Motif ID: ETS1,2.p2

Z-value: 1.556


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ETS1chr11_-_127897098-0.224.1e-01Click!
ETS2chr21_+_39099717-0.126.6e-01Click!


Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_31003260 2.770 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr1_-_31003181 2.575 LAPTM5
lysosomal protein transmembrane 5
chr2_-_109728958 2.118 NM_144710
NM_178584
SEPT10

septin 10

chr19_+_54530546 2.050 CD37
CD37 molecule
chr2_+_33514896 1.890 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr12_-_47604930 1.838 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr12_-_6103945 1.803 NM_000552
VWF
von Willebrand factor
chr9_+_115396020 1.756 NM_144489
RGS3
regulator of G-protein signaling 3
chr19_+_54530512 1.679 CD37
CD37 molecule
chr10_-_98021144 1.676 NM_001114094
NM_013314
BLNK

B-cell linker

chr19_+_54530497 1.632 CD37
CD37 molecule
chr19_+_54530485 1.631 NM_001040031
NM_001774
CD37

CD37 molecule

chr2_-_109728693 1.625 SEPT10
septin 10
chr21_-_45165249 1.519 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_11490487 1.496 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr19_+_54530458 1.482 CD37
CD37 molecule
chr21_-_45165302 1.479 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_149772469 1.442 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr14_-_106184988 1.414 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_149960612 1.377 NM_024711
GIMAP6
GTPase, IMAP family member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 31 entries
enrichment   p-value GO term description
2.25 3.46e-03 GO:0035023 regulation of Rho protein signal transduction
2.23 4.72e-03 GO:0050851 antigen receptor-mediated signaling pathway
2.05 4.44e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.04 3.53e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.92 4.65e-02 GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
1.91 1.14e-02 GO:0050900 leukocyte migration
1.84 1.95e-03 GO:0051249 regulation of lymphocyte activation
1.82 3.90e-02 GO:0051251 positive regulation of lymphocyte activation
1.78 7.95e-05 GO:0051056 regulation of small GTPase mediated signal transduction
1.78 3.02e-03 GO:0002694 regulation of leukocyte activation
1.78 4.23e-02 GO:0002764 immune response-regulating signaling pathway
1.76 3.33e-03 GO:0050865 regulation of cell activation
1.76 5.50e-03 GO:0045321 leukocyte activation
1.75 2.69e-02 GO:0046578 regulation of Ras protein signal transduction
1.73 1.48e-02 GO:0030168 platelet activation
1.71 7.32e-07 GO:0001775 cell activation
1.59 1.49e-03 GO:0002684 positive regulation of immune system process
1.55 3.63e-02 GO:0044419 interspecies interaction between organisms
1.48 4.94e-02 GO:0009967 positive regulation of signal transduction
1.47 3.73e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.53 7.39e-03 GO:0030695 GTPase regulator activity
1.50 1.42e-02 GO:0060589 nucleoside-triphosphatase regulator activity