Motif ID: CTCF.p2

Z-value: 1.168


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CTCFchr16_+_661538100.766.9e-04Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_-_21231421 1.865 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr22_+_21027538 1.259


chr1_+_210275541 1.103 NM_016448
DTL
denticleless homolog (Drosophila)
chr22_+_18085990 1.056 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr22_+_21053972 1.019


chr1_-_224662156 1.008 PARP1
poly (ADP-ribose) polymerase 1
chr14_+_30413393 0.988 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr10_+_80777199 0.961 NM_005729
PPIF
peptidylprolyl isomerase F
chr10_+_13243553 0.914 NM_018518
NM_182751
MCM10

minichromosome maintenance complex component 10

chr1_-_200396354 0.910 NM_002832
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr16_+_170334 0.910 NM_005331
HBQ1
hemoglobin, theta 1
chr10_+_80777248 0.901 PPIF
peptidylprolyl isomerase F
chr17_-_5283104 0.880 C1QBP
complement component 1, q subcomponent binding protein
chr19_-_46551670 0.870 NM_000660
TGFB1
transforming growth factor, beta 1
chr16_-_2330738 0.855 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr16_-_2330712 0.833 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr16_+_2807228 0.831 PRSS21
protease, serine, 21 (testisin)
chr21_-_25901644 0.807 NM_017446
NM_080794
MRPL39

mitochondrial ribosomal protein L39

chr2_+_6974922 0.758 NM_014746
RNF144A
ring finger protein 144A
chr17_-_5283148 0.752 NM_001212
C1QBP
complement component 1, q subcomponent binding protein
chr22_+_21079355 0.745


chr15_+_72861767 0.738 CSK
c-src tyrosine kinase
chr17_-_30493254 0.729 NLE1
notchless homolog 1 (Drosophila)
chr3_-_188339882 0.708 NM_052969
RPL39L
ribosomal protein L39-like
chr1_+_114249549 0.688 DCLRE1B
DNA cross-link repair 1B
chr8_-_102286695 0.683 ZNF706
zinc finger protein 706
chr1_+_114249429 0.682 NM_022836
DCLRE1B
DNA cross-link repair 1B
chr8_-_102287044 0.669 NM_001042511
ZNF706
zinc finger protein 706
chr8_-_101641046 0.658 NM_198401
GAPDHP62
ANKRD46
glyceraldehyde 3 phosphate dehydrogenase pseudogene 62
ankyrin repeat domain 46
chr22_+_18085891 0.658 SEPT5
septin 5
chr1_-_224662307 0.657 PARP1
poly (ADP-ribose) polymerase 1
chr11_-_65962836 0.640 NM_016050
NM_170738
NM_170739
MRPL11


mitochondrial ribosomal protein L11


chr15_-_36644122 0.633 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr1_-_24067347 0.632 NM_000147
FUCA1
fucosidase, alpha-L- 1, tissue
chr22_+_21116283 0.621


chr7_-_22506320 0.620 NM_001164460
NM_207342
MGC87042

STEAP family protein MGC87042

chr16_+_29735208 0.614 C16orf53
chromosome 16 open reading frame 53
chr10_+_80777234 0.611 PPIF
peptidylprolyl isomerase F
chr8_+_43067817 0.609


chr10_+_35455986 0.597 CREM
cAMP responsive element modulator
chr1_-_224662368 0.590 PARP1
poly (ADP-ribose) polymerase 1
chr17_+_22996461 0.588 LGALS9
lectin, galactoside-binding, soluble, 9
chr12_+_118590039 0.576 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr19_+_17277476 0.574 NM_023937
MRPL34
mitochondrial ribosomal protein L34
chr15_+_72861470 0.570 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr8_-_102287083 0.570 NM_001042510
NM_016096
ZNF706

zinc finger protein 706

chr17_-_73694669 0.570 NM_003258
TK1
thymidine kinase 1, soluble
chr9_+_138680064 0.555 EGFL7
EGF-like-domain, multiple 7
chr17_-_52393364 0.555 NM_004645
COIL
coilin
chr7_+_6596183 0.551 NM_024067
C7orf26
chromosome 7 open reading frame 26
chr1_-_224662396 0.549 PARP1
poly (ADP-ribose) polymerase 1
chr11_+_20365788 0.549 PRMT3
protein arginine methyltransferase 3
chr3_-_129694717 0.545 NM_032638
GATA2
GATA binding protein 2
chr9_+_70840463 0.542 FXN
frataxin
chr7_-_134506070 0.542 NM_024033
C7orf49
chromosome 7 open reading frame 49
chr11_+_20365651 0.540 NM_001145166
NM_001145167
NM_005788
PRMT3


protein arginine methyltransferase 3


chr10_+_35455806 0.538 NM_001881
NM_182850
NM_182853
NM_183013
CREM



cAMP responsive element modulator



chr7_-_134506001 0.537 C7orf49
chromosome 7 open reading frame 49
chr1_-_224662419 0.537 NM_001618
PARP1
poly (ADP-ribose) polymerase 1
chr7_-_134506012 0.527 C7orf49
chromosome 7 open reading frame 49
chr7_+_63980305 0.526 ZNF273
zinc finger protein 273
chr22_+_20880112 0.521


chr3_+_47841478 0.513 DHX30
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr16_+_22216223 0.503 NM_018119
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr10_+_80777265 0.502 PPIF
peptidylprolyl isomerase F
chr7_-_134505923 0.498 C7orf49
chromosome 7 open reading frame 49
chr14_-_105644300 0.498 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr9_+_70840298 0.498 NM_000144
NM_001161706
NM_181425
FXN


frataxin


chr17_+_7532391 0.490 NM_001143992
NM_018081
WRAP53

WD repeat containing, antisense to TP53

chr1_+_28717234 0.489 NM_001048194
NM_001048195
NM_001269
RCC1


regulator of chromosome condensation 1


chr17_-_30493382 0.486 NM_001014445
NM_018096
NLE1

notchless homolog 1 (Drosophila)

chr8_-_91066060 0.484 NM_002485
NBN
nibrin
chr19_-_2002222 0.482 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chr16_-_2241561 0.479 NM_001178029
NM_001919
DCI

dodecenoyl-CoA isomerase

chr16_-_2037819 0.478 NM_002528
NTHL1
nth endonuclease III-like 1 (E. coli)
chr1_-_224662413 0.477 PARP1
poly (ADP-ribose) polymerase 1
chr4_-_106614562 0.475 NM_006903
NM_176866
NM_176867
NM_176869
PPA2



pyrophosphatase (inorganic) 2



chr1_-_38228179 0.463 NM_006802
SF3A3
splicing factor 3a, subunit 3, 60kDa
chr19_+_10843244 0.455 NM_199141
CARM1
coactivator-associated arginine methyltransferase 1
chr1_-_243093833 0.453 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr8_-_91065961 0.443 NBN
nibrin
chr11_-_62218759 0.442 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr16_-_2330594 0.441 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr16_+_29725597 0.439


chr5_-_140978751 0.436 NM_001079812
NM_005219
DIAPH1

diaphanous homolog 1 (Drosophila)

chr2_-_131966416 0.435 MZT2A
mitotic spindle organizing protein 2A
chr16_+_29734785 0.433 C16orf53
chromosome 16 open reading frame 53
chr17_-_38087366 0.415 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr1_+_145180914 0.413 NM_004284
CHD1L
chromodomain helicase DNA binding protein 1-like
chr1_+_145180959 0.403 CHD1L
chromodomain helicase DNA binding protein 1-like
chr17_+_35390711 0.399 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr1_+_28717349 0.398 RCC1
regulator of chromosome condensation 1
chr12_-_52001610 0.398 NM_001173466
NM_015665
AAAS

achalasia, adrenocortical insufficiency, alacrimia

chr1_-_6537171 0.397 NM_024654
NOL9
nucleolar protein 9
chr15_+_89246780 0.396 MAN2A2
mannosidase, alpha, class 2A, member 2
chr1_-_200396328 0.389 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr17_-_31964723 0.389 MYO19
myosin XIX
chr6_-_97452416 0.389 NDUFAF4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr16_+_29725311 0.385 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr11_+_64705261 0.383 NM_001198868
CAPN1
calpain 1, (mu/I) large subunit
chr1_-_210275402 0.380 NM_015434
INTS7
integrator complex subunit 7
chrX_+_11686629 0.377 NM_001193270
MSL3
male-specific lethal 3 homolog (Drosophila)
chr15_-_39412032 0.375 NM_007280
OIP5
Opa interacting protein 5
chr19_-_46550788 0.375 TGFB1
transforming growth factor, beta 1
chr7_+_98314020 0.368 NM_003496
TRRAP
transformation/transcription domain-associated protein
chr1_+_184611512 0.364 NM_001164245
NM_001164246
NM_017847
C1orf27


chromosome 1 open reading frame 27


chr11_+_66790517 0.360 ADRBK1
adrenergic, beta, receptor kinase 1
chr6_+_138230045 0.356 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr11_-_36488343 0.356 NM_004620
NM_145803
TRAF6

TNF receptor-associated factor 6

chr16_+_29734990 0.356 NM_024516
C16orf53
chromosome 16 open reading frame 53
chr6_-_119512035 0.354 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr12_+_56406296 0.353 LOC100130776
hypothetical LOC100130776
chr12_-_52001515 0.352 AAAS
achalasia, adrenocortical insufficiency, alacrimia
chr19_-_19615452 0.348 NM_016573
GMIP
GEM interacting protein
chr17_-_58877276 0.347 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr1_+_153232685 0.347 NM_018655
LENEP
lens epithelial protein
chr11_+_46325457 0.346 NM_003646
DGKZ
diacylglycerol kinase, zeta
chr7_-_38355949 0.345


chr19_+_10843369 0.344 CARM1
coactivator-associated arginine methyltransferase 1
chr19_-_53841064 0.344 NM_001217
CA11
carbonic anhydrase XI
chr16_-_65422365 0.341 NM_001018159
NM_001018160
NM_003905
NAE1


NEDD8 activating enzyme E1 subunit 1


chr22_+_20880159 0.339 IGLV6-57
immunoglobulin lambda variable 6-57
chr5_-_140978744 0.337 DIAPH1
diaphanous homolog 1 (Drosophila)
chr9_-_93751900 0.336 NM_004560
ROR2
receptor tyrosine kinase-like orphan receptor 2
chrX_+_11686198 0.335 NM_078628
NM_078629
MSL3

male-specific lethal 3 homolog (Drosophila)

chr1_+_95472298 0.335 NM_001128142
NM_015485
RWDD3

RWD domain containing 3

chr1_-_170679830 0.332 PIGC
phosphatidylinositol glycan anchor biosynthesis, class C
chr6_-_33028790 0.327 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr8_-_74821610 0.326 STAU2
LOC729696
staufen, RNA binding protein, homolog 2 (Drosophila)
hypothetical protein LOC729696
chr11_+_66790740 0.326 ADRBK1
adrenergic, beta, receptor kinase 1
chr10_+_35456095 0.323 CREM
cAMP responsive element modulator
chr22_+_17800018 0.318 NM_003776
MRPL40
mitochondrial ribosomal protein L40
chr1_+_152511708 0.316 HAX1
HCLS1 associated protein X-1
chr1_-_94147574 0.315 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr19_-_19615369 0.314 GMIP
GEM interacting protein
chr1_+_10413361 0.311 APITD1
apoptosis-inducing, TAF9-like domain 1
chr2_-_190893015 0.310 NM_014362
NM_198047
HIBCH

3-hydroxyisobutyryl-CoA hydrolase

chr10_+_92621221 0.310 RPP30
ribonuclease P/MRP 30kDa subunit
chr1_-_94147616 0.309 GCLM
glutamate-cysteine ligase, modifier subunit
chr5_+_132415674 0.309 HSPA4
heat shock 70kDa protein 4
chr12_-_119391918 0.309 NM_003769
SRSF9
serine/arginine-rich splicing factor 9
chr1_+_152511610 0.308 NM_001018837
NM_006118
HAX1

HCLS1 associated protein X-1

chr21_-_43400750 0.308 NM_001025203
NM_001025204
NM_006758
U2AF1


U2 small nuclear RNA auxiliary factor 1


chr1_-_94147537 0.306 GCLM
glutamate-cysteine ligase, modifier subunit
chr4_+_76077229 0.306 NM_015393
PARM1
prostate androgen-regulated mucin-like protein 1
chr11_+_118582231 0.305 CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr17_+_35390632 0.301 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr22_-_49311439 0.300 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr5_+_157103280 0.300 NM_173491
LSM11
LSM11, U7 small nuclear RNA associated
chr1_+_16639822 0.300 NECAP2
NECAP endocytosis associated 2
chr9_-_129993615 0.297 NM_001131016
NM_001131017
NM_001131018
CIZ1


CDKN1A interacting zinc finger protein 1


chr14_-_106064887 0.297 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr21_-_43400672 0.297 U2AF1
U2 small nuclear RNA auxiliary factor 1
chr20_+_60311334 0.296 ADRM1
adhesion regulating molecule 1
chr13_+_32058610 0.294 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr14_-_105681377 0.293 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_+_35390579 0.292 NM_002809
PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr6_-_159160386 0.291 EZR
ezrin
chr1_+_152511756 0.291 HAX1
HCLS1 associated protein X-1
chr14_-_105948734 0.291 LOC100126583
IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr11_+_66790724 0.289 ADRBK1
adrenergic, beta, receptor kinase 1
chr17_+_35390607 0.289 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr16_-_730889 0.289 NM_022493
NARFL
nuclear prelamin A recognition factor-like
chr2_-_190892730 0.287 HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr12_-_54869568 0.286 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr22_+_21094094 0.286


chr17_-_77588844 0.285 NM_001195218
NM_016286
DCXR

dicarbonyl/L-xylulose reductase

chr6_+_41862397 0.284 TOMM6
translocase of outer mitochondrial membrane 6 homolog (yeast)
chr2_+_102456193 0.284 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr11_+_66790465 0.283 NM_001619
ADRBK1
adrenergic, beta, receptor kinase 1
chr13_+_32058651 0.282 PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr6_-_159160387 0.278 EZR
ezrin
chr19_-_6432765 0.277 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr17_+_45911216 0.275 RSAD1
radical S-adenosyl methionine domain containing 1
chr16_+_1143241 0.275 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr3_-_185218311 0.274 NM_001023587
NM_005688
ABCC5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr17_-_18469569 0.274 CCDC144B
coiled-coil domain containing 144B
chr8_-_74821636 0.272 NM_001164380
NM_001164381
NM_001164382
NM_001164383
NM_001164385
NM_014393
STAU2





staufen, RNA binding protein, homolog 2 (Drosophila)





chr1_-_6684465 0.272 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr16_-_88613287 0.271 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr14_-_54438913 0.271 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr17_+_63144500 0.271 NM_015462
NOL11
nucleolar protein 11
chr16_-_65422304 0.269 NAE1
NEDD8 activating enzyme E1 subunit 1
chr18_+_42008063 0.266 C18orf25
chromosome 18 open reading frame 25
chr5_-_140978664 0.262 DIAPH1
diaphanous homolog 1 (Drosophila)
chr1_+_16639805 0.262 NECAP2
NECAP endocytosis associated 2
chr16_+_67902751 0.262 NM_013245
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr2_+_233927892 0.262 DGKD
diacylglycerol kinase, delta 130kDa
chr17_+_35390641 0.261 PSMD3
proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
chr1_-_6684426 0.260 DNAJC11
DnaJ (Hsp40) homolog, subfamily C, member 11
chr19_+_43585668 0.259 FAM98C
family with sequence similarity 98, member C
chr11_+_66790505 0.259 ADRBK1
adrenergic, beta, receptor kinase 1
chr22_-_49311722 0.257 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr20_+_60311443 0.257 ADRM1
adhesion regulating molecule 1
chr4_-_1980500 0.256 WHSC2
Wolf-Hirschhorn syndrome candidate 2
chr14_-_64359565 0.253 NM_000347
NM_001024858
SPTB

spectrin, beta, erythrocytic

chr15_+_48261649 0.253 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr20_+_60311469 0.252 ADRM1
adhesion regulating molecule 1
chr1_-_168310232 0.252 NM_014970
KIFAP3
kinesin-associated protein 3
chr10_+_104144218 0.252 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.47 2.18e-02 GO:0006353 transcription termination, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.51 9.71e-04 GO:0070013 intracellular organelle lumen
1.48 2.79e-03 GO:0043233 organelle lumen
1.49 3.72e-03 GO:0044428 nuclear part
1.47 3.79e-03 GO:0031974 membrane-enclosed lumen
1.24 1.82e-02 GO:0044446 intracellular organelle part
1.11 2.00e-02 GO:0005622 intracellular
1.11 2.16e-02 GO:0044424 intracellular part
2.01 2.64e-02 GO:0030529 ribonucleoprotein complex
1.47 3.32e-02 GO:0031981 nuclear lumen
1.23 4.59e-02 GO:0044422 organelle part

Nothing significant found in function category.