3.556	NM_001178138 NM_001178139	TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)
chr8_+_128817658	3.527		MYC	v-myc myelocytomatosis viral oncogene homolog (avian)
chr10_-_57791025	3.486	NM_001005413 NM_007057 NM_032997	ZWINT	ZW10 interactor
chr22_-_19685998	3.485		THAP7	THAP domain containing 7
chr10_-_57791000	3.479		ZWINT	ZW10 interactor
chr15_+_30694982	3.471	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr16_-_2970474	3.432	NM_004203 NM_182687	PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr3_+_44778284	3.432		KIF15	kinesin family member 15
chr1_-_28113540	3.428		RPA2	replication protein A2, 32kDa
chrX_+_48440068	3.424	NM_003173	SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr11_+_4072499	3.420	NM_001033	RRM1	ribonucleotide reductase M1
chr5_+_43157349	3.417		ZNF131	zinc finger protein 131
chr1_+_93317374	3.401	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr2_+_47483694	3.398		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr1_-_33275071	3.360	NM_013411	AK2	adenylate kinase 2
chrX_+_122923279	3.349		STAG2	stromal antigen 2
chr2_+_47483750	3.347	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr3_-_123036597	3.333	NM_001023570 NM_001023571	IQCB1	IQ motif containing B1
chr5_-_37406643	3.327	NM_004298	NUP155	nucleoporin 155kDa
chr7_+_138695144	3.326	NM_016019	LUC7L2	LUC7-like 2 (S. cerevisiae)
chr9_+_85785456	3.326	NM_024945	RMI1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr2_+_47483795	3.324		MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr22_+_17847467	3.323		CDC45	cell division cycle 45 homolog (S. cerevisiae)
chr3_+_44778212	3.285	NM_020242	KIF15	kinesin family member 15
chr16_-_2970390	3.279		PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr16_+_56983798	3.271	NM_001126129 NM_001126130 NM_022770	GINS3	GINS complex subunit 3 (Psf3 homolog)
chr20_+_25336328	3.270		GINS1	GINS complex subunit 1 (Psf1 homolog)
chr1_+_210275541	3.261	NM_016448	DTL	denticleless homolog (Drosophila)
chr3_+_128799902	3.252	NM_004526	MCM2	minichromosome maintenance complex component 2
chr8_-_27751207	3.219	NM_018492	PBK	PDZ binding kinase
chr1_-_26105477	3.188	NM_001145454 NM_005563	STMN1	stathmin 1
chr3_-_48204332	3.181		CDC25A	cell division cycle 25 homolog A (S. pombe)
chr6_+_27883877	3.172	NM_003509	HIST1H2AI HIST1H3F	histone cluster 1, H2ai histone cluster 1, H3f
chr3_+_128799964	3.143		MCM2	minichromosome maintenance complex component 2
chr8_-_95976599	3.115	NM_057749	CCNE2	cyclin E2
chr3_+_16901455	3.112	NM_001144382	PLCL2	phospholipase C-like 2
chrX_+_122923236	3.108	NM_001042750 NM_001042751 NM_006603	STAG2	stromal antigen 2
chr6_-_27968906	3.080	NM_003514	HIST1H2AM	histone cluster 1, H2am
chr12_+_131774225	3.070	NM_018663	PXMP2	peroxisomal membrane protein 2, 22kDa
chr7_+_138695236	3.035		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr15_-_35179614	3.033		MEIS2	Meis homeobox 2
chr8_+_21833162	2.990		XPO7	exportin 7
chr1_-_26105954	2.980	NM_203399	STMN1	stathmin 1
chr10_-_74676969	2.970	NM_015190	DNAJC9	DnaJ (Hsp40) homolog, subfamily C, member 9
chr7_+_138695241	2.961		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr8_+_128817494	2.959	NM_002467	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)
chr1_-_54076521	2.947		TMEM48	transmembrane protein 48
chr15_+_38774676	2.920		RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)
chr3_-_48204804	2.907	NM_001789 NM_201567	CDC25A	cell division cycle 25 homolog A (S. pombe)
chr3_+_14195231	2.897	NM_014463	LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr9_+_99785493	2.895		ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr12_-_131773972	2.855	NM_006231	POLE	polymerase (DNA directed), epsilon
chr19_-_46551670	2.848	NM_000660	TGFB1	transforming growth factor, beta 1
chr3_+_14195333	2.809		LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr19_-_46551172	2.797		TGFB1	transforming growth factor, beta 1
chr1_-_226712140	2.787	NM_033445	HIST3H2A	histone cluster 3, H2a
chr7_+_138695209	2.782		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr7_-_151764004	2.749	NM_170606	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3
chr3_-_150286812	2.744	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr1_-_243094404	2.710		HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr5_+_126140718	2.705	NM_001198557	LMNB1	lamin B1
chr1_+_62675296	2.702		USP1	ubiquitin specific peptidase 1
chr1_-_54076695	2.674	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr2_+_47863724	2.648	NM_000179	MSH6	mutS homolog 6 (E. coli)
chr16_+_29724926	2.615		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr8_+_21833111	2.613	NM_015024	XPO7	exportin 7
chr2_+_96845704	2.602	NM_017623 NM_199078	CNNM3	cyclin M3
chr11_-_56859900	2.601	NM_003146	SSRP1	structure specific recognition protein 1
chr1_+_37930763	2.594		CDCA8	cell division cycle associated 8
chr11_+_47543463	2.576	NM_001143984 NM_175732	PTPMT1	protein tyrosine phosphatase, mitochondrial 1
chr22_-_27467776	2.563	NM_001005735 NM_007194 NM_145862	CHEK2	CHK2 checkpoint homolog (S. pombe)
chr8_-_27751462	2.560		PBK	PDZ binding kinase
chr15_+_39412183	2.548	NM_001129897 NM_016359 NM_018454	NUSAP1	nucleolar and spindle associated protein 1
chr3_+_14195347	2.547		LSM3	LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_+_36912656	2.506		NIPBL	Nipped-B homolog (Drosophila)
chr13_-_29938029	2.490	NM_002128	HMGB1	high-mobility group box 1
chr17_+_78303317	2.490		TBCD	tubulin folding cofactor D
chr9_+_70509925	2.488	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr6_-_17814596	2.479	NM_005124	NUP153	nucleoporin 153kDa
chr2_+_177965734	2.475		AGPS	alkylglycerone phosphate synthase
chr9_+_99785277	2.472	NM_006401	ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.99	2.42e-35	GO:0090304	nucleic acid metabolic process
1.83	3.16e-33	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.47	1.08e-28	GO:0007049	cell cycle
2.81	2.90e-27	GO:0022403	cell cycle phase
2.62	1.80e-26	GO:0022402	cell cycle process
1.65	6.32e-25	GO:0034641	cellular nitrogen compound metabolic process
2.79	3.65e-24	GO:0051276	chromosome organization
2.84	5.57e-24	GO:0006259	DNA metabolic process
1.61	4.80e-23	GO:0006807	nitrogen compound metabolic process
1.49	1.03e-22	GO:0044260	cellular macromolecule metabolic process
4.33	2.25e-21	GO:0006260	DNA replication
2.67	4.95e-20	GO:0000278	mitotic cell cycle
1.39	1.22e-16	GO:0043170	macromolecule metabolic process
3.09	3.74e-16	GO:0051325	interphase
3.06	2.00e-15	GO:0051329	interphase of mitotic cell cycle
1.30	9.50e-15	GO:0044237	cellular metabolic process
4.14	2.71e-14	GO:0006310	DNA recombination
1.73	3.30e-14	GO:0016070	RNA metabolic process
2.90	3.37e-14	GO:0006281	DNA repair
2.47	8.78e-14	GO:0006974	response to DNA damage stimulus
5.61	1.08e-13	GO:0006261	DNA-dependent DNA replication
3.88	2.18e-13	GO:0000082	G1/S transition of mitotic cell cycle
4.42	2.98e-13	GO:0071824	protein-DNA complex subunit organization
2.41	5.05e-13	GO:0016071	mRNA metabolic process
3.92	6.80e-13	GO:0071103	DNA conformation change
1.73	1.07e-12	GO:0006996	organelle organization
1.28	1.20e-12	GO:0044238	primary metabolic process
4.47	1.24e-12	GO:0065004	protein-DNA complex assembly
4.44	3.82e-12	GO:0034728	nucleosome organization
1.69	4.00e-12	GO:0034645	cellular macromolecule biosynthetic process
4.13	4.54e-12	GO:0006323	DNA packaging
1.65	5.66e-12	GO:0010467	gene expression
4.60	6.73e-12	GO:0031497	chromatin assembly
3.29	1.13e-11	GO:0000375	RNA splicing, via transesterification reactions
2.22	1.18e-11	GO:0006396	RNA processing
2.55	1.27e-11	GO:0000279	M phase
2.61	1.37e-11	GO:0006397	mRNA processing
3.32	1.39e-11	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.32	1.39e-11	GO:0000398	nuclear mRNA splicing, via spliceosome
1.67	1.52e-11	GO:0009059	macromolecule biosynthetic process
2.42	4.09e-11	GO:0006325	chromatin organization
2.77	8.72e-11	GO:0008380	RNA splicing
3.74	9.30e-11	GO:0006333	chromatin assembly or disassembly
2.16	1.43e-10	GO:0051726	regulation of cell cycle
4.43	1.51e-10	GO:0006334	nucleosome assembly
1.23	1.80e-10	GO:0008152	metabolic process
2.59	1.87e-10	GO:0010564	regulation of cell cycle process
3.85	6.71e-10	GO:0051320	S phase
1.49	9.05e-10	GO:0044249	cellular biosynthetic process
3.81	1.94e-09	GO:0000084	S phase of mitotic cell cycle
7.34	3.75e-09	GO:0006271	DNA strand elongation involved in DNA replication
2.42	8.21e-09	GO:0034622	cellular macromolecular complex assembly
6.81	2.17e-08	GO:0022616	DNA strand elongation
1.45	2.25e-08	GO:0009058	biosynthetic process
1.43	4.01e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.94	5.18e-08	GO:0065003	macromolecular complex assembly
1.43	8.04e-08	GO:0071842	cellular component organization at cellular level
2.76	2.13e-07	GO:0000075	cell cycle checkpoint
2.72	2.33e-07	GO:0071156	regulation of cell cycle arrest
7.48	2.52e-07	GO:0006270	DNA-dependent DNA replication initiation
1.33	1.44e-06	GO:0071840	cellular component organization or biogenesis
1.33	1.68e-06	GO:0016043	cellular component organization
7.29	1.93e-06	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
1.10	2.17e-06	GO:0009987	cellular process
1.63	2.47e-06	GO:0044085	cellular component biogenesis
2.45	2.96e-06	GO:0000280	nuclear division
2.45	2.96e-06	GO:0007067	mitosis
9.35	3.76e-06	GO:0071897	DNA biosynthetic process
3.30	4.53e-06	GO:0051028	mRNA transport
2.00	4.90e-06	GO:0034621	cellular macromolecular complex subunit organization
1.76	5.62e-06	GO:0033554	cellular response to stress
1.74	6.25e-06	GO:0043933	macromolecular complex subunit organization
2.37	1.01e-05	GO:0000087	M phase of mitotic cell cycle
2.36	1.18e-05	GO:0048285	organelle fission
1.64	1.18e-05	GO:0022607	cellular component assembly
3.11	1.25e-05	GO:0050657	nucleic acid transport
3.11	1.25e-05	GO:0050658	RNA transport
3.11	1.25e-05	GO:0051236	establishment of RNA localization
3.40	1.39e-05	GO:0051321	meiotic cell cycle
4.44	1.88e-05	GO:0051053	negative regulation of DNA metabolic process
3.03	2.49e-05	GO:0006403	RNA localization
6.73	3.31e-05	GO:0006298	mismatch repair
1.40	3.36e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
3.32	4.89e-05	GO:0007126	meiosis
3.32	4.89e-05	GO:0051327	M phase of meiotic cell cycle
6.41	7.11e-05	GO:0090329	regulation of DNA-dependent DNA replication
4.30	8.60e-05	GO:0032200	telomere organization
6.86	1.04e-04	GO:2000104	negative regulation of DNA-dependent DNA replication
1.66	1.05e-04	GO:0006351	transcription, DNA-dependent
3.44	1.48e-04	GO:0000216	M/G1 transition of mitotic cell cycle
1.37	1.68e-04	GO:0010556	regulation of macromolecule biosynthetic process
4.81	2.03e-04	GO:0008156	negative regulation of DNA replication
6.50	2.28e-04	GO:0032201	telomere maintenance via semi-conservative replication
1.36	2.34e-04	GO:0010468	regulation of gene expression
1.30	2.39e-04	GO:0060255	regulation of macromolecule metabolic process
2.76	2.50e-04	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.34	3.61e-04	GO:0051171	regulation of nitrogen compound metabolic process
4.15	3.81e-04	GO:0000723	telomere maintenance
1.69	4.14e-04	GO:0071844	cellular component assembly at cellular level
6.17	4.67e-04	GO:0000722	telomere maintenance via recombination
1.34	5.32e-04	GO:0031326	regulation of cellular biosynthetic process
1.61	7.44e-04	GO:0010605	negative regulation of macromolecule metabolic process
4.43	7.51e-04	GO:0006369	termination of RNA polymerase II transcription
1.37	8.65e-04	GO:0051252	regulation of RNA metabolic process
1.33	8.79e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33	9.10e-04	GO:0009889	regulation of biosynthetic process
1.76	9.15e-04	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.99	1.41e-03	GO:0007059	chromosome segregation
1.75	1.44e-03	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
6.23	1.52e-03	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus
6.23	1.52e-03	GO:0016444	somatic cell DNA recombination
1.57	1.52e-03	GO:0009892	negative regulation of metabolic process
5.18	1.54e-03	GO:0006312	mitotic recombination
5.61	1.66e-03	GO:0002200	somatic diversification of immune receptors
1.26	1.70e-03	GO:0031323	regulation of cellular metabolic process
1.26	1.86e-03	GO:0080090	regulation of primary metabolic process
6.73	2.35e-03	GO:0006297	nucleotide-excision repair, DNA gap filling
3.54	2.49e-03	GO:0031124	mRNA 3'-end processing
1.72	2.54e-03	GO:0051172	negative regulation of nitrogen compound metabolic process
1.97	2.55e-03	GO:0016568	chromatin modification
1.54	2.64e-03	GO:0032774	RNA biosynthetic process
2.41	3.03e-03	GO:0006913	nucleocytoplasmic transport
8.73	3.07e-03	GO:0002566	somatic diversification of immune receptors via somatic mutation
8.73	3.07e-03	GO:0016446	somatic hypermutation of immunoglobulin genes
1.70	3.15e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
2.37	4.11e-03	GO:0051169	nuclear transport
3.28	4.69e-03	GO:0031123	RNA 3'-end processing
1.98	4.72e-03	GO:0051301	cell division
6.31	4.95e-03	GO:0007062	sister chromatid cohesion
3.53	5.20e-03	GO:0006406	mRNA export from nucleus
4.64	6.43e-03	GO:0010833	telomere maintenance via telomere lengthening
1.34	7.72e-03	GO:0006355	regulation of transcription, DNA-dependent
1.55	7.76e-03	GO:0031324	negative regulation of cellular metabolic process
3.03	9.73e-03	GO:0051168	nuclear export
1.65	9.77e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.22	1.02e-02	GO:0019222	regulation of metabolic process
6.41	1.62e-02	GO:0016447	somatic recombination of immunoglobulin gene segments
1.61	2.25e-02	GO:0009890	negative regulation of biosynthetic process
8.42	2.72e-02	GO:0000731	DNA synthesis involved in DNA repair
5.32	3.13e-02	GO:0016445	somatic diversification of immunoglobulins
3.13	3.27e-02	GO:0006302	double-strand break repair
3.13	3.27e-02	GO:0006405	RNA export from nucleus
1.49	3.66e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.37	3.73e-02	GO:0051052	regulation of DNA metabolic process
3.37	3.97e-02	GO:0007127	meiosis I
4.26	4.56e-02	GO:0000724	double-strand break repair via homologous recombination
4.26	4.56e-02	GO:0000725	recombinational repair
4.26	4.56e-02	GO:0007131	reciprocal meiotic recombination
3.49	4.78e-02	GO:0007051	spindle organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.64	1.80e-53	GO:0005634	nucleus
2.15	3.06e-48	GO:0044428	nuclear part
2.20	1.64e-42	GO:0031981	nuclear lumen
1.34	2.78e-40	GO:0043227	membrane-bounded organelle
1.34	3.55e-40	GO:0043231	intracellular membrane-bounded organelle
1.99	4.34e-38	GO:0070013	intracellular organelle lumen
1.29	5.80e-38	GO:0043226	organelle
1.29	1.17e-37	GO:0043229	intracellular organelle
1.95	8.20e-37	GO:0031974	membrane-enclosed lumen
2.35	9.46e-37	GO:0005654	nucleoplasm
1.95	2.24e-36	GO:0043233	organelle lumen
3.16	1.21e-32	GO:0005694	chromosome
1.21	3.06e-32	GO:0044424	intracellular part
1.47	6.24e-30	GO:0044446	intracellular organelle part
1.19	1.12e-29	GO:0005622	intracellular
1.45	4.71e-29	GO:0044422	organelle part
3.07	7.92e-25	GO:0044427	chromosomal part
1.56	1.14e-21	GO:0032991	macromolecular complex
3.29	3.72e-15	GO:0000785	chromatin
1.56	5.81e-15	GO:0043228	non-membrane-bounded organelle
1.56	5.81e-15	GO:0043232	intracellular non-membrane-bounded organelle
4.64	1.20e-13	GO:0032993	protein-DNA complex
2.15	1.61e-13	GO:0044451	nucleoplasm part
3.19	1.30e-12	GO:0000228	nuclear chromosome
2.23	2.39e-10	GO:0030529	ribonucleoprotein complex
3.23	3.14e-10	GO:0044454	nuclear chromosome part
2.79	5.81e-09	GO:0016604	nuclear body
4.78	1.44e-08	GO:0000786	nucleosome
1.39	3.08e-08	GO:0043234	protein complex
3.29	7.30e-08	GO:0005681	spliceosomal complex
1.05	7.66e-08	GO:0044464	cell part
1.05	8.05e-08	GO:0005623	cell
5.78	1.34e-07	GO:0005657	replication fork
3.74	4.37e-06	GO:0071013	catalytic step 2 spliceosome
6.17	8.11e-05	GO:0043596	nuclear replication fork
9.82	1.28e-04	GO:0042555	MCM complex
2.69	3.28e-04	GO:0000775	chromosome, centromeric region
6.73	4.08e-04	GO:0030894	replisome
6.73	4.08e-04	GO:0043601	nuclear replisome
7.48	5.45e-04	GO:0032300	mismatch repair complex
1.77	9.40e-04	GO:0005730	nucleolus
2.50	2.15e-03	GO:0000793	condensed chromosome
5.61	3.10e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
8.42	4.73e-03	GO:0035098	ESC/E(Z) complex
1.57	6.60e-03	GO:0031975	envelope
1.57	6.62e-03	GO:0031967	organelle envelope
3.74	7.13e-03	GO:0000792	heterochromatin
3.34	1.44e-02	GO:0034708	methyltransferase complex
3.34	1.44e-02	GO:0035097	histone methyltransferase complex
2.81	1.61e-02	GO:0000790	nuclear chromatin
5.28	1.79e-02	GO:0031519	PcG protein complex
2.21	4.38e-02	GO:0031965	nuclear membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.73	4.46e-30	GO:0003676	nucleic acid binding
1.75	4.01e-20	GO:0003677	DNA binding
1.22	1.13e-11	GO:0005515	protein binding
1.95	2.12e-10	GO:0003723	RNA binding
1.11	2.71e-10	GO:0005488	binding
3.11	5.73e-10	GO:0043566	structure-specific DNA binding
1.47	1.20e-08	GO:0000166	nucleotide binding
4.41	3.55e-07	GO:0003697	single-stranded DNA binding
3.04	1.85e-06	GO:0003690	double-stranded DNA binding
8.02	1.18e-05	GO:0030983	mismatched DNA binding
3.62	1.03e-04	GO:0008094	DNA-dependent ATPase activity
11.22	2.77e-04	GO:0032135	DNA insertion or deletion binding
4.99	6.19e-04	GO:0034061	DNA polymerase activity
2.33	1.13e-03	GO:0003682	chromatin binding
5.14	1.21e-03	GO:0003887	DNA-directed DNA polymerase activity
3.83	1.63e-03	GO:0003684	damaged DNA binding
1.38	7.35e-03	GO:0032559	adenyl ribonucleotide binding
1.38	7.86e-03	GO:0005524	ATP binding
1.49	8.12e-03	GO:0030528	transcription regulator activity
1.37	9.56e-03	GO:0030554	adenyl nucleotide binding
1.49	9.93e-03	GO:0001071	nucleic acid binding transcription factor activity
1.49	9.93e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
4.16	3.40e-02	GO:0002039	p53 binding
11.22	3.58e-02	GO:0032138	single base insertion or deletion binding
1.71	4.63e-02	GO:0003712	transcription cofactor activity