Motif ID: HAND1,2.p2

Z-value: 1.312


Transcription factors associated with HAND1,2.p2:

Gene SymbolEntrez IDGene Name
HAND1 9421 heart and neural crest derivatives expressed 1
HAND2 9464 heart and neural crest derivatives expressed 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HAND1chr5_-_153838013-0.116.9e-01Click!
HAND2chr4_-_1746879310.048.9e-01Click!


Activity profile for motif HAND1,2.p2.

activity profile for motif HAND1,2.p2


Sorted Z-values histogram for motif HAND1,2.p2

Sorted Z-values for motif HAND1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HAND1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_-_105845570 5.269 IGHA1
immunoglobulin heavy constant alpha 1
chr5_-_149772563 3.925 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr6_+_6533932 2.802 NM_004271
 LY86
lymphocyte antigen 86
chr14_-_106249999 2.775 IGHA1
immunoglobulin heavy constant alpha 1
chr22_+_21053972 2.712


chr19_+_55614006 2.651 NM_003121
 SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr5_-_149772469 2.572 NM_001025159
NM_004355
NM_001025158
 CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr14_-_106241445 2.394 IGHV4-31
IGHV1-69
IGHA1
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 1-69
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr1_-_158948176 1.988 NM_001778
 CD48
CD48 molecule
chr11_+_22652894 1.870 NM_005256
 GAS2
growth arrest-specific 2
chr4_-_40326603 1.835 NM_001098634
 RBM47
RNA binding motif protein 47
chr7_+_99654806 1.818 NM_024070
 PVRIG
poliovirus receptor related immunoglobulin domain containing
chr14_+_75058591 1.684 BATF
basic leucine zipper transcription factor, ATF-like
chr14_+_75058518 1.622 NM_006399
 BATF
basic leucine zipper transcription factor, ATF-like
chr1_+_26517045 1.602 CD52
CD52 molecule
chrX_+_128741562 1.580 NM_018990
 SASH3
SAM and SH3 domain containing 3
chrX_+_128741578 1.550 SASH3
SAM and SH3 domain containing 3
chr12_-_51887318 1.535 ITGB7
integrin, beta 7
chr11_+_22646229 1.439 NM_177553
 GAS2
growth arrest-specific 2
chr13_+_30207690 1.418 ALOX5AP
arachidonate 5-lipoxygenase-activating protein

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
12.52 3.35e-02 GO:0001891 phagocytic cup
1.49 3.68e-02 GO:0005887 integral to plasma membrane
1.48 3.40e-03 GO:0005576 extracellular region
1.46 4.62e-04 GO:0044459 plasma membrane part
1.30 4.55e-03 GO:0071944 cell periphery
1.28 1.15e-02 GO:0005886 plasma membrane
1.20 3.35e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
4.69 1.60e-02 GO:0003823 antigen binding
3.98 1.89e-04 GO:0005179 hormone activity