Motif ID: JUN.p2

Z-value: 1.258


Transcription factors associated with JUN.p2:

Gene SymbolEntrez IDGene Name
JUN 3725 jun oncogene
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
JUNchr1_-_590222750.693.0e-03Click!
JUNBchr19_+_12763295-0.146.0e-01Click!
JUNDchr19_-_18253413-0.048.9e-01Click!


Activity profile for motif JUN.p2.

activity profile for motif JUN.p2


Sorted Z-values histogram for motif JUN.p2

Sorted Z-values for motif JUN.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of JUN.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_12652427 3.686 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr20_+_19863716 3.080 RIN2
Ras and Rab interactor 2
chr6_+_139497933 3.056 NM_016217
HECA
headcase homolog (Drosophila)
chr19_+_16048266 2.971 TPM4
tropomyosin 4
chr19_+_16048315 2.852 TPM4
tropomyosin 4
chr19_+_16048306 2.660 TPM4
tropomyosin 4
chr2_-_216009015 2.562 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr21_+_46369606 2.519 COL6A2
collagen, type VI, alpha 2
chr3_+_8518508 2.233 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr11_+_116575249 2.066 NM_001001522
NM_003186
TAGLN

transgelin

chr3_-_101077605 2.046 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr2_-_237987509 2.013 COL6A3
collagen, type VI, alpha 3
chr2_-_237987579 1.984 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr9_-_98421894 1.963 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr4_-_186693574 1.788 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr3_+_8518539 1.748 LMCD1
LIM and cysteine-rich domains 1
chr4_-_111777651 1.695 PITX2
paired-like homeodomain 2
chr13_-_109600709 1.685 COL4A1
collagen, type IV, alpha 1
chr4_-_111777584 1.673 PITX2
paired-like homeodomain 2
chr5_-_172130766 1.638 NM_004417
DUSP1
dual specificity phosphatase 1
chr2_-_237987554 1.549 COL6A3
collagen, type VI, alpha 3
chr2_-_56003859 1.524 NM_004105
EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr21_-_43671355 1.505 NM_173354
SIK1
salt-inducible kinase 1
chr1_+_99502655 1.502 LPPR4
lipid phosphate phosphatase-related protein type 4
chr8_-_18710575 1.459 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr21_+_46370220 1.453 COL6A2
collagen, type VI, alpha 2
chr11_-_111287657 1.444 NM_001885
CRYAB
crystallin, alpha B
chr21_+_46369617 1.443 COL6A2
collagen, type VI, alpha 2
chr6_+_39868126 1.438 DAAM2
dishevelled associated activator of morphogenesis 2
chr3_+_160473729 1.436 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr1_-_20685314 1.435 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr1_-_1283770 1.394 NM_032348
MXRA8
matrix-remodelling associated 8
chr1_-_59022275 1.379 NM_002228
JUN
jun proto-oncogene
chr8_-_98359248 1.352 TSPYL5
TSPY-like 5
chr8_-_98359347 1.347 NM_033512
TSPYL5
TSPY-like 5
chr8_-_42184194 1.308 PLAT
plasminogen activator, tissue
chr8_-_42184350 1.306 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr2_+_219991342 1.298 NM_001927
DES
desmin
chr11_-_35503720 1.285 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr2_-_210876560 1.285 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr8_+_79591074 1.256 PKIA
protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr11_+_69165119 1.255 CCND1
cyclin D1
chr11_+_69165018 1.242 NM_053056
CCND1
cyclin D1
chr21_+_46370831 1.237 COL6A2
collagen, type VI, alpha 2
chr8_+_94998258 1.217 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr1_-_56750235 1.167 PPAP2B
phosphatidic acid phosphatase type 2B
chr19_+_16048047 1.155 NM_003290
TPM4
tropomyosin 4
chr3_+_189354167 1.137 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr4_-_111763655 1.135 NM_000325
PITX2
paired-like homeodomain 2
chr7_-_129379947 1.124 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr14_+_103165244 1.119 NM_001130107
NM_005552
NM_182923
KLC1


kinesin light chain 1


chr1_-_191422346 1.114 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_+_232165818 1.112 NM_152614
C2orf57
chromosome 2 open reading frame 57
chr19_+_50041400 1.110 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr3_+_62279707 1.109 C3orf14
chromosome 3 open reading frame 14
chr5_+_71438796 1.084 NM_005909
MAP1B
microtubule-associated protein 1B
chr4_+_658250 1.076 MYL5
myosin, light chain 5, regulatory
chr4_+_658312 1.060 MYL5
myosin, light chain 5, regulatory
chr2_+_30307900 1.059 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr2_+_5750229 1.054 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr5_+_34723420 1.050 NM_001145523
RAI14
retinoic acid induced 14
chr10_+_31648103 1.045 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr16_-_78192111 1.043 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chrX_-_101658297 1.035 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr2_+_33025872 1.034 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr1_+_99502435 1.015 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr16_+_85101605 1.013 NM_001451
FOXF1
forkhead box F1
chr6_-_169395847 1.008 THBS2
thrombospondin 2
chr17_-_13445942 0.997 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr14_+_87921740 0.989 NM_001040428
NM_018418
SPATA7

spermatogenesis associated 7

chr2_-_216008689 0.982 FN1
fibronectin 1
chr12_+_10256682 0.977 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr16_+_31027255 0.971 BCKDK
branched chain ketoacid dehydrogenase kinase
chr19_-_56919032 0.971 NM_001523
HAS1
hyaluronan synthase 1
chr9_+_111927601 0.968 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr7_+_134114957 0.966 CALD1
caldesmon 1
chr19_+_50041387 0.959 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr12_+_52665196 0.958 NM_017409
HOXC10
homeobox C10
chr11_-_118693021 0.954 NM_006500
MCAM
melanoma cell adhesion molecule
chr1_-_110735158 0.950 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr6_-_128883125 0.941 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr10_-_62373828 0.922 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr1_+_78243181 0.915 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr14_+_100362236 0.901 MEG3
maternally expressed 3 (non-protein coding)
chr14_+_87921818 0.899 SPATA7
spermatogenesis associated 7
chr15_-_32875040 0.898 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr17_+_38831874 0.885 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr11_-_63138483 0.883 NM_007069
PLA2G16
phospholipase A2, group XVI
chr16_+_31027231 0.882 BCKDK
branched chain ketoacid dehydrogenase kinase
chr2_+_241023703 0.879 NM_002081
GPC1
glypican 1
chr9_+_96528814 0.878 C9orf3
chromosome 9 open reading frame 3
chr9_+_96528764 0.877 NM_001193331
NM_032823
C9orf3

chromosome 9 open reading frame 3

chr11_-_63138416 0.877 PLA2G16
phospholipase A2, group XVI
chr1_+_158441770 0.875 PEA15
phosphoprotein enriched in astrocytes 15
chr9_-_14076901 0.871 NFIB
nuclear factor I/B
chr11_-_27679617 0.867 NM_170733
BDNF
brain-derived neurotrophic factor
chr12_+_12935619 0.864 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr14_+_100362204 0.854 MEG3
maternally expressed 3 (non-protein coding)
chr1_+_158441738 0.853 NM_003768
PEA15
phosphoprotein enriched in astrocytes 15
chr1_-_199742864 0.852 CSRP1
cysteine and glycine-rich protein 1
chr8_-_119192985 0.852 NM_000127
EXT1
exostosin 1
chr3_+_11242666 0.836 NM_001098211
HRH1
histamine receptor H1
chr9_+_34980266 0.835 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr16_-_10581944 0.829 NM_001424
EMP2
epithelial membrane protein 2
chr1_-_199742871 0.826 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chr3_+_9950474 0.821 CRELD1
cysteine-rich with EGF-like domains 1
chr18_+_8707368 0.805 NM_015210
KIAA0802
KIAA0802
chr1_-_199742589 0.801 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr3_+_156280129 0.800 NM_000902
MME
membrane metallo-endopeptidase
chr1_-_199742841 0.798 CSRP1
cysteine and glycine-rich protein 1
chr3_-_109423858 0.797 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chrX_-_10605726 0.789 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr22_+_36927884 0.788 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr11_-_63138516 0.783 NM_001128203
PLA2G16
phospholipase A2, group XVI
chr11_+_69165159 0.775 CCND1
cyclin D1
chr6_-_46401363 0.760 NM_005822
RCAN2
regulator of calcineurin 2
chr17_+_64020120 0.760 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr17_-_61253122 0.755 NM_001037325
CCDC46
coiled-coil domain containing 46
chr1_+_24944493 0.754 CLIC4
chloride intracellular channel 4
chr10_+_102782156 0.745 SFXN3
sideroflexin 3
chr3_-_126257425 0.743 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr5_-_131590833 0.741 NM_001017973
NM_004199
P4HA2

prolyl 4-hydroxylase, alpha polypeptide II

chr5_+_71538456 0.740 MAP1B
microtubule-associated protein 1B
chrX_-_13866451 0.738 GPM6B
glycoprotein M6B
chr17_+_64020159 0.737 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr9_-_128924819 0.737 NM_012098
ANGPTL2
angiopoietin-like 2
chr9_-_128924706 0.732 ANGPTL2
angiopoietin-like 2
chr19_+_50041424 0.728 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr10_+_102782151 0.728 SFXN3
sideroflexin 3
chr2_+_28469199 0.722 FOSL2
FOS-like antigen 2
chr3_-_188946168 0.719 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr12_-_100979923 0.716 NM_016053
CCDC53
coiled-coil domain containing 53
chr22_+_36928011 0.714 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr2_-_86704446 0.714 RNF103
ring finger protein 103
chrX_+_153325684 0.708 FAM50A
family with sequence similarity 50, member A
chr4_-_171161486 0.693 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr12_+_12935759 0.683 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr1_+_24944346 0.679 NM_013943
CLIC4
chloride intracellular channel 4
chr13_-_51878629 0.675 NM_018676
NM_199263
THSD1

thrombospondin, type I, domain containing 1

chrX_+_48317772 0.665 NM_006743
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr1_+_7753913 0.664 NM_004781
VAMP3
vesicle-associated membrane protein 3 (cellubrevin)
chr7_+_65307816 0.663 TPST1
tyrosylprotein sulfotransferase 1
chr7_+_65307691 0.662 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr9_+_96561750 0.660 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr6_-_112682573 0.655 LAMA4
laminin, alpha 4
chr8_-_18585721 0.654 PSD3
pleckstrin and Sec7 domain containing 3
chr7_+_142790047 0.651 ZYX
zyxin
chr9_+_111582317 0.651 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr17_+_22645232 0.646 NM_015626
NM_134265
WSB1

WD repeat and SOCS box containing 1

chr20_+_19818209 0.642 NM_018993
RIN2
Ras and Rab interactor 2
chr10_+_123913094 0.640 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr3_+_9950513 0.638 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr14_+_95792299 0.636 NM_000710
BDKRB1
bradykinin receptor B1
chr6_+_148705421 0.627 NM_015278
SASH1
SAM and SH3 domain containing 1
chr7_-_37922902 0.620 SFRP4
secreted frizzled-related protein 4
chr12_+_120635021 0.620 NM_001080825
TMEM120B
transmembrane protein 120B
chr6_+_148705646 0.617 SASH1
SAM and SH3 domain containing 1
chr4_-_156517394 0.615 MAP9
microtubule-associated protein 9
chrX_+_153325643 0.610 NM_004699
FAM50A
family with sequence similarity 50, member A
chr1_+_24944554 0.610 CLIC4
chloride intracellular channel 4
chr6_+_148705817 0.605 SASH1
SAM and SH3 domain containing 1
chr21_-_43903755 0.605 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr12_-_100979893 0.600 CCDC53
coiled-coil domain containing 53
chr21_+_46369911 0.600 COL6A2
collagen, type VI, alpha 2
chr7_+_142788579 0.599 ZYX
zyxin
chr6_-_116681863 0.598 NM_021648
TSPYL4
TSPY-like 4
chr19_-_63758270 0.595 CHMP2A
chromatin modifying protein 2A
chr3_+_101694244 0.586 TMEM45A
transmembrane protein 45A
chr12_-_100979869 0.585 CCDC53
coiled-coil domain containing 53
chr17_+_64020155 0.585 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr7_-_45095017 0.585 NM_001146334
NACAD
NAC alpha domain containing
chr7_+_142788521 0.583 ZYX
zyxin
chr19_-_63758184 0.582 CHMP2A
chromatin modifying protein 2A
chrX_+_12903145 0.581 NM_021109
NM_183049
TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr1_-_95165089 0.580 NM_001839
CNN3
calponin 3, acidic
chr11_+_129445002 0.579 APLP2
amyloid beta (A4) precursor-like protein 2
chr7_-_37923040 0.575 NM_003014
SFRP4
secreted frizzled-related protein 4
chr10_+_123912930 0.574 TACC2
transforming, acidic coiled-coil containing protein 2
chr7_+_142788730 0.567 ZYX
zyxin
chr22_-_37062114 0.565 CSNK1E
casein kinase 1, epsilon
chr19_-_63758289 0.563 NM_014453
CHMP2A
chromatin modifying protein 2A
chr12_-_121946635 0.556 NM_024667
VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr13_+_47705493 0.552 ITM2B
integral membrane protein 2B
chr7_+_142788480 0.551 NM_001010972
NM_003461
ZYX

zyxin

chr7_+_142788566 0.551 ZYX
zyxin
chr7_+_142788517 0.547 ZYX
zyxin
chr12_+_55201854 0.546 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr7_+_142788569 0.545 ZYX
zyxin
chr19_-_40938251 0.544 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr4_-_156517423 0.541 MAP9
microtubule-associated protein 9
chrX_-_13866565 0.540 NM_001001994
GPM6B
glycoprotein M6B
chr20_+_42644633 0.539 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr11_+_129445017 0.537 APLP2
amyloid beta (A4) precursor-like protein 2
chr4_+_146622154 0.536 NM_005900
SMAD1
SMAD family member 1
chr19_-_63758165 0.534 NM_198426
CHMP2A
chromatin modifying protein 2A
chrX_-_92815222 0.532 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr21_+_34112456 0.531 ITSN1
intersectin 1 (SH3 domain protein)
chr2_-_224175339 0.530 SCG2
secretogranin II
chr21_-_38210531 0.526 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr1_+_156229686 0.525 NM_018240
KIRREL
kin of IRRE like (Drosophila)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.08 3.10e-03 GO:0030017 sarcomere
1.45 5.14e-03 GO:0005856 cytoskeleton
2.04 7.08e-03 GO:0015629 actin cytoskeleton
2.76 1.01e-02 GO:0044449 contractile fiber part
2.63 1.32e-02 GO:0043292 contractile fiber
2.68 1.58e-02 GO:0030016 myofibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.00 1.35e-02 GO:0003779 actin binding
1.13 4.73e-02 GO:0005515 protein binding