Motif ID: ZNF423.p2

Z-value: 1.226


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_484184180.243.7e-01Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_16530132 1.650 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr3_-_129024665 1.556 NM_001003794
MGLL
monoglyceride lipase
chr3_-_16529996 1.453 RFTN1
raftlin, lipid raft linker 1
chr1_+_26517032 1.335 CD52
CD52 molecule
chr1_+_26517045 1.276 CD52
CD52 molecule
chr19_+_14405100 1.098 NM_002741
PKN1
protein kinase N1
chr20_-_23014828 1.022 NM_012072
CD93
CD93 molecule
chr1_-_27825178 0.995 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr10_-_121286034 0.962 NM_002925
RGS10
regulator of G-protein signaling 10
chr17_+_73676219 0.926 NM_004710
SYNGR2
synaptogyrin 2
chr2_+_46623325 0.925 NM_012249
RHOQ
ras homolog gene family, member Q
chr19_-_54005916 0.876 NM_001164773
NM_001190
BCAT2

branched chain amino-acid transaminase 2, mitochondrial

chr2_+_46623396 0.868 RHOQ
ras homolog gene family, member Q
chr16_+_84490267 0.863 NM_002163
IRF8
interferon regulatory factor 8
chr19_-_46550788 0.857 TGFB1
transforming growth factor, beta 1
chr10_+_17310475 0.845 VIM
vimentin
chr1_+_26516967 0.842 NM_001803
CD52
CD52 molecule
chr22_+_35639564 0.836 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_-_32574185 0.828 NM_023009
MARCKSL1
MARCKS-like 1
chr9_+_92603920 0.825 SYK
spleen tyrosine kinase
chr16_+_55950195 0.815 NM_002990
CCL22
chemokine (C-C motif) ligand 22
chr18_-_5533967 0.779 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr9_+_92603884 0.769 SYK
spleen tyrosine kinase
chr9_+_92603894 0.721 SYK
spleen tyrosine kinase
chr19_+_14405216 0.703 PKN1
protein kinase N1
chr15_-_81667169 0.702 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr19_-_11550765 0.694 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr6_-_90119158 0.693 UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr3_+_52504391 0.684 NM_015136
STAB1
stabilin 1
chr16_+_23754860 0.668 PRKCB
protein kinase C, beta
chr19_-_10311262 0.664 NM_002162
ICAM3
intercellular adhesion molecule 3
chr1_-_183210296 0.662 NM_052966
FAM129A
family with sequence similarity 129, member A
chr1_-_183210155 0.659 FAM129A
family with sequence similarity 129, member A
chr10_+_17311347 0.644 VIM
vimentin
chr16_+_23754772 0.637 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr1_-_210939820 0.637 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr3_+_52504410 0.635 STAB1
stabilin 1
chr10_+_17311307 0.630 VIM
vimentin
chr3_-_129023850 0.623 NM_007283
MGLL
monoglyceride lipase
chr19_+_49943773 0.616 NM_005178
BCL3
B-cell CLL/lymphoma 3
chr6_-_90119068 0.613 UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr2_+_48610796 0.605 NM_001198595
NM_006873
STON1

stonin 1

chr8_+_17478214 0.595 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr10_+_3099708 0.591 NM_002627
PFKP
phosphofructokinase, platelet
chr20_-_57015547 0.590 CTSZ
cathepsin Z
chr9_-_16860719 0.574 NM_017637
BNC2
basonuclin 2
chr13_-_109757442 0.558 NM_001845
COL4A1
collagen, type IV, alpha 1
chr6_+_33352886 0.557 NM_003782
B3GALT4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr9_-_16860664 0.554 BNC2
basonuclin 2
chr11_-_66877519 0.549 NM_021173
POLD4
polymerase (DNA-directed), delta 4
chr20_-_57015698 0.545 NM_001336
CTSZ
cathepsin Z
chr9_+_111582317 0.531 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr20_+_30103642 0.531 NM_001172129
NM_001172130
NM_001172131
NM_001172132
NM_001172133
NM_002110
HCK





hemopoietic cell kinase





chrX_+_152413646 0.527 BGN
biglycan
chr16_+_23754822 0.525 PRKCB
protein kinase C, beta
chr22_+_21116283 0.515


chr1_-_210939929 0.513 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr7_+_26158257 0.512 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr19_-_11550576 0.511 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chrX_+_152413540 0.499 NM_001711
BGN
biglycan
chr3_+_49002774 0.496 P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr21_+_25933637 0.495 JAM2
junctional adhesion molecule 2
chr20_-_43972949 0.492 PLTP
phospholipid transfer protein
chr9_-_134219950 0.486 SETX
senataxin
chr9_+_99303639 0.472 NM_003275
TMOD1
tropomodulin 1
chr1_-_210939727 0.471


chr9_-_134220179 0.468 NM_015046
SETX
senataxin
chr16_+_2807164 0.466 NM_006799
NM_144956
NM_144957
PRSS21


protease, serine, 21 (testisin)


chr9_+_92604025 0.461 NM_001174168
SYK
spleen tyrosine kinase
chr20_-_43972982 0.461 PLTP
phospholipid transfer protein
chr1_-_9052253 0.458 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chrX_-_101658297 0.456 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr5_+_118434966 0.456 NM_005509
DMXL1
Dmx-like 1
chr1_+_99502655 0.455 LPPR4
lipid phosphate phosphatase-related protein type 4
chr1_+_110031940 0.453 NM_000561
NM_146421
GSTM1

glutathione S-transferase mu 1

chr10_+_17311282 0.449 VIM
vimentin
chr8_-_70908130 0.443 NM_001146008
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr2_+_74629654 0.443 NM_001197260
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr5_+_153550463 0.442 NM_198321
GALNT10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr21_+_25933916 0.438 JAM2
junctional adhesion molecule 2
chr10_+_17311242 0.435 VIM
vimentin
chr19_-_23733411 0.429 NM_138286
ZNF681
zinc finger protein 681
chr5_-_136862786 0.420 NM_004598
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr1_+_75962959 0.417 ACADM
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chr11_+_1848674 0.411 NM_001013254
NM_001013255
LSP1

lymphocyte-specific protein 1

chr21_+_25933938 0.407 JAM2
junctional adhesion molecule 2
chr16_+_57055717 0.398 NDRG4
NDRG family member 4
chr11_+_61352209 0.397 NM_004265
FADS2
fatty acid desaturase 2
chr19_-_53365371 0.397 NM_000234
LIG1
ligase I, DNA, ATP-dependent
chr6_+_43005126 0.396 CNPY3
canopy 3 homolog (zebrafish)
chr10_+_17311283 0.393 VIM
vimentin
chr11_-_47557034 0.387 NM_016506
NM_018095
KBTBD4

kelch repeat and BTB (POZ) domain containing 4

chr12_+_111829191 0.384 OAS1
2',5'-oligoadenylate synthetase 1, 40/46kDa
chr3_-_52906381 0.378 TMEM110
transmembrane protein 110
chrX_-_118711088 0.378 SEPT6
septin 6
chr12_+_63504618 0.369 NM_015279
TBC1D30
TBC1 domain family, member 30
chr16_+_2807228 0.368 PRSS21
protease, serine, 21 (testisin)
chr3_+_115040369 0.363 NM_017577
GRAMD1C
GRAM domain containing 1C
chr6_+_43005214 0.360 CNPY3
canopy 3 homolog (zebrafish)
chr7_+_2409731 0.360 NM_018641
CHST12
carbohydrate (chondroitin 4) sulfotransferase 12
chrX_+_48915127 0.358 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr12_+_111829121 0.357 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chrX_-_1532648 0.355 NM_001173473
ASMTL
acetylserotonin O-methyltransferase-like
chrY_-_1532648 0.355 NM_001173473
ASMTL
acetylserotonin O-methyltransferase-like
chr11_+_61352348 0.353 FADS2
fatty acid desaturase 2
chr7_+_73262283 0.352 LAT2
linker for activation of T cells family, member 2
chr6_-_32268267 0.349 GPSM3
G-protein signaling modulator 3
chr1_+_32889335 0.348 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr1_+_75963030 0.347 ACADM
acyl-CoA dehydrogenase, C-4 to C-12 straight chain
chr7_-_1562272 0.345 NM_001097620
TMEM184A
transmembrane protein 184A
chr9_-_134220161 0.345 SETX
senataxin
chr6_+_31651319 0.344 NM_000594
TNF
tumor necrosis factor
chr6_+_43004837 0.342 NM_006586
CNPY3
canopy 3 homolog (zebrafish)
chr10_+_29738513 0.335 LOC387647
patched domain containing 3 pseudogene
chr4_+_148872902 0.332 NM_024605
ARHGAP10
Rho GTPase activating protein 10
chr15_+_88732453 0.332 IQGAP1
IQ motif containing GTPase activating protein 1
chr9_+_125813672 0.324 NM_004789
LHX2
LIM homeobox 2
chr7_-_50828159 0.322 GRB10
growth factor receptor-bound protein 10
chr19_-_40928131 0.321 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr5_+_141283647 0.319 KIAA0141
KIAA0141
chr1_+_110000396 0.319 GSTM2
GSTM4
glutathione S-transferase mu 2 (muscle)
glutathione S-transferase mu 4
chr1_-_180840016 0.315 NM_002928
RGS16
regulator of G-protein signaling 16
chr3_+_32701663 0.313 NM_015442
CNOT10
CCR4-NOT transcription complex, subunit 10
chr11_-_44928803 0.312 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr6_+_89848229 0.312 PNRC1
proline-rich nuclear receptor coactivator 1
chr22_+_21065134 0.305 LOC100290481
immunoglobulin lambda light chain-like
chr16_-_55016872 0.304 NM_001144
AMFR
autocrine motility factor receptor
chr12_+_58276114 0.303 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chrX_+_64804235 0.302 NM_002444
MSN
moesin
chr1_-_181826086 0.302 NCF2
neutrophil cytosolic factor 2
chr3_-_69212192 0.301 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr6_-_18372617 0.297 NM_001134709
NM_003472
DEK

DEK oncogene

chr22_+_35586950 0.294 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr10_+_135190855 0.291 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr6_+_31538934 0.291 NM_006674
HCP5
HLA complex P5
chr11_+_116555048 0.278 NM_001040455
SIDT2
SID1 transmembrane family, member 2
chr19_-_1993022 0.277 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr10_+_124904269 0.277 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr5_+_43638495 0.277 NM_012343
NNT
nicotinamide nucleotide transhydrogenase
chr5_+_141283550 0.276 NM_001142603
NM_014773
KIAA0141

KIAA0141

chr4_-_149582948 0.275 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr13_+_109757593 0.275 NM_001846
COL4A2
collagen, type IV, alpha 2
chr19_-_18409971 0.275 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr13_-_94751573 0.274 NM_001105515
NM_005845
ABCC4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr19_-_18409788 0.273 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr21_+_44377974 0.273 C21orf33
chromosome 21 open reading frame 33
chr1_-_149566446 0.270 PI4KB
phosphatidylinositol 4-kinase, catalytic, beta
chr1_-_33139425 0.268 NM_033504
TMEM54
transmembrane protein 54
chr14_+_66044958 0.267 GPHN
gephyrin
chr22_+_38183262 0.267 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr9_+_100609754 0.267 NM_024642
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr17_-_23244499 0.266 NM_001076680
C17orf108
chromosome 17 open reading frame 108
chr2_+_65136989 0.264 NM_015147
CEP68
centrosomal protein 68kDa
chr5_+_121675284 0.262 SNCAIP
synuclein, alpha interacting protein
chr1_+_32438788 0.260 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr6_+_237033 0.259 NM_020185
DUSP22
dual specificity phosphatase 22
chr19_-_12638540 0.259 NM_000528
NM_001173498
MAN2B1

mannosidase, alpha, class 2B, member 1

chr16_-_1761504 0.258 NME3
non-metastatic cells 3, protein expressed in
chr10_+_135042684 0.256 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr9_-_129782624 0.256 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr17_-_7531456 0.256 NM_000546
NM_001126112
NM_001126113
NM_001126114
TP53



tumor protein p53



chr22_+_29333069 0.254 NM_000355
NM_001184726
TCN2

transcobalamin II

chr11_-_61316628 0.253 NM_014206
C11orf10
chromosome 11 open reading frame 10
chr15_+_88732474 0.252 NM_003870
IQGAP1
IQ motif containing GTPase activating protein 1
chr14_+_91859904 0.252 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr9_+_4975243 0.252 NM_004972
JAK2
Janus kinase 2
chr1_-_154290112 0.251 NM_020131
UBQLN4
ubiquilin 4
chr17_-_70662088 0.251 HN1
hematological and neurological expressed 1
chr1_-_204852465 0.251 NM_006893
EIF2D
eukaryotic translation initiation factor 2D
chr17_-_37681917 0.250 NM_012448
STAT5B
signal transducer and activator of transcription 5B
chr1_+_10381671 0.250 NM_002631
PGD
phosphogluconate dehydrogenase
chr1_-_204852317 0.250 EIF2D
eukaryotic translation initiation factor 2D
chr18_+_75261231 0.246 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr18_+_71051713 0.246 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr11_-_47556785 0.246 KBTBD4
kelch repeat and BTB (POZ) domain containing 4
chr11_+_64631919 0.243 C11orf2
chromosome 11 open reading frame 2
chr7_+_142695511 0.242 NM_032982
NM_032983
CASP2

caspase 2, apoptosis-related cysteine peptidase

chr3_-_52542849 0.241 NT5DC2
5'-nucleotidase domain containing 2
chr15_+_88732493 0.240 IQGAP1
IQ motif containing GTPase activating protein 1
chr15_-_81113676 0.238 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr11_+_46359855 0.237 MDK
midkine (neurite growth-promoting factor 2)
chr3_+_5204357 0.237 NM_014674
EDEM1
ER degradation enhancer, mannosidase alpha-like 1
chr11_+_46359836 0.237 MDK
midkine (neurite growth-promoting factor 2)
chr3_-_52542748 0.236 NM_001134231
NT5DC2
5'-nucleotidase domain containing 2
chr10_-_74925724 0.236 PPP3CB
protein phosphatase 3, catalytic subunit, beta isozyme
chr14_-_91657818 0.236 NM_004545
NDUFB1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa
chr19_+_51796399 0.235 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr8_+_142207866 0.234 NM_014957
DENND3
DENN/MADD domain containing 3
chr19_-_6542012 0.234 CD70
CD70 molecule
chr15_-_57013058 0.233 SLTM
SAFB-like, transcription modulator
chr22_+_21065207 0.233 IGLJ3
immunoglobulin lambda joining 3
chr17_-_55958073 0.230 APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr11_-_6589754 0.230 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr17_-_74432800 0.229 TIMP2
TIMP metallopeptidase inhibitor 2
chr19_-_6542082 0.229 CD70
CD70 molecule
chr11_+_46359878 0.228 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr17_-_74433048 0.227 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr19_+_19872700 0.226 NM_031218
ZNF93
zinc finger protein 93
chr17_-_10042579 0.225 NM_201433
GAS7
growth arrest-specific 7
chr19_-_6542136 0.224 NM_001252
CD70
CD70 molecule

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.17 5.38e-04 GO:0050789 regulation of biological process
1.16 9.51e-04 GO:0065007 biological regulation
1.16 6.92e-03 GO:0050794 regulation of cellular process
1.31 2.96e-02 GO:0048519 negative regulation of biological process

Nothing significant found in compartment category.

Nothing significant found in function category.