Motif ID: EHF.p2

Z-value: 2.128


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EHFchr11_+_34599227,
chr11_+_34599163
0.165.7e-01Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_181802592 2.384 NM_001042601
NM_133462
TTC14

tetratricopeptide repeat domain 14

chr9_-_137992967 2.219 NM_016172
UBAC1
UBA domain containing 1
chr6_+_134315940 2.119 NM_004865
TBPL1
TBP-like 1
chr7_-_72360722 2.108 NM_001168347
NM_001168348
NM_018044
NM_148956
NSUN5



NOP2/Sun domain family, member 5



chr5_+_140051404 1.987 HARS2
histidyl-tRNA synthetase 2, mitochondrial (putative)
chr1_-_52642646 1.895 NM_001190818
NM_001190819
NM_004153
ORC1


origin recognition complex, subunit 1


chr7_+_74877568 1.883 NSUN5P1
NOP2/Sun domain family, member 5 pseudogene 1
chr3_-_122862447 1.870 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr21_-_32906729 1.618 NM_021254
C21orf59
chromosome 21 open reading frame 59
chr20_+_29598848 1.617 HM13
histocompatibility (minor) 13
chr8_+_56954953 1.610 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr12_+_118590039 1.594 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr11_-_116163904 1.587 ZNF259
zinc finger protein 259
chr1_+_196874759 1.577 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr6_-_31953425 1.547 NM_001178045
SLC44A4
solute carrier family 44, member 4
chr10_+_12278185 1.461 CDC123
cell division cycle 123 homolog (S. cerevisiae)
chr7_-_128482354 1.454 TNPO3
transportin 3
chr8_+_56954899 1.443 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr1_+_32460600 1.432 EIF3I
eukaryotic translation initiation factor 3, subunit I
chr11_-_60430430 1.422 PRPF19
PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 78 entries
enrichment   p-value GO term description
4.10 6.05e-03 GO:0032392 DNA geometric change
3.99 2.50e-02 GO:0032508 DNA duplex unwinding
3.44 3.82e-03 GO:0006626 protein targeting to mitochondrion
3.32 7.49e-03 GO:0072655 establishment of protein localization in mitochondrion
3.20 1.40e-02 GO:0070585 protein localization in mitochondrion
3.10 2.52e-02 GO:0009452 RNA capping
3.06 2.41e-03 GO:0006369 termination of RNA polymerase II transcription
2.95 1.18e-06 GO:0006353 transcription termination, DNA-dependent
2.84 1.09e-03 GO:0050434 positive regulation of viral transcription
2.75 7.48e-06 GO:0022618 ribonucleoprotein complex assembly
2.71 4.28e-04 GO:0006368 transcription elongation from RNA polymerase II promoter
2.67 3.22e-05 GO:0006354 transcription elongation, DNA-dependent
2.64 3.72e-03 GO:0046782 regulation of viral transcription
2.61 1.18e-13 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.61 1.18e-13 GO:0000398 nuclear mRNA splicing, via spliceosome
2.61 4.20e-05 GO:0071826 ribonucleoprotein complex subunit organization
2.57 2.25e-13 GO:0000375 RNA splicing, via transesterification reactions
2.57 2.69e-03 GO:0072594 establishment of protein localization to organelle
2.53 2.72e-12 GO:0022613 ribonucleoprotein complex biogenesis
2.43 2.11e-11 GO:0071843 cellular component biogenesis at cellular level

Gene overrepresentation in compartment category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
2.75 9.78e-03 GO:0015030 Cajal body
2.44 6.60e-04 GO:0071013 catalytic step 2 spliceosome
2.30 4.98e-06 GO:0005681 spliceosomal complex
2.26 3.48e-02 GO:0000502 proteasome complex
2.08 1.83e-03 GO:0016607 nuclear speck
1.90 3.20e-02 GO:0044455 mitochondrial membrane part
1.89 7.00e-05 GO:0016604 nuclear body
1.88 4.78e-12 GO:0030529 ribonucleoprotein complex
1.84 8.14e-11 GO:0005730 nucleolus
1.68 2.38e-02 GO:0000228 nuclear chromosome
1.66 1.66e-03 GO:0005743 mitochondrial inner membrane
1.65 1.06e-27 GO:0031981 nuclear lumen
1.60 1.08e-16 GO:0005654 nucleoplasm
1.59 2.46e-28 GO:0044428 nuclear part
1.59 2.42e-04 GO:0005740 mitochondrial envelope
1.59 4.75e-04 GO:0031966 mitochondrial membrane
1.57 1.72e-06 GO:0044429 mitochondrial part
1.57 1.22e-02 GO:0019866 organelle inner membrane
1.56 7.53e-07 GO:0044451 nucleoplasm part
1.55 1.57e-25 GO:0070013 intracellular organelle lumen

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.34 2.83e-03 GO:0008135 translation factor activity, nucleic acid binding
2.19 2.36e-03 GO:0008026 ATP-dependent helicase activity
2.19 2.36e-03 GO:0070035 purine NTP-dependent helicase activity
2.10 3.09e-02 GO:0015078 hydrogen ion transmembrane transporter activity
1.90 2.99e-02 GO:0004386 helicase activity
1.76 1.24e-14 GO:0003723 RNA binding
1.31 2.40e-11 GO:0003676 nucleic acid binding
1.24 6.00e-04 GO:0000166 nucleotide binding
1.12 2.70e-06 GO:0005515 protein binding
1.05 3.50e-02 GO:0005488 binding