Motif ID: SPZ1.p2

Z-value: 1.142


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_132947141 2.107 GPC3
glypican 3
chrX_-_132947290 2.057 NM_001164617
NM_001164618
NM_001164619
NM_004484
 GPC3



glypican 3



chr7_-_103417198 1.664 NM_005045
NM_173054
 RELN

reelin

chr7_+_45894480 1.565 NM_000596
 IGFBP1
insulin-like growth factor binding protein 1
chr6_-_119712596 1.550 NM_005907
 MAN1A1
mannosidase, alpha, class 1A, member 1
chr6_+_37245860 1.414 NM_002648
 PIM1
pim-1 oncogene
chr1_-_32574185 1.395 NM_023009
 MARCKSL1
MARCKS-like 1
chr1_-_159459999 1.371 NM_001643
 APOA2
apolipoprotein A-II
chr13_-_74953873 1.247 NM_014832
 TBC1D4
TBC1 domain family, member 4
chr14_+_100270222 1.103 DLK1
delta-like 1 homolog (Drosophila)
chr12_+_110688728 1.095 NM_000690
 ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr6_+_32090516 1.082 NM_007293
NM_001002029
 C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr12_+_48026955 1.043 DNAJC22
DnaJ (Hsp40) homolog, subfamily C, member 22
chr2_-_20075889 1.035 MATN3
matrilin 3
chr11_-_57039721 0.979 NM_003627
 SLC43A1
solute carrier family 43, member 1
chr16_+_29373365 0.923 NM_001014999
NM_001015000
NM_024044
NM_178044
 SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr2_-_220144254 0.898 OBSL1
obscurin-like 1
chr2_-_20075929 0.892 NM_002381
 MATN3
matrilin 3
chr2_-_174538197 0.887 SP3
Sp3 transcription factor
chrX_-_128485121 0.886 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 41 entries
enrichment   p-value GO term description
1.56 3.24e-03 GO:0018193 peptidyl-amino acid modification
1.52 2.43e-03 GO:0032583 regulation of gene-specific transcription
1.47 1.99e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.46 2.79e-03 GO:0051253 negative regulation of RNA metabolic process
1.45 1.51e-03 GO:0010629 negative regulation of gene expression
1.45 2.38e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.43 7.29e-04 GO:0009890 negative regulation of biosynthetic process
1.43 2.80e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.42 1.96e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.42 3.03e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.42 4.16e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.41 7.85e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.41 8.73e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 4.52e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.39 6.76e-03 GO:0010628 positive regulation of gene expression
1.39 1.22e-02 GO:0051254 positive regulation of RNA metabolic process
1.37 5.11e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 5.15e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.36 1.59e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.34 5.52e-03 GO:0006351 transcription, DNA-dependent

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.37 8.55e-04 GO:0044451 nucleoplasm part
1.28 1.80e-04 GO:0005654 nucleoplasm
1.21 2.57e-03 GO:0031981 nuclear lumen
1.20 5.62e-04 GO:0031974 membrane-enclosed lumen
1.20 7.76e-04 GO:0043233 organelle lumen
1.20 8.38e-04 GO:0070013 intracellular organelle lumen
1.17 1.73e-02 GO:0044428 nuclear part
1.13 3.18e-05 GO:0005634 nucleus
1.08 7.91e-05 GO:0043227 membrane-bounded organelle
1.08 1.02e-04 GO:0043231 intracellular membrane-bounded organelle
1.07 1.02e-03 GO:0043226 organelle
1.06 1.77e-03 GO:0043229 intracellular organelle
1.05 4.85e-04 GO:0044424 intracellular part
1.05 2.13e-03 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.70 1.21e-05 GO:0008134 transcription factor binding
1.70 2.80e-03 GO:0000975 regulatory region DNA binding
1.70 2.80e-03 GO:0001067 regulatory region nucleic acid binding
1.70 2.80e-03 GO:0044212 transcription regulatory region DNA binding
1.68 7.58e-03 GO:0010843 promoter binding
1.58 2.45e-03 GO:0016564 transcription repressor activity
1.55 3.21e-03 GO:0016563 transcription activator activity
1.49 5.16e-06 GO:0043565 sequence-specific DNA binding
1.43 4.43e-07 GO:0001071 nucleic acid binding transcription factor activity
1.43 4.43e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.37 5.62e-05 GO:0030528 transcription regulator activity
1.23 6.58e-05 GO:0003677 DNA binding
1.18 1.16e-04 GO:0003676 nucleic acid binding
1.10 1.17e-05 GO:0005515 protein binding