Motif ID: GLI1..3.p2

Z-value: 0.939


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI3chr7_-_422431420.421.1e-01Click!
GLI1chr12_+_56140184-0.136.2e-01Click!
GLI2chr2_+_121271336-0.029.6e-01Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_37660568 2.399 NM_003246
THBS1
thrombospondin 1
chr3_-_31998241 1.655 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chrX_+_55951280 1.490


chr10_+_53744043 1.303 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr19_-_54835162 1.302 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr7_+_100557098 1.288 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr6_-_3697244 1.287 NM_183373
C6orf145
chromosome 6 open reading frame 145
chr1_+_43837096 1.196 PTPRF
protein tyrosine phosphatase, receptor type, F
chr17_+_15788955 1.145 NM_000676
ADORA2B
adenosine A2b receptor
chr2_+_9264360 1.141 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr3_-_31997738 1.138 OSBPL10
oxysterol binding protein-like 10
chr3_-_187025501 1.081 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr5_-_121440704 1.067 NM_001178102
LOX
lysyl oxidase
chr16_+_31390567 1.050 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr8_-_17599438 1.021 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr11_+_44074322 1.010 NM_000401
EXT2
exostosin 2
chr2_+_9264327 0.990 NM_001135191
NM_003887
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr5_+_52812165 0.985 FST
follistatin
chr21_+_17807167 0.948 NM_001338
CXADR
coxsackie virus and adenovirus receptor
chr10_-_46593923 0.945 NM_001040084
NM_001098845
ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 13 of 13 entries
enrichment   p-value GO term description
1.47 4.69e-06 GO:0009653 anatomical structure morphogenesis
1.45 2.44e-02 GO:0048468 cell development
1.39 2.09e-03 GO:0009966 regulation of signal transduction
1.39 4.46e-02 GO:0010646 regulation of cell communication
1.38 9.31e-04 GO:0023051 regulation of signaling
1.36 8.12e-03 GO:0007399 nervous system development
1.32 5.08e-07 GO:0048856 anatomical structure development
1.32 2.59e-06 GO:0048731 system development
1.31 4.33e-03 GO:0048869 cellular developmental process
1.31 6.31e-03 GO:0030154 cell differentiation
1.26 8.64e-06 GO:0032502 developmental process
1.26 8.28e-05 GO:0007275 multicellular organismal development
1.20 1.53e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.43 3.20e-03 GO:0005925 focal adhesion
2.33 7.76e-03 GO:0005924 cell-substrate adherens junction
2.23 1.76e-02 GO:0030055 cell-substrate junction
2.21 1.27e-03 GO:0005912 adherens junction
2.20 3.87e-04 GO:0070161 anchoring junction
1.77 4.06e-02 GO:0016323 basolateral plasma membrane
1.53 1.39e-02 GO:0030054 cell junction
1.30 4.42e-02 GO:0005856 cytoskeleton
1.09 2.19e-02 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.95 1.33e-02 GO:0005543 phospholipid binding
1.76 3.04e-02 GO:0005083 small GTPase regulator activity
1.44 8.28e-03 GO:0030234 enzyme regulator activity
1.11 5.56e-03 GO:0005515 protein binding