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Motif ID: ARID5B.p2

Z-value: 0.600

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_-_79899748	1.076	NM_002941	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_+_102113410	1.010
chr14_-_64479198	0.913	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chrX_-_131375217	0.889	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr17_-_61655915	0.776	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr2_-_215949566	0.760		FN1	fibronectin 1
chr11_+_101488380	0.740	NM_001195045	YAP1	Yes-associated protein 1
chr20_-_14266200	0.621	NM_013281 NM_198391	FLRT3	fibronectin leucine rich transmembrane protein 3
chr3_-_131081910	0.582	NM_001017395	TMCC1	transmembrane and coiled-coil domain family 1
chr9_-_122852356	0.539	NM_001735	C5	complement component 5
chr3_-_188946168	0.524	NM_001706	BCL6	B-cell CLL/lymphoma 6
chr15_+_49988882	0.497		TMOD3	tropomodulin 3 (ubiquitous)
chr4_+_155707089	0.465		FGB	fibrinogen beta chain
chr1_-_151280201	0.459	NM_006945	SPRR2D	small proline-rich protein 2D
chr1_-_151352587	0.458	NM_001014450	SPRR2A SPRR2F	small proline-rich protein 2A small proline-rich protein 2F
chr6_+_30238961	0.453	NM_033229	TRIM15	tripartite motif containing 15
chr14_-_93914634	0.447		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_151310707	0.438	NM_001017418	SPRR2B	small proline-rich protein 2B
chrM_+_12283	0.421
chr5_-_125956996	0.419		ALDH7A1	aldehyde dehydrogenase 7 family, member A1
chr6_+_167624792	0.405	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr4_+_89115862	0.397		SPP1	secreted phosphoprotein 1
chr12_-_28016182	0.393	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr16_+_80626456	0.393		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chrX_-_105169370	0.378	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr18_+_59705918	0.377	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr18_+_53865455	0.372	NM_001144964	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr10_-_29963906	0.370	NM_021738	SVIL	supervillin
chr4_+_89115825	0.346	NM_000582 NM_001040058 NM_001040060	SPP1	secreted phosphoprotein 1
chr4_+_74488910	0.326		ALB	albumin
chr16_+_80626459	0.322		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr2_+_68815416	0.319	NM_001007231 NM_001166277	ARHGAP25	Rho GTPase activating protein 25
chr2_-_88208650	0.310	NM_001443	FABP1	fatty acid binding protein 1, liver
chr10_+_124135574	0.308	NM_001195608	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr7_+_133862883	0.303	NM_020299	AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)
chr16_+_80626402	0.301		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_29378694	0.297	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr4_-_69852090	0.294	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr15_+_22619886	0.286	NM_022806 NM_022807 NM_022808	SNRPN	small nuclear ribonucleoprotein polypeptide N
chr12_+_54611212	0.285	NM_001345	DGKA	diacylglycerol kinase, alpha 80kDa
chr17_-_23721351	0.282		VTN	vitronectin
chr17_-_23721420	0.279		VTN	vitronectin
chr16_+_30118036	0.278	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr8_-_17787342	0.274		FGL1	fibrinogen-like 1
chr10_-_105835525	0.272		COL17A1	collagen, type XVII, alpha 1
chr9_+_124836666	0.263	NM_005294	GPR21	G protein-coupled receptor 21
chr6_-_47361921	0.262		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr11_+_129484540	0.257		APLP2	amyloid beta (A4) precursor-like protein 2
chr3_-_198784590	0.248	NM_203315	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr2_+_101874765	0.241		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr6_-_47362102	0.239		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr1_-_60164912	0.233	NM_000775	CYP2J2	cytochrome P450, family 2, subfamily J, polypeptide 2
chr7_+_94377145	0.228	NM_001166161 NM_001166162 NM_001166163	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr1_-_151333624	0.222	NM_001024209	SPRR2E	small proline-rich protein 2E
chr2_-_242205556	0.215	NM_001164356	THAP4	THAP domain containing 4
chr17_-_36347197	0.211	NM_015515	KRT23	keratin 23 (histone deacetylase inducible)
chr6_-_2785682	0.211		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr19_-_47723183	0.207		CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr1_+_116727514	0.203	NM_001160234	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr18_+_18767275	0.201	NM_002894	RBBP8	retinoblastoma binding protein 8
chr12_-_49689295	0.199	NM_001174130	SLC11A2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr10_-_105835609	0.197	NM_000494	COL17A1	collagen, type XVII, alpha 1
chr5_-_43326922	0.197		HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr4_+_74500748	0.192		ALB	albumin
chrX_-_33267646	0.190	NM_000109	DMD	dystrophin
chr2_-_165133239	0.188		GRB14	growth factor receptor-bound protein 14
chr18_+_59405513	0.188	NM_012397	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr9_-_116920232	0.182	NM_002160	TNC	tenascin C
chr9_+_33740463	0.179	NM_001197097 NM_007343 NM_001197098	PRSS3	protease, serine, 3
chr17_-_7023378	0.179	NM_001197216 NM_001671	ASGR1	asialoglycoprotein receptor 1
chr4_-_155731288	0.173	NM_000508 NM_021871	FGA	fibrinogen alpha chain
chr18_-_28247186	0.172
chr4_-_90197140	0.170	NM_014883	FAM13A	family with sequence similarity 13, member A
chr4_+_74491272	0.167		ALB	albumin
chr2_+_211166323	0.164	NM_001122634	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr9_-_115877104	0.161		AMBP	alpha-1-microglobulin/bikunin precursor
chr18_+_27281729	0.160	NM_001944	DSG3	desmoglein 3
chr12_+_68028397	0.160	NM_000239	LYZ	lysozyme
chr19_+_48772791	0.159	NM_001193621	LOC390940	hypothetical protein LOC390940
chr12_-_8706533	0.156		MFAP5	microfibrillar associated protein 5
chr3_+_12367993	0.156	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr4_+_89115892	0.152		SPP1	secreted phosphoprotein 1
chr10_+_126140330	0.152	NM_001167880 NM_022126	LHPP	phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr21_+_38550533	0.151	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15
chr20_+_19863716	0.149		RIN2	Ras and Rab interactor 2
chr19_+_61151009	0.149	NM_176811	NLRP8	NLR family, pyrin domain containing 8
chr11_+_43622348	0.147
chr1_-_245120900	0.146		AHCTF1	AT hook containing transcription factor 1
chr5_+_176449156	0.144	NM_022963	FGFR4	fibroblast growth factor receptor 4
chr1_-_195818927	0.143		DENND1B	DENN/MADD domain containing 1B
chr4_+_75449720	0.134	NM_001432	EREG	epiregulin
chr22_+_38903825	0.134	NM_001162501 NM_015088	TNRC6B	trinucleotide repeat containing 6B
chr6_-_32247134	0.130		AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr4_+_187424111	0.129	NM_000128	F11	coagulation factor XI
chr7_-_87180499	0.126	NM_000927	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr1_+_13784553	0.126	NM_001006624 NM_001006625	PDPN	podoplanin
chr18_-_59480082	0.125	NM_006919	SERPINB3 SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 3 serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr2_+_128644510	0.124		UGGT1	UDP-glucose glycoprotein glucosyltransferase 1
chr22_+_19458378	0.121	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr2_+_101874809	0.119		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_7023283	0.118		ASGR1	asialoglycoprotein receptor 1
chr1_+_20837001	0.118
chr18_-_59462469	0.118	NM_002974	SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr19_-_56223095	0.117	NM_001167605 NM_006853	KLK11	kallikrein-related peptidase 11
chr17_+_54587882	0.117		PRR11	proline rich 11
chr6_-_64087806	0.116	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr11_+_57123927	0.116		SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr17_-_53847937	0.115		RNF43	ring finger protein 43
chr2_+_113591940	0.115	NM_000577 NM_173841 NM_173843	IL1RN	interleukin 1 receptor antagonist
chr1_-_58920315	0.115
chr7_+_75892187	0.113	NM_001110354	ZP3	zona pellucida glycoprotein 3 (sperm receptor)
chr17_+_58440629	0.111	NM_025185	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr14_-_30927931	0.111	NM_015473	HEATR5A	HEAT repeat containing 5A
chr6_+_64344307	0.111		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr6_+_131508153	0.109	NM_016377	AKAP7	A kinase (PRKA) anchor protein 7
chr8_+_104900591	0.107	NM_014677	RIMS2	regulating synaptic membrane exocytosis 2
chr1_+_92405196	0.106	NM_015237	KIAA1107	KIAA1107
chr18_-_44723116	0.106	NM_001190823	SMAD7	SMAD family member 7
chr10_-_118670968	0.103		KIAA1598	KIAA1598
chr7_+_29486010	0.103	NM_001039936	CHN2	chimerin (chimaerin) 2
chr1_+_24713396	0.103		RCAN3	RCAN family member 3
chrX_-_10495476	0.101	NM_001193278 NM_001193279 NM_001193280 NM_001193281	MID1	midline 1 (Opitz/BBB syndrome)
chr6_-_32920689	0.101	NM_004159	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr6_+_31731667	0.101		APOM	apolipoprotein M
chr8_-_17599438	0.101	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr19_-_38052481	0.101	NM_001126335 NM_014270	SLC7A9	solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chrM_+_13453	0.097
chr12_-_84754289	0.097	NM_005447	RASSF9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chrX_-_110541029	0.097	NM_000555	DCX	doublecortin
chr7_+_23252945	0.096		GPNMB	glycoprotein (transmembrane) nmb
chr3_-_180452338	0.094	NM_171830	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr16_-_70763849	0.093	NM_001160213	PMFBP1	polyamine modulated factor 1 binding protein 1
chr12_-_10853940	0.088	NM_023917	TAS2R9	taste receptor, type 2, member 9
chr10_-_116276651	0.088	NM_006720	ABLIM1	actin binding LIM protein 1
chr13_+_52114565	0.085		HNRNPA1L2	heterogeneous nuclear ribonucleoprotein A1-like 2
chr14_-_20642629	0.085	NM_001102454	ZNF219	zinc finger protein 219
chrY_-_2715478	0.084	NM_003140	SRY	sex determining region Y
chr13_-_47885248	0.084		LPAR6	lysophosphatidic acid receptor 6
chr10_+_32896656	0.084	NM_024688	C10orf68	chromosome 10 open reading frame 68
chr3_+_142175329	0.084		SLC25A36	solute carrier family 25, member 36
chr21_+_34112456	0.082		ITSN1	intersectin 1 (SH3 domain protein)
chr2_+_223433919	0.082	NM_004457 NM_203372	ACSL3	acyl-CoA synthetase long-chain family member 3
chr6_+_31731647	0.082	NM_019101	APOM	apolipoprotein M
chr7_+_23252802	0.081	NM_001005340 NM_002510	GPNMB	glycoprotein (transmembrane) nmb
chr1_-_151296611	0.081	NM_005988	SPRR2A	small proline-rich protein 2A
chr12_-_23995109	0.080		SOX5	SRY (sex determining region Y)-box 5
chr9_+_124835608	0.079		RABGAP1 GPR21	RAB GTPase activating protein 1 G protein-coupled receptor 21
chr15_+_57696200	0.077		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr6_-_136829705	0.077	NM_001198615	MAP7	microtubule-associated protein 7
chr7_+_23252909	0.076		GPNMB	glycoprotein (transmembrane) nmb
chr10_-_11614279	0.075	NM_001080491	USP6NL	USP6 N-terminal like
chr6_+_29187565	0.072	NM_001005216	OR2J3	olfactory receptor, family 2, subfamily J, member 3
chrM_-_15569	0.070
chr7_-_24764082	0.069	NM_001127454 NM_004403	DFNA5	deafness, autosomal dominant 5
chr15_-_63199228	0.069		PDCD7	programmed cell death 7
chr17_-_8364942	0.068		MYH10	myosin, heavy chain 10, non-muscle
chr12_+_117067214	0.068		PEBP1	phosphatidylethanolamine binding protein 1
chr12_-_8706637	0.067	NM_003480	MFAP5	microfibrillar associated protein 5
chr2_-_74472486	0.067		DCTN1	dynactin 1
chr2_-_222867171	0.066		PAX3	paired box 3
chr19_-_60458915	0.066		PPP6R1	protein phosphatase 6, regulatory subunit 1
chr7_-_22518200	0.065		EEF1A1	eukaryotic translation elongation factor 1 alpha 1
chr1_-_158759606	0.065	NM_001184714 NM_001184715 NM_001184716 NM_052931	SLAMF6	SLAM family member 6
chr12_-_23628774	0.064	NM_178010	SOX5	SRY (sex determining region Y)-box 5
chr5_+_92944680	0.063	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chr20_-_33783409	0.063		RBM39	RNA binding motif protein 39
chr2_-_74472480	0.063		DCTN1	dynactin 1
chrM_+_4465	0.061
chr13_-_47885018	0.060		LPAR6	lysophosphatidic acid receptor 6
chr16_-_28528780	0.060	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr1_+_170894780	0.060	NM_000639	FASLG	Fas ligand (TNF superfamily, member 6)
chr1_+_169747788	0.060		PRRC2C	proline-rich coiled-coil 2C
chr6_-_11490487	0.060	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chrX_-_106248674	0.059		RBM41	RNA binding motif protein 41
chr2_-_74472428	0.056		DCTN1	dynactin 1
chr14_-_106282128	0.055		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_48902692	0.055	NM_001113547	LIMA1	LIM domain and actin binding 1
chr3_+_44891101	0.054	NM_003241	TGM4	transglutaminase 4 (prostate)
chr3_+_100840129	0.053	NM_001850 NM_020351	COL8A1	collagen, type VIII, alpha 1
chr9_-_103187082	0.053	NM_001701	BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr7_+_141110365	0.051	NM_016943	TAS2R3	taste receptor, type 2, member 3
chr7_+_65057942	0.050		VKORC1L1	vitamin K epoxide reductase complex, subunit 1-like 1
chr1_-_13263334	0.050	NM_001012276	PRAMEF8 PRAMEF7	PRAME family member 8 PRAME family member 7
chr22_-_41372920	0.049	NM_001129819 NM_001171661 NM_007326	CYB5R3	cytochrome b5 reductase 3
chr15_-_50270856	0.049	NM_016194	GNB5	guanine nucleotide binding protein (G protein), beta 5
chr20_+_1041905	0.049	NM_178578	PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr5_+_36644187	0.049	NM_001166695	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_63750611	0.049	NM_182913	SYNE2	spectrin repeat containing, nuclear envelope 2
chr11_-_73559507	0.049	NM_015531	C2CD3	C2 calcium-dependent domain containing 3
chr15_+_22652790	0.047	NM_022805	SNRPN	small nuclear ribonucleoprotein polypeptide N
chr8_+_92184022	0.046	NM_001129890	LRRC69	leucine rich repeat containing 69
chr15_+_69220841	0.046	NM_024817	THSD4	thrombospondin, type I, domain containing 4
chr8_+_67096344	0.046	NM_033105	DNAJC5B	DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr1_-_115039614	0.045	NM_000036 NM_001172626	AMPD1	adenosine monophosphate deaminase 1
chr8_+_22909305	0.045	NM_001160037	RHOBTB2	Rho-related BTB domain containing 2
chr1_+_234748187	0.045	NM_201545	LGALS8	lectin, galactoside-binding, soluble, 8
chr16_-_70763524	0.045	NM_031293	PMFBP1	polyamine modulated factor 1 binding protein 1
chr9_+_116943917	0.044	NM_017418	DEC1	deleted in esophageal cancer 1
chr20_+_34163671	0.044	NM_177996	EPB41L1	erythrocyte membrane protein band 4.1-like 1
chr11_-_73856241	0.043	NM_005472	KCNE3	potassium voltage-gated channel, Isk-related family, member 3

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.40	1.36e-04	GO:0032501	multicellular organismal process
1.32	6.93e-04	GO:0050896	response to stimulus
6.61	8.27e-04	GO:0010951	negative regulation of endopeptidase activity
3.79	1.57e-03	GO:0052548	regulation of endopeptidase activity
3.63	2.94e-03	GO:0052547	regulation of peptidase activity
2.44	3.24e-03	GO:0051336	regulation of hydrolase activity
4.75	9.87e-03	GO:0010466	negative regulation of peptidase activity
3.05	2.03e-02	GO:0008202	steroid metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
2.23	1.33e-06	GO:0044421	extracellular region part
1.83	8.37e-06	GO:0005576	extracellular region
2.26	3.70e-05	GO:0005615	extracellular space
1.41	1.12e-03	GO:0071944	cell periphery
1.41	1.50e-03	GO:0005886	plasma membrane
1.53	5.06e-03	GO:0044459	plasma membrane part
19.22	5.69e-03	GO:0005577	fibrinogen complex
5.31	8.95e-03	GO:0031091	platelet alpha granule
5.73	1.39e-02	GO:0031093	platelet alpha granule lumen
2.49	1.51e-02	GO:0031012	extracellular matrix
5.61	1.63e-02	GO:0034774	secretory granule lumen
5.38	2.20e-02	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
9.89	2.33e-02	GO:0001533	cornified envelope
5.18	2.94e-02	GO:0031983	vesicle lumen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
6.41	7.44e-05	GO:0004867	serine-type endopeptidase inhibitor activity
4.13	1.89e-03	GO:0004866	endopeptidase inhibitor activity
4.06	2.32e-03	GO:0030414	peptidase inhibitor activity
3.96	3.12e-03	GO:0061135	endopeptidase regulator activity
4.08	1.00e-02	GO:0008201	heparin binding
3.27	2.69e-02	GO:0061134	peptidase regulator activity
3.39	3.33e-02	GO:0005539	glycosaminoglycan binding