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• Activity deltas table
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Motif ID: ATF4.p2

Z-value: 1.196

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_-_140270749	1.721	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr19_+_18145578	1.611	NM_006332	IFI30	interferon, gamma-inducible protein 30
chr19_+_18145631	1.600		IFI30	interferon, gamma-inducible protein 30
chr11_+_67107852	1.437		GSTP1	glutathione S-transferase pi 1
chr4_+_75529716	1.394	NM_001657	AREG	amphiregulin
chr16_+_22732982	1.379		HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr7_-_105712565	1.368		NAMPT	nicotinamide phosphoribosyltransferase
chr1_+_26368969	1.362	NM_015871	ZNF593	zinc finger protein 593
chr4_+_75699652	1.361	NM_001657	AREG	amphiregulin
chr7_+_5598964	1.344		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr12_+_131194967	1.313		NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)
chr17_+_54124928	1.309		RAD51C	RAD51 homolog C (S. cerevisiae)
chr17_-_8092098	1.259	NM_025099	CTC1	CTS telomere maintenance complex component 1
chr17_+_54124952	1.221	NM_002876 NM_058216	RAD51C	RAD51 homolog C (S. cerevisiae)
chr11_+_4072635	1.182		RRM1	ribonucleotide reductase M1
chr11_+_4072653	1.154		RRM1	ribonucleotide reductase M1
chr18_+_18767275	1.143	NM_002894	RBBP8	retinoblastoma binding protein 8
chr19_-_60610971	1.124		UBE2S	ubiquitin-conjugating enzyme E2S
chr11_+_4072499	1.120	NM_001033	RRM1	ribonucleotide reductase M1
chr18_+_55718171	1.113	NM_021127	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1
chr11_+_3775529	1.097	NM_001145438	PGAP2	post-GPI attachment to proteins 2
chr12_+_131194931	1.079	NM_024078	NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)
chr19_+_10223852	1.068		MRPL4	mitochondrial ribosomal protein L4
chr11_-_3775547	1.060	NM_005387 NM_016320 NM_139131 NM_139132	NUP98	nucleoporin 98kDa
chr5_+_5475766	1.043
chr7_+_5598979	1.037	NM_003088	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_-_148818701	1.010		MCL1	myeloid cell leukemia sequence 1 (BCL2-related)
chr3_-_33734544	1.004		CLASP2	cytoplasmic linker associated protein 2
chr6_-_31882704	0.988	NM_021177	LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr16_-_3707450	0.987	NM_016292	TRAP1	TNF receptor-associated protein 1
chr7_+_116447499	0.969		ST7	suppression of tumorigenicity 7
chr1_-_52642646	0.953	NM_001190818 NM_001190819 NM_004153	ORC1	origin recognition complex, subunit 1
chr6_-_31882558	0.948		LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr17_-_8092078	0.928		CTC1	CTS telomere maintenance complex component 1
chr18_+_9698299	0.927		RAB31	RAB31, member RAS oncogene family
chr14_+_67156386	0.923		ARG2	arginase, type II
chr4_-_122964232	0.921		CCNA2	cyclin A2
chr19_-_60610792	0.912		UBE2S	ubiquitin-conjugating enzyme E2S
chr6_-_106880229	0.910		ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)
chr6_-_34772565	0.901	NM_022758 NM_024294	C6orf106	chromosome 6 open reading frame 106
chr2_+_74610751	0.885		HTRA2	HtrA serine peptidase 2
chr8_+_26204960	0.880		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr6_-_106880182	0.880		ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)
chr6_+_12825818	0.875	NM_030948	PHACTR1	phosphatase and actin regulator 1
chr1_+_51855343	0.872		OSBPL9	oxysterol binding protein-like 9
chr7_-_105712646	0.851	NM_005746	NAMPT	nicotinamide phosphoribosyltransferase
chr1_+_91739241	0.828	NM_001134420	CDC7	cell division cycle 7 homolog (S. cerevisiae)
chr16_+_22733307	0.812	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr7_-_124357272	0.807	NM_001042594 NM_015450	POT1	protection of telomeres 1 homolog (S. pombe)
chr7_-_73306629	0.799		RFC2	replication factor C (activator 1) 2, 40kDa
chr11_+_117362272	0.794	NM_001558	IL10RA	interleukin 10 receptor, alpha
chr11_-_28086277	0.791	NM_031217	KIF18A	kinesin family member 18A
chr5_+_112877251	0.791	NM_022828	YTHDC2	YTH domain containing 2
chr10_+_22674379	0.789	NM_012443 NM_172242	SPAG6	sperm associated antigen 6
chr11_-_28086263	0.772		KIF18A	kinesin family member 18A
chr3_+_186786655	0.763	NM_021627	SENP2	SUMO1/sentrin/SMT3 specific peptidase 2
chr7_-_73306668	0.762	NM_002914 NM_181471	RFC2	replication factor C (activator 1) 2, 40kDa
chr14_-_54563520	0.762		WDHD1	WD repeat and HMG-box DNA binding protein 1
chr3_-_151963577	0.748		SIAH2	seven in absentia homolog 2 (Drosophila)
chr17_+_24095135	0.747	NM_004295	TRAF4	TNF receptor-associated factor 4
chr4_-_122964428	0.746	NM_001237	CCNA2	cyclin A2
chr5_-_1935764	0.744	NM_016358	IRX4	iroquois homeobox 4
chr19_+_10223912	0.742		MRPL4	mitochondrial ribosomal protein L4
chr19_+_4353658	0.741	NM_005483	CHAF1A	chromatin assembly factor 1, subunit A (p150)
chr7_+_107318821	0.730	NM_000108	DLD	dihydrolipoamide dehydrogenase
chr19_+_10223886	0.722		MRPL4	mitochondrial ribosomal protein L4
chr1_-_156923111	0.720	NM_003126	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr12_+_102883687	0.711	NM_003211	TDG	thymine-DNA glycosylase
chr6_-_53321658	0.707		ELOVL5	ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
chr11_-_76862197	0.704	NM_001128620 NM_002576	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1
chr7_+_107318854	0.701		DLD	dihydrolipoamide dehydrogenase
chr19_+_18145619	0.700		IFI30	interferon, gamma-inducible protein 30
chr14_-_54563554	0.697	NM_001008396 NM_007086	WDHD1	WD repeat and HMG-box DNA binding protein 1
chr1_-_201162938	0.684		KLHL12	kelch-like 12 (Drosophila)
chr10_-_64246129	0.684	NM_000399 NM_001136177 NM_001136179	EGR2	early growth response 2
chr7_+_140042932	0.683	NM_004546	NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr7_+_107318852	0.682		DLD	dihydrolipoamide dehydrogenase
chr6_-_106880300	0.681	NM_004849	ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)
chr8_-_17148637	0.680	NM_013354 NM_054026	CNOT7	CCR4-NOT transcription complex, subunit 7
chrX_+_12903145	0.679	NM_021109 NM_183049	TMSB4X TMSL3	thymosin beta 4, X-linked thymosin-like 3
chr6_-_34772495	0.677		C6orf106	chromosome 6 open reading frame 106
chr8_+_26204921	0.666	NM_002717	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr1_-_46957377	0.656		KIAA0494	KIAA0494
chr16_+_1979959	0.651	NM_004209	SYNGR3	synaptogyrin 3
chr16_-_20819061	0.645	NM_173475	DCUN1D3	DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr11_-_28086222	0.644		KIF18A	kinesin family member 18A
chr10_-_99084417	0.640	NM_012083	FRAT2	frequently rearranged in advanced T-cell lymphomas 2
chr8_+_42315132	0.635	NM_002690	POLB	polymerase (DNA directed), beta
chr18_-_257987	0.634	NM_005131	THOC1	THO complex 1
chr11_-_3775282	0.632		NUP98	nucleoporin 98kDa
chr6_+_47553399	0.627	NM_012120	CD2AP	CD2-associated protein
chr8_+_23442331	0.616		SLC25A37	solute carrier family 25, member 37
chr5_+_44844724	0.616	NM_016640	MRPS30	mitochondrial ribosomal protein S30
chr11_+_118460779	0.614	NM_000190	HMBS	hydroxymethylbilane synthase
chr8_+_26204997	0.610		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr12_-_131194794	0.609	NM_175066	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr17_-_37794102	0.609		STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)
chr1_-_148818629	0.607		MCL1	myeloid cell leukemia sequence 1 (BCL2-related)
chr7_+_23187970	0.600	NM_007342	NUPL2	nucleoporin like 2
chr16_+_54782802	0.599		GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr19_+_10223598	0.597	NM_015956 NM_146387 NM_146388	MRPL4	mitochondrial ribosomal protein L4
chr1_+_154297588	0.597	NM_020387	RAB25	RAB25, member RAS oncogene family
chr7_+_100302885	0.591	NM_003302	TRIP6	thyroid hormone receptor interactor 6
chr11_-_3775312	0.589		NUP98	nucleoporin 98kDa
chr5_-_133589670	0.585		PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme
chr2_+_60962279	0.585		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr5_-_133589644	0.580		PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme
chr19_-_14390853	0.577		DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr19_-_14391129	0.577		DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr7_+_55987046	0.572	NM_015969	MRPS17	mitochondrial ribosomal protein S17
chr3_-_33734747	0.564	NM_015097	CLASP2	cytoplasmic linker associated protein 2
chr3_-_151963607	0.563		SIAH2	seven in absentia homolog 2 (Drosophila)
chr19_-_45028858	0.561	NM_001436	FBL	fibrillarin
chr7_-_45117797	0.549		TBRG4	transforming growth factor beta regulator 4
chr19_-_45028784	0.548		FBL	fibrillarin
chr13_+_33290254	0.548		RFC3	replication factor C (activator 1) 3, 38kDa
chr12_-_121946561	0.546
chr7_+_106991638	0.546	NM_181581	DUS4L	dihydrouridine synthase 4-like (S. cerevisiae)
chr1_+_210275752	0.543		DTL	denticleless homolog (Drosophila)
chr19_+_1018536	0.542		HMHA1	histocompatibility (minor) HA-1
chr19_-_51912136	0.541	NM_001079880 NM_001079881 NM_016457	PRKD2	protein kinase D2
chr20_-_55718351	0.541	NM_020182	PMEPA1	prostate transmembrane protein, androgen induced 1
chr12_+_4253143	0.533	NM_001759	CCND2	cyclin D2
chr22_+_21011653	0.531
chr8_-_17148474	0.531		CNOT7	CCR4-NOT transcription complex, subunit 7
chr22_+_19601721	0.530		CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr18_+_2561587	0.529		NDC80	NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr12_+_109956210	0.528	NM_015267	CUX2	cut-like homeobox 2
chr22_+_19601619	0.524	NM_005207	CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr4_+_109130457	0.523		HADH	hydroxyacyl-CoA dehydrogenase
chr7_+_44612745	0.521		OGDH	oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr1_-_226712140	0.520	NM_033445	HIST3H2A	histone cluster 3, H2a
chr19_-_52308848	0.520	NM_015168	ZC3H4	zinc finger CCCH-type containing 4
chr19_-_45028837	0.520		FBL	fibrillarin
chr5_-_138238953	0.518	NM_015564	LRRTM2	leucine rich repeat transmembrane neuronal 2
chrX_-_141120722	0.518	NM_016249	MAGEC2	melanoma antigen family C, 2
chr1_+_91738953	0.517	NM_001134419 NM_003503	CDC7	cell division cycle 7 homolog (S. cerevisiae)
chr4_+_142361494	0.517	NM_014487	ZNF330	zinc finger protein 330
chr5_-_16561936	0.516	NM_019000	FAM134B	family with sequence similarity 134, member B
chr1_-_201162991	0.515	NM_021633	KLHL12	kelch-like 12 (Drosophila)
chr3_-_102878301	0.515	NM_014415	ZBTB11	zinc finger and BTB domain containing 11
chr11_+_66367458	0.513	NM_001032279 NM_005133	RCE1	RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr11_+_108040983	0.513	NM_004398	DDX10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr2_+_60962206	0.512		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr4_+_109130491	0.510		HADH	hydroxyacyl-CoA dehydrogenase
chr6_-_27208507	0.509	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr18_+_2561509	0.507	NM_006101	NDC80	NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr8_+_23442307	0.506	NM_016612	SLC25A37	solute carrier family 25, member 37
chr4_-_84475328	0.504	NM_001166498 NM_006665	HPSE	heparanase
chr3_+_157877146	0.495	NM_001184718	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr10_-_64246080	0.492		EGR2	early growth response 2
chr4_+_142361523	0.485		ZNF330	zinc finger protein 330
chr8_-_131098015	0.483		FAM49B	family with sequence similarity 49, member B
chr6_-_106879983	0.482		ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)
chr9_-_168913	0.480	NM_001145355 NM_001145356 NM_018491	CBWD2 CBWD1	COBW domain containing 2 COBW domain containing 1
chr10_-_23043449	0.479	NM_005028	PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr12_+_131194962	0.477
chr22_+_20101661	0.476	NM_015094	HIC2	hypermethylated in cancer 2
chr19_-_34395947	0.475	NM_006003	UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr11_+_18300689	0.475		GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa
chr2_-_10506033	0.474		ODC1	ornithine decarboxylase 1
chr4_+_109130318	0.471	NM_001184705 NM_005327	HADH	hydroxyacyl-CoA dehydrogenase
chr6_-_42821800	0.470		TBCC	tubulin folding cofactor C
chr19_-_14391155	0.470	NM_005804	DDX39A	DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr21_+_44033821	0.469	NM_003683	RRP1	ribosomal RNA processing 1 homolog (S. cerevisiae)
chr7_+_116447527	0.467		ST7	suppression of tumorigenicity 7
chr1_-_147665783	0.467		HIST2H2BF	histone cluster 2, H2bf
chr6_-_42821815	0.466	NM_003192	TBCC	tubulin folding cofactor C
chr2_+_96365233	0.466		NCAPH	non-SMC condensin I complex, subunit H
chr1_-_154964812	0.464		ISG20L2	interferon stimulated exonuclease gene 20kDa-like 2
chr7_-_127833231	0.461	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr5_-_138238891	0.461		CTNNA1 LRRTM2	catenin (cadherin-associated protein), alpha 1, 102kDa leucine rich repeat transmembrane neuronal 2
chr2_+_60962228	0.457	NM_002908	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr1_-_51198383	0.456		FAF1	Fas (TNFRSF6) associated factor 1
chr18_+_70314315	0.450	NM_018235	CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr1_-_31542178	0.450	NM_004814	SNRNP40	small nuclear ribonucleoprotein 40kDa (U5)
chr9_+_70046658	0.449	NM_201453	CBWD5 CBWD3 CBWD1 CBWD6	COBW domain containing 5 COBW domain containing 3 COBW domain containing 1 COBW domain containing 6
chr9_-_69729943	0.447		CBWD3	COBW domain containing 3
chr1_-_227710619	0.446		NUP133	nucleoporin 133kDa
chr22_+_25209812	0.444	NM_001013694	SRRD	SRR1 domain containing
chr1_+_44213200	0.444		ATP6V0B	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr16_+_79598348	0.443		CENPN	centromere protein N
chrX_+_41078353	0.442		DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr2_+_113911737	0.441	NM_172003	CBWD2 CBWD1	COBW domain containing 2 COBW domain containing 1
chr4_-_146238746	0.441	NM_014885	ANAPC10	anaphase promoting complex subunit 10
chr7_+_16759845	0.440	NM_014399	TSPAN13	tetraspanin 13
chr1_-_226357552	0.438	NM_024319	C1orf35	chromosome 1 open reading frame 35
chr14_+_99774854	0.437	NM_003403	YY1	YY1 transcription factor
chr3_+_130081161	0.431		ACAD9	acyl-CoA dehydrogenase family, member 9
chr22_+_21116283	0.431
chr11_+_34083686	0.430	NM_001144030 NM_024662	NAT10	N-acetyltransferase 10 (GCN5-related)
chr15_+_78232232	0.429		FAH	fumarylacetoacetate hydrolase (fumarylacetoacetase)
chrX_-_7855400	0.425	NM_004650	PNPLA4	patatin-like phospholipase domain containing 4
chr9_-_69729926	0.425		CBWD5 CBWD3 CBWD6	COBW domain containing 5 COBW domain containing 3 COBW domain containing 6
chr9_-_69729965	0.423		CBWD5	COBW domain containing 5
chr9_-_69729958	0.423		CBWD6	COBW domain containing 6
chr3_-_198960964	0.422	NM_001145642	KIAA0226	KIAA0226
chr1_-_227710700	0.421	NM_018230	NUP133	nucleoporin 133kDa
chr16_+_54782751	0.418	NM_020988 NM_138736	GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chrX_-_15421279	0.418	NM_001018109 NM_003662	PIR	pirin (iron-binding nuclear protein)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.57	1.13e-10	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.51	3.79e-10	GO:0034641	cellular nitrogen compound metabolic process
1.40	8.88e-10	GO:0044260	cellular macromolecule metabolic process
1.62	1.51e-09	GO:0090304	nucleic acid metabolic process
1.48	2.97e-09	GO:0006807	nitrogen compound metabolic process
1.29	1.46e-08	GO:0044237	cellular metabolic process
1.28	4.68e-08	GO:0044238	primary metabolic process
1.33	2.71e-07	GO:0043170	macromolecule metabolic process
1.22	5.06e-06	GO:0008152	metabolic process
1.95	5.89e-05	GO:0022403	cell cycle phase
1.86	9.03e-05	GO:0022402	cell cycle process
1.52	3.03e-04	GO:0016070	RNA metabolic process
1.49	4.00e-04	GO:0010467	gene expression
1.53	5.89e-04	GO:0006996	organelle organization
1.92	1.26e-03	GO:0000278	mitotic cell cycle
1.88	1.57e-03	GO:0051276	chromosome organization
1.65	2.89e-03	GO:0007049	cell cycle
1.67	1.03e-02	GO:0033554	cellular response to stress
2.77	1.05e-02	GO:0071103	DNA conformation change
1.34	1.13e-02	GO:0071841	cellular component organization or biogenesis at cellular level
1.44	1.52e-02	GO:0034645	cellular macromolecule biosynthetic process
1.86	1.70e-02	GO:0006974	response to DNA damage stimulus
1.44	1.82e-02	GO:0009059	macromolecule biosynthetic process
4.10	2.01e-02	GO:0000723	telomere maintenance
3.15	2.51e-02	GO:0031497	chromatin assembly
4.02	2.60e-02	GO:0032200	telomere organization
1.33	2.70e-02	GO:0071842	cellular component organization at cellular level
1.75	2.96e-02	GO:0006396	RNA processing
2.05	4.32e-02	GO:0051325	interphase
1.76	4.78e-02	GO:0006259	DNA metabolic process
2.66	4.85e-02	GO:0006333	chromatin assembly or disassembly

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.09e-13	GO:0044424	intracellular part
1.38	2.80e-13	GO:0005634	nucleus
1.16	1.24e-11	GO:0005622	intracellular
1.22	6.51e-10	GO:0043231	intracellular membrane-bounded organelle
1.21	8.85e-10	GO:0043227	membrane-bounded organelle
1.19	2.55e-09	GO:0043229	intracellular organelle
1.18	4.33e-09	GO:0043226	organelle
2.22	5.83e-08	GO:0005694	chromosome
1.55	7.68e-08	GO:0044428	nuclear part
1.58	3.66e-07	GO:0031981	nuclear lumen
1.51	4.24e-07	GO:0070013	intracellular organelle lumen
1.28	7.18e-07	GO:0044446	intracellular organelle part
2.25	9.02e-07	GO:0044427	chromosomal part
1.49	9.22e-07	GO:0043233	organelle lumen
1.67	1.25e-06	GO:0005654	nucleoplasm
1.48	1.38e-06	GO:0031974	membrane-enclosed lumen
1.26	3.00e-06	GO:0044422	organelle part
1.36	6.47e-04	GO:0043228	non-membrane-bounded organelle
1.36	6.47e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.30	6.62e-04	GO:0032991	macromolecular complex
1.35	1.02e-02	GO:0005829	cytosol
2.61	1.76e-02	GO:0000775	chromosome, centromeric region
1.13	1.77e-02	GO:0005737	cytoplasm
2.52	2.93e-02	GO:0000793	condensed chromosome
2.84	3.07e-02	GO:0032993	protein-DNA complex
11.62	4.08e-02	GO:0005663	DNA replication factor C complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.43	5.70e-07	GO:0003676	nucleic acid binding
1.58	1.99e-05	GO:0030554	adenyl nucleotide binding
1.19	2.59e-05	GO:0005515	protein binding
1.58	2.64e-05	GO:0032559	adenyl ribonucleotide binding
1.58	3.47e-05	GO:0005524	ATP binding
1.44	8.88e-05	GO:0000166	nucleotide binding
1.10	1.34e-04	GO:0005488	binding
1.48	2.13e-04	GO:0035639	purine ribonucleoside triphosphate binding
1.47	3.02e-04	GO:0017076	purine nucleotide binding
1.43	3.32e-04	GO:0003677	DNA binding
1.46	3.58e-04	GO:0032553	ribonucleotide binding
1.46	3.58e-04	GO:0032555	purine ribonucleotide binding
1.19	3.95e-02	GO:0003824	catalytic activity