Motif ID: STAT2,4,6.p2

Z-value: 1.819


Transcription factors associated with STAT2,4,6.p2:

Gene SymbolEntrez IDGene Name
STAT2 6773 signal transducer and activator of transcription 2, 113kDa
STAT4 6775 signal transducer and activator of transcription 4
STAT6 6778 signal transducer and activator of transcription 6, interleukin-4 induced

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT4chr2_-_191723951,
chr2_-_191724169		-0.467.2e-02Click!
STAT2chr12_-_550401830.282.9e-01Click!
STAT6chr12_-_557914430.029.4e-01Click!


Activity profile for motif STAT2,4,6.p2.

activity profile for motif STAT2,4,6.p2


Sorted Z-values histogram for motif STAT2,4,6.p2

Sorted Z-values for motif STAT2,4,6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT2,4,6.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_9159789 5.389 NM_000014
 A2M
alpha-2-macroglobulin
chr14_+_94148466 5.102 NM_001085
 SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr3_-_188945921 4.005 BCL6
B-cell CLL/lymphoma 6
chr3_-_188946168 3.841 NM_001706
 BCL6
B-cell CLL/lymphoma 6
chr8_-_27524744 3.385 NM_203339
 CLU
clusterin
chr8_-_27525084 3.304 NM_001171138
 CLU
clusterin
chr12_-_9159780 3.070 A2M
alpha-2-macroglobulin
chr3_+_187813553 2.884 AHSG
alpha-2-HS-glycoprotein
chr5_+_71538456 2.792 MAP1B
microtubule-associated protein 1B
chr3_+_187813405 2.723 AHSG
alpha-2-HS-glycoprotein
chr3_+_187813538 2.705 NM_001622
 AHSG
alpha-2-HS-glycoprotein
chr17_+_1592879 2.660 NM_000934
NM_001165921
 SERPINF2

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

chr1_-_228916486 2.326 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_228916958 2.303 NM_000029
 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr12_-_7136189 2.246 C1R
complement component 1, r subcomponent
chr12_-_7136147 2.242 NM_001733
 C1R
complement component 1, r subcomponent
chr1_-_228916470 2.228 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr12_-_9159742 2.163 A2M
alpha-2-macroglobulin
chr8_-_27528105 2.149 CLU
clusterin
chr17_+_1593040 2.137 NM_001165920
 SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.63 1.07e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.19 4.99e-02 GO:0005924 cell-substrate adherens junction

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.18 4.59e-02 GO:0043169 cation binding