Motif ID: NHLH1,2.p2

Z-value: 2.113


Transcription factors associated with NHLH1,2.p2:

Gene SymbolEntrez IDGene Name
NHLH1 4807 nescient helix loop helix 1
NHLH2 4808 nescient helix loop helix 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NHLH2chr1_-_1161848460.401.2e-01Click!
NHLH1chr1_+_158603480-0.194.8e-01Click!


Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_113546841 4.628 NM_000820
 GAS6
growth arrest-specific 6
chr10_+_17311283 4.281 VIM
vimentin
chr10_+_17311307 4.264 VIM
vimentin
chr10_+_17311242 4.254 VIM
vimentin
chr10_+_17311282 4.127 VIM
vimentin
chr10_+_17311347 4.118 VIM
vimentin
chr13_+_113546897 3.953 GAS6
growth arrest-specific 6
chr14_-_51605487 3.918 NID2
nidogen 2 (osteonidogen)
chr13_+_113546943 3.836 GAS6
growth arrest-specific 6
chrX_-_13866451 3.786 GPM6B
glycoprotein M6B
chr4_-_57671307 3.689 IGFBP7
insulin-like growth factor binding protein 7
chr11_-_6298284 3.581 NM_145040
 PRKCDBP
protein kinase C, delta binding protein
chr14_-_51605461 3.561 NID2
nidogen 2 (osteonidogen)
chr14_-_51605515 3.448 NID2
nidogen 2 (osteonidogen)
chr9_-_35679799 3.328 TPM2
tropomyosin 2 (beta)
chr2_-_229844198 3.311 NM_001100818
NM_017933
 PID1

phosphotyrosine interaction domain containing 1

chr4_-_57671273 3.149 NM_001553
 IGFBP7
insulin-like growth factor binding protein 7
chr9_-_35679902 3.088 NM_003289
NM_213674
 TPM2

tropomyosin 2 (beta)

chr10_+_124211353 2.990 HTRA1
HtrA serine peptidase 1
chr7_+_129919157 2.825 NM_002402
 MEST
mesoderm specific transcript homolog (mouse)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
enrichment   p-value GO term description
1.53 4.18e-03 GO:0007409 axonogenesis
1.52 5.00e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.51 5.84e-03 GO:0048812 neuron projection morphogenesis
1.49 3.43e-03 GO:0048858 cell projection morphogenesis
1.48 6.01e-03 GO:0032990 cell part morphogenesis
1.46 1.79e-02 GO:0000904 cell morphogenesis involved in differentiation
1.46 2.35e-02 GO:0031175 neuron projection development
1.42 4.87e-05 GO:0048468 cell development
1.42 2.24e-02 GO:0000902 cell morphogenesis
1.41 1.34e-04 GO:0022008 neurogenesis
1.41 1.79e-02 GO:0030030 cell projection organization
1.41 4.32e-02 GO:0048666 neuron development
1.40 8.58e-04 GO:0048699 generation of neurons
1.40 2.93e-02 GO:0032989 cellular component morphogenesis
1.38 3.05e-02 GO:0030182 neuron differentiation
1.30 5.01e-04 GO:0009653 anatomical structure morphogenesis
1.29 8.47e-04 GO:0007399 nervous system development
1.29 3.88e-02 GO:0010646 regulation of cell communication
1.27 3.47e-05 GO:0048869 cellular developmental process
1.27 7.74e-05 GO:0030154 cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.23 1.97e-02 GO:0005856 cytoskeleton
1.10 1.76e-05 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.62 7.04e-04 GO:0003779 actin binding
1.39 3.86e-02 GO:0008092 cytoskeletal protein binding