Motif ID: NFATC1..3.p2

Z-value: 1.903


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFATC3chr16_+_66676851-0.829.4e-05Click!
NFATC1chr18_+_75261231-0.457.9e-02Click!


Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_13240987 11.004 EMP1
epithelial membrane protein 1
chr12_+_13240868 9.940 NM_001423
 EMP1
epithelial membrane protein 1
chr2_+_189547377 8.135 COL3A1
collagen, type III, alpha 1
chr2_-_237987579 7.306 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
 COL6A3




collagen, type VI, alpha 3




chr2_+_189547323 7.007 NM_000090
 COL3A1
collagen, type III, alpha 1
chr2_-_237987509 6.936 COL6A3
collagen, type VI, alpha 3
chr2_+_189547358 6.861 COL3A1
collagen, type III, alpha 1
chr2_-_237987554 6.184 COL6A3
collagen, type VI, alpha 3
chr4_+_169654742 5.454 NM_001166108
NM_016081
 PALLD

palladin, cytoskeletal associated protein

chr12_-_90097384 4.964 NM_133503
 DCN
decorin
chr3_+_161040439 4.901 SCHIP1
schwannomin interacting protein 1
chr6_-_169395847 4.499 THBS2
thrombospondin 2
chr6_-_128883125 4.499 NM_002844
NM_001135648
 PTPRK

protein tyrosine phosphatase, receptor type, K

chr22_-_34566210 4.472 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr22_-_34566367 4.471 NM_001031695
NM_001082576
NM_001082577
NM_014309
 RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr8_+_26569709 4.376 DPYSL2
dihydropyrimidinase-like 2
chr6_-_169395972 4.305 NM_003247
 THBS2
thrombospondin 2
chr7_+_115952074 4.142 NM_001753
 CAV1
caveolin 1, caveolae protein, 22kDa
chr17_-_45617899 4.074 COL1A1
collagen, type I, alpha 1
chr22_-_34566276 3.887 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.83 3.43e-06 GO:0007156 homophilic cell adhesion
2.58 1.01e-02 GO:0030198 extracellular matrix organization
2.34 2.13e-03 GO:0043062 extracellular structure organization
1.91 6.04e-03 GO:0016337 cell-cell adhesion
1.70 1.21e-05 GO:0007155 cell adhesion
1.70 1.21e-05 GO:0022610 biological adhesion

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
3.93 4.86e-04 GO:0005581 collagen
2.88 5.12e-03 GO:0031091 platelet alpha granule
1.98 1.58e-04 GO:0005578 proteinaceous extracellular matrix
1.85 4.09e-02 GO:0030141 stored secretory granule
1.80 1.04e-03 GO:0031012 extracellular matrix
1.65 1.60e-08 GO:0044421 extracellular region part
1.61 1.26e-05 GO:0005615 extracellular space
1.56 6.47e-12 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.54 3.95e-02 GO:0005201 extracellular matrix structural constituent
2.08 3.70e-02 GO:0005539 glycosaminoglycan binding
1.76 1.49e-06 GO:0005509 calcium ion binding