Motif ID: NRF1.p2

Z-value: 4.188


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1290387650.953.4e-08Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_91738953 6.063 NM_001134419
NM_003503
CDC7

cell division cycle 7 homolog (S. cerevisiae)

chr1_+_91739241 5.511 NM_001134420
CDC7
cell division cycle 7 homolog (S. cerevisiae)
chr7_+_99865340 5.064 MEPCE
methylphosphate capping enzyme
chr7_+_99865189 4.301 NM_019606
MEPCE
methylphosphate capping enzyme
chr14_+_100263066 3.612 DLK1
delta-like 1 homolog (Drosophila)
chr19_-_40928131 3.534 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr21_-_32573195 3.530 NM_018944
MIS18A
MIS18 kinetochore protein homolog A (S. pombe)
chr6_-_153346283 3.502 NM_001142522
FBXO5
F-box protein 5
chr5_+_162820094 3.443 NM_001142556
NM_001142557
NM_012484
NM_012485
HMMR



hyaluronan-mediated motility receptor (RHAMM)



chr11_+_64785888 3.378 NM_002689
POLA2
polymerase (DNA directed), alpha 2 (70kD subunit)
chr14_+_100263028 3.361 DLK1
delta-like 1 homolog (Drosophila)
chr5_-_88215034 3.199 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr19_+_5574119 3.198 SAFB
scaffold attachment factor B
chr19_-_48950912 3.150 C19orf61
chromosome 19 open reading frame 61
chr9_+_109085643 3.080 RAD23B
RAD23 homolog B (S. cerevisiae)
chr5_-_88214720 2.989 MEF2C
myocyte enhancer factor 2C
chr15_-_66900266 2.979 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr13_-_49554089 2.882 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr1_+_3763704 2.880 NM_004402
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr19_-_55124490 2.861 NUP62
nucleoporin 62kDa
chr17_-_55324859 2.855 NM_001193609
NM_001193610
NM_001193611
NM_001193612
NM_001193613
NM_016261
TUBD1





tubulin, delta 1





chr16_+_31098962 2.845 FUS
fused in sarcoma
chr20_-_57051231 2.828 NM_016045
SLMO2
slowmo homolog 2 (Drosophila)
chrX_-_153360789 2.823 NM_006014
LAGE3
L antigen family, member 3
chr19_-_48950811 2.803 C19orf61
chromosome 19 open reading frame 61
chr14_+_100262916 2.799 DLK1
delta-like 1 homolog (Drosophila)
chr14_+_100262943 2.762 NM_003836
DLK1
delta-like 1 homolog (Drosophila)
chr19_-_55124543 2.705 NUP62
nucleoporin 62kDa
chr19_-_48950955 2.702 NM_019108
C19orf61
chromosome 19 open reading frame 61
chr19_-_2279566 2.658 NM_016199
LSM7
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chrX_+_49103560 2.658 NM_012196
NM_001472
NM_001474
NM_001475
NM_021123
NM_001477
NM_001127200
NM_001127212
GAGE8
GAGE1
GAGE2C
GAGE4
GAGE5
GAGE6
GAGE7
GAGE12I
GAGE2E
GAGE12B
GAGE2A
G antigen 8
G antigen 1
G antigen 2C
G antigen 4
G antigen 5
G antigen 6
G antigen 7
G antigen 12I
G antigen 2E
G antigen 12B
G antigen 2A
chr6_-_39305203 2.644 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr19_-_60462152 2.637 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr1_+_165456572 2.615 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr6_-_31882558 2.612 LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr5_+_112340326 2.595 NM_152624
DCP2
DCP2 decapping enzyme homolog (S. cerevisiae)
chr6_+_135544170 2.580 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr16_+_31098963 2.575 FUS
fused in sarcoma
chr21_-_33065849 2.548 NM_013329
NM_016631
GCFC1

GC-rich sequence DNA-binding factor 1

chr6_+_135544138 2.546 NM_001130172
NM_001130173
NM_001161656
NM_001161657
NM_001161658
NM_001161659
NM_001161660
NM_005375
MYB







v-myb myeloblastosis viral oncogene homolog (avian)







chr19_-_55124491 2.494 NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chr8_+_26491507 2.486 DPYSL2
dihydropyrimidinase-like 2
chr16_+_27122307 2.483 NM_024773
JMJD5
jumonji domain containing 5
chr5_+_61637993 2.456 KIF2A
kinesin heavy chain member 2A
chr9_+_109085386 2.422 RAD23B
RAD23 homolog B (S. cerevisiae)
chr22_-_19686351 2.387 NM_001008695
NM_030573
THAP7

THAP domain containing 7

chr6_-_41148061 2.382 NM_145063
C6orf130
chromosome 6 open reading frame 130
chr1_+_35507197 2.341 ZMYM4
zinc finger, MYM-type 4
chr16_+_31098971 2.337 FUS
fused in sarcoma
chr16_+_27122796 2.330 NM_001145348
JMJD5
jumonji domain containing 5
chr6_+_135544214 2.323 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr6_-_31882704 2.306 NM_021177
LSM2
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr19_-_60461732 2.283 NM_014931
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr16_+_170334 2.280 NM_005331
HBQ1
hemoglobin, theta 1
chr22_+_43938389 2.267 NM_007172
NUP50
nucleoporin 50kDa
chr16_+_31098959 2.252 FUS
fused in sarcoma
chr16_+_2419388 2.234 NM_001761
CCNF
cyclin F
chr19_+_10932792 2.188 NM_001128849
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr9_+_109085372 2.184 RAD23B
RAD23 homolog B (S. cerevisiae)
chr14_+_74606051 2.132 NM_001042430
NM_024643
FAM164C

family with sequence similarity 164, member C

chr8_+_21833111 2.128 NM_015024
XPO7
exportin 7
chr1_+_181075104 2.112 DHX9
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr16_-_2330738 2.093 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr17_-_45110339 2.087 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr16_+_87397686 2.083 NM_030928
CDT1
chromatin licensing and DNA replication factor 1
chr8_+_61753793 2.051 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr6_+_43089908 2.047 KLHDC3
kelch domain containing 3
chr17_+_7427849 2.043 MPDU1
mannose-P-dolichol utilization defect 1
chr13_+_49554307 2.043 DLEU1
deleted in lymphocytic leukemia 1 (non-protein coding)
chr16_-_2330712 2.039 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr19_-_55124546 2.033 NM_012346
NM_153718
NM_153719
NM_001193357
NM_172374
NUP62



IL4I1
nucleoporin 62kDa



interleukin 4 induced 1
chr8_+_21833162 2.030 XPO7
exportin 7
chr9_+_132990760 2.026 NM_005085
NUP214
nucleoporin 214kDa
chr18_+_10516022 2.007 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr17_+_7427688 1.984 NM_004870
MPDU1
mannose-P-dolichol utilization defect 1
chr18_+_10515861 1.981 NM_003826
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr19_+_63747829 1.977 TRIM28
tripartite motif containing 28
chr9_+_107496638 1.975 NM_018112
TMEM38B
transmembrane protein 38B
chr16_+_84204424 1.971 NM_014615
KIAA0182
KIAA0182
chr3_-_47798341 1.960 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr9_+_109085337 1.936 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr16_+_29734785 1.932 C16orf53
chromosome 16 open reading frame 53
chr1_+_210275541 1.919 NM_016448
DTL
denticleless homolog (Drosophila)
chr21_+_44377974 1.902 C21orf33
chromosome 21 open reading frame 33
chr1_-_23977330 1.900 LOC100506963
hypothetical LOC100506963
chr17_-_77478835 1.900 NM_002359
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr4_-_121207338 1.894 NM_002358
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chr18_+_10516044 1.878 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr1_+_181075059 1.869 NM_001357
DHX9
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr3_-_47798372 1.868 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr6_+_26307691 1.854 NM_003522
HIST1H2BF
histone cluster 1, H2bf
chr19_+_5574143 1.850 NM_002967
SAFB
scaffold attachment factor B
chr10_-_69901735 1.847 NM_001080449
DNA2
DNA replication helicase 2 homolog (yeast)
chr19_-_55124764 1.845 NM_016553
NUP62
nucleoporin 62kDa
chr17_+_7096095 1.840 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr6_+_41148869 1.837 NFYA
nuclear transcription factor Y, alpha
chr16_+_87397715 1.814 CDT1
chromatin licensing and DNA replication factor 1
chr10_+_127502080 1.794 NM_016567
NM_078468
NM_078469
BCCIP


BRCA2 and CDKN1A interacting protein


chr17_+_46692908 1.793 UTP18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr16_+_29734990 1.778 NM_024516
C16orf53
chromosome 16 open reading frame 53
chr6_+_43089933 1.778 KLHDC3
kelch domain containing 3
chr7_-_124357272 1.775 NM_001042594
NM_015450
POT1

protection of telomeres 1 homolog (S. pombe)

chr19_-_5671158 1.771 NM_004793
LONP1
lon peptidase 1, mitochondrial
chr21_+_39674112 1.758 WRB
tryptophan rich basic protein
chr19_+_10932583 1.757 NM_001128844
NM_003072
SMARCA4

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

chr6_+_89912464 1.756 NM_001010853
PM20D2
peptidase M20 domain containing 2
chr6_-_35996794 1.753 SRPK1
SRSF protein kinase 1
chr9_-_139100923 1.745 LOC100289341
similar to hCG2022304
chr21_+_39674082 1.728 NM_004627
WRB
tryptophan rich basic protein
chrX_-_129127361 1.718 AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr17_+_46692881 1.714 UTP18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr5_+_665404 1.712 NM_018140
CEP72
centrosomal protein 72kDa
chr21_+_39739663 1.709 NM_001001713
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr1_+_244954153 1.704 SCCPDH
saccharopine dehydrogenase (putative)
chr8_-_145485822 1.704 BOP1
block of proliferation 1
chr6_+_43089947 1.700 KLHDC3
kelch domain containing 3
chr15_-_66900143 1.693 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_+_107318854 1.669 DLD
dihydrolipoamide dehydrogenase
chr7_+_107318852 1.665 DLD
dihydrolipoamide dehydrogenase
chr3_-_25806500 1.664 NM_001145294
NGLY1
N-glycanase 1
chr12_-_52356375 1.663 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chrX_-_129127310 1.662 AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr18_+_10516095 1.659 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr8_-_117956062 1.657 RAD21
RAD21 homolog (S. pombe)
chr1_-_40121756 1.656 NM_017646
TRIT1
tRNA isopentenyltransferase 1
chr19_-_60610792 1.645 UBE2S
ubiquitin-conjugating enzyme E2S
chr8_-_117956226 1.644 NM_006265
RAD21
RAD21 homolog (S. pombe)
chr16_+_31098931 1.634 NM_001170634
NM_001170937
NM_004960
FUS


fused in sarcoma


chr17_-_74289901 1.633 NM_004762
NM_017456
CYTH1

cytohesin 1

chr10_+_21863099 1.630 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr5_+_665454 1.630 CEP72
centrosomal protein 72kDa
chr7_+_107318821 1.621 NM_000108
DLD
dihydrolipoamide dehydrogenase
chr9_+_114182216 1.619 HSDL2
hydroxysteroid dehydrogenase like 2
chr1_-_38046270 1.618 YRDC
yrdC domain containing (E. coli)
chr11_-_133599628 1.615 NM_015261
NCAPD3
non-SMC condensin II complex, subunit D3
chr19_+_63747678 1.612 TRIM28
tripartite motif containing 28
chr8_-_145485879 1.610 BOP1
block of proliferation 1
chr1_-_38046433 1.600 YRDC
yrdC domain containing (E. coli)
chr8_+_31010791 1.594 WRN
Werner syndrome, RecQ helicase-like
chr4_-_2213645 1.593 NM_024511
POLN
HAUS3
polymerase (DNA directed) nu
HAUS augmin-like complex, subunit 3
chr18_+_12938010 1.591 SEH1L
SEH1-like (S. cerevisiae)
chr19_-_60610971 1.579 UBE2S
ubiquitin-conjugating enzyme E2S
chrX_-_129127484 1.578 NM_145813
NM_001130847
NM_004208
NM_145812
AIFM1



apoptosis-inducing factor, mitochondrion-associated, 1



chr1_-_38046410 1.577 YRDC
yrdC domain containing (E. coli)
chr12_-_122283598 1.566 MPHOSPH9
M-phase phosphoprotein 9
chr14_-_101623097 1.561 HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr15_+_40575142 1.561 SNAP23
synaptosomal-associated protein, 23kDa
chr15_-_63264494 1.556 NM_006660
CLPX
ClpX caseinolytic peptidase X homolog (E. coli)
chr1_-_38046439 1.552 NM_024640
YRDC
yrdC domain containing (E. coli)
chr12_+_68039728 1.552 NM_006530
YEATS4
YEATS domain containing 4
chr6_+_43089964 1.551 KLHDC3
kelch domain containing 3
chr19_+_43801524 1.549 NM_013234
EIF3K
eukaryotic translation initiation factor 3, subunit K
chr16_+_83291107 1.548 USP10
ubiquitin specific peptidase 10
chr5_+_61637822 1.542 KIF2A
kinesin heavy chain member 2A
chr7_-_154425510 1.542 NM_007349
PAXIP1
PAX interacting (with transcription-activation domain) protein 1
chrX_-_153360411 1.540 LAGE3
L antigen family, member 3
chr2_+_96365233 1.539 NCAPH
non-SMC condensin I complex, subunit H
chr6_-_35996915 1.539 NM_003137
SRPK1
SRSF protein kinase 1
chr8_-_145485897 1.536 BOP1
block of proliferation 1
chr17_+_46692891 1.529 NM_016001
UTP18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr10_+_21863272 1.527 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr11_+_108040983 1.513 NM_004398
DDX10
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr9_+_114182009 1.502 NM_001195822
NM_032303
HSDL2

hydroxysteroid dehydrogenase like 2

chr18_-_12874140 1.497 NM_002828
NM_080422
NM_080423
PTPN2


protein tyrosine phosphatase, non-receptor type 2


chr15_-_35180656 1.493 NM_002399
MEIS2
Meis homeobox 2
chr19_-_60461656 1.489 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr16_+_2195709 1.488 MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr16_+_29735208 1.481 C16orf53
chromosome 16 open reading frame 53
chr1_+_210275752 1.478 DTL
denticleless homolog (Drosophila)
chr17_+_75849221 1.477 NM_020914
NM_020954
RNF213

ring finger protein 213

chr6_+_43089970 1.470 KLHDC3
kelch domain containing 3
chrX_+_37429927 1.467 NM_021083
XK
X-linked Kx blood group (McLeod syndrome)
chr2_+_254843 1.460 NM_001040649
NM_004300
NM_007099
ACP1


acid phosphatase 1, soluble


chr1_+_159395853 1.439 NM_001014443
NM_012475
USP21

ubiquitin specific peptidase 21

chr6_+_43089980 1.434 KLHDC3
kelch domain containing 3
chr3_+_73128771 1.433 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr12_+_92295738 1.431 NM_019094
NM_199040
NUDT4

NUDT4P1
nudix (nucleoside diphosphate linked moiety X)-type motif 4

nudix (nucleoside diphosphate linked moiety X)-type motif 4 pseudogene 1
chr5_+_61637701 1.427 NM_001098511
NM_004520
KIF2A

kinesin heavy chain member 2A

chr21_+_39674138 1.427 WRB
tryptophan rich basic protein
chr16_+_83291097 1.421 USP10
ubiquitin specific peptidase 10
chr1_+_159395912 1.417 USP21
ubiquitin specific peptidase 21
chrX_+_49241061 1.415 NM_001127212
GAGE8
GAGE1
GAGE2C
GAGE2A
G antigen 8
G antigen 1
G antigen 2C
G antigen 2A
chr16_+_83291112 1.415 USP10
ubiquitin specific peptidase 10
chr19_+_63747638 1.413 NM_005762
TRIM28
tripartite motif containing 28
chr19_+_19164732 1.412 RFXANK
regulatory factor X-associated ankyrin-containing protein
chr6_-_35996867 1.411 SRPK1
SRSF protein kinase 1
chr10_-_73646010 1.407 ASCC1
activating signal cointegrator 1 complex subunit 1
chr12_-_52356123 1.403 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr6_-_26307418 1.402 NM_021065
NM_003530
HIST1H2AD
HIST1H3D
histone cluster 1, H2ad
histone cluster 1, H3d
chr18_-_5286013 1.397 NM_001143823
NM_003409
ZFP161

zinc finger protein 161 homolog (mouse)

chr19_-_14390853 1.394 DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr17_+_7151368 1.389 NM_001970
EIF5A
eukaryotic translation initiation factor 5A
chr3_+_185335762 1.384 EIF2B5
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
chr22_-_19543012 1.365 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_+_43089991 1.364 KLHDC3
kelch domain containing 3
chr3_+_185335856 1.364 EIF2B5
eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
chr5_-_175748533 1.364 NOP16
NOP16 nucleolar protein homolog (yeast)
chr21_+_34367678 1.362 NM_032476
NM_006933
MRPS6
SLC5A3
mitochondrial ribosomal protein S6
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
chr12_-_26982144 1.361 C12orf11
chromosome 12 open reading frame 11
chr8_+_42368550 1.351 VDAC3
voltage-dependent anion channel 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 2.24e-33 GO:0044260 cellular macromolecule metabolic process
1.70 3.73e-28 GO:0090304 nucleic acid metabolic process
1.59 1.32e-26 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38 5.02e-25 GO:0043170 macromolecule metabolic process
1.31 1.45e-24 GO:0044237 cellular metabolic process
1.47 1.72e-20 GO:0034641 cellular nitrogen compound metabolic process
2.27 2.40e-20 GO:0051276 chromosome organization
1.45 2.79e-19 GO:0006807 nitrogen compound metabolic process
1.66 2.18e-18 GO:0016070 RNA metabolic process
2.17 8.11e-18 GO:0006396 RNA processing
1.62 2.08e-17 GO:0010467 gene expression
1.24 3.80e-17 GO:0008152 metabolic process
1.26 8.92e-17 GO:0044238 primary metabolic process
2.17 5.80e-15 GO:0016071 mRNA metabolic process
1.96 4.91e-13 GO:0022403 cell cycle phase
2.00 6.89e-12 GO:0006259 DNA metabolic process
2.26 7.20e-12 GO:0006397 mRNA processing
1.56 7.39e-12 GO:0006996 organelle organization
2.13 1.29e-11 GO:0006325 chromatin organization
2.35 1.62e-10 GO:0008380 RNA splicing
2.66 1.73e-10 GO:0000375 RNA splicing, via transesterification reactions
2.12 4.80e-10 GO:0000279 M phase
2.65 5.28e-10 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.65 5.28e-10 GO:0000398 nuclear mRNA splicing, via spliceosome
1.78 5.69e-10 GO:0022402 cell cycle process
1.39 2.62e-09 GO:0044267 cellular protein metabolic process
1.89 3.20e-09 GO:0000278 mitotic cell cycle
1.65 5.42e-09 GO:0007049 cell cycle
1.91 1.81e-08 GO:0006974 response to DNA damage stimulus
3.67 4.74e-08 GO:0006405 RNA export from nucleus
2.11 5.73e-08 GO:0006281 DNA repair
2.73 1.15e-07 GO:0071103 DNA conformation change
3.33 1.35e-07 GO:0051168 nuclear export
2.79 2.02e-07 GO:0006403 RNA localization
1.44 2.53e-07 GO:0034645 cellular macromolecule biosynthetic process
3.73 3.00e-07 GO:0006406 mRNA export from nucleus
2.80 3.02e-07 GO:0050657 nucleic acid transport
2.80 3.02e-07 GO:0050658 RNA transport
2.80 3.02e-07 GO:0051236 establishment of RNA localization
2.17 3.36e-07 GO:0000087 M phase of mitotic cell cycle
1.33 5.33e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.43 5.84e-07 GO:0009059 macromolecule biosynthetic process
2.86 7.10e-07 GO:0051028 mRNA transport
1.63 9.29e-07 GO:0033554 cellular response to stress
2.68 9.85e-07 GO:0006333 chromatin assembly or disassembly
2.13 1.12e-06 GO:0048285 organelle fission
2.15 1.36e-06 GO:0000280 nuclear division
2.15 1.36e-06 GO:0007067 mitosis
2.75 2.66e-06 GO:0006323 DNA packaging
2.39 3.40e-06 GO:0051169 nuclear transport
1.97 3.88e-06 GO:0016568 chromatin modification
2.55 5.66e-06 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.38 6.54e-06 GO:0006913 nucleocytoplasmic transport
1.30 1.87e-05 GO:0071842 cellular component organization at cellular level
1.36 4.75e-05 GO:0043412 macromolecule modification
1.74 4.94e-05 GO:0044265 cellular macromolecule catabolic process
1.67 8.24e-05 GO:0009057 macromolecule catabolic process
2.79 9.16e-05 GO:0031497 chromatin assembly
1.29 1.49e-04 GO:0044249 cellular biosynthetic process
2.45 1.69e-04 GO:0045333 cellular respiration
1.26 1.80e-04 GO:0019538 protein metabolic process
2.77 1.90e-04 GO:0006334 nucleosome assembly
2.63 2.89e-04 GO:0034728 nucleosome organization
2.63 4.35e-04 GO:0022904 respiratory electron transport chain
2.57 5.15e-04 GO:0065004 protein-DNA complex assembly
2.33 7.42e-04 GO:0006310 DNA recombination
2.49 7.79e-04 GO:0071824 protein-DNA complex subunit organization
1.33 8.35e-04 GO:0006464 protein modification process
1.27 9.39e-04 GO:0009058 biosynthetic process
3.54 1.12e-03 GO:0006413 translational initiation
1.07 1.12e-03 GO:0009987 cellular process
1.94 1.76e-03 GO:0034660 ncRNA metabolic process
1.75 2.01e-03 GO:0034622 cellular macromolecular complex assembly
1.50 2.46e-03 GO:0046907 intracellular transport
2.75 2.72e-03 GO:0000956 nuclear-transcribed mRNA catabolic process
1.21 3.39e-03 GO:0071840 cellular component organization or biogenesis
2.09 3.61e-03 GO:0034470 ncRNA processing
2.82 4.40e-03 GO:0006302 double-strand break repair
1.77 4.47e-03 GO:0051301 cell division
2.62 4.53e-03 GO:0006402 mRNA catabolic process
2.88 4.66e-03 GO:0031124 mRNA 3'-end processing
2.72 5.60e-03 GO:0006200 ATP catabolic process
1.45 6.49e-03 GO:0006351 transcription, DNA-dependent
3.08 7.16e-03 GO:0000723 telomere maintenance
2.41 8.79e-03 GO:0007059 chromosome segregation
3.02 1.05e-02 GO:0032200 telomere organization
1.75 1.24e-02 GO:0051325 interphase
2.74 1.26e-02 GO:0006368 transcription elongation from RNA polymerase II promoter
1.75 1.34e-02 GO:0006366 transcription from RNA polymerase II promoter
1.75 1.64e-02 GO:0070647 protein modification by small protein conjugation or removal
2.33 1.82e-02 GO:0006401 RNA catabolic process
1.37 2.01e-02 GO:0044248 cellular catabolic process
2.15 2.14e-02 GO:0022900 electron transport chain
1.99 2.31e-02 GO:0016570 histone modification
1.73 2.74e-02 GO:0051329 interphase of mitotic cell cycle
1.39 2.99e-02 GO:0032774 RNA biosynthetic process
1.96 3.25e-02 GO:0016569 covalent chromatin modification
1.25 3.81e-02 GO:0051252 regulation of RNA metabolic process
2.07 3.84e-02 GO:0000226 microtubule cytoskeleton organization
1.19 4.22e-02 GO:0016043 cellular component organization
1.94 4.52e-02 GO:0006260 DNA replication

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.49 6.90e-49 GO:0005634 nucleus
1.30 6.72e-45 GO:0043231 intracellular membrane-bounded organelle
1.30 1.65e-44 GO:0043227 membrane-bounded organelle
1.24 1.50e-37 GO:0043229 intracellular organelle
1.24 3.09e-37 GO:0043226 organelle
1.19 3.75e-37 GO:0044424 intracellular part
1.17 1.10e-34 GO:0005622 intracellular
1.73 1.70e-31 GO:0044428 nuclear part
1.73 4.25e-26 GO:0031981 nuclear lumen
1.64 5.01e-26 GO:0070013 intracellular organelle lumen
1.61 6.41e-25 GO:0031974 membrane-enclosed lumen
1.84 4.45e-24 GO:0005654 nucleoplasm
1.61 7.37e-24 GO:0043233 organelle lumen
1.46 2.92e-23 GO:0032991 macromolecular complex
1.32 2.07e-21 GO:0044446 intracellular organelle part
2.31 4.27e-21 GO:0005694 chromosome
1.31 6.62e-20 GO:0044422 organelle part
2.41 7.96e-20 GO:0044427 chromosomal part
2.55 5.79e-12 GO:0000785 chromatin
1.36 6.52e-11 GO:0043234 protein complex
1.96 2.39e-10 GO:0030529 ribonucleoprotein complex
1.54 4.59e-09 GO:0005739 mitochondrion
1.73 8.52e-09 GO:0044451 nucleoplasm part
1.32 2.15e-07 GO:0043228 non-membrane-bounded organelle
1.32 2.15e-07 GO:0043232 intracellular non-membrane-bounded organelle
2.72 4.36e-07 GO:0044455 mitochondrial membrane part
1.66 3.22e-06 GO:0044429 mitochondrial part
2.66 5.76e-05 GO:0032993 protein-DNA complex
2.04 1.05e-04 GO:0000228 nuclear chromosome
2.15 1.99e-04 GO:0044454 nuclear chromosome part
1.54 2.03e-04 GO:0031967 organelle envelope
1.52 4.66e-04 GO:0031975 envelope
1.04 4.85e-04 GO:0044464 cell part
1.04 5.10e-04 GO:0005623 cell
2.22 9.18e-04 GO:0000793 condensed chromosome
1.87 1.10e-03 GO:0005759 mitochondrial matrix
2.23 1.11e-03 GO:0000775 chromosome, centromeric region
2.90 1.24e-03 GO:0000786 nucleosome
2.19 2.53e-03 GO:0005681 spliceosomal complex
2.69 3.09e-03 GO:0070469 respiratory chain
2.75 3.39e-03 GO:0000922 spindle pole
2.17 5.64e-03 GO:0000151 ubiquitin ligase complex
1.70 6.52e-03 GO:0005815 microtubule organizing center
4.80 7.01e-03 GO:0005665 DNA-directed RNA polymerase II, core complex
1.93 9.48e-03 GO:0005819 spindle
2.67 9.54e-03 GO:0005746 mitochondrial respiratory chain
1.09 1.13e-02 GO:0005737 cytoplasm
2.33 1.33e-02 GO:0046930 pore complex
1.68 1.53e-02 GO:0005743 mitochondrial inner membrane
2.45 1.70e-02 GO:0005643 nuclear pore
1.78 2.13e-02 GO:0016604 nuclear body
1.22 3.08e-02 GO:0005829 cytosol
2.35 3.59e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.45 3.90e-02 GO:0000777 condensed chromosome kinetochore
1.76 4.22e-02 GO:0005813 centrosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.54 9.25e-26 GO:0003676 nucleic acid binding
1.89 9.06e-15 GO:0003723 RNA binding
1.46 6.63e-12 GO:0003677 DNA binding
1.40 1.86e-09 GO:0000166 nucleotide binding
1.15 6.45e-08 GO:0005515 protein binding
2.14 1.32e-04 GO:0003682 chromatin binding
1.37 1.43e-04 GO:0030554 adenyl nucleotide binding
1.37 1.47e-04 GO:0032559 adenyl ribonucleotide binding
1.37 1.62e-04 GO:0005524 ATP binding
1.17 2.26e-04 GO:0003824 catalytic activity
1.31 5.27e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.31 7.05e-04 GO:0032553 ribonucleotide binding
1.31 7.05e-04 GO:0032555 purine ribonucleotide binding
1.30 7.61e-04 GO:0017076 purine nucleotide binding
1.70 8.39e-04 GO:0016874 ligase activity
2.29 3.34e-03 GO:0016779 nucleotidyltransferase activity
1.06 3.67e-03 GO:0005488 binding
1.79 5.85e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.69 6.24e-03 GO:0016887 ATPase activity
1.84 7.12e-03 GO:0016881 acid-amino acid ligase activity
1.93 7.75e-03 GO:0043566 structure-specific DNA binding
1.63 9.10e-03 GO:0003712 transcription cofactor activity
1.62 1.01e-02 GO:0000988 protein binding transcription factor activity
1.62 1.01e-02 GO:0000989 transcription factor binding transcription factor activity
2.95 1.25e-02 GO:0003743 translation initiation factor activity
1.42 2.48e-02 GO:0016462 pyrophosphatase activity
3.03 2.75e-02 GO:0003899 DNA-directed RNA polymerase activity
3.03 2.75e-02 GO:0034062 RNA polymerase activity
1.41 2.86e-02 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
7.47 3.04e-02 GO:0017070 U6 snRNA binding
1.41 3.31e-02 GO:0016817 hydrolase activity, acting on acid anhydrides
2.45 3.75e-02 GO:0042393 histone binding