Motif ID: SREBF1,2.p2

Z-value: 1.624


Transcription factors associated with SREBF1,2.p2:

Gene SymbolEntrez IDGene Name
SREBF1 6720 sterol regulatory element binding transcription factor 1
SREBF2 6721 sterol regulatory element binding transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SREBF2chr22_+_405590530.572.1e-02Click!
SREBF1chr17_-_17681034,
chr17_-_17681013		-0.562.3e-02Click!


Activity profile for motif SREBF1,2.p2.

activity profile for motif SREBF1,2.p2


Sorted Z-values histogram for motif SREBF1,2.p2

Sorted Z-values for motif SREBF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SREBF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_34107087 4.558 HMOX1
heme oxygenase (decycling) 1
chr1_+_181871830 4.479 NM_015149
 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr20_+_43953428 4.381 CTSA
cathepsin A
chr20_+_43953372 4.368 CTSA
cathepsin A
chr17_-_44043361 4.183 NM_004502
 HOXB7
homeobox B7
chr20_+_43953606 3.888 CTSA
cathepsin A
chr12_-_47604930 3.606 NM_001143781
 FKBP11
FK506 binding protein 11, 19 kDa
chr5_-_150517499 3.397 ANXA6
annexin A6
chr22_+_34107051 3.397 NM_002133
 HMOX1
heme oxygenase (decycling) 1
chr20_+_43953331 3.394 CTSA
cathepsin A
chr15_-_70455355 3.004 NM_000520
 HEXA
hexosaminidase A (alpha polypeptide)
chr1_-_152459506 2.995 C1orf43
chromosome 1 open reading frame 43
chr1_+_11788827 2.967 CLCN6
chloride channel 6
chr17_+_75689985 2.844 GAA
glucosidase, alpha; acid
chr1_-_152459667 2.837 C1orf43
chromosome 1 open reading frame 43
chrX_-_15783015 2.835 NM_003916
 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr7_+_149696792 2.797 NM_001099695
NM_001099696
NM_013400
 REPIN1


replication initiator 1


chr5_-_150517454 2.791 ANXA6
annexin A6
chr16_-_5023934 2.754 NM_016256
 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr16_-_5023914 2.720 NAGPA
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
3.43 2.37e-02 GO:0005798 Golgi-associated vesicle
3.24 1.33e-04 GO:0005765 lysosomal membrane
2.87 1.89e-04 GO:0005774 vacuolar membrane
2.75 4.38e-04 GO:0044437 vacuolar part
2.49 8.19e-06 GO:0000323 lytic vacuole
2.49 8.19e-06 GO:0005764 lysosome
2.43 1.23e-06 GO:0005773 vacuole
1.43 1.03e-02 GO:0005654 nucleoplasm
1.32 7.06e-03 GO:0031974 membrane-enclosed lumen
1.31 1.51e-02 GO:0043233 organelle lumen
1.29 4.98e-02 GO:0070013 intracellular organelle lumen
1.22 2.09e-04 GO:0044446 intracellular organelle part
1.21 1.05e-04 GO:0044444 cytoplasmic part
1.21 3.93e-04 GO:0044422 organelle part
1.15 1.30e-04 GO:0043227 membrane-bounded organelle
1.15 1.45e-04 GO:0043231 intracellular membrane-bounded organelle
1.13 2.50e-04 GO:0043226 organelle
1.13 3.30e-04 GO:0043229 intracellular organelle
1.13 9.19e-03 GO:0005737 cytoplasm
1.10 2.41e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.15 4.29e-03 GO:0005515 protein binding