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• Activity deltas table
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Motif ID: SPI1.p2

Z-value: 3.017

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_26517032	5.730		CD52	CD52 molecule
chr5_-_88215034	5.612	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr1_+_26517045	5.294		CD52	CD52 molecule
chr1_-_31003260	5.272	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr1_-_111544784	5.256	NM_024901	DENND2D	DENN/MADD domain containing 2D
chr12_+_25096755	5.033		LRMP	lymphoid-restricted membrane protein
chr1_-_111544820	5.009		DENND2D	DENN/MADD domain containing 2D
chrX_+_48427103	4.727	NM_000377	WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr14_-_22354457	4.608		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr12_+_25096472	4.314	NM_006152	LRMP	lymphoid-restricted membrane protein
chr17_-_26665220	4.272	NM_006495	EVI2B	ecotropic viral integration site 2B
chr22_+_35586950	4.229	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr14_-_22354389	4.086		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr17_-_26665213	4.077		EVI2B	ecotropic viral integration site 2B
chr17_-_26665144	3.999		EVI2B	ecotropic viral integration site 2B
chr5_+_118719591	3.738		TNFAIP8	tumor necrosis factor, alpha-induced protein 8
chr1_+_111217314	3.694		CD53	CD53 molecule
chr1_+_111217244	3.663	NM_000560	CD53	CD53 molecule
chr17_-_26665194	3.643		EVI2B	ecotropic viral integration site 2B
chr12_-_51887266	3.565	NM_000889	ITGB7	integrin, beta 7
chr14_-_22354851	3.550	NM_001126105 NM_003982	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr2_+_143603439	3.536		ARHGAP15	Rho GTPase activating protein 15
chr2_+_143603368	3.499	NM_018460	ARHGAP15	Rho GTPase activating protein 15
chr14_-_22358752	3.495	NM_001126106	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr6_-_32268267	3.364		GPSM3	G-protein signaling modulator 3
chr22_-_35970230	3.153	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr5_-_88214720	3.086		MEF2C	myocyte enhancer factor 2C
chr1_+_172395277	3.081		RABGAP1L	RAB GTPase activating protein 1-like
chr1_-_31003181	3.053		LAPTM5	lysosomal protein transmembrane 5
chr1_+_159899528	3.041	NM_001002273 NM_001002274 NM_001002275 NM_001190828 NM_004001	FCGR2B FCGR2C	Fc fragment of IgG, low affinity IIb, receptor (CD32) Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr17_-_31441390	3.037	NM_002983	CCL3	chemokine (C-C motif) ligand 3
chr10_-_121292139	3.032	NM_001005339	RGS10	regulator of G-protein signaling 10
chr1_-_181826292	2.999	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr16_-_87570716	2.945	NM_005187	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr22_-_35970133	2.899		RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr3_-_16530132	2.879	NM_015150	RFTN1	raftlin, lipid raft linker 1
chr6_-_32268615	2.865		GPSM3	G-protein signaling modulator 3
chr6_-_33016561	2.856	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr12_-_51887318	2.809		ITGB7	integrin, beta 7
chr10_-_98021144	2.750	NM_001114094 NM_013314	BLNK	B-cell linker
chr18_-_50004770	2.734		MBD2	methyl-CpG binding domain protein 2
chr19_-_7672978	2.699	NM_002002	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)
chr6_+_31648071	2.679	NM_000595	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr7_+_68702252	2.640		AUTS2	autism susceptibility candidate 2
chr6_-_90178630	2.612		RRAGD	Ras-related GTP binding D
chr14_+_20319049	2.611	NM_005615	RNASE6	ribonuclease, RNase A family, k6
chr6_-_90178544	2.605		RRAGD	Ras-related GTP binding D
chr1_-_183210296	2.585	NM_052966	FAM129A	family with sequence similarity 129, member A
chr1_-_25128951	2.578		RUNX3	runt-related transcription factor 3
chr19_+_54530497	2.578		CD37	CD37 molecule
chr19_-_10311262	2.568	NM_002162	ICAM3	intercellular adhesion molecule 3
chr2_-_96174865	2.558	NM_004418	DUSP2	dual specificity phosphatase 2
chr12_+_6930815	2.550		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr2_+_68445821	2.540	NM_002664	PLEK	pleckstrin
chr1_-_181826086	2.414		NCF2	neutrophil cytosolic factor 2
chr7_+_114350144	2.406		MDFIC	MyoD family inhibitor domain containing
chr7_-_86686754	2.396	NM_024315	C7orf23	chromosome 7 open reading frame 23
chr15_+_79304694	2.385	NM_172217	IL16	interleukin 16 (lymphocyte chemoattractant factor)
chr19_-_43800374	2.376	NM_001042600 NM_007181	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr6_+_31647854	2.362	NM_001159740	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr1_-_183210155	2.344		FAM129A	family with sequence similarity 129, member A
chr5_+_49998677	2.338		PARP8	poly (ADP-ribose) polymerase family, member 8
chr6_-_32605898	2.304	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr6_-_31658044	2.272	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr5_+_49998528	2.253	NM_001178056 NM_024615	PARP8	poly (ADP-ribose) polymerase family, member 8
chr1_+_26516967	2.249	NM_001803	CD52	CD52 molecule
chr2_+_68445936	2.246		PLEK	pleckstrin
chr17_-_35975227	2.186	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr7_+_101715137	2.165		SH2B2	SH2B adaptor protein 2
chr3_-_15348811	2.147		SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr7_+_101715110	2.135	NM_020979	SH2B2	SH2B adaptor protein 2
chrX_-_47374187	2.111	NM_001145252	CFP	complement factor properdin
chr6_-_90178685	2.095	NM_021244	RRAGD	Ras-related GTP binding D
chr8_+_56954953	2.092		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr12_+_6926014	2.091		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr22_+_21407066	2.063
chrX_-_47374647	2.042	NM_002621	CFP	complement factor properdin
chr15_+_72861767	2.032		CSK	c-src tyrosine kinase
chr4_-_25473528	2.015	NM_015187	SEL1L3	sel-1 suppressor of lin-12-like 3 (C. elegans)
chr8_+_56954899	2.015	NM_001111097 NM_002350	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr17_+_31455332	1.997	NM_002984	CCL4	chemokine (C-C motif) ligand 4
chr13_-_45654292	1.966		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_31651319	1.943	NM_000594	TNF	tumor necrosis factor
chr8_+_56954946	1.932		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_+_31690957	1.927	NM_004847 NM_001623	AIF1	allograft inflammatory factor 1
chr15_+_72861470	1.890	NM_001127190 NM_004383	CSK	c-src tyrosine kinase
chr1_-_158883666	1.882	NM_003037	SLAMF1	signaling lymphocytic activation molecule family member 1
chr3_-_15349086	1.878	NM_004844	SH3BP5	SH3-domain binding protein 5 (BTK-associated)
chr10_-_27189898	1.876		ABI1	abl-interactor 1
chr11_-_60475558	1.870	NM_016582	SLC15A3	solute carrier family 15, member 3
chr3_-_122862447	1.868	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chrX_-_118711088	1.865		SEPT6	septin 6
chr17_+_31562577	1.813	NM_207007 NM_001001435	CCL4L2 CCL4L1	chemokine (C-C motif) ligand 4-like 2 chemokine (C-C motif) ligand 4-like 1
chr12_+_53177806	1.778		NCKAP1L	NCK-associated protein 1-like
chrX_-_70248022	1.761	NM_000206	IL2RG	interleukin 2 receptor, gamma
chr10_-_27189797	1.750		ABI1	abl-interactor 1
chr12_+_6930694	1.744	NM_002831 NM_080549	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr17_+_62804036	1.743		PITPNC1	phosphatidylinositol transfer protein, cytoplasmic 1
chr17_+_31664143	1.705	NM_207007 NM_001001435	CCL4L2 CCL4L1	chemokine (C-C motif) ligand 4-like 2 chemokine (C-C motif) ligand 4-like 1
chr19_+_54530485	1.705	NM_001040031 NM_001774	CD37	CD37 molecule
chr11_-_58099884	1.697	NM_004811	LPXN	leupaxin
chr7_+_73826244	1.659	NM_000265	NCF1 NCF1B NCF1C	neutrophil cytosolic factor 1 neutrophil cytosolic factor 1B pseudogene neutrophil cytosolic factor 1C pseudogene
chrX_-_135577102	1.651		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_+_53177758	1.649	NM_005337	NCKAP1L	NCK-associated protein 1-like
chr12_+_53177789	1.645		NCKAP1L	NCK-associated protein 1-like
chr19_+_54530546	1.633		CD37	CD37 molecule
chr19_+_54530512	1.632		CD37	CD37 molecule
chr1_+_32512298	1.627	NM_001042771	LCK	lymphocyte-specific protein tyrosine kinase
chr3_-_122862391	1.624		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr12_-_8656705	1.616	NM_020661	AICDA	activation-induced cytidine deaminase
chr7_-_120285364	1.607	NM_012338	TSPAN12	tetraspanin 12
chrX_-_15782803	1.600		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr12_-_50004172	1.592	NM_016293	BIN2	bridging integrator 2
chr1_+_234372454	1.586	NM_003272	GPR137B	G protein-coupled receptor 137B
chr9_+_92603894	1.583		SYK	spleen tyrosine kinase
chrX_+_48427137	1.579		WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chrX_-_78509367	1.572		ITM2A	integral membrane protein 2A
chr16_-_87244896	1.564	NM_000101	CYBA	cytochrome b-245, alpha polypeptide
chr9_+_92603884	1.557		SYK	spleen tyrosine kinase
chr19_+_54530458	1.546		CD37	CD37 molecule
chr6_-_32920689	1.535	NM_004159	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr11_+_128068982	1.531	NM_002017	FLI1	Friend leukemia virus integration 1
chrX_-_78509662	1.513	NM_001171581 NM_004867	ITM2A	integral membrane protein 2A
chr6_-_32920387	1.506		PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr4_-_105631915	1.500	NM_025212	CXXC4	CXXC finger protein 4
chr12_-_50004102	1.499		BIN2	bridging integrator 2
chr2_-_175207521	1.482	NM_003387	WIPF1	WAS/WASL interacting protein family, member 1
chrX_-_15783015	1.479	NM_003916	AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr6_-_32659958	1.475		HLA-DRB1 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 5
chr6_+_12825818	1.470	NM_030948	PHACTR1	phosphatase and actin regulator 1
chr13_-_48005251	1.461	NM_001268	RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr19_-_6432765	1.459	NM_024898	DENND1C	DENN/MADD domain containing 1C
chr1_-_205161821	1.438	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr4_-_91979113	1.431	NM_183049	TMSL3	thymosin-like 3
chr9_+_92603920	1.425		SYK	spleen tyrosine kinase
chr13_-_48005186	1.420		RCBTB2	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr7_-_37454933	1.408	NM_014800	ELMO1	engulfment and cell motility 1
chr10_+_26767698	1.407		APBB1IP	amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr21_-_45165302	1.405	NM_000211	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_154719560	1.405	NM_001130700 NM_015553	IPCEF1	interaction protein for cytohesin exchange factors 1
chr11_+_120828058	1.405	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr11_-_46099531	1.402	NM_001101802 NM_016621	PHF21A	PHD finger protein 21A
chr1_-_142535878	1.390		LOC100286793 FLJ39739	hypothetical LOC100286793 hypothetical FLJ39739
chr21_-_45165204	1.381		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_169657312	1.377		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr21_-_45165249	1.376		ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr17_-_59363352	1.363	NM_000626 NM_001039933 NM_021602	CD79B	CD79b molecule, immunoglobulin-associated beta
chr19_-_60610971	1.356		UBE2S	ubiquitin-conjugating enzyme E2S
chr1_-_27825178	1.347	NM_001042747	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr3_+_48482625	1.345		TREX1	three prime repair exonuclease 1
chr5_-_169657395	1.343	NM_005565	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_-_99536214	1.342	NM_182776	MCM7	minichromosome maintenance complex component 7
chr6_-_137155295	1.342		MAP3K5	mitogen-activated protein kinase kinase kinase 5
chr9_-_125732005	1.341	NM_020946 NM_024820	DENND1A	DENN/MADD domain containing 1A
chr12_+_6930804	1.337		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_-_51198383	1.335		FAF1	Fas (TNFRSF6) associated factor 1
chr10_-_101680645	1.334		DNMBP	dynamin binding protein
chr5_-_169657360	1.324		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_26671488	1.319	NM_005517	HMGN2	high-mobility group nucleosomal binding domain 2
chr6_-_137155222	1.318		MAP3K5	mitogen-activated protein kinase kinase kinase 5
chr2_-_60634271	1.317		BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)
chr1_+_172395170	1.313	NM_014857	RABGAP1L	RAB GTPase activating protein 1-like
chr16_+_27320983	1.308	NM_181078 NM_181079	IL21R	interleukin 21 receptor
chr22_+_35639564	1.300	NM_000395	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_-_181871473	1.295		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr6_-_26164478	1.293	NM_005319	HIST1H1C	histone cluster 1, H1c
chr11_-_66877519	1.287	NM_021173	POLD4	polymerase (DNA-directed), delta 4
chr6_-_32920167	1.287		PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr6_+_31691745	1.282	NM_032955	AIF1	allograft inflammatory factor 1
chrX_-_15782842	1.267		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr1_-_51198328	1.260		FAF1	Fas (TNFRSF6) associated factor 1
chr1_-_32574185	1.258	NM_023009	MARCKSL1	MARCKS-like 1
chr19_-_60610792	1.255		UBE2S	ubiquitin-conjugating enzyme E2S
chr3_+_9809776	1.253	NM_001198780	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa
chr17_+_22982383	1.250		LGALS9	lectin, galactoside-binding, soluble, 9
chr22_-_16637194	1.247		BID	BH3 interacting domain death agonist
chr1_-_166172901	1.246	NM_001143674	BRP44	brain protein 44
chr1_-_149004852	1.246		CTSS	cathepsin S
chr7_+_68701704	1.243	NM_001127231 NM_001127232 NM_015570	AUTS2	autism susceptibility candidate 2
chr11_-_66961709	1.240	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr2_-_74259308	1.240	NM_018221	MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr12_-_47605478	1.238	NM_001143782 NM_016594	FKBP11	FK506 binding protein 11, 19 kDa
chr22_-_16637221	1.237		BID	BH3 interacting domain death agonist
chr12_-_50004208	1.236		BIN2	bridging integrator 2
chr1_+_207995999	1.219	NM_025228	TRAF3IP3	TRAF3 interacting protein 3
chr6_-_32919751	1.218	NM_148919	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr9_+_127549437	1.201	NM_006195	PBX3	pre-B-cell leukemia homeobox 3
chr22_-_16637160	1.198		BID	BH3 interacting domain death agonist
chr1_-_51198052	1.188		FAF1	Fas (TNFRSF6) associated factor 1
chr19_-_8548297	1.183		MYO1F	myosin IF
chrX_-_15782826	1.182
chr19_-_46550788	1.182		TGFB1	transforming growth factor, beta 1
chr9_-_35640852	1.177	NM_014450	SIT1	signaling threshold regulating transmembrane adaptor 1
chr17_+_22982372	1.166		LGALS9	lectin, galactoside-binding, soluble, 9
chr10_+_30763056	1.160		MAP3K8	mitogen-activated protein kinase kinase kinase 8
chr6_-_6265896	1.156	NM_000129	F13A1	coagulation factor XIII, A1 polypeptide
chr1_-_9052170	1.156		SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr6_-_137154859	1.155
chr17_+_22982344	1.153		LGALS9	lectin, galactoside-binding, soluble, 9
chr1_-_181871490	1.152		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.17	5.16e-10	GO:0044260	cellular macromolecule metabolic process
1.25	2.45e-09	GO:0090304	nucleic acid metabolic process
1.21	3.69e-09	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.50	9.25e-08	GO:0006974	response to DNA damage stimulus
1.14	2.86e-07	GO:0043170	macromolecule metabolic process
1.10	4.42e-07	GO:0050794	regulation of cellular process
1.10	1.79e-06	GO:0050789	regulation of biological process
1.09	7.36e-06	GO:0065007	biological regulation
1.16	1.19e-05	GO:0031323	regulation of cellular metabolic process
1.22	4.76e-05	GO:0016070	RNA metabolic process
1.15	1.08e-04	GO:0034641	cellular nitrogen compound metabolic process
1.39	1.18e-04	GO:0006259	DNA metabolic process
1.51	1.32e-04	GO:0006281	DNA repair
1.14	1.89e-04	GO:0019222	regulation of metabolic process
1.15	2.99e-04	GO:0060255	regulation of macromolecule metabolic process
1.14	3.25e-04	GO:0080090	regulation of primary metabolic process
1.22	3.59e-04	GO:0006996	organelle organization
1.31	5.51e-04	GO:0033554	cellular response to stress
1.14	5.57e-04	GO:0006807	nitrogen compound metabolic process
1.56	8.18e-04	GO:0045321	leukocyte activation
1.20	9.66e-04	GO:0010467	gene expression
1.05	1.25e-03	GO:0009987	cellular process
1.61	1.37e-03	GO:0046649	lymphocyte activation
1.23	1.74e-03	GO:0002376	immune system process
1.56	2.42e-03	GO:0071156	regulation of cell cycle arrest
1.37	2.46e-03	GO:0016071	mRNA metabolic process
1.16	2.77e-03	GO:0048522	positive regulation of cellular process
1.56	3.04e-03	GO:0000075	cell cycle checkpoint
1.26	3.72e-03	GO:0007049	cell cycle
1.15	5.21e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.11	5.46e-03	GO:0051716	cellular response to stimulus
1.15	6.19e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.14	6.71e-03	GO:0048518	positive regulation of biological process
1.16	7.07e-03	GO:0010468	regulation of gene expression
1.15	7.19e-03	GO:0031326	regulation of cellular biosynthetic process
1.08	7.49e-03	GO:0044238	primary metabolic process
1.45	8.71e-03	GO:0070647	protein modification by small protein conjugation or removal
1.16	8.78e-03	GO:0048523	negative regulation of cellular process
1.32	9.44e-03	GO:0006396	RNA processing
1.16	9.47e-03	GO:0048519	negative regulation of biological process
1.15	1.03e-02	GO:0009889	regulation of biosynthetic process
1.21	1.30e-02	GO:0035556	intracellular signal transduction
1.32	1.36e-02	GO:0051276	chromosome organization
1.08	1.44e-02	GO:0044237	cellular metabolic process
1.56	1.51e-02	GO:0002757	immune response-activating signal transduction
1.77	1.65e-02	GO:0030098	lymphocyte differentiation
1.27	1.68e-02	GO:0022402	cell cycle process
1.94	1.74e-02	GO:0006302	double-strand break repair
1.34	1.87e-02	GO:0001775	cell activation
1.16	1.96e-02	GO:0051252	regulation of RNA metabolic process
1.44	2.43e-02	GO:0008380	RNA splicing
2.74	2.55e-02	GO:0031572	G2/M transition DNA damage checkpoint
2.11	3.02e-02	GO:0002263	cell activation involved in immune response
2.11	3.02e-02	GO:0002366	leukocyte activation involved in immune response
1.23	3.52e-02	GO:0042981	regulation of apoptosis
1.53	3.53e-02	GO:0002764	immune response-regulating signaling pathway
1.23	3.54e-02	GO:0043067	regulation of programmed cell death
1.46	4.00e-02	GO:0032446	protein modification by small protein conjugation
2.40	4.49e-02	GO:0002285	lymphocyte activation involved in immune response
1.08	4.67e-02	GO:0050896	response to stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.17	1.16e-15	GO:0005634	nucleus
1.27	1.82e-12	GO:0044428	nuclear part
1.27	5.38e-10	GO:0031981	nuclear lumen
1.32	9.07e-10	GO:0005654	nucleoplasm
1.15	2.58e-06	GO:0032991	macromolecular complex
1.05	2.96e-06	GO:0044424	intracellular part
1.05	3.38e-06	GO:0005622	intracellular
1.40	1.14e-05	GO:0005694	chromosome
1.16	1.22e-05	GO:0043234	protein complex
1.17	2.33e-05	GO:0043228	non-membrane-bounded organelle
1.17	2.33e-05	GO:0043232	intracellular non-membrane-bounded organelle
1.18	3.19e-05	GO:0070013	intracellular organelle lumen
1.18	4.08e-05	GO:0031974	membrane-enclosed lumen
1.18	5.28e-05	GO:0043233	organelle lumen
1.18	1.00e-04	GO:0005829	cytosol
1.03	1.05e-04	GO:0005623	cell
1.06	1.16e-04	GO:0043226	organelle
1.06	1.20e-04	GO:0043229	intracellular organelle
1.03	1.32e-04	GO:0044464	cell part
1.38	4.82e-04	GO:0044427	chromosomal part
1.06	4.85e-04	GO:0043227	membrane-bounded organelle
1.06	5.11e-04	GO:0043231	intracellular membrane-bounded organelle
1.29	1.24e-03	GO:0044451	nucleoplasm part
1.09	2.32e-03	GO:0044446	intracellular organelle part
1.08	6.66e-03	GO:0044422	organelle part
1.50	2.72e-02	GO:0030425	dendrite
1.43	4.41e-02	GO:0016604	nuclear body

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.10	2.85e-09	GO:0005515	protein binding
1.32	4.03e-06	GO:0030528	transcription regulator activity
1.35	1.09e-04	GO:0043565	sequence-specific DNA binding
1.14	3.40e-04	GO:0003676	nucleic acid binding
1.18	4.64e-04	GO:0003677	DNA binding
1.46	1.75e-03	GO:0016564	transcription repressor activity
1.58	1.90e-03	GO:0003682	chromatin binding
1.49	1.69e-02	GO:0019787	small conjugating protein ligase activity
1.23	2.44e-02	GO:0001071	nucleic acid binding transcription factor activity
1.23	2.44e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
1.85	2.50e-02	GO:0008094	DNA-dependent ATPase activity