Motif ID: RREB1.p2

Z-value: 1.912


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RREB1chr6_+_70527980.457.9e-02Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_151688850 3.420 NM_005362
 MAGEA3
melanoma antigen family A, 3
chrX_+_151617900 3.352 NM_005363
NM_175868
 MAGEA6

melanoma antigen family A, 6

chr11_+_46359855 2.985 MDK
midkine (neurite growth-promoting factor 2)
chrX_-_151653756 2.913 NM_001166386
NM_001166387
NM_005367
 MAGEA12


melanoma antigen family A, 12


chr11_+_46359821 2.877 MDK
midkine (neurite growth-promoting factor 2)
chr11_+_46359836 2.754 MDK
midkine (neurite growth-promoting factor 2)
chrX_-_152139267 2.447 NM_004988
 MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr11_+_46359781 2.368 NM_002391
 MDK
midkine (neurite growth-promoting factor 2)
chr11_+_46359878 2.216 NM_001012333
 MDK
midkine (neurite growth-promoting factor 2)
chr19_-_60350122 2.197 TNNT1
troponin T type 1 (skeletal, slow)
chr2_-_218551786 2.163 TNS1
tensin 1
chrX_+_151653874 1.910 NM_001102576
NM_153478
 CSAG1

chondrosarcoma associated gene 1

chr20_-_22512893 1.720 FOXA2
forkhead box A2
chrX_+_151633730 1.697 NM_005361
NM_175742
NM_175743
 MAGEA2


melanoma antigen family A, 2


chr21_-_27261276 1.674 NM_007038
 ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chrX_+_152561086 1.611 NM_001395
 DUSP9
dual specificity phosphatase 9
chrX_-_137621492 1.607 NM_004114
 FGF13
fibroblast growth factor 13
chr19_-_18578577 1.567 CRLF1
cytokine receptor-like factor 1
chr19_-_18578631 1.560 NM_004750
 CRLF1
cytokine receptor-like factor 1
chr6_+_2945025 1.555 NM_000904
 NQO2
NAD(P)H dehydrogenase, quinone 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 40 entries
enrichment   p-value GO term description
1.71 2.28e-05 GO:0016568 chromatin modification
1.59 2.55e-02 GO:0060284 regulation of cell development
1.56 4.72e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.49 1.87e-03 GO:0051253 negative regulation of RNA metabolic process
1.49 2.57e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.46 4.42e-04 GO:0030182 neuron differentiation
1.45 6.24e-03 GO:0010629 negative regulation of gene expression
1.44 3.66e-02 GO:0000904 cell morphogenesis involved in differentiation
1.42 2.28e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.42 4.68e-03 GO:0045595 regulation of cell differentiation
1.42 1.55e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.41 1.58e-04 GO:0048468 cell development
1.41 1.33e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.40 4.29e-04 GO:0022008 neurogenesis
1.40 7.35e-04 GO:0048699 generation of neurons
1.40 1.05e-02 GO:0009890 negative regulation of biosynthetic process
1.40 1.14e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.40 4.70e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 2.70e-02 GO:0051254 positive regulation of RNA metabolic process
1.33 4.79e-05 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.10 1.04e-02 GO:0042627 chylomicron
1.40 7.76e-04 GO:0044451 nucleoplasm part
1.21 1.61e-03 GO:0044428 nuclear part
1.21 9.54e-03 GO:0031981 nuclear lumen
1.13 1.34e-04 GO:0005634 nucleus
1.05 4.16e-02 GO:0044424 intracellular part
1.04 4.89e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.38 9.39e-03 GO:0043565 sequence-specific DNA binding
1.31 7.58e-03 GO:0030528 transcription regulator activity
1.10 8.39e-05 GO:0005515 protein binding