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• Activity deltas table
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Motif ID: KLF12.p2

Z-value: 1.934

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_-_45617899	3.073		COL1A1	collagen, type I, alpha 1
chr11_-_2108035	2.921		IGF2	insulin-like growth factor 2 (somatomedin A)
chr5_+_102229612	2.893		PAM	peptidylglycine alpha-amidating monooxygenase
chr9_+_696744	2.698	NM_153186	KANK1	KN motif and ankyrin repeat domains 1
chr9_+_136673464	2.642	NM_000093	COL5A1	collagen, type V, alpha 1
chr20_+_19818209	2.563	NM_018993	RIN2	Ras and Rab interactor 2
chr3_-_101316038	2.419	NM_001042459 NM_182909	FILIP1L	filamin A interacting protein 1-like
chr11_+_116575249	2.362	NM_001001522 NM_003186	TAGLN	transgelin
chr15_-_88148177	2.262		ANPEP	alanyl (membrane) aminopeptidase
chr2_+_36436873	2.157	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr10_-_125841840	2.148	NM_014863 NM_015892	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr5_+_52812165	2.126		FST	follistatin
chr1_-_68470585	2.052	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr5_+_52812236	1.913	NM_006350 NM_013409	FST	follistatin
chr12_-_88270375	1.868	NM_001946 NM_022652	DUSP6	dual specificity phosphatase 6
chr3_-_147361626	1.841		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr10_+_124211353	1.801		HTRA1	HtrA serine peptidase 1
chr12_+_13240987	1.749		EMP1	epithelial membrane protein 1
chr12_-_74711474	1.744		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr6_-_11490487	1.737	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr10_+_124210980	1.662	NM_002775	HTRA1	HtrA serine peptidase 1
chr10_+_104394185	1.628	NM_030912	TRIM8	tripartite motif containing 8
chr8_+_123863224	1.583		ZHX2	zinc fingers and homeoboxes 2
chr5_+_34692239	1.571		RAI14	retinoic acid induced 14
chr15_+_72005864	1.566		LOXL1	lysyl oxidase-like 1
chr1_-_120413798	1.547	NM_024408	NOTCH2	notch 2
chr3_+_108724472	1.543	NM_001142568 NM_020235	BBX	bobby sox homolog (Drosophila)
chr2_-_220144427	1.537		OBSL1	obscurin-like 1
chr17_+_1612056	1.532		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_+_1612031	1.521		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr17_-_1342700	1.514	NM_001080779	MYO1C	myosin IC
chr19_-_54835162	1.509	NM_006270	RRAS	related RAS viral (r-ras) oncogene homolog
chr15_+_72005875	1.501		LOXL1	lysyl oxidase-like 1
chr17_+_1612092	1.492		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr12_-_88270128	1.458		DUSP6	dual specificity phosphatase 6
chr4_-_57671273	1.440	NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr11_-_116692128	1.427	NM_012104 NM_138971 NM_138972 NM_138973	BACE1	beta-site APP-cleaving enzyme 1
chr9_+_115303527	1.426	NM_130795	RGS3	regulator of G-protein signaling 3
chr20_+_19863716	1.425		RIN2	Ras and Rab interactor 2
chr12_-_88270369	1.423		DUSP6	dual specificity phosphatase 6
chr12_+_77782579	1.422	NM_005639	SYT1	synaptotagmin I
chr11_-_2116501	1.415		IGF2	insulin-like growth factor 2 (somatomedin A)
chr6_+_7486891	1.396		DSP	desmoplakin
chr12_+_77782648	1.379		SYT1	synaptotagmin I
chr6_-_128883125	1.370	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr13_-_95503566	1.363	NM_020121	UGGT2	UDP-glucose glycoprotein glucosyltransferase 2
chr5_+_34692352	1.347	NM_001145520	RAI14	retinoic acid induced 14
chr6_+_7486836	1.340		DSP	desmoplakin
chr1_-_33613729	1.330	NM_198040	PHC2	polyhomeotic homolog 2 (Drosophila)
chr22_-_41353575	1.316		CYB5R3	cytochrome b5 reductase 3
chr22_-_41372620	1.293		CYB5R3	cytochrome b5 reductase 3
chrX_-_10495476	1.291	NM_001193278 NM_001193279 NM_001193280 NM_001193281	MID1	midline 1 (Opitz/BBB syndrome)
chr17_+_67628749	1.278	NM_000346	SOX9	SRY (sex determining region Y)-box 9
chr12_+_77782719	1.275		SYT1	synaptotagmin I
chr6_+_7486862	1.260	NM_001008844 NM_004415	DSP	desmoplakin
chr9_-_116920232	1.258	NM_002160	TNC	tenascin C
chr2_-_220144254	1.251		OBSL1	obscurin-like 1
chr3_-_130761967	1.250		PLXND1	plexin D1
chr2_-_161058120	1.246		RBMS1	RNA binding motif, single stranded interacting protein 1
chr2_-_189752575	1.236	NM_000393	COL5A2	collagen, type V, alpha 2
chr5_+_34692124	1.226	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chrX_+_135079120	1.222	NM_001159704	FHL1	four and a half LIM domains 1
chr16_-_66535457	1.218	NM_000229	LCAT	lecithin-cholesterol acyltransferase
chr3_-_151171576	1.215		PFN2	profilin 2
chr1_+_31823097	1.214		TINAGL1	tubulointerstitial nephritis antigen-like 1
chr8_-_119192985	1.199	NM_000127	EXT1	exostosin 1
chr16_+_81218074	1.192	NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr11_-_114593838	1.191		CADM1	cell adhesion molecule 1
chr2_+_24126087	1.187	NM_004116 NM_054033	FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr2_+_24126140	1.185		FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr17_+_1611983	1.181	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_+_38389799	1.156		LRP3	low density lipoprotein receptor-related protein 3
chr10_+_53744043	1.153	NM_012242	DKK1	dickkopf homolog 1 (Xenopus laevis)
chr8_+_123863075	1.135	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr2_+_69822609	1.130	NM_001153	ANXA4	annexin A4
chrX_+_135079461	1.130	NM_001167819	FHL1	four and a half LIM domains 1
chr14_+_85066207	1.120	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr4_-_141896920	1.119	NM_015130	TBC1D9	TBC1 domain family, member 9 (with GRAM domain)
chr2_+_69822754	1.105		ANXA4	annexin A4
chr4_-_57671112	1.103		IGFBP7	insulin-like growth factor binding protein 7
chr1_-_120413542	1.092		NOTCH2	notch 2
chr20_+_34603311	1.091		MYL9	myosin, light chain 9, regulatory
chr15_-_70288071	1.080		PKM2	pyruvate kinase, muscle
chr22_-_41372920	1.079	NM_001129819 NM_001171661 NM_007326	CYB5R3	cytochrome b5 reductase 3
chr6_+_21701942	1.078	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr12_+_12935222	1.073	NM_003979	GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr3_-_78749633	1.072		ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr22_+_29817315	1.069		SMTN	smoothelin
chr15_-_88148538	1.067		ANPEP	alanyl (membrane) aminopeptidase
chr17_+_76133337	1.059		RPTOR	regulatory associated protein of MTOR, complex 1
chr11_-_11986704	1.059	NM_001018057	DKK3	dickkopf homolog 3 (Xenopus laevis)
chr5_+_140871107	1.054
chr11_+_66827494	1.051	NM_017857	SSH3	slingshot homolog 3 (Drosophila)
chrX_+_151837064	1.050	NM_001178113	ZNF185	zinc finger protein 185 (LIM domain)
chr11_-_2116048	1.044		IGF2	insulin-like growth factor 2 (somatomedin A)
chr1_-_95165037	1.044		CNN3	calponin 3, acidic
chr3_-_147361465	1.043		PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr8_-_17624304	1.038	NM_001166393	MTUS1	microtubule associated tumor suppressor 1
chr12_-_6321241	1.036		TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A
chr17_-_7248137	1.024	NM_152766	C17orf61-PLSCR3 C17orf61	C17orf61-PLSCR3 read-through transcript chromosome 17 open reading frame 61
chr7_-_107430566	1.018	NM_002291	LAMB1	laminin, beta 1
chr5_+_140790365	1.016		PCDHGA12	protocadherin gamma subfamily A, 12
chr11_+_66827563	1.015		SSH3	slingshot homolog 3 (Drosophila)
chr7_-_94123362	1.013		SGCE	sarcoglycan, epsilon
chr4_+_169989680	1.011	NM_001166110	PALLD	palladin, cytoskeletal associated protein
chr12_+_6923441	1.001	NM_138425	C12orf57	chromosome 12 open reading frame 57
chr1_+_143920424	1.000	NM_203458	NOTCH2NL	notch 2 N-terminal like
chr2_-_222145240	0.992	NM_004438	EPHA4	EPH receptor A4
chr5_+_140790310	0.986	NM_003735 NM_032094	PCDHGA12	protocadherin gamma subfamily A, 12
chr3_+_160269734	0.977	NM_001197113 NM_001197114 NM_001042705 NM_001042706 NM_001197100	IQCJ-SCHIP1 IQCJ	IQCJ-SCHIP1 readthrough IQ motif containing J
chr22_+_29817218	0.977		SMTN	smoothelin
chr7_-_94123308	0.975		SGCE	sarcoglycan, epsilon
chr9_-_98421894	0.961	NM_003671 NM_033331	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr5_-_73973004	0.950	NM_003633	ENC1	ectodermal-neural cortex 1 (with BTB-like domain)
chr14_-_22891263	0.949	NM_020372	SLC22A17	solute carrier family 22, member 17
chr16_+_54072969	0.947	NM_001127891	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_-_8695974	0.946		ST5	suppression of tumorigenicity 5
chr19_+_46416938	0.934	NM_001699 NM_021913	AXL	AXL receptor tyrosine kinase
chr8_-_27524744	0.934	NM_203339	CLU	clusterin
chr9_+_115367122	0.931	NM_134427	RGS3	regulator of G-protein signaling 3
chr14_-_52487386	0.927		FERMT2	fermitin family member 2
chr12_-_51298599	0.927	NM_175068	KRT73	keratin 73
chr7_-_94123413	0.923	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr14_+_61231795	0.921	NM_001530 NM_181054	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr1_-_201321711	0.921		MYOG	myogenin (myogenic factor 4)
chr5_+_140790510	0.918		PCDHGA12	protocadherin gamma subfamily A, 12
chr11_-_65841077	0.913	NM_020404	CD248	CD248 molecule, endosialin
chr3_-_51971915	0.903	NM_033010	PCBP4	poly(rC) binding protein 4
chrX_+_54852217	0.902	NM_201222	MAGED2	melanoma antigen family D, 2
chr17_-_38427957	0.897	NM_006373	VAT1	vesicle amine transport protein 1 homolog (T. californica)
chr5_-_125958503	0.896	NM_001182	ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr15_+_72006015	0.892		LOXL1	lysyl oxidase-like 1
chr8_-_27525084	0.888	NM_001171138	CLU	clusterin
chr8_-_49996353	0.884	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr15_+_61123327	0.883		TPM1	tropomyosin 1 (alpha)
chr16_-_4502980	0.879		C16orf5	chromosome 16 open reading frame 5
chr1_+_63831479	0.878	NM_002633	PGM1	phosphoglucomutase 1
chr6_-_134680888	0.874	NM_001143676	SGK1	serum/glucocorticoid regulated kinase 1
chr20_-_49818306	0.868	NM_006045	ATP9A	ATPase, class II, type 9A
chr14_-_52487022	0.866		FERMT2	fermitin family member 2
chr5_-_127901633	0.862	NM_001999	FBN2	fibrillin 2
chr20_-_17589122	0.862		RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chr11_-_2116360	0.860		IGF2	insulin-like growth factor 2 (somatomedin A)
chr22_+_31527678	0.858		TIMP3	TIMP metallopeptidase inhibitor 3
chr14_-_52487558	0.856	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chr8_+_56177567	0.856	NM_052898	XKR4	XK, Kell blood group complex subunit-related family, member 4
chr2_-_220116508	0.855	NM_024536	CHPF	chondroitin polymerizing factor
chr4_-_81213207	0.851
chr6_+_32003380	0.850		C2	complement component 2
chr17_+_35853177	0.848	NM_001552	IGFBP4	insulin-like growth factor binding protein 4
chr15_+_72005847	0.845		LOXL1	lysyl oxidase-like 1
chr11_-_62070867	0.845	NM_001620 NM_024060	AHNAK	AHNAK nucleoprotein
chr3_-_51968995	0.843		PCBP4	poly(rC) binding protein 4
chr17_-_38427928	0.839		VAT1	vesicle amine transport protein 1 homolog (T. californica)
chr16_+_31390567	0.838	NM_001042454 NM_001164719	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr10_-_90702490	0.831	NM_001613	ACTA2	actin, alpha 2, smooth muscle, aorta
chr10_+_123913094	0.829	NM_006997 NM_206860	TACC2	transforming, acidic coiled-coil containing protein 2
chr6_+_89847183	0.828		PNRC1	proline-rich nuclear receptor coactivator 1
chr3_+_137224266	0.828	NM_181897	PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha
chr3_+_51397756	0.826		MANF	mesencephalic astrocyte-derived neurotrophic factor
chr10_-_17699371	0.825	NM_014241	PTPLA	protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr12_-_79855618	0.824	NM_004664	LIN7A	lin-7 homolog A (C. elegans)
chr16_+_54070302	0.823	NM_004530	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr16_-_4106022	0.819		ADCY9	adenylate cyclase 9
chr15_+_72005839	0.815	NM_005576	LOXL1	lysyl oxidase-like 1
chr17_-_38427853	0.814		VAT1	vesicle amine transport protein 1 homolog (T. californica)
chr1_-_95165089	0.808	NM_001839	CNN3	calponin 3, acidic
chr1_-_199742841	0.807		CSRP1	cysteine and glycine-rich protein 1
chr9_-_34627786	0.805		SIGMAR1	sigma non-opioid intracellular receptor 1
chr3_+_33293915	0.805	NM_012157 NM_001171713	FBXL2	F-box and leucine-rich repeat protein 2
chr10_-_105604942	0.800	NM_014631	SH3PXD2A	SH3 and PX domains 2A
chr12_+_7038240	0.800	NM_001734 NM_201442	C1S	complement component 1, s subcomponent
chr20_-_49818268	0.798		ATP9A	ATPase, class II, type 9A
chr4_+_6627816	0.798		MAN2B2	mannosidase, alpha, class 2B, member 2
chr16_-_88084387	0.793	NM_013275	ANKRD11	ankyrin repeat domain 11
chr12_-_74711642	0.792	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr1_-_151804929	0.785	NM_005978	S100A2	S100 calcium binding protein A2
chr4_-_54625463	0.784		CHIC2	cysteine-rich hydrophobic domain 2
chr5_-_95323180	0.784		ELL2	elongation factor, RNA polymerase II, 2
chr6_+_89847019	0.783	NM_006813	PNRC1	proline-rich nuclear receptor coactivator 1
chr4_+_30330963	0.783	NM_001173523 NM_002589 NM_032456 NM_032457	PCDH7	protocadherin 7
chr13_+_113574925	0.781	NM_001143945	GAS6	growth arrest-specific 6
chr6_-_33375106	0.774	NM_004761	RGL2	ral guanine nucleotide dissociation stimulator-like 2
chr22_+_31527744	0.769		TIMP3	TIMP metallopeptidase inhibitor 3
chr7_-_27102049	0.764	NM_005522 NM_153620	HOXA1	homeobox A1
chr14_-_93926679	0.760	NM_001002235 NM_001002236 NM_001127700 NM_001127701 NM_001127702 NM_001127703 NM_001127704 NM_001127705 NM_001127706 NM_001127707	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_+_6627801	0.759	NM_015274	MAN2B2	mannosidase, alpha, class 2B, member 2
chr20_+_34603290	0.759	NM_006097 NM_181526	MYL9	myosin, light chain 9, regulatory
chr17_+_4784524	0.758		RNF167	ring finger protein 167
chr1_-_207892296	0.757	NM_001127641	LAMB3	laminin, beta 3
chr3_-_151171190	0.750	NM_002628 NM_053024	PFN2	profilin 2
chr3_-_87122936	0.745	NM_016206	VGLL3	vestigial like 3 (Drosophila)
chr7_+_94123556	0.738	NM_001040152 NM_001184961 NM_001184962 NM_015068	PEG10	paternally expressed 10
chr20_-_17610828	0.735	NM_001042576 NM_004587	RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chr1_+_167342149	0.734		ATP1B1	ATPase, Na+/K+ transporting, beta 1 polypeptide
chr8_-_67687980	0.733	NM_001080416 NM_001144755	MYBL1 LOC645895	v-myb myeloblastosis viral oncogene homolog (avian)-like 1 hypothetical LOC645895
chr10_-_90740935	0.733	NM_001141945	ACTA2	actin, alpha 2, smooth muscle, aorta
chr3_-_49370682	0.730		GPX1	glutathione peroxidase 1
chr9_+_19039355	0.729	NM_006570	RRAGA	Ras-related GTP binding A
chr9_-_34627752	0.728	NM_005866 NM_147157	SIGMAR1	sigma non-opioid intracellular receptor 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.27	1.84e-09	GO:0048731	system development
1.25	2.66e-09	GO:0048856	anatomical structure development
1.36	3.81e-08	GO:0009653	anatomical structure morphogenesis
1.22	6.97e-08	GO:0007275	multicellular organismal development
1.64	1.65e-07	GO:0072358	cardiovascular system development
1.64	1.65e-07	GO:0072359	circulatory system development
1.81	4.06e-07	GO:0001944	vasculature development
1.16	6.85e-07	GO:0032501	multicellular organismal process
1.19	1.75e-06	GO:0032502	developmental process
1.28	2.52e-06	GO:0048869	cellular developmental process
1.28	4.25e-06	GO:0030154	cell differentiation
1.57	1.29e-05	GO:0000904	cell morphogenesis involved in differentiation
1.49	2.37e-05	GO:0032989	cellular component morphogenesis
1.75	2.69e-05	GO:0001568	blood vessel development
1.30	6.28e-05	GO:0007399	nervous system development
1.49	6.32e-05	GO:0000902	cell morphogenesis
1.79	1.13e-04	GO:0048514	blood vessel morphogenesis
1.69	1.18e-04	GO:0030029	actin filament-based process
1.52	1.65e-04	GO:0048858	cell projection morphogenesis
1.38	1.74e-04	GO:0022008	neurogenesis
1.38	1.77e-04	GO:0048468	cell development
3.61	2.59e-04	GO:0003158	endothelium development
1.51	3.22e-04	GO:0032990	cell part morphogenesis
1.53	5.66e-04	GO:0048812	neuron projection morphogenesis
1.54	5.76e-04	GO:0007409	axonogenesis
1.37	7.52e-04	GO:0048699	generation of neurons
1.52	8.32e-04	GO:0048667	cell morphogenesis involved in neuron differentiation
1.37	9.26e-04	GO:0009888	tissue development
1.50	1.91e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.58	1.95e-03	GO:0007411	axon guidance
1.42	2.04e-03	GO:0030030	cell projection organization
3.51	3.37e-03	GO:0045446	endothelial cell differentiation
1.27	3.77e-03	GO:0009966	regulation of signal transduction
1.39	5.56e-03	GO:0030182	neuron differentiation
1.84	8.72e-03	GO:0034330	cell junction organization
1.22	9.10e-03	GO:0048513	organ development
1.57	1.08e-02	GO:0022603	regulation of anatomical structure morphogenesis
1.30	1.10e-02	GO:0007154	cell communication
1.44	1.15e-02	GO:0031175	neuron projection development
1.59	1.15e-02	GO:0061061	muscle structure development
1.63	1.31e-02	GO:0030036	actin cytoskeleton organization
1.32	1.59e-02	GO:0040011	locomotion
1.73	1.65e-02	GO:0006936	muscle contraction
1.69	1.82e-02	GO:0003012	muscle system process
1.35	1.90e-02	GO:0016192	vesicle-mediated transport
1.73	2.76e-02	GO:0001525	angiogenesis
1.33	3.34e-02	GO:2000026	regulation of multicellular organismal development
1.39	3.81e-02	GO:0048666	neuron development
1.82	3.82e-02	GO:0034329	cell junction assembly
2.74	4.96e-02	GO:0007044	cell-substrate junction assembly

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	7.71e-05	GO:0071944	cell periphery
1.16	1.21e-04	GO:0005886	plasma membrane
1.09	1.36e-03	GO:0016020	membrane
1.51	8.26e-03	GO:0015629	actin cytoskeleton
1.58	9.93e-03	GO:0016323	basolateral plasma membrane
2.64	1.34e-02	GO:0032432	actin filament bundle
2.67	1.94e-02	GO:0001725	stress fiber
1.85	2.41e-02	GO:0005925	focal adhesion
3.69	2.58e-02	GO:0005583	fibrillar collagen
1.62	3.21e-02	GO:0031252	cell leading edge
1.16	4.19e-02	GO:0044459	plasma membrane part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.61	2.40e-04	GO:0003779	actin binding
1.42	2.58e-03	GO:0008092	cytoskeletal protein binding
3.69	4.81e-02	GO:0048407	platelet-derived growth factor binding