Motif ID: STAT1,3.p3

Z-value: 1.072


Transcription factors associated with STAT1,3.p3:

Gene SymbolEntrez IDGene Name
STAT1 6772 signal transducer and activator of transcription 1, 91kDa
STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT1chr2_-_1915871270.467.2e-02Click!
STAT3chr17_-_37794017-0.322.2e-01Click!


Activity profile for motif STAT1,3.p3.

activity profile for motif STAT1,3.p3


Sorted Z-values histogram for motif STAT1,3.p3

Sorted Z-values for motif STAT1,3.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1,3.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_54072969 7.971 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_+_113672378 5.130 NNMT
nicotinamide N-methyltransferase
chr11_+_113672407 5.073 NNMT
nicotinamide N-methyltransferase
chr10_-_90740935 3.966 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr19_+_39860398 2.643 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr1_-_201422450 2.156 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_201422436 1.720 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_201422533 1.649 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr10_+_90741024 1.354 FAS
Fas (TNF receptor superfamily, member 6)
chr1_-_201422490 1.235 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr6_+_36754433 1.077 NM_000389
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr6_+_36754467 1.077 CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr1_-_143706300 1.070 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr1_-_201422368 1.031 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr20_-_42713663 0.935 ADA
adenosine deaminase
chr4_-_129429433 0.927 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr3_-_15875932 0.870 NM_015199
ANKRD28
ankyrin repeat domain 28
chr11_+_32068990 0.802 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr15_+_30797466 0.732 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr1_-_143706265 0.717 PDE4DIP
phosphodiesterase 4D interacting protein
chr2_+_170074457 0.688 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr1_+_154351200 0.668 LMNA
lamin A/C
chr9_+_131937163 0.663 GPR107
G protein-coupled receptor 107
chr10_+_91142301 0.607 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr1_+_24944346 0.602 NM_013943
CLIC4
chloride intracellular channel 4
chr5_+_134237325 0.582 NM_024715
TXNDC15
thioredoxin domain containing 15
chr1_-_157313179 0.576 NM_004833
AIM2
absent in melanoma 2
chr11_+_32069183 0.557 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr1_-_56750235 0.532 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_143706196 0.531 PDE4DIP
phosphodiesterase 4D interacting protein
chr14_+_66777578 0.518 NM_022474
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr5_-_138753443 0.506 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr9_-_74757735 0.454 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr4_+_126457016 0.440 NM_024582
FAT4
FAT tumor suppressor homolog 4 (Drosophila)
chrX_+_46318135 0.432 NM_019886
CHST7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr14_-_67211081 0.431 NM_006370
VTI1B
vesicle transport through interaction with t-SNAREs homolog 1B (yeast)
chr5_-_111340421 0.430 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr5_+_149867866 0.426 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr12_-_122322117 0.405 NM_004642
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr3_+_133798770 0.400 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr12_+_100795213 0.371 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr16_-_24876357 0.364 ARHGAP17
Rho GTPase activating protein 17
chr14_-_91483757 0.345 NM_006329
FBLN5
fibulin 5
chr11_-_605920 0.327 IRF7
interferon regulatory factor 7
chr6_-_27548438 0.326 NM_007149
ZNF184
zinc finger protein 184
chr1_-_158883666 0.316 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr1_+_111571803 0.314 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr8_-_58068697 0.314 IMPAD1
inositol monophosphatase domain containing 1
chr11_+_7574992 0.311 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr3_+_23962518 0.308 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chrX_+_48317772 0.307 NM_006743
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr8_-_58068977 0.303 NM_017813
IMPAD1
inositol monophosphatase domain containing 1
chr11_-_62218759 0.294 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_-_132764257 0.290 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr13_-_94751573 0.285 NM_001105515
NM_005845
ABCC4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr17_+_73694992 0.268 NM_001010982
NM_001145526
AFMID

arylformamidase

chr1_-_54291474 0.267 TMEM59
transmembrane protein 59
chr1_-_54291378 0.267 TMEM59
transmembrane protein 59
chr8_-_58068956 0.264 IMPAD1
inositol monophosphatase domain containing 1
chr19_+_49198916 0.257 NM_006300
ZNF230
zinc finger protein 230
chr1_+_194887630 0.252 NM_000186
NM_001014975
CFH

complement factor H

chr11_-_605998 0.240 NM_001572
NM_004029
IRF7

interferon regulatory factor 7

chr3_-_81893604 0.236 NM_000158
GBE1
glucan (1,4-alpha-), branching enzyme 1
chr3_-_81893308 0.228 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr4_+_41235077 0.226 LIMCH1
LIM and calponin homology domains 1
chr10_+_85994788 0.215 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr11_-_605649 0.215 NM_004031
IRF7
interferon regulatory factor 7
chr2_-_85948287 0.208 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_-_54291503 0.202 TMEM59
transmembrane protein 59
chr15_+_88609837 0.201 NM_001033088
NGRN
neugrin, neurite outgrowth associated
chr14_+_23905984 0.201 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr3_-_81893506 0.198 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr9_-_23811477 0.191 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr3_-_135575925 0.189 NM_016201
AMOTL2
angiomotin like 2
chr8_+_1759502 0.187 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr1_-_161380562 0.182 RGS5
regulator of G-protein signaling 5
chr9_-_88751923 0.182 NM_002048
GAS1
growth arrest-specific 1
chr16_+_66129481 0.181 FAM65A
family with sequence similarity 65, member A
chr10_+_93548162 0.179 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr17_+_5913149 0.176 WSCD1
WSC domain containing 1
chr8_-_58068930 0.174 IMPAD1
inositol monophosphatase domain containing 1
chr22_-_22426551 0.166 NM_013378
VPREB3
pre-B lymphocyte 3
chr3_+_137224266 0.160 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr17_+_29606408 0.160 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr8_-_18710575 0.151 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr15_-_41589958 0.139 NM_005657
TP53BP1
tumor protein p53 binding protein 1
chr11_+_834111 0.138 TSPAN4
tetraspanin 4
chr1_+_148137778 0.131 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr2_+_20510312 0.126 NM_004040
RHOB
ras homolog gene family, member B
chr6_+_97117144 0.123 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr22_+_16501540 0.123 BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr1_-_54291634 0.121 NM_004872
TMEM59
transmembrane protein 59
chrX_-_134013644 0.121 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr7_-_107883929 0.120 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr22_-_49041786 0.120 MAPK12
mitogen-activated protein kinase 12
chr1_-_154226484 0.117 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr5_-_133734616 0.114 CDKL3
cyclin-dependent kinase-like 3
chr8_+_27238979 0.113 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr10_+_70699761 0.111 NM_033497
NM_033498
NM_033500
HK1


hexokinase 1


chr12_-_52356375 0.110 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr3_+_48456708 0.107 CCDC72
coiled-coil domain containing 72
chr11_-_64247230 0.105 NM_015080
NM_138732
NRXN2

neurexin 2

chr1_-_153213483 0.102 NM_001130041
NM_003029
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr22_+_16501446 0.101 NM_015367
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr19_+_49248003 0.100 NM_013361
ZNF223
zinc finger protein 223
chr1_-_153213454 0.098 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr12_+_66328760 0.097 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr12_-_54869511 0.097 SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr20_-_47618059 0.096 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr12_-_107238568 0.096 NM_001142345
CMKLR1
chemokine-like receptor 1
chr1_-_42402973 0.096 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr1_-_108536885 0.091 NM_213651
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr16_-_19803606 0.090 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr6_+_31648071 0.089 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr5_+_109053034 0.087 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr19_-_49696322 0.084 NM_013256
ZNF180
zinc finger protein 180
chr5_+_133735004 0.084 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr19_+_49221333 0.083 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr15_-_70863110 0.081 ADPGK
ADP-dependent glucokinase
chr22_-_36212160 0.081 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr14_+_77939845 0.079 NM_004796
NRXN3
neurexin 3
chr5_-_139924013 0.079 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr4_+_52403922 0.078 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr11_-_102174032 0.078 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr12_+_11694172 0.075 ETV6
ets variant 6
chr3_+_48456667 0.074 NM_015933
CCDC72
coiled-coil domain containing 72
chr1_-_25431544 0.074 NM_015484
NM_207170
SYF2

SYF2 homolog, RNA splicing factor (S. cerevisiae)

chr2_-_254037 0.073 NM_001159597
NM_015677
SH3YL1

SH3 domain containing, Ysc84-like 1 (S. cerevisiae)

chrX_+_105932536 0.066 NM_017752
NM_198881
TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr10_+_93548048 0.066 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr10_-_27483315 0.065 NM_014263
NM_139312
YME1L1

YME1-like 1 (S. cerevisiae)

chrX_-_100434700 0.063 NM_024885
TAF7L
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
chr5_-_139924229 0.062 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr19_+_49408523 0.062 NM_182490
ZNF227
zinc finger protein 227
chr16_+_4614830 0.061 MGRN1
mahogunin, ring finger 1
chr10_+_95838801 0.059 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr2_+_235525355 0.058 NM_014521
SH3BP4
SH3-domain binding protein 4
chr12_+_6893751 0.056 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chr7_-_100009205 0.054 NM_001168682
SAP25
sin3A-binding protein 25
chr19_+_49147219 0.054 NM_013359
ZNF221
zinc finger protein 221
chr15_-_70863124 0.052 ADPGK
ADP-dependent glucokinase
chr14_+_102313585 0.051 TRAF3
TNF receptor-associated factor 3
chr6_-_132875858 0.050 NM_003569
STX7
syntaxin 7
chr11_+_61204392 0.050 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr19_-_49500966 0.049 NM_004234
ZNF235
zinc finger protein 235
chr15_-_73719546 0.047 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr2_-_253982 0.047 SH3YL1
SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
chrX_+_154097894 0.045 NM_003372
VBP1
von Hippel-Lindau binding protein 1
chr17_+_39778016 0.044 NM_002087
GRN
granulin
chr6_-_28411889 0.043 NM_001135216
ZNF323
zinc finger protein 323
chr3_-_130600931 0.042 RPL32P3
ribosomal protein L32 pseudogene 3
chr16_+_66128843 0.042 NM_001193524
FAM65A
family with sequence similarity 65, member A
chr8_+_11388918 0.042 NM_001715
BLK
B lymphoid tyrosine kinase
chr19_+_62836322 0.041 NM_006385
NM_198855
ZNF211

zinc finger protein 211

chrX_-_107221405 0.039 NM_002814
NM_170750
PSMD10

proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

chr19_-_4782711 0.036 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr15_+_56217686 0.034 NM_020980
AQP9
aquaporin 9
chr10_+_93548119 0.033 NM_025235
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr2_+_17798860 0.033 NM_001130009
LOC284952
GEN1
hypothetical protein LOC284952
Gen homolog 1, endonuclease (Drosophila)
chr1_-_205186330 0.032 NM_002644
PIGR
polymeric immunoglobulin receptor
chr9_-_133574928 0.032 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr12_-_47735373 0.029 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr1_-_43606276 0.029 NM_022821
ELOVL1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr15_-_62173041 0.029 NM_001014812
NM_032231
FAM96A

family with sequence similarity 96, member A

chr3_-_171070314 0.029 NM_024727
LRRC31
leucine rich repeat containing 31
chr17_-_2977594 0.028 NM_003555
OR1G1
olfactory receptor, family 1, subfamily G, member 1
chr3_+_37259684 0.025 NM_001172713
NM_002078
GOLGA4

golgin A4

chr7_-_83662152 0.023 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr3_-_120442413 0.022 NM_003778
NM_212543
B4GALT4

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4

chr21_-_36774257 0.022 NM_001146079
NM_144492
CLDN14

claudin 14

chr17_+_68740952 0.020 C17orf80
chromosome 17 open reading frame 80
chr4_-_88032570 0.018 NM_144645
C4orf36
chromosome 4 open reading frame 36
chr5_+_179065282 0.018 CANX
calnexin
chr19_-_3935152 0.017 EEF2
eukaryotic translation elongation factor 2
chr1_+_36462625 0.017 THRAP3
thyroid hormone receptor associated protein 3
chr19_-_43412152 0.016 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr9_-_130078017 0.016 NM_004486
GOLGA2
golgin A2
chr1_+_112811562 0.015 NM_004185
WNT2B
wingless-type MMTV integration site family, member 2B
chr15_+_76228788 0.015 IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr19_+_49180171 0.015 NM_003445
NM_198089
ZNF155

zinc finger protein 155

chr19_+_49309350 0.014 NM_013362
ZNF225
zinc finger protein 225
chr17_+_39778191 0.014 GRN
granulin
chr6_-_28412130 0.013 NM_030899
ZNF323
zinc finger protein 323
chr7_+_150180510 0.012 ABP1
amiloride binding protein 1 (amine oxidase (copper-containing))
chr12_+_108399829 0.012 UBE3B
ubiquitin protein ligase E3B
chr1_-_20122638 0.010 NM_014589
PLA2G2E
phospholipase A2, group IIE
chr5_-_179431601 0.009 NM_018434
RNF130
ring finger protein 130
chr17_-_45901173 0.008 NM_001267
CHAD
chondroadherin
chr9_-_136949531 0.007 NM_002003
FCN1
ficolin (collagen/fibrinogen domain containing) 1
chr13_+_24844084 0.007 NM_016529
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr2_-_119998530 0.007 SCTR
secretin receptor
chrY_+_505078 0.007 NM_000451
NM_006883
SHOX

short stature homeobox

chrX_+_505078 0.007 NM_000451
NM_006883
SHOX

short stature homeobox

chr2_-_68238079 0.007 NM_138458
WDR92
WD repeat domain 92
chr22_+_44188263 0.006 RIBC2
RIB43A domain with coiled-coils 2
chr11_-_118471385 0.006 NM_002105
H2AFX
H2A histone family, member X
chr12_+_102848322 0.006 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr5_+_161206774 0.006 NM_000806
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr12_+_102848316 0.006 NM_003299
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr12_+_22669275 0.006 NM_001039481
NM_018638
ETNK1

ethanolamine kinase 1


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.