Motif ID: POU6F1.p2

Z-value: 1.127


Transcription factors associated with POU6F1.p2:

Gene SymbolEntrez IDGene Name
POU6F1 5463 POU class 6 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU6F1chr12_-_49878216-0.562.3e-02Click!


Activity profile for motif POU6F1.p2.

activity profile for motif POU6F1.p2


Sorted Z-values histogram for motif POU6F1.p2

Sorted Z-values for motif POU6F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_49996353 3.595 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr5_+_125786717 2.882 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr1_+_151270301 2.560 NM_003125
SPRR1B
small proline-rich protein 1B
chr5_+_125786975 2.530 GRAMD3
GRAM domain containing 3
chr10_+_4995685 2.297 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr10_+_4995453 2.191 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr18_+_59295123 1.964 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr3_-_112796855 1.752 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr11_+_69176391 1.643 CCND1
cyclin D1
chr13_-_43908994 1.545 TSC22D1
TSC22 domain family, member 1
chr13_-_43908985 1.467 TSC22D1
TSC22 domain family, member 1
chr13_-_43908937 1.462 TSC22D1
TSC22 domain family, member 1
chr10_+_4995597 1.458 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr13_-_43908995 1.412 TSC22D1
TSC22 domain family, member 1
chr13_-_43908972 1.331 NM_006022
TSC22D1
TSC22 domain family, member 1
chr10_-_5035967 1.277 NM_001135241
AKR1C1
AKR1C2
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr12_-_28016182 1.061 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr6_-_47362102 1.023 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chrX_+_65299157 0.997 NM_138737
HEPH
hephaestin
chr1_-_116112853 0.842 CASQ2
calsequestrin 2 (cardiac muscle)
chr1_-_116112921 0.829 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr1_-_191422346 0.829 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_-_116112684 0.770 CASQ2
calsequestrin 2 (cardiac muscle)
chr3_+_143858428 0.770 NM_001172312
PLS1
plastin 1
chrX_+_135058402 0.715 NM_001159700
FHL1
four and a half LIM domains 1
chr2_-_215949566 0.694 FN1
fibronectin 1
chrX_+_135106578 0.682 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr6_-_136888771 0.672 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr1_+_15145001 0.649 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr6_-_47361921 0.624 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr3_-_124821868 0.610 MYLK
myosin light chain kinase
chr12_+_54611212 0.600 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr22_-_34566276 0.580 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr22_-_34566367 0.579 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chrX_-_13744933 0.577 GPM6B
glycoprotein M6B
chr2_-_158439868 0.557 NM_001105
ACVR1
activin A receptor, type I
chr22_-_34566210 0.545 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_107569256 0.539 NM_001847
COL4A6
collagen, type IV, alpha 6
chr5_+_125723686 0.522 NM_001146319
GRAMD3
GRAM domain containing 3
chr18_+_27281729 0.505 NM_001944
DSG3
desmoglein 3
chr17_-_46479127 0.502 SPAG9
sperm associated antigen 9
chr4_-_145281237 0.497 NM_002099
GYPA
glycophorin A (MNS blood group)
chr7_+_133862883 0.487 NM_020299
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr17_-_10265991 0.482 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr12_-_88573949 0.466 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr11_-_59390518 0.424 NM_001062
TCN1
transcobalamin I (vitamin B12 binding protein, R binder family)
chr6_-_47385470 0.419 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chrX_+_146941222 0.386 FTH1P8
ferritin, heavy polypeptide 1 pseudogene 8
chrX_+_65299352 0.371 HEPH
hephaestin
chr9_-_133944877 0.370 MED27
mediator complex subunit 27
chr20_+_9146036 0.355 NM_182797
PLCB4
phospholipase C, beta 4
chr1_+_194887630 0.328 NM_000186
NM_001014975
CFH

complement factor H

chr11_-_11331411 0.318 CSNK2A1P
casein kinase 2, alpha 1 polypeptide pseudogene
chr13_+_77007809 0.312 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr17_-_36232366 0.305 NM_000421
KRT10
keratin 10
chr9_-_94206648 0.302 NM_014057
NM_033014
OGN

osteoglycin

chr6_-_2785682 0.299 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr7_+_134114912 0.285 CALD1
caldesmon 1
chr6_-_47385605 0.284 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr3_-_124822113 0.279 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr3_+_160269734 0.279 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr18_+_45342398 0.279 NM_006033
LIPG
lipase, endothelial
chr2_-_1905508 0.278 MYT1L
myelin transcription factor 1-like
chr16_-_69392568 0.275 VAC14
Vac14 homolog (S. cerevisiae)
chr7_+_134114957 0.270 CALD1
caldesmon 1
chrX_+_150635162 0.270 NM_033085
FATE1
fetal and adult testis expressed 1
chr8_+_67505091 0.267 RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr16_-_69392561 0.266 NM_018052
VAC14
Vac14 homolog (S. cerevisiae)
chr15_+_49988882 0.266 TMOD3
tropomodulin 3 (ubiquitous)
chr9_-_94338072 0.260 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr15_+_72209795 0.258 NM_020851
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr15_+_72209973 0.255 ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr7_-_83662152 0.255 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr21_-_35343456 0.255 NM_001754
RUNX1
runt-related transcription factor 1
chr1_+_26376560 0.255 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr2_+_73911477 0.254 STAMBP
STAM binding protein
chr12_-_44919818 0.253 SLC38A1
solute carrier family 38, member 1
chr6_+_131508153 0.252 NM_016377
AKAP7
A kinase (PRKA) anchor protein 7
chr16_-_69392562 0.251 VAC14
Vac14 homolog (S. cerevisiae)
chr12_-_69434330 0.250 PTPRR
protein tyrosine phosphatase, receptor type, R
chr5_+_140200995 0.245 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr17_-_53847937 0.230 RNF43
ring finger protein 43
chr7_+_138469029 0.222 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr7_-_41709191 0.221 NM_002192
INHBA
inhibin, beta A
chr15_+_47502666 0.215 NM_002009
FGF7
fibroblast growth factor 7
chr4_-_145159889 0.214 NM_002100
GYPB
glycophorin B (MNS blood group)
chr1_-_108588186 0.209 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chr19_-_14750347 0.206 NM_013447
NM_152916
NM_152917
NM_152918
NM_152919
NM_152920
NM_152921
EMR2






egf-like module containing, mucin-like, hormone receptor-like 2






chr3_-_121117647 0.200 GSK3B
glycogen synthase kinase 3 beta
chr4_+_41309668 0.199 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr4_+_146250978 0.198 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr21_-_35343500 0.195 RUNX1
runt-related transcription factor 1
chrX_-_102828238 0.194 NM_001142418
NM_001142423
NM_001142424
NM_001142425
NM_001142426
NM_001142429
NM_001142430
NM_012286
MORF4L2







mortality factor 4 like 2







chr1_+_149299307 0.192 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_100776280 0.191 NM_022049
GPR88
G protein-coupled receptor 88
chrX_-_55074125 0.188 NM_000032
NM_001037967
NM_001037968
ALAS2


aminolevulinate, delta-, synthase 2


chr1_-_201321711 0.184 MYOG
myogenin (myogenic factor 4)
chr1_-_93030538 0.178 NM_005665
EVI5
ecotropic viral integration site 5
chr2_-_55090759 0.174 NM_007008
RTN4
reticulon 4
chr2_-_200033445 0.174 SATB2
SATB homeobox 2
chr21_-_26269298 0.170 APP
amyloid beta (A4) precursor protein
chr8_-_59575249 0.169 NM_000780
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr16_-_32595553 0.168 NM_016212
TP53TG3
TP53 target 3
chr4_+_70896236 0.167 NM_001009181
NM_003154
STATH

statherin

chr2_-_105421661 0.166 NM_201557
FHL2
four and a half LIM domains 2
chr12_+_1596482 0.164 NM_030775
WNT5B
wingless-type MMTV integration site family, member 5B
chr17_-_64752550 0.162 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr5_+_140583098 0.160 NM_018934
PCDHB14
protocadherin beta 14
chr5_+_140509803 0.159 NM_018939
PCDHB6
protocadherin beta 6
chr16_-_69392385 0.158 VAC14
Vac14 homolog (S. cerevisiae)
chr12_-_69434650 0.157 PTPRR
protein tyrosine phosphatase, receptor type, R
chr12_-_102967828 0.154 GLT8D2
glycosyltransferase 8 domain containing 2
chr20_+_62266270 0.152 NM_004535
MYT1
myelin transcription factor 1
chr11_-_83071084 0.152 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_139960874 0.152 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr16_+_33112480 0.150 NM_016212
TP53TG3
TP53 target 3
chr12_-_69434598 0.149 NM_130846
PTPRR
protein tyrosine phosphatase, receptor type, R
chr2_+_183290912 0.149 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr16_-_69392545 0.147 VAC14
Vac14 homolog (S. cerevisiae)
chr8_+_32698892 0.146 NM_001159996
NRG1
neuregulin 1
chr3_+_129927714 0.143 RAB7A
RAB7A, member RAS oncogene family
chrX_-_153698930 0.141 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr1_+_213245507 0.137 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr16_+_33169015 0.135 NM_016212
TP53TG3
TP53 target 3
chr17_+_46176105 0.134 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr7_+_120490054 0.133 C7orf58
chromosome 7 open reading frame 58
chr16_-_57309625 0.133 GOT2
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
chrX_-_33139349 0.131 NM_004006
DMD
dystrophin
chr3_-_187309442 0.130 NM_004454
ETV5
ets variant 5
chr9_-_133945064 0.129 NM_004269
CRSP8P
MED27
mediator complex subunit 27 pseudogene
mediator complex subunit 27
chr21_-_35153664 0.129 RUNX1
runt-related transcription factor 1
chr4_-_145046109 0.128 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chrX_+_123062143 0.128 STAG2
stromal antigen 2
chr3_+_129927716 0.128 RAB7A
RAB7A, member RAS oncogene family
chr11_+_112337199 0.126 NM_000615
NM_001076682
NM_181351
NCAM1


neural cell adhesion molecule 1


chr2_+_201806410 0.124 NM_001080124
NM_001228
NM_033355
NM_033358
CASP8



caspase 8, apoptosis-related cysteine peptidase



chr7_+_94135384 0.121 PEG10
paternally expressed 10
chr1_-_245120900 0.121 AHCTF1
AT hook containing transcription factor 1
chr17_-_36346240 0.121 KRT23
keratin 23 (histone deacetylase inducible)
chr9_+_21399132 0.121 NM_002170
IFNA8
interferon, alpha 8
chr10_+_102097246 0.120


chr3_+_190831909 0.118 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr7_+_93373755 0.118 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr14_-_64479198 0.117 NM_002083
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr10_-_61819493 0.117 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chrX_-_52752935 0.116 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chr1_-_178100204 0.115


chr6_-_49942147 0.115 NM_001131
NM_170609
CRISP1

cysteine-rich secretory protein 1

chr3_+_70068440 0.115 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr8_+_54926920 0.114 NM_170587
RGS20
regulator of G-protein signaling 20
chr6_+_152053323 0.112 NM_001122742
ESR1
estrogen receptor 1
chr7_-_50596238 0.110 NM_000790
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr7_-_63660879 0.110


chr4_+_95595419 0.109 PDLIM5
PDZ and LIM domain 5
chr15_+_38296920 0.109 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chrX_+_55760774 0.109 NM_006064
NM_016656
RRAGB

Ras-related GTP binding B

chr2_+_166034402 0.108 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chrX_+_77889861 0.107 NM_005296
LPAR4
lysophosphatidic acid receptor 4
chr16_+_4842077 0.107 NM_016936
UBN1
ubinuclein 1
chr16_-_31347151 0.105 NM_005205
COX6A2
cytochrome c oxidase subunit VIa polypeptide 2
chr12_-_16652202 0.104 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr10_-_29794484 0.104 SVIL
supervillin
chr1_+_149299490 0.103 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr4_+_107456215 0.102 NM_001142415
NM_004757
AIMP1

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

chrX_+_46935035 0.099 NM_153280
UBA1
ubiquitin-like modifier activating enzyme 1
chr6_+_155579788 0.099 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr3_+_129927723 0.098 RAB7A
RAB7A, member RAS oncogene family
chr6_+_29187565 0.097 NM_001005216
OR2J3
olfactory receptor, family 2, subfamily J, member 3
chr3_+_129927668 0.097 NM_004637
RAB7A
RAB7A, member RAS oncogene family
chr10_+_96433240 0.096 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr9_-_21177529 0.095 NM_021068
IFNA4
interferon, alpha 4
chr2_+_201464884 0.094 NM_001142356
NIF3L1
NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr17_-_7159389 0.089 GPS2
G protein pathway suppressor 2
chr21_-_35343448 0.089 RUNX1
runt-related transcription factor 1
chr1_-_56750235 0.088 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_93172119 0.088


chr1_-_116184846 0.088 NM_001111061
NHLH2
nescient helix loop helix 2
chr12_-_47250069 0.088 NM_002289
LALBA
lactalbumin, alpha-
chr8_-_91164100 0.087 NM_004929
CALB1
calbindin 1, 28kDa
chr15_+_49909147 0.084 TMOD3
tropomodulin 3 (ubiquitous)
chr8_+_1980564 0.083 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr11_-_27637771 0.083 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr7_-_38279757 0.082 NM_001003799
NM_001003806
TARP

TRGV9
TCR gamma alternate reading frame protein

T cell receptor gamma variable 9
chr5_+_147423727 0.081 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr18_+_8707368 0.080 NM_015210
KIAA0802
KIAA0802
chr4_-_69116839 0.080 NM_001077
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr3_+_46894239 0.079 NM_000316
PTH1R
parathyroid hormone 1 receptor
chrX_+_46938178 0.079 UBA1
ubiquitin-like modifier activating enzyme 1
chr3_+_161040439 0.079 SCHIP1
schwannomin interacting protein 1
chr2_+_234191029 0.078 NM_019076
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr16_+_1668257 0.078 NM_144570
HN1L
hematological and neurological expressed 1-like
chr2_+_166137091 0.077 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr3_+_161040343 0.076 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr3_-_121065112 0.076


chrX_+_21960841 0.076 NM_000444
PHEX
phosphate regulating endopeptidase homolog, X-linked
chrM_+_4465 0.076


chr3_-_152403636 0.075 NM_013308
GPR171
G protein-coupled receptor 171
chr5_+_140235114 0.074 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr5_+_140552087 0.073 NM_018930
PCDHB10
protocadherin beta 10
chr19_-_21742162 0.072 NM_173531
ZNF100
zinc finger protein 100

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.48 9.87e-05 GO:0007156 homophilic cell adhesion
2.41 4.40e-04 GO:0009888 tissue development
14.95 1.92e-03 GO:0008038 neuron recognition
1.41 2.33e-03 GO:0032501 multicellular organismal process
24.20 1.20e-02 GO:0007413 axonal fasciculation
7.21 1.44e-02 GO:0008037 cell recognition
3.11 2.28e-02 GO:0016337 cell-cell adhesion
1.54 2.45e-02 GO:0048731 system development
1.49 3.85e-02 GO:0048856 anatomical structure development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.51 2.26e-04 GO:0005886 plasma membrane
1.51 2.53e-04 GO:0071944 cell periphery
1.55 2.19e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

enrichment   p-value GO term description
42.35 3.51e-03 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
31.76 1.38e-02 GO:0047023 androsterone dehydrogenase activity
2.47 3.17e-02 GO:0004930 G-protein coupled receptor activity
1.77 3.22e-02 GO:0004872 receptor activity
2.16 3.54e-02 GO:0005509 calcium ion binding