Motif ID: ESR1.p2

Z-value: 1.185


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
ESR1 2099 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESR1chr6_+_152168500-0.175.2e-01Click!


Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_129445002 1.497 APLP2
amyloid beta (A4) precursor-like protein 2
chr11_+_129445017 1.492 APLP2
amyloid beta (A4) precursor-like protein 2
chr11_+_129444997 1.293 APLP2
amyloid beta (A4) precursor-like protein 2
chr22_-_18309447 1.271 TXNRD2
thioredoxin reductase 2
chr11_+_129444877 1.226 NM_001142276
NM_001142277
NM_001142278
NM_001642
APLP2



amyloid beta (A4) precursor-like protein 2



chr4_-_57671307 1.203 IGFBP7
insulin-like growth factor binding protein 7
chr6_+_31976754 1.132 NM_001178063
C2
complement component 2
chr6_+_148705646 1.109 SASH1
SAM and SH3 domain containing 1
chr6_+_148705421 1.082 NM_015278
SASH1
SAM and SH3 domain containing 1
chr15_-_50375143 1.065 NM_018728
MYO5C
myosin VC
chr22_-_18309333 1.027 NM_006440
TXNRD2
thioredoxin reductase 2
chr10_+_115428924 1.019 NM_033340
CASP7
caspase 7, apoptosis-related cysteine peptidase
chr7_+_45894480 0.990 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr22_-_18309250 0.978 TXNRD2
thioredoxin reductase 2
chr6_+_7486836 0.960 DSP
desmoplakin
chr16_+_54072969 0.937 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr18_+_53862744 0.936 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_+_7486891 0.924 DSP
desmoplakin
chr11_-_116213511 0.924 NM_000039
APOA1
apolipoprotein A-I
chr6_+_7486862 0.920 NM_001008844
NM_004415
DSP

desmoplakin


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
2.70 1.90e-02 GO:0019199 transmembrane receptor protein kinase activity
1.12 4.64e-02 GO:0005515 protein binding