Motif ID: TFAP2B.p2

Z-value: 1.782


Transcription factors associated with TFAP2B.p2:

Gene SymbolEntrez IDGene Name
TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFAP2Bchr6_+_50894397-0.292.8e-01Click!


Activity profile for motif TFAP2B.p2.

activity profile for motif TFAP2B.p2


Sorted Z-values histogram for motif TFAP2B.p2

Sorted Z-values for motif TFAP2B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_74432800 3.952 TIMP2
TIMP metallopeptidase inhibitor 2
chr2_-_160972606 3.923 RBMS1
RNA binding motif, single stranded interacting protein 1
chr17_-_74433048 3.222 NM_003255
 TIMP2
TIMP metallopeptidase inhibitor 2
chr3_-_151171190 2.837 NM_002628
NM_053024
 PFN2

profilin 2

chr3_-_130807865 2.787 NM_015103
 PLXND1
plexin D1
chr14_+_105012106 2.724 NM_001312
 CRIP2
cysteine-rich protein 2
chr17_-_74432671 2.708 TIMP2
TIMP metallopeptidase inhibitor 2
chr18_-_5533967 2.666 NM_012307
 EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr1_-_95165037 2.562 CNN3
calponin 3, acidic
chr11_-_65396775 2.468 NM_016938
 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr18_-_24011349 2.360 NM_001792
 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr20_-_49818268 2.331 ATP9A
ATPase, class II, type 9A
chr1_-_95165089 2.265 NM_001839
 CNN3
calponin 3, acidic
chr12_-_105165805 2.133 NM_006825
 CKAP4
cytoskeleton-associated protein 4
chr8_+_136538739 2.088 NM_006558
 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr1_+_24944554 2.059 CLIC4
chloride intracellular channel 4
chr1_-_85703321 2.054 NM_012137
 DDAH1
dimethylarginine dimethylaminohydrolase 1
chrX_+_9943793 2.050 NM_015691
 WWC3
WWC family member 3
chr14_-_29466562 1.994 NM_002742
 PRKD1
protein kinase D1
chr20_-_49818306 1.991 NM_006045
 ATP9A
ATPase, class II, type 9A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.39 1.85e-04 GO:0000904 cell morphogenesis involved in differentiation
1.38 2.09e-03 GO:0048812 neuron projection morphogenesis
1.37 9.25e-05 GO:0000902 cell morphogenesis
1.37 3.70e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.37 6.12e-03 GO:0007409 axonogenesis
1.36 1.31e-03 GO:0032990 cell part morphogenesis
1.36 1.66e-03 GO:0048858 cell projection morphogenesis
1.36 2.37e-03 GO:0031175 neuron projection development
1.35 9.38e-05 GO:0030030 cell projection organization
1.35 1.19e-04 GO:0032989 cellular component morphogenesis
1.32 1.25e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.30 2.39e-02 GO:0048666 neuron development
1.29 7.42e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.28 4.54e-04 GO:0048468 cell development
1.27 2.22e-03 GO:0048699 generation of neurons
1.26 4.30e-03 GO:0022008 neurogenesis
1.24 1.61e-05 GO:0009653 anatomical structure morphogenesis
1.19 9.67e-03 GO:0007399 nervous system development
1.18 7.39e-04 GO:0030154 cell differentiation
1.17 1.10e-03 GO:0048869 cellular developmental process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
1.78 4.16e-03 GO:0030027 lamellipodium
1.71 7.59e-07 GO:0031252 cell leading edge
1.67 7.56e-03 GO:0005925 focal adhesion
1.64 1.50e-02 GO:0005924 cell-substrate adherens junction
1.63 1.18e-02 GO:0030055 cell-substrate junction
1.62 6.17e-04 GO:0005912 adherens junction
1.56 1.95e-03 GO:0070161 anchoring junction
1.36 2.73e-02 GO:0015629 actin cytoskeleton
1.13 2.41e-02 GO:0044428 nuclear part
1.12 6.51e-09 GO:0005634 nucleus
1.09 2.18e-09 GO:0005737 cytoplasm
1.08 3.72e-16 GO:0044424 intracellular part
1.08 5.02e-11 GO:0043226 organelle
1.08 6.29e-11 GO:0043229 intracellular organelle
1.08 1.10e-08 GO:0043227 membrane-bounded organelle
1.08 1.43e-08 GO:0043231 intracellular membrane-bounded organelle
1.08 5.05e-03 GO:0044422 organelle part
1.08 6.81e-03 GO:0044446 intracellular organelle part
1.07 1.98e-16 GO:0005622 intracellular
1.07 9.70e-03 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
1.42 3.34e-03 GO:0008134 transcription factor binding
1.37 1.82e-02 GO:0003779 actin binding
1.29 1.78e-02 GO:0008092 cytoskeletal protein binding
1.10 9.99e-10 GO:0005515 protein binding
1.04 6.04e-04 GO:0005488 binding