• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: NR5A1,2.p2

Z-value: 2.338

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr11_-_5227611	4.823	NM_000559	HBG1 HBG2	hemoglobin, gamma A hemoglobin, gamma G
chr11_-_5232480	4.176	NM_000184	HBG1 HBG2	hemoglobin, gamma A hemoglobin, gamma G
chr12_-_9123126	3.125		A2M	alpha-2-macroglobulin
chr20_+_48241334	2.874		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr1_-_180621272	2.333		GLUL	glutamate-ammonia ligase
chr5_-_42847716	1.688	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chrX_+_152608159	1.683	NM_001142806	SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr14_-_103058865	1.682	NM_001823	CKB	creatine kinase, brain
chr3_-_124822113	1.641	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr14_-_103058568	1.640		CKB	creatine kinase, brain
chr3_-_124821868	1.631		MYLK	myosin light chain kinase
chr6_-_2785682	1.620		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr1_+_148125090	1.545	NM_003517	HIST2H2AC	histone cluster 2, H2ac
chr12_-_9159707	1.539		A2M	alpha-2-macroglobulin
chr12_-_9159780	1.522		A2M	alpha-2-macroglobulin
chr6_+_26381122	1.517	NM_003525	HIST1H2BI	histone cluster 1, H2bi
chr12_-_9159789	1.484	NM_000014	A2M	alpha-2-macroglobulin
chr3_+_123526700	1.426	NM_005213	CSTA	cystatin A (stefin A)
chr10_+_80777248	1.395		PPIF	peptidylprolyl isomerase F
chr10_+_80777265	1.385		PPIF	peptidylprolyl isomerase F
chr17_-_36996611	1.331	NM_000526	KRT14	keratin 14
chr3_+_70068440	1.324	NM_000248 NM_001184968 NM_198158 NM_198178	MITF	microphthalmia-associated transcription factor
chr12_-_9159742	1.253		A2M	alpha-2-macroglobulin
chr20_+_43468617	1.172	NM_001048223 NM_001048224	DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr3_+_50281582	1.151		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr6_-_125664770	1.131		HDDC2	HD domain containing 2
chr12_-_120781002	1.130	NM_002150	HPD	4-hydroxyphenylpyruvate dioxygenase
chr1_+_148089251	1.107	NM_001040874 NM_003516	HIST2H2AA4 HIST2H2AA3	histone cluster 2, H2aa4 histone cluster 2, H2aa3
chr2_-_200033445	1.100		SATB2	SATB homeobox 2
chr9_-_99994704	1.099	NM_052820	CORO2A	coronin, actin binding protein, 2A
chrX_-_151653756	1.089	NM_001166386 NM_001166387 NM_005367	MAGEA12	melanoma antigen family A, 12
chr1_-_27113018	1.060	NM_021969	NR0B2	nuclear receptor subfamily 0, group B, member 2
chr7_-_150283794	1.046	NM_172057	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_+_143858428	1.024	NM_001172312	PLS1	plastin 1
chr10_-_101180191	1.019	NM_002079	GOT1	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chr1_-_205290921	0.999	NM_018566	YOD1	YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr18_+_59295123	0.977	NM_002639	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr6_+_31731647	0.971	NM_019101	APOM	apolipoprotein M
chr12_-_52975777	0.948	NM_006163	NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr7_+_100037817	0.948	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr6_-_43135092	0.941	NM_015950	MRPL2	mitochondrial ribosomal protein L2
chr6_+_27208763	0.922	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr6_+_31731667	0.921		APOM	apolipoprotein M
chr22_+_19458378	0.914	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr6_+_30964441	0.912	NM_013994	DDR1	discoidin domain receptor tyrosine kinase 1
chr6_+_26266311	0.903	NM_021063 NM_138720	HIST1H2BD	histone cluster 1, H2bd
chr18_-_17538624	0.903		ABHD3	abhydrolase domain containing 3
chr19_-_60664860	0.903	NM_001136201 NM_001136202 NM_024710	ISOC2	isochorismatase domain containing 2
chr6_-_125664913	0.901	NM_016063	HDDC2	HD domain containing 2
chr5_+_176449156	0.900	NM_022963	FGFR4	fibroblast growth factor receptor 4
chrX_+_151617900	0.898	NM_005363 NM_175868	MAGEA6	melanoma antigen family A, 6
chr19_-_62028185	0.893	NM_001146186	PEG3	paternally expressed 3
chr6_+_27883877	0.890	NM_003509	HIST1H2AI HIST1H3F	histone cluster 1, H2ai histone cluster 1, H3f
chr1_-_43196911	0.885		SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr6_-_27222556	0.885	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr12_-_52975823	0.868		NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr18_-_17538735	0.867	NM_138340	ABHD3	abhydrolase domain containing 3
chr3_-_45242072	0.864		TMEM158	transmembrane protein 158 (gene/pseudogene)
chrX_-_39921525	0.857	NM_001123383 NM_001123384	BCOR	BCL6 corepressor
chr1_-_148124738	0.854	NM_003528	HIST2H2BE	histone cluster 2, H2be
chrX_-_137649180	0.841	NM_033642	FGF13	fibroblast growth factor 13
chr1_-_159459814	0.840		APOA2	apolipoprotein A-II
chr7_-_100077072	0.839	NM_003227	TFR2	transferrin receptor 2
chr2_-_224611568	0.836	NM_001136530	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr3_-_49435114	0.833	NM_000481 NM_001164710 NM_001164711 NM_001164712	AMT	aminomethyltransferase
chr16_-_28515868	0.833	NM_001054	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr1_-_143708467	0.831	NM_001195260	PDE4DIP	phosphodiesterase 4D interacting protein
chrX_+_151653874	0.822	NM_001102576 NM_153478	CSAG1	chondrosarcoma associated gene 1
chrX_-_105169370	0.821	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr11_-_8788765	0.808	NM_213618	ST5	suppression of tumorigenicity 5
chr12_-_51585004	0.799	NM_002273	KRT8	keratin 8
chr1_-_43197123	0.796		SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr2_-_88208650	0.781	NM_001443	FABP1	fatty acid binding protein 1, liver
chr17_-_53849888	0.777		RNF43	ring finger protein 43
chr6_+_111242516	0.768		AMD1	adenosylmethionine decarboxylase 1
chr6_+_31976754	0.766	NM_001178063	C2	complement component 2
chrX_+_37429927	0.760	NM_021083	XK	X-linked Kx blood group (McLeod syndrome)
chr11_+_118463906	0.753	NM_001024382	HMBS	hydroxymethylbilane synthase
chr15_+_41672543	0.750	NM_020990	CKMT1B CKMT1A	creatine kinase, mitochondrial 1B creatine kinase, mitochondrial 1A
chr11_-_5212168	0.748	NM_000519	HBD	hemoglobin, delta
chr20_+_43470354	0.739		DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr17_-_23928041	0.738		ALDOC	aldolase C, fructose-bisphosphate
chr12_+_7038240	0.735	NM_001734 NM_201442	C1S	complement component 1, s subcomponent
chr1_+_46413335	0.734	NM_005727	TSPAN1	tetraspanin 1
chr17_-_53849929	0.732	NM_017763	RNF43	ring finger protein 43
chr8_-_145090045	0.719	NM_201382	PLEC	plectin
chr8_+_38877909	0.714	NM_021623	PLEKHA2	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr3_-_197293331	0.712		TFRC	transferrin receptor (p90, CD71)
chrX_+_48529905	0.710	NM_002049	GATA1	GATA binding protein 1 (globin transcription factor 1)
chr11_-_117718532	0.703	NM_000732 NM_001040651	CD3D	CD3d molecule, delta (CD3-TCR complex)
chr17_-_23928048	0.703	NM_005165	ALDOC	aldolase C, fructose-bisphosphate
chr19_-_40728710	0.702		LOC100506469	hypothetical LOC100506469
chr12_-_7935010	0.696		SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr6_-_27968906	0.692	NM_003514	HIST1H2AM	histone cluster 1, H2am
chr8_+_145221973	0.691		CYC1	cytochrome c-1
chr14_-_104332895	0.690		AKT1	v-akt murine thymoma viral oncogene homolog 1
chr17_+_24394281	0.690		PIPOX	pipecolic acid oxidase
chr12_-_116021473	0.687	NM_001168325 NM_017899	TESC	tescalcin
chr10_+_80777234	0.684		PPIF	peptidylprolyl isomerase F
chr12_-_51132129	0.683	NM_005555	KRT6B	keratin 6B
chr6_-_27208507	0.682	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr2_-_65512619	0.668		SPRED2	sprouty-related, EVH1 domain containing 2
chr4_-_40212670	0.663	NM_019027	RBM47	RNA binding motif protein 47
chr17_+_1595012	0.663		SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr17_-_77638264	0.663		FASN	fatty acid synthase
chr10_+_80777199	0.662	NM_005729	PPIF	peptidylprolyl isomerase F
chr3_+_50281309	0.658		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr16_+_142853	0.653	NM_005332	HBZ	hemoglobin, zeta
chr12_+_52708460	0.653	NM_004503	HOXC6	homeobox C6
chr14_-_93829347	0.653	NM_001100607	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr3_+_185355947	0.652	NM_004423	DVL3	dishevelled, dsh homolog 3 (Drosophila)
chr6_-_26307418	0.651	NM_021065 NM_003530	HIST1H2AD HIST1H3D	histone cluster 1, H2ad histone cluster 1, H3d
chr12_-_74710741	0.648		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr16_-_2663375	0.646
chr17_-_23927973	0.638		ALDOC	aldolase C, fructose-bisphosphate
chr6_+_20510019	0.638	NM_001949	E2F3	E2F transcription factor 3
chr19_-_4486202	0.637	NM_001013706	PLIN5	perilipin 5
chr6_+_43846735	0.633		VEGFA	vascular endothelial growth factor A
chr1_+_2026014	0.632	NM_001033582	PRKCZ	protein kinase C, zeta
chr13_-_51483473	0.628	NM_000053 NM_001005918	ATP7B	ATPase, Cu++ transporting, beta polypeptide
chr3_+_134947788	0.625		TF	transferrin
chr14_+_30413393	0.624	NM_001135058 NM_004086	COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)
chr17_-_36928604	0.621	NM_002275	KRT15	keratin 15
chr17_-_53847937	0.620		RNF43	ring finger protein 43
chr8_-_108579270	0.617	NM_001146	ANGPT1	angiopoietin 1
chr3_+_134947940	0.608		TF	transferrin
chr3_-_197293355	0.606	NM_003234	TFRC	transferrin receptor (p90, CD71)
chr8_-_18585721	0.606		PSD3	pleckstrin and Sec7 domain containing 3
chr17_-_46296376	0.606	NM_005749	TOB1	transducer of ERBB2, 1
chr7_-_132131742	0.604		CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3
chr3_+_12367993	0.601	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr20_-_44713466	0.601	NM_001193339 NM_001193342 NM_022829	SLC13A3	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr7_+_29486010	0.600	NM_001039936	CHN2	chimerin (chimaerin) 2
chr5_-_74198370	0.600	NM_015566	FAM169A	family with sequence similarity 169, member A
chr2_-_175754366	0.599	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr3_+_134947894	0.595		TF	transferrin
chr2_-_238164042	0.594		RAB17	RAB17, member RAS oncogene family
chr8_-_17787342	0.589		FGL1	fibrinogen-like 1
chr19_-_60360768	0.588	NM_000363	TNNI3	troponin I type 3 (cardiac)
chr11_-_118739838	0.586		USP2	ubiquitin specific peptidase 2
chr16_+_70646008	0.584	NM_001126102 NM_005143	HP	haptoglobin
chr19_+_11211282	0.583	NM_018687	LOC55908	hepatocellular carcinoma-associated gene TD26
chr8_-_17812151	0.581
chr5_-_72780107	0.575	NM_004472	FOXD1	forkhead box D1
chr6_+_24603145	0.574	NM_001080 NM_170740	ALDH5A1	aldehyde dehydrogenase 5 family, member A1
chr12_-_28016182	0.573	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr11_+_7463175	0.570	NM_198474	OLFML1	olfactomedin-like 1
chr5_+_125828685	0.569	NM_001146322	GRAMD3	GRAM domain containing 3
chr6_+_26232351	0.569	NM_003512	HIST1H2AC	histone cluster 1, H2ac
chr5_+_119827903	0.565	NM_016644	PRR16	proline rich 16
chr3_+_10265357	0.560		TATDN2	TatD DNase domain containing 2
chr7_-_72360722	0.558	NM_001168347 NM_001168348 NM_018044 NM_148956	NSUN5	NOP2/Sun domain family, member 5
chr3_+_50279993	0.555	NM_001005914 NM_004636	SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr12_+_100615530	0.554	NM_020244	CHPT1	choline phosphotransferase 1
chr2_-_37312199	0.550	NM_005760	CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta
chr13_-_110011866	0.546	NM_017817	RAB20	RAB20, member RAS oncogene family
chr7_-_16471817	0.544	NM_015464	SOSTDC1	sclerostin domain containing 1
chr5_+_119827797	0.543		PRR16	proline rich 16
chr20_-_33463174	0.536		UQCC	ubiquinol-cytochrome c reductase complex chaperone
chr11_-_118740069	0.536	NM_171997	USP2	ubiquitin specific peptidase 2
chr1_-_143706300	0.534	NM_001002812 NM_014644 NM_001002810 NM_001198834 NM_001195261	PDE4DIP	phosphodiesterase 4D interacting protein
chr17_+_77289804	0.533		SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr1_-_200396328	0.532		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr17_+_38306339	0.531	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr7_+_94130752	0.530		PEG10	paternally expressed 10
chr3_-_197293394	0.528	NM_001128148	TFRC	transferrin receptor (p90, CD71)
chr19_+_11510578	0.525	NM_001299	CNN1	calponin 1, basic, smooth muscle
chrX_-_13745108	0.524		GPM6B	glycoprotein M6B
chr20_-_33463194	0.521	NM_001184977 NM_018244 NM_199487	UQCC	ubiquinol-cytochrome c reductase complex chaperone
chr17_+_77289775	0.510	NM_012140	SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr10_+_102722275	0.508	NM_017893	SEMA4G	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr9_-_137992967	0.506	NM_016172	UBAC1	UBA domain containing 1
chr11_+_22652894	0.506	NM_005256	GAS2	growth arrest-specific 2
chr3_-_50624085	0.503		CISH	cytokine inducible SH2-containing protein
chr21_+_43963597	0.502		PDXK	pyridoxal (pyridoxine, vitamin B6) kinase
chr6_+_27914301	0.502	NM_003520	HIST1H2BN	histone cluster 1, H2bn
chrX_-_13744933	0.500		GPM6B	glycoprotein M6B
chr3_-_49701085	0.499	NM_020998	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)
chr20_-_2589476	0.498		IDH3B	isocitrate dehydrogenase 3 (NAD+) beta
chr8_-_17811750	0.492		FGL1	fibrinogen-like 1
chr22_+_17800018	0.492	NM_003776	MRPL40	mitochondrial ribosomal protein L40
chr12_+_6768966	0.488		CD4	CD4 molecule
chr22_+_43451351	0.486	NM_001017530 NM_001198721 NM_015366	PRR5	proline rich 5 (renal)
chrX_+_148671394	0.486	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr16_-_51138306	0.486	NM_001080430	TOX3	TOX high mobility group box family member 3
chr2_+_97628929	0.485	NM_001862	COX5B	cytochrome c oxidase subunit Vb
chr4_+_74520796	0.484	NM_001134	AFP	alpha-fetoprotein
chr2_-_203484445	0.484		WDR12	WD repeat domain 12
chr20_-_33705244	0.484	NM_003915	CPNE1	copine I
chrX_+_151633730	0.481	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chr8_-_110726201	0.481	NM_001099753 NM_001099754 NM_001099755	SYBU	syntabulin (syntaxin-interacting)
chr20_-_31452964	0.479		CDK5RAP1	CDK5 regulatory subunit associated protein 1
chr6_+_27222839	0.478	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr19_-_17217022	0.477	NM_005234	NR2F6	nuclear receptor subfamily 2, group F, member 6
chr9_-_115880494	0.476	NM_001633	AMBP	alpha-1-microglobulin/bikunin precursor
chr18_-_12367209	0.472		AFG3L2	AFG3 ATPase family gene 3-like 2 (S. cerevisiae)
chr15_+_41772375	0.471	NM_001015001	CKMT1A	creatine kinase, mitochondrial 1A
chr20_+_29656744	0.466	NM_002165 NM_181353	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr2_-_238164452	0.465	NM_022449	RAB17	RAB17, member RAS oncogene family
chr2_+_28971007	0.464	NM_015131	WDR43	WD repeat domain 43

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.95	5.84e-07	GO:0022904	respiratory electron transport chain
2.60	2.48e-06	GO:0045333	cellular respiration
1.96	6.68e-05	GO:0015980	energy derivation by oxidation of organic compounds
2.38	1.79e-04	GO:0022900	electron transport chain
1.72	7.86e-04	GO:0006091	generation of precursor metabolites and energy
1.17	9.92e-04	GO:0032501	multicellular organismal process
2.39	4.92e-03	GO:0034728	nucleosome organization
2.57	7.34e-03	GO:0006839	mitochondrial transport
2.42	1.13e-02	GO:0006334	nucleosome assembly
2.37	1.94e-02	GO:0031497	chromatin assembly
1.11	2.28e-02	GO:0008152	metabolic process
1.40	2.91e-02	GO:0055114	oxidation-reduction process
3.83	3.66e-02	GO:0046470	phosphatidylcholine metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.71	4.21e-08	GO:0044429	mitochondrial part
2.03	1.54e-07	GO:0005743	mitochondrial inner membrane
3.51	2.14e-07	GO:0000786	nucleosome
1.83	2.64e-07	GO:0005740	mitochondrial envelope
1.84	3.92e-07	GO:0031966	mitochondrial membrane
1.94	7.24e-07	GO:0019866	organelle inner membrane
1.59	5.48e-06	GO:0031967	organelle envelope
1.58	7.98e-06	GO:0031975	envelope
2.36	9.87e-05	GO:0044455	mitochondrial membrane part
2.50	2.25e-04	GO:0032993	protein-DNA complex
1.35	8.26e-04	GO:0005739	mitochondrion
5.10	8.76e-03	GO:0005833	hemoglobin complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
5.26	2.93e-03	GO:0005344	oxygen transporter activity