Motif ID: ARID5B.p2

Z-value: 0.600


Transcription factors associated with ARID5B.p2:

Gene SymbolEntrez IDGene Name
ARID5B 84159 AT rich interactive domain 5B (MRF1-like)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ARID5Bchr10_+_633310180.039.2e-01Click!


Activity profile for motif ARID5B.p2.

activity profile for motif ARID5B.p2


Sorted Z-values histogram for motif ARID5B.p2

Sorted Z-values for motif ARID5B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARID5B.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_79899748 1.076 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_+_102113410 1.010


chr14_-_64479198 0.913 NM_002083
 GPX2
glutathione peroxidase 2 (gastrointestinal)
chrX_-_131375217 0.889 NM_001170701
NM_001170702
NM_001170703
 MBNL3


muscleblind-like 3 (Drosophila)


chr17_-_61655915 0.776 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chr2_-_215949566 0.760 FN1
fibronectin 1
chr11_+_101488380 0.740 NM_001195045
 YAP1
Yes-associated protein 1
chr20_-_14266200 0.621 NM_013281
NM_198391
 FLRT3

fibronectin leucine rich transmembrane protein 3

chr3_-_131081910 0.582 NM_001017395
 TMCC1
transmembrane and coiled-coil domain family 1
chr9_-_122852356 0.539 NM_001735
 C5
complement component 5
chr3_-_188946168 0.524 NM_001706
 BCL6
B-cell CLL/lymphoma 6
chr15_+_49988882 0.497 TMOD3
tropomodulin 3 (ubiquitous)
chr4_+_155707089 0.465 FGB
fibrinogen beta chain
chr1_-_151280201 0.459 NM_006945
 SPRR2D
small proline-rich protein 2D
chr1_-_151352587 0.458 NM_001014450
 SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr6_+_30238961 0.453 NM_033229
 TRIM15
tripartite motif containing 15
chr14_-_93914634 0.447 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr1_-_151310707 0.438 NM_001017418
 SPRR2B
small proline-rich protein 2B
chrM_+_12283 0.421


chr5_-_125956996 0.419 ALDH7A1
aldehyde dehydrogenase 7 family, member A1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
6.61 8.27e-04 GO:0010951 negative regulation of endopeptidase activity
4.75 9.87e-03 GO:0010466 negative regulation of peptidase activity
3.79 1.57e-03 GO:0052548 regulation of endopeptidase activity
3.63 2.94e-03 GO:0052547 regulation of peptidase activity
3.05 2.03e-02 GO:0008202 steroid metabolic process
2.44 3.24e-03 GO:0051336 regulation of hydrolase activity
1.40 1.36e-04 GO:0032501 multicellular organismal process
1.32 6.93e-04 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
19.22 5.69e-03 GO:0005577 fibrinogen complex
9.89 2.33e-02 GO:0001533 cornified envelope
5.73 1.39e-02 GO:0031093 platelet alpha granule lumen
5.61 1.63e-02 GO:0034774 secretory granule lumen
5.38 2.20e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
5.31 8.95e-03 GO:0031091 platelet alpha granule
5.18 2.94e-02 GO:0031983 vesicle lumen
2.49 1.51e-02 GO:0031012 extracellular matrix
2.26 3.70e-05 GO:0005615 extracellular space
2.23 1.33e-06 GO:0044421 extracellular region part
1.83 8.37e-06 GO:0005576 extracellular region
1.53 5.06e-03 GO:0044459 plasma membrane part
1.41 1.12e-03 GO:0071944 cell periphery
1.41 1.50e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
6.41 7.44e-05 GO:0004867 serine-type endopeptidase inhibitor activity
4.13 1.89e-03 GO:0004866 endopeptidase inhibitor activity
4.08 1.00e-02 GO:0008201 heparin binding
4.06 2.32e-03 GO:0030414 peptidase inhibitor activity
3.96 3.12e-03 GO:0061135 endopeptidase regulator activity
3.39 3.33e-02 GO:0005539 glycosaminoglycan binding
3.27 2.69e-02 GO:0061134 peptidase regulator activity