Motif ID: FEV.p2

Z-value: 1.576


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FEVchr2_-_219558517-0.097.5e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_122862447 3.071 NM_005335
 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr3_-_122862391 2.913 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr8_-_82557956 2.157 NM_001442
 FABP4
fatty acid binding protein 4, adipocyte
chr19_-_44518465 1.971 GMFG
glia maturation factor, gamma
chr17_-_59437782 1.907 NM_000873
 ICAM2
intercellular adhesion molecule 2
chr1_-_79244948 1.894 NM_022159
 ELTD1
EGF, latrophilin and seven transmembrane domain containing 1
chr19_-_44518516 1.865 NM_004877
 GMFG
glia maturation factor, gamma
chr2_+_33514896 1.849 NM_170672
 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_-_101658094 1.648 NM_001159694
NM_016242
 EMCN

endomucin

chr12_-_6103945 1.633 NM_000552
 VWF
von Willebrand factor
chr5_-_54317102 1.513 NM_001135604
NM_007036
 ESM1

endothelial cell-specific molecule 1

chrY_+_2769630 1.310 RPS4Y1
ribosomal protein S4, Y-linked 1
chr11_-_76059435 1.305 NM_001128922
 LRRC32
leucine rich repeat containing 32
chrY_+_2769596 1.274 NM_001008
 RPS4Y1
ribosomal protein S4, Y-linked 1
chr10_+_31650069 1.221 NM_001128128
NM_001174094
 ZEB1

zinc finger E-box binding homeobox 1

chr16_+_1523658 1.191 TMEM204
transmembrane protein 204
chr4_+_91035025 1.185 NM_007351
 MMRN1
multimerin 1
chr21_-_14840506 1.124 NM_022136
 SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr8_+_75066117 1.113 NM_001195797
NM_015364
 LY96

lymphocyte antigen 96

chr17_-_59451662 1.080 NM_001099786
NM_001099787
NM_001099788
NM_001099789
 ICAM2



intercellular adhesion molecule 2




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
2.18 4.56e-05 GO:0050851 antigen receptor-mediated signaling pathway
2.16 1.60e-03 GO:0050852 T cell receptor signaling pathway
2.00 1.22e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.99 1.26e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.76 2.69e-05 GO:0045321 leukocyte activation
1.69 1.04e-02 GO:0002764 immune response-regulating signaling pathway
1.69 1.10e-02 GO:0002757 immune response-activating signal transduction
1.67 1.68e-02 GO:0046649 lymphocyte activation
1.59 1.69e-02 GO:0002694 regulation of leukocyte activation
1.56 2.68e-02 GO:0050865 regulation of cell activation
1.53 1.12e-04 GO:0002684 positive regulation of immune system process
1.50 1.35e-04 GO:0001775 cell activation
1.47 6.60e-03 GO:0016032 viral reproduction
1.43 1.73e-02 GO:0050776 regulation of immune response
1.37 1.41e-05 GO:0032774 RNA biosynthetic process
1.32 8.10e-03 GO:0006351 transcription, DNA-dependent
1.32 4.73e-02 GO:0002682 regulation of immune system process
1.27 2.48e-05 GO:0009059 macromolecule biosynthetic process
1.27 3.05e-05 GO:0034645 cellular macromolecule biosynthetic process
1.27 4.77e-05 GO:0016070 RNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.04 4.95e-03 GO:0071013 catalytic step 2 spliceosome
1.37 1.95e-02 GO:0030529 ribonucleoprotein complex
1.28 4.75e-05 GO:0005654 nucleoplasm
1.20 2.20e-03 GO:0031981 nuclear lumen
1.18 2.62e-03 GO:0043233 organelle lumen
1.18 4.53e-03 GO:0044428 nuclear part
1.17 3.91e-03 GO:0031974 membrane-enclosed lumen
1.16 2.24e-02 GO:0070013 intracellular organelle lumen
1.12 3.14e-02 GO:0032991 macromolecular complex
1.10 4.56e-03 GO:0005634 nucleus
1.10 9.36e-03 GO:0044446 intracellular organelle part
1.10 1.01e-02 GO:0044422 organelle part
1.04 2.13e-02 GO:0005622 intracellular
1.04 2.49e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.15 8.07e-03 GO:0003676 nucleic acid binding
1.07 1.59e-02 GO:0005515 protein binding