Motif ID: HMGA1,2.p2

Z-value: 0.839


Transcription factors associated with HMGA1,2.p2:

Gene SymbolEntrez IDGene Name
HMGA1 3159 high mobility group AT-hook 1
HMGA2 8091 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMGA1chr6_+_343130070.495.3e-02Click!
HMGA2chr12_+_645044080.165.5e-01Click!


Activity profile for motif HMGA1,2.p2.

activity profile for motif HMGA1,2.p2


Sorted Z-values histogram for motif HMGA1,2.p2

Sorted Z-values for motif HMGA1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMGA1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_5035967 2.001 NM_001135241
 AKR1C1
AKR1C2
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr10_+_4995453 1.847 NM_001353
 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr2_-_188127294 1.772 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr10_+_4995597 1.753 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_-_118670968 1.643 KIAA1598
KIAA1598
chr3_+_143824955 1.594 NM_002670
 PLS1
plastin 1
chr10_+_4995685 1.462 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr10_-_69267774 1.306 NM_021800
NM_201262
 DNAJC12

DnaJ (Hsp40) homolog, subfamily C, member 12

chr2_-_188127430 1.221 NM_001032281
NM_006287
 TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr4_+_74488910 1.138 ALB
albumin
chr2_+_101874809 1.126 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr2_+_234255322 1.036 NM_019077
 UGT1A7
UDP glucuronosyltransferase 1 family, polypeptide A7
chr13_-_45577144 1.026 NM_001872
NM_016413
 CPB2

carboxypeptidase B2 (plasma)

chr14_+_100262916 0.996 DLK1
delta-like 1 homolog (Drosophila)
chr4_+_140806536 0.987 MGST2
microsomal glutathione S-transferase 2
chrX_-_137777382 0.977 NM_001139502
 FGF13
fibroblast growth factor 13
chrX_+_49047068 0.972 NM_001098413
 GAGE10
G antigen 10
chr4_+_74488947 0.971 ALB
albumin
chr4_+_74499651 0.944 ALB
albumin
chr4_+_74496660 0.910 ALB
albumin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.75 7.28e-03 GO:0007608 sensory perception of smell
2.47 3.18e-03 GO:0007606 sensory perception of chemical stimulus

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.50 1.22e-04 GO:0005615 extracellular space
1.42 3.16e-04 GO:0044421 extracellular region part
1.24 2.93e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
7.17 7.94e-04 GO:0005132 interferon-alpha/beta receptor binding
3.09 1.67e-03 GO:0004984 olfactory receptor activity
1.84 2.19e-02 GO:0005125 cytokine activity
1.55 2.60e-02 GO:0004930 G-protein coupled receptor activity