Motif ID: GTF2I.p2

Z-value: 1.571


Transcription factors associated with GTF2I.p2:

Gene SymbolEntrez IDGene Name
GTF2I 2969 general transcription factor II, i

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2Ichr7_+_737099910.342.0e-01Click!


Activity profile for motif GTF2I.p2.

activity profile for motif GTF2I.p2


Sorted Z-values histogram for motif GTF2I.p2

Sorted Z-values for motif GTF2I.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2I.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_20685314 5.211 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_-_227371698 3.435 NM_005544
IRS1
insulin receptor substrate 1
chr2_-_218551786 3.051 TNS1
tensin 1
chr5_+_135392482 2.936 NM_000358
TGFBI
transforming growth factor, beta-induced, 68kDa
chr8_+_97575317 2.781 SDC2
syndecan 2
chr8_+_97575196 2.768 SDC2
syndecan 2
chr8_+_97575244 2.764 SDC2
syndecan 2
chr2_-_39517934 2.540 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr19_+_50144267 2.510 APOC2
apolipoprotein C-II
chr12_-_113606322 2.435 NM_005996
NM_016569
TBX3

T-box 3

chr2_-_39517795 2.413 MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr3_-_187025501 2.296 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr10_+_114699953 2.234 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr5_+_92944680 2.214 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr14_-_53493198 2.060 NM_001202
NM_130850
BMP4

bone morphogenetic protein 4

chr2_-_39517633 2.022 NM_003618
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr22_-_34566276 2.011 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_-_128485134 1.937 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr4_-_1156959 1.915 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr22_-_34566210 1.892 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr11_-_2116048 1.869 IGF2
insulin-like growth factor 2 (somatomedin A)
chr8_+_97575370 1.866 SDC2
syndecan 2
chrX_+_54851500 1.842 NM_014599
MAGED2
melanoma antigen family D, 2
chr20_-_22512893 1.790 FOXA2
forkhead box A2
chrX_+_138060 1.769 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chrY_+_138060 1.769 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr8_+_97575052 1.741 NM_002998
SDC2
syndecan 2
chr2_-_227372574 1.680 IRS1
insulin receptor substrate 1
chr2_-_168812132 1.673 NM_013233
STK39
serine threonine kinase 39
chr5_-_111120817 1.636 NM_004772
C5orf13
chromosome 5 open reading frame 13
chrX_-_128485121 1.622 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr11_-_2116775 1.608 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_92124201 1.595 NM_001195683
NM_003243
TGFBR3

transforming growth factor, beta receptor III

chr3_+_189354167 1.588 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr16_-_29817841 1.566 NM_001114099
NM_001114100
NM_012410
NM_201575
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr8_+_26427378 1.556 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr22_-_34566367 1.547 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr4_-_16509446 1.544 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr4_-_16509354 1.518 LDB2
LIM domain binding 2
chr11_-_2116501 1.511 IGF2
insulin-like growth factor 2 (somatomedin A)
chr4_-_1156533 1.507 NM_012445
SPON2
spondin 2, extracellular matrix protein
chrX_-_128485062 1.492 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr7_-_149669622 1.463 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr2_+_62786290 1.460 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr11_-_2116360 1.456 IGF2
insulin-like growth factor 2 (somatomedin A)
chr5_-_111120929 1.456 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr2_+_187162969 1.455 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr14_+_20608179 1.454 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr1_-_92124064 1.438 TGFBR3
transforming growth factor, beta receptor III
chr2_+_127892459 1.432 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr13_+_97593469 1.418 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_187025438 1.410 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_85819004 1.406 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr5_-_111120764 1.402 C5orf13
chromosome 5 open reading frame 13
chr2_+_127892489 1.397 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr13_+_97593411 1.394 NM_001001715
NM_005766
FARP1

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

chr6_+_1335067 1.378 NM_001452
FOXF2
forkhead box F2
chr14_+_31616196 1.369 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr11_-_27697768 1.357 NM_001143807
BDNF
brain-derived neurotrophic factor
chrX_-_20194831 1.314 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr5_-_172689111 1.280 NM_003714
STC2
stanniocalcin 2
chr17_+_50697355 1.274 HLF
hepatic leukemia factor
chr19_+_40321567 1.268 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_40321584 1.266 FXYD1
FXYD domain containing ion transport regulator 1
chr16_+_68157370 1.258 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr13_+_97593711 1.250 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr2_+_46779827 1.244 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr1_-_150233337 1.234 NM_002966
S100A10
S100 calcium binding protein A10
chr17_-_34157962 1.225 NM_007144
PCGF2
polycomb group ring finger 2
chr4_-_81213207 1.221


chr3_-_31997738 1.205 OSBPL10
oxysterol binding protein-like 10
chr16_-_10581944 1.202 NM_001424
EMP2
epithelial membrane protein 2
chr12_+_54760153 1.199 NM_001005915
NM_001982
ERBB3

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

chr19_+_54708247 1.198 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr1_-_150232900 1.179 S100A10
S100 calcium binding protein A10
chr14_+_22845851 1.167 NM_004050
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 read-through transcript
BCL2-like 2
chr17_-_38421363 1.163 VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr11_-_86343859 1.158 NM_012193
FZD4
frizzled homolog 4 (Drosophila)
chr8_+_97575071 1.150 SDC2
syndecan 2
chr14_-_53491019 1.148 NM_130851
BMP4
bone morphogenetic protein 4
chr2_-_161058550 1.134 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr19_+_54708312 1.125 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr4_+_184257337 1.120 NM_024949
WWC2
WW and C2 domain containing 2
chr10_+_31648103 1.108 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr13_-_95094920 1.106 NM_014934
NM_198968
DZIP1

DAZ interacting protein 1

chr6_-_16869579 1.069 NM_000332
NM_001128164
ATXN1

ataxin 1

chrX_+_152413540 1.067 NM_001711
BGN
biglycan
chr22_-_34754343 1.053 NM_001082578
NM_001082579
RBFOX2

RNA binding protein, fox-1 homolog (C. elegans) 2

chr19_-_6671585 1.049 NM_000064
C3
complement component 3
chr5_+_52812165 1.048 FST
follistatin
chr6_-_134538762 1.034 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr1_-_68470585 1.024 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr7_+_29200636 0.993 NM_004067
CHN2
chimerin (chimaerin) 2
chr14_-_52487558 0.991 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr19_-_18578577 0.974 CRLF1
cytokine receptor-like factor 1
chr16_-_71650034 0.970 NM_001164766
ZFHX3
zinc finger homeobox 3
chr4_-_16509126 0.957 LDB2
LIM domain binding 2
chr5_-_149515331 0.955 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr14_-_88953059 0.944 NM_005197
FOXN3
forkhead box N3
chr16_+_84202515 0.942 NM_001134473
KIAA0182
KIAA0182
chr8_+_30361485 0.938 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chr7_+_93976927 0.931 NM_022900
CASD1
CAS1 domain containing 1
chr5_-_121441910 0.928 NM_002317
LOX
lysyl oxidase
chr16_+_68157611 0.917 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr5_+_52812236 0.912 NM_006350
NM_013409
FST

follistatin

chr6_-_52549774 0.903 NM_012288
TRAM2
translocation associated membrane protein 2
chr4_-_1156378 0.901 SPON2
spondin 2, extracellular matrix protein
chr6_-_134538526 0.895 SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_167342493 0.893 NM_001677
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr1_+_162795328 0.889 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr4_-_1156362 0.888 SPON2
spondin 2, extracellular matrix protein
chr4_-_158111995 0.887 NM_016205
PDGFC
platelet derived growth factor C
chr3_+_37878647 0.872 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr1_+_167342149 0.868 ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_21120314 0.861 APOB
apolipoprotein B (including Ag(x) antigen)
chr15_-_35179614 0.861 MEIS2
Meis homeobox 2
chr11_+_12355600 0.861 NM_018222
PARVA
parvin, alpha
chr1_+_201711578 0.860 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr17_-_7095982 0.856 NM_015343
CTDNEP1
CTD nuclear envelope phosphatase 1
chrX_-_20195062 0.839 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr22_+_44277354 0.831 NM_001996
NM_006485
NM_006486
NM_006487
FBLN1



fibulin 1



chr17_+_43082302 0.831 KPNB1
karyopherin (importin) beta 1
chr14_-_37134191 0.826 NM_004496
FOXA1
forkhead box A1
chr7_+_93862137 0.820 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr14_-_60185659 0.820 NM_005982
SIX1
SIX homeobox 1
chr7_+_73506172 0.810 GTF2IRD1
GTF2I repeat domain containing 1
chr19_+_54707739 0.809 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr6_+_107917965 0.805 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chrX_+_152413646 0.804 BGN
biglycan
chr16_+_31390567 0.803 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr3_-_50324815 0.798 NM_153281
HYAL1
hyaluronoglucosaminidase 1
chr7_+_93977267 0.795 CASD1
CAS1 domain containing 1
chr3_-_8668723 0.793 NM_015931
C3orf32
chromosome 3 open reading frame 32
chr3_+_23961739 0.783 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr7_-_107430566 0.779 NM_002291
LAMB1
laminin, beta 1
chr7_-_94123362 0.778 SGCE
sarcoglycan, epsilon
chr3_+_54131731 0.777 NM_018398
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr8_+_22492198 0.777 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr11_-_70350292 0.776 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr7_+_93861808 0.774 NM_000089
COL1A2
collagen, type I, alpha 2
chr7_-_94123413 0.768 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr17_+_64020155 0.764 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr17_+_38088097 0.764 NM_003632
CNTNAP1
contactin associated protein 1
chr6_-_31805547 0.761 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr2_-_174537021 0.757 NM_001017371
SP3
Sp3 transcription factor
chr2_+_46779553 0.756 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr7_-_94123308 0.754 SGCE
sarcoglycan, epsilon
chr20_-_22513050 0.752 NM_021784
FOXA2
forkhead box A2
chr11_-_2108035 0.751 IGF2
insulin-like growth factor 2 (somatomedin A)
chr16_-_63713382 0.747 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr19_+_40213431 0.747 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr12_-_123023312 0.738 CCDC92
coiled-coil domain containing 92
chr2_+_54536780 0.736 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr3_-_126088530 0.731 ITGB5
integrin, beta 5
chr1_+_203740306 0.728 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr17_+_25730107 0.725 NM_001304
CPD
carboxypeptidase D
chr3_+_54131613 0.724 CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chrX_-_130251068 0.722 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr12_-_105165805 0.719 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr16_-_63713466 0.719 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr19_-_53586549 0.712 NM_006801
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr1_-_150232927 0.708 S100A10
S100 calcium binding protein A10
chr9_-_16860719 0.705 NM_017637
BNC2
basonuclin 2
chr5_-_149515613 0.705 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr21_+_39099624 0.702 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr5_+_150380325 0.701 GPX3
glutathione peroxidase 3 (plasma)
chr16_-_63713485 0.700 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr8_-_134653194 0.698 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr6_+_151602787 0.693 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr1_+_201711505 0.693 NM_002725
NM_201348
PRELP

proline/arginine-rich end leucine-rich repeat protein

chr1_+_202308814 0.691 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr2_-_21120420 0.690 NM_000384
APOB
apolipoprotein B (including Ag(x) antigen)
chr15_-_35179650 0.688 NM_170674
NM_170675
NM_170676
NM_170677
MEIS2



Meis homeobox 2



chr2_-_166940710 0.684 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr10_-_62373828 0.683 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr20_+_43468617 0.679 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr3_+_106568430 0.677 ALCAM
activated leukocyte cell adhesion molecule
chr6_+_151603201 0.669 AKAP12
A kinase (PRKA) anchor protein 12
chr19_-_53586427 0.667 KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr2_+_36436873 0.665 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr19_+_54708302 0.664 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr5_-_149515502 0.664 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr12_+_54760211 0.664 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr12_-_45052286 0.660 SLC38A2
solute carrier family 38, member 2
chr1_+_212228482 0.655 NM_002763
PROX1
prospero homeobox 1
chr17_+_50697319 0.650 NM_002126
HLF
hepatic leukemia factor
chr7_+_73506047 0.646 NM_016328
GTF2IRD1
GTF2I repeat domain containing 1
chr15_-_59308708 0.645 RORA
RAR-related orphan receptor A
chr17_+_43082273 0.644 NM_002265
KPNB1
karyopherin (importin) beta 1
chr21_+_39099717 0.643 NM_005239
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr7_+_100557098 0.640 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chrX_-_130250880 0.640 IGSF1
immunoglobulin superfamily, member 1
chr15_-_88148177 0.640 ANPEP
alanyl (membrane) aminopeptidase
chr15_-_56829069 0.637 ADAM10
ADAM metallopeptidase domain 10
chr6_+_37245860 0.633 NM_002648
PIM1
pim-1 oncogene
chr17_+_24394281 0.630 PIPOX
pipecolic acid oxidase
chr2_+_8739563 0.628 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr6_+_31976754 0.627 NM_001178063
C2
complement component 2
chr7_+_73506333 0.627 NM_005685
GTF2IRD1
GTF2I repeat domain containing 1
chr4_-_39205316 0.626 UGDH
UDP-glucose 6-dehydrogenase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.17 3.89e-06 GO:0007275 multicellular organismal development
1.27 6.41e-06 GO:0007399 nervous system development
1.18 7.17e-06 GO:0048731 system development
1.15 2.32e-05 GO:0032502 developmental process
1.33 3.11e-05 GO:0022008 neurogenesis
1.15 4.02e-05 GO:0023052 signaling
1.44 6.47e-05 GO:0000904 cell morphogenesis involved in differentiation
1.16 9.30e-05 GO:0048856 anatomical structure development
1.20 1.02e-04 GO:0048523 negative regulation of cellular process
1.33 1.08e-04 GO:0048699 generation of neurons
1.09 1.52e-04 GO:0050794 regulation of cellular process
1.39 2.10e-04 GO:0000902 cell morphogenesis
1.12 2.41e-04 GO:0032501 multicellular organismal process
1.23 3.36e-04 GO:0009653 anatomical structure morphogenesis
1.35 4.17e-04 GO:0030182 neuron differentiation
1.22 4.22e-04 GO:0023051 regulation of signaling
1.18 5.03e-04 GO:0048519 negative regulation of biological process
1.36 5.33e-04 GO:0030030 cell projection organization
1.37 5.62e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.24 6.38e-04 GO:0009966 regulation of signal transduction
1.36 6.58e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
1.36 7.27e-04 GO:0032989 cellular component morphogenesis
1.35 7.54e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.34 8.01e-04 GO:0009890 negative regulation of biosynthetic process
1.52 8.06e-04 GO:0051130 positive regulation of cellular component organization
1.17 1.40e-03 GO:0048522 positive regulation of cellular process
1.36 1.60e-03 GO:0010629 negative regulation of gene expression
1.38 1.88e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.15 2.21e-03 GO:0048518 positive regulation of biological process
1.07 2.75e-03 GO:0065007 biological regulation
1.08 3.10e-03 GO:0050789 regulation of biological process
1.49 3.46e-03 GO:0001944 vasculature development
1.38 3.67e-03 GO:0072358 cardiovascular system development
1.38 3.67e-03 GO:0072359 circulatory system development
1.37 4.04e-03 GO:0051253 negative regulation of RNA metabolic process
1.35 4.11e-03 GO:0048666 neuron development
1.13 4.27e-03 GO:0007165 signal transduction
1.26 8.20e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.47 8.85e-03 GO:0060284 regulation of cell development
1.37 8.86e-03 GO:0031175 neuron projection development
1.29 8.97e-03 GO:2000026 regulation of multicellular organismal development
1.26 9.11e-03 GO:0032879 regulation of localization
1.36 9.24e-03 GO:0048858 cell projection morphogenesis
1.38 9.57e-03 GO:0048812 neuron projection morphogenesis
1.38 1.09e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.83 1.19e-02 GO:0030324 lung development
1.32 1.23e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.81 1.51e-02 GO:0030323 respiratory tube development
1.32 1.63e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 1.83e-02 GO:0051128 regulation of cellular component organization
1.35 1.84e-02 GO:0032990 cell part morphogenesis
1.47 2.14e-02 GO:0001568 blood vessel development
1.29 2.25e-02 GO:0019220 regulation of phosphate metabolic process
1.29 2.25e-02 GO:0051174 regulation of phosphorus metabolic process
1.38 2.35e-02 GO:0007409 axonogenesis
1.25 2.58e-02 GO:0050793 regulation of developmental process
1.89 3.25e-02 GO:0022612 gland morphogenesis
1.30 3.65e-02 GO:0001932 regulation of protein phosphorylation
1.16 3.98e-02 GO:0030154 cell differentiation
1.25 4.28e-02 GO:0048468 cell development
1.22 4.65e-02 GO:0051246 regulation of protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 1.47e-04 GO:0042995 cell projection
1.69 4.65e-04 GO:0005912 adherens junction
1.35 6.53e-04 GO:0030054 cell junction
1.06 1.30e-03 GO:0005737 cytoplasm
1.80 1.47e-03 GO:0005925 focal adhesion
1.76 2.74e-03 GO:0005924 cell-substrate adherens junction
1.39 3.43e-03 GO:0043005 neuron projection
1.59 4.66e-03 GO:0070161 anchoring junction
1.39 5.10e-03 GO:0045202 synapse
1.55 6.82e-03 GO:0031252 cell leading edge
1.48 8.27e-03 GO:0016323 basolateral plasma membrane
1.69 1.21e-02 GO:0030055 cell-substrate junction
2.21 4.59e-02 GO:0032432 actin filament bundle

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.09 1.27e-06 GO:0005515 protein binding
1.47 1.14e-03 GO:0003779 actin binding
1.29 1.00e-02 GO:0043565 sequence-specific DNA binding
1.32 1.06e-02 GO:0008092 cytoskeletal protein binding
1.04 1.52e-02 GO:0005488 binding
1.23 2.38e-02 GO:0001071 nucleic acid binding transcription factor activity
1.23 2.38e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.25 2.88e-02 GO:0019899 enzyme binding
2.06 3.85e-02 GO:0008013 beta-catenin binding