Motif ID: FOXO1,3,4.p2

Z-value: 1.554


Transcription factors associated with FOXO1,3,4.p2:

Gene SymbolEntrez IDGene Name
FOXO1 2308 forkhead box O1
FOXO3 2309 forkhead box O3
FOXO4 4303 forkhead box O4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXO3chr6_+_1089877030.702.3e-03Click!
FOXO1chr13_-_40138607-0.312.5e-01Click!
FOXO4chrX_+_70232362-0.263.3e-01Click!


Activity profile for motif FOXO1,3,4.p2.

activity profile for motif FOXO1,3,4.p2


Sorted Z-values histogram for motif FOXO1,3,4.p2

Sorted Z-values for motif FOXO1,3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXO1,3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_150569574 7.183 TM4SF1
transmembrane 4 L six family member 1
chr1_-_56817823 4.533 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr9_+_74956614 4.076 ANXA1
annexin A1
chr7_+_134114957 3.784 CALD1
caldesmon 1
chr16_+_54070302 3.738 NM_004530
 MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr4_+_26194643 3.683 NM_018317
 TBC1D19
TBC1 domain family, member 19
chr1_-_56817802 3.489 PPAP2B
phosphatidic acid phosphatase type 2B
chr4_-_81213207 3.243


chr1_-_56817568 3.060 PPAP2B
phosphatidic acid phosphatase type 2B
chr22_+_31526801 2.811 NM_000362
 TIMP3
TIMP metallopeptidase inhibitor 3
chr1_-_56817717 2.682 PPAP2B
phosphatidic acid phosphatase type 2B
chr18_-_20106187 2.593 NM_018030
 OSBPL1A
oxysterol binding protein-like 1A
chr9_+_74956601 2.532 ANXA1
annexin A1
chr8_+_70567634 2.515 SULF1
sulfatase 1
chr3_+_62280435 2.421 NM_020685
 C3orf14
chromosome 3 open reading frame 14
chr10_-_90740935 2.392 NM_001141945
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr12_+_51777715 2.374 IGFBP6
insulin-like growth factor binding protein 6
chr6_+_121798443 2.339 NM_000165
 GJA1
gap junction protein, alpha 1, 43kDa
chr4_+_54790020 2.329 NM_006206
 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr12_+_51777684 2.296 NM_002178
 IGFBP6
insulin-like growth factor binding protein 6

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.75 6.07e-03 GO:0044420 extracellular matrix part
2.04 5.05e-03 GO:0005578 proteinaceous extracellular matrix
1.82 4.14e-02 GO:0031012 extracellular matrix
1.46 3.18e-02 GO:0044421 extracellular region part
1.40 1.55e-03 GO:0005576 extracellular region
1.21 4.02e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
12.84 2.00e-02 GO:0047023 androsterone dehydrogenase activity
2.54 4.72e-02 GO:0019838 growth factor binding
1.62 2.88e-02 GO:0005509 calcium ion binding