Motif ID: T.p2

Z-value: 0.466


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Tchr6_-_1665021190.591.6e-02Click!


Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_151854619 1.585 NM_004688
NMI
N-myc (and STAT) interactor
chr11_-_110755112 0.829 POU2AF1
POU class 2 associating factor 1
chr1_+_173111306 0.750 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chrX_+_128741562 0.681 NM_018990
SASH3
SAM and SH3 domain containing 3
chr17_+_22982344 0.665 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_22982372 0.659 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_22982319 0.618 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_22982278 0.583 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr17_+_31455332 0.567 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr17_+_22982383 0.557 LGALS9
lectin, galactoside-binding, soluble, 9
chrX_+_128741578 0.522 SASH3
SAM and SH3 domain containing 3
chr2_+_33514896 0.493 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_128468785 0.478 ISOC1
isochorismatase domain containing 1
chr15_+_38648801 0.477 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr22_-_39545197 0.457 NM_006358
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr11_-_33870411 0.443 NM_005574
LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_+_18320822 0.438 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr17_-_20311411 0.399 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr1_+_26609893 0.376 LIN28A
lin-28 homolog A (C. elegans)
chr12_+_112107747 0.366 NM_032848
C12orf52
chromosome 12 open reading frame 52
chr10_-_23043449 0.366 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr6_+_26266311 0.357 NM_021063
NM_138720
HIST1H2BD

histone cluster 1, H2bd

chr6_-_74284522 0.349 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr16_+_75790849 0.339 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr10_+_70517823 0.327 NM_002727
SRGN
serglycin
chr7_+_142723340 0.326 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr7_-_16471817 0.298 NM_015464
SOSTDC1
sclerostin domain containing 1
chr1_+_208008517 0.297 TRAF3IP3
TRAF3 interacting protein 3
chr17_+_31562577 0.267 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr2_-_100088760 0.260 AFF3
AF4/FMR2 family, member 3
chr7_+_107007858 0.259 BCAP29
B-cell receptor-associated protein 29
chr19_-_14121728 0.254 LPHN1
latrophilin 1
chr8_-_38577891 0.252


chr21_-_46528594 0.239 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr15_+_38648783 0.239 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr12_-_121277972 0.236 NM_019887
NM_138929
DIABLO

diablo homolog (Drosophila)

chr18_+_52575442 0.231 WDR7
WD repeat domain 7
chr21_-_14840506 0.230 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr11_-_118405288 0.221 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr1_-_151296611 0.218 NM_005988
SPRR2A
small proline-rich protein 2A
chr2_-_169455167 0.215 NM_020675
SPC25
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr7_-_87687276 0.210 SRI
sorcin
chr4_-_145281237 0.203 NM_002099
GYPA
glycophorin A (MNS blood group)
chr12_-_51360439 0.198 NM_006121
KRT1
keratin 1
chr4_-_73653331 0.191 NM_014243
ADAMTS3
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr15_-_78050515 0.190 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr7_+_99865340 0.190 MEPCE
methylphosphate capping enzyme
chr10_+_70517863 0.190 SRGN
serglycin
chr20_+_42776888 0.186 WISP2
WNT1 inducible signaling pathway protein 2
chr7_-_87687302 0.179 NM_003130
SRI
sorcin
chr14_-_106270497 0.171 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr16_-_66523255 0.169 NM_001907
CTRL
chymotrypsin-like
chr3_+_168936125 0.167 NM_001122752
NM_005025
SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

chr16_+_11966464 0.152 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr11_-_56951628 0.152 NM_017611
SLC43A3
solute carrier family 43, member 3
chr17_-_59327602 0.148 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr2_-_37397669 0.145 NM_005813
PRKD3
protein kinase D3
chr1_-_114925734 0.138 NM_005872
BCAS2
breast carcinoma amplified sequence 2
chr11_-_65869113 0.138 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr20_-_51633042 0.134 NM_006526
ZNF217
zinc finger protein 217
chr4_-_145159889 0.134 NM_002100
GYPB
glycophorin B (MNS blood group)
chr14_-_106184988 0.133 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr15_-_53369261 0.133 NM_183235
RAB27A
RAB27A, member RAS oncogene family
chr14_-_105182025 0.131


chr1_-_114215768 0.130 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr1_-_12830728 0.125 NM_001146181
HNRNPCL1
LOC649330
heterogeneous nuclear ribonucleoprotein C-like 1
heterogeneous nuclear ribonucleoprotein C-like
chr5_-_14706486 0.125


chr6_+_109868897 0.123 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr1_+_39229474 0.123 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr10_+_11087259 0.121 NM_001025077
CELF2
CUGBP, Elav-like family member 2
chr1_+_154389945 0.120 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr12_+_94776836 0.117 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr2_+_176680251 0.113 NM_021192
HOXD11
homeobox D11
chr5_+_179934143 0.112 CNOT6
CCR4-NOT transcription complex, subunit 6
chr4_-_145046109 0.112 NM_002102
NM_198682
GYPE

glycophorin E (MNS blood group)

chr2_-_215711313 0.108 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr1_+_15858950 0.104 NM_006511
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr1_-_153109349 0.101 NM_002249
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr16_-_87244896 0.101 NM_000101
CYBA
cytochrome b-245, alpha polypeptide
chr17_+_77582774 0.101 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr10_-_101680645 0.099 DNMBP
dynamin binding protein
chr1_+_15935395 0.096 NM_207348
SLC25A34
solute carrier family 25, member 34
chr20_+_42777298 0.093 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr1_+_26609819 0.089 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr5_-_138753443 0.087 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr17_+_7402315 0.087 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr10_+_94823636 0.087 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr6_-_31789824 0.087


chr10_-_98935369 0.086 SLIT1
slit homolog 1 (Drosophila)
chr1_-_151310707 0.086 NM_001017418
SPRR2B
small proline-rich protein 2B
chr12_+_21417068 0.085 NM_000415
IAPP
islet amyloid polypeptide
chr19_-_11549441 0.084 ACP5
acid phosphatase 5, tartrate resistant
chr5_+_31834787 0.082 NM_178140
PDZD2
PDZ domain containing 2
chr1_+_51206963 0.081 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr17_+_7474177 0.080 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr1_+_26973804 0.079 ARID1A
AT rich interactive domain 1A (SWI-like)
chr2_+_37282516 0.079 LOC100505876
hypothetical LOC100505876
chr8_-_74822496 0.078 NM_001164384
STAU2
staufen, RNA binding protein, homolog 2 (Drosophila)
chr1_+_66570363 0.078 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr10_+_49184658 0.077 MAPK8
mitogen-activated protein kinase 8
chr19_-_49523747 0.077 ZFP112
zinc finger protein 112 homolog (mouse)
chr15_+_89248423 0.077 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr10_+_5478521 0.076 NM_005863
NET1
neuroepithelial cell transforming 1
chr1_+_34997928 0.074 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr19_-_45141473 0.073 LOC440525
PRR13
proline rich 13 pseudogene
proline rich 13
chr17_-_46479127 0.071 SPAG9
sperm associated antigen 9
chr12_-_7739591 0.071 NM_020634
GDF3
growth differentiation factor 3
chr17_-_33043514 0.069 NM_001163544
NM_001163545
NM_001163546
NM_001163547
NM_007247
NM_080550
NM_198882
SYNRG






synergin, gamma






chr19_-_45947667 0.069 NM_198476
C19orf54
chromosome 19 open reading frame 54
chr9_-_14712669 0.067 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr11_+_117452936 0.066 NM_001083947
NM_001173551
NM_001173552
NM_019894
TMPRSS4



transmembrane protease, serine 4



chr22_-_30071761 0.066 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr7_+_141084591 0.065 NM_003143
SSBP1
single-stranded DNA binding protein 1
chr5_-_176365971 0.065 NM_016290
UIMC1
ubiquitin interaction motif containing 1
chr1_-_117011824 0.064 NM_001007237
NM_001542
IGSF3

immunoglobulin superfamily, member 3

chr4_-_149582948 0.062 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr1_+_111963920 0.061 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chr1_-_110949867 0.061 NM_004974
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr2_+_102456193 0.061 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr1_+_89796859 0.060 NM_015350
LRRC8B
leucine rich repeat containing 8 family, member B
chr17_-_59349867 0.059 NM_000515
NM_022559
NM_022560
NM_022561
NM_022562
GH1




growth hormone 1




chr17_+_7406040 0.059 NM_015670
SENP3
SUMO1/sentrin/SMT3 specific peptidase 3
chr6_-_29120930 0.059 NM_030903
OR2W1
olfactory receptor, family 2, subfamily W, member 1
chr6_-_90119068 0.058 UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr11_-_124311512 0.058 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr7_-_718609 0.058 PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr18_-_72857951 0.057 MBP
myelin basic protein
chr3_+_130014957 0.056 RAB7A
RAB7A, member RAS oncogene family
chr17_-_58877276 0.056 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr7_+_107008439 0.056 NM_001008405
BCAP29
B-cell receptor-associated protein 29
chr2_-_200030944 0.055 NM_001172509
SATB2
SATB homeobox 2
chr17_+_7732759 0.055 NM_001005273
NM_005852
CHD3

chromodomain helicase DNA binding protein 3

chr8_-_74821610 0.055 STAU2
LOC729696
staufen, RNA binding protein, homolog 2 (Drosophila)
hypothetical protein LOC729696
chr7_+_99865189 0.055 NM_019606
MEPCE
methylphosphate capping enzyme
chr16_+_29728932 0.054 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr6_-_26232109 0.054 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr17_-_59342319 0.054 NM_001318
NM_022579
NM_022580
NM_022581
CSHL1



chorionic somatomammotropin hormone-like 1



chr8_-_74821636 0.053 NM_001164380
NM_001164381
NM_001164382
NM_001164383
NM_001164385
NM_014393
STAU2





staufen, RNA binding protein, homolog 2 (Drosophila)





chr17_+_55325224 0.052 NM_003161
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr2_+_234265059 0.052 NM_205862
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr19_-_60458915 0.051 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr7_-_13992351 0.050 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr3_+_139211639 0.050 NM_016369
CLDN18
claudin 18
chr7_-_718658 0.050 NM_002735
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr15_-_41346346 0.050 NM_004245
NM_201631
TGM5

transglutaminase 5

chr1_-_40335504 0.048 PPT1
palmitoyl-protein thioesterase 1
chrX_+_100241453 0.048 NM_006733
CENPI
centromere protein I
chr22_-_49363209 0.048 NM_001145137
CPT1B
carnitine palmitoyltransferase 1B (muscle)
chr2_-_61551403 0.047 USP34
ubiquitin specific peptidase 34
chr1_-_180624380 0.046 GLUL
glutamate-ammonia ligase
chr19_-_48976852 0.046 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr13_+_108079570 0.046 NM_001198950
MYO16
myosin XVI
chr22_-_37214480 0.046 NM_001098505
NM_030881
DDX17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr7_-_149101227 0.044 NM_207336
ZNF467
zinc finger protein 467
chr1_-_23998515 0.043 NM_001127621
GALE
UDP-galactose-4-epimerase
chr2_-_68952006 0.043 NM_014482
BMP10
bone morphogenetic protein 10
chr1_+_145479805 0.043 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr3_+_25444753 0.042 NM_016152
RARB
retinoic acid receptor, beta
chr3_+_134985566 0.042 NM_021203
SRPRB
signal recognition particle receptor, B subunit
chr12_-_6995988 0.041 NM_005768
LPCAT3
lysophosphatidylcholine acyltransferase 3
chrX_-_53646332 0.040 HUWE1
HECT, UBA and WWE domain containing 1
chr1_-_152201814 0.040 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_-_40335496 0.039 PPT1
palmitoyl-protein thioesterase 1
chr12_+_94776901 0.039 SNRPF
small nuclear ribonucleoprotein polypeptide F
chrX_-_129127484 0.039 NM_145813
NM_001130847
NM_004208
NM_145812
AIFM1



apoptosis-inducing factor, mitochondrion-associated, 1



chr15_+_89212888 0.039 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr3_-_196792274 0.038 NM_001647
APOD
apolipoprotein D
chr12_+_55896844 0.038 NM_007224
NXPH4
neurexophilin 4
chr17_+_7096095 0.037 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr1_+_157441133 0.037 NM_002036
DARC
Duffy blood group, chemokine receptor
chr1_+_51206819 0.036 NM_001262
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr17_-_59304729 0.036 NM_020991
NM_022644
NM_022645
CSH2


chorionic somatomammotropin hormone 2


chr1_-_153498565 0.035 SCAMP3
secretory carrier membrane protein 3
chr5_-_39238818 0.035 FYB
FYN binding protein
chr1_+_17719405 0.034 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr5_-_132140786 0.034 NM_001098811
NM_001098812
NM_015146
SEPT8


septin 8


chr6_+_30799130 0.033 TUBB
tubulin, beta
chr15_-_38387266 0.033 PLCB2
phospholipase C, beta 2
chrX_+_16714452 0.032 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr13_-_22905822 0.031 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr17_+_3047559 0.031 NM_012352
OR1A2
olfactory receptor, family 1, subfamily A, member 2
chr18_-_72858037 0.031 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr15_-_38387317 0.031 PLCB2
phospholipase C, beta 2
chrX_+_90976314 0.030 NM_014522
NM_032968
NM_032969
PCDH11X


protocadherin 11 X-linked


chr10_-_35403173 0.030 NM_001198778
NM_001198779
CUL2

cullin 2

chr11_+_68614059 0.029


chr12_+_121180439 0.029 MLXIP
MLX interacting protein
chr9_+_113327259 0.028 NM_001007169
NM_133464
ZNF483

zinc finger protein 483

chr11_+_60746396 0.028 NM_001079808
PGA5
PGA3
PGA4
pepsinogen 5, group I (pepsinogen A)
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr7_+_86112012 0.028 GRM3
glutamate receptor, metabotropic 3
chr14_+_71469538 0.028 NM_004296
RGS6
regulator of G-protein signaling 6
chr1_-_11830328 0.028 NM_006172
NPPA
natriuretic peptide A
chr7_+_2248966 0.028 NM_198953
NM_198954
NUDT1

nudix (nucleoside diphosphate linked moiety X)-type motif 1

chr1_+_181708272 0.027 SMG7
Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr16_+_66153810 0.027 NM_001191022
NM_006565
CTCF

CCCTC-binding factor (zinc finger protein)

chr16_+_31178812 0.027 ITGAM
integrin, alpha M (complement component 3 receptor 3 subunit)
chr9_-_37024358 0.027 NM_016734
PAX5
paired box 5
chr2_-_174821486 0.027 OLA1
Obg-like ATPase 1
chr7_-_22518200 0.026 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr17_+_7402788 0.026 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.