Motif ID: RREB1.p2

Z-value: 1.912


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RREB1chr6_+_70527980.457.9e-02Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_151688850 3.420 NM_005362
MAGEA3
melanoma antigen family A, 3
chrX_+_151617900 3.352 NM_005363
NM_175868
MAGEA6

melanoma antigen family A, 6

chr11_+_46359855 2.985 MDK
midkine (neurite growth-promoting factor 2)
chrX_-_151653756 2.913 NM_001166386
NM_001166387
NM_005367
MAGEA12


melanoma antigen family A, 12


chr11_+_46359821 2.877 MDK
midkine (neurite growth-promoting factor 2)
chr11_+_46359836 2.754 MDK
midkine (neurite growth-promoting factor 2)
chrX_-_152139267 2.447 NM_004988
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr11_+_46359781 2.368 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr11_+_46359878 2.216 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr19_-_60350122 2.197 TNNT1
troponin T type 1 (skeletal, slow)
chr2_-_218551786 2.163 TNS1
tensin 1
chrX_+_151653874 1.910 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chr20_-_22512893 1.720 FOXA2
forkhead box A2
chrX_+_151633730 1.697 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr21_-_27261276 1.674 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chrX_+_152561086 1.611 NM_001395
DUSP9
dual specificity phosphatase 9
chrX_-_137621492 1.607 NM_004114
FGF13
fibroblast growth factor 13
chr19_-_18578577 1.567 CRLF1
cytokine receptor-like factor 1
chr19_-_18578631 1.560 NM_004750
CRLF1
cytokine receptor-like factor 1
chr6_+_2945025 1.555 NM_000904
NQO2
NAD(P)H dehydrogenase, quinone 2
chr7_-_45927263 1.538 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chrX_-_151672985 1.497 NM_005361
NM_175742
NM_175743
MAGEA2


melanoma antigen family A, 2


chr19_-_60350118 1.463 TNNT1
troponin T type 1 (skeletal, slow)
chr19_-_18578467 1.443 CRLF1
cytokine receptor-like factor 1
chr19_-_60352369 1.440 NM_001126132
NM_001126133
NM_003283
TNNT1


troponin T type 1 (skeletal, slow)


chr16_+_84202515 1.409 NM_001134473
KIAA0182
KIAA0182
chrX_-_137621060 1.371 FGF13
fibroblast growth factor 13
chr21_-_43368963 1.356 NM_000071
CBS
cystathionine-beta-synthase
chr21_-_43369492 1.318 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr1_-_159459814 1.214 APOA2
apolipoprotein A-II
chr11_-_2108035 1.197 IGF2
insulin-like growth factor 2 (somatomedin A)
chrX_-_39841599 1.193 NM_001123385
NM_017745
BCOR

BCL6 corepressor

chr19_+_811615 1.178 CFD
complement factor D (adipsin)
chr3_-_187025501 1.157 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr7_+_93861808 1.148 NM_000089
COL1A2
collagen, type I, alpha 2
chr11_-_74740298 1.130 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr6_-_6265896 1.127 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr2_-_128149112 1.116 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr22_-_21231421 1.103 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr11_-_2115086 1.096 IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_1283770 1.091 NM_032348
MXRA8
matrix-remodelling associated 8
chr20_-_22513050 1.059 NM_021784
FOXA2
forkhead box A2
chr2_+_8739563 1.014 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr7_-_150305933 0.995 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr10_-_75085754 0.982 NM_001114133
SYNPO2L
synaptopodin 2-like
chr6_-_6265874 0.968 F13A1
coagulation factor XIII, A1 polypeptide
chr16_-_28515868 0.963 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr5_+_176446425 0.940 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr12_+_69046241 0.934 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chrX_+_51944658 0.931 NM_001098800
NM_030801
NM_177535
NM_177537
MAGED4
MAGED4B


melanoma antigen family D, 4
melanoma antigen family D, 4B


chr12_-_54387732 0.915 ITGA7
integrin, alpha 7
chr16_-_28528780 0.895 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr1_+_21708428 0.894 NM_000478
NM_001127501
NM_001177520
ALPL


alkaline phosphatase, liver/bone/kidney


chrY_+_13526169 0.891 DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr3_-_187025438 0.886 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_-_220144511 0.875 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr16_+_84204424 0.873 NM_014615
KIAA0182
KIAA0182
chrX_-_151037066 0.854 NM_021049
MAGEA5
melanoma antigen family A, 5
chr6_+_32229771 0.851 PPT2-EGFL8
PPT2
PPT2-EGFL8 read-through transcript
palmitoyl-protein thioesterase 2
chr16_+_30118036 0.843 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chrX_-_101658297 0.835 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr19_-_18409788 0.828 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr18_-_24011349 0.814 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr12_-_52980984 0.809 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr12_-_52980914 0.809 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr7_-_143230096 0.798 NM_014719
FAM115A
family with sequence similarity 115, member A
chr17_+_16225130 0.792


chr6_+_32230172 0.791 PPT2
palmitoyl-protein thioesterase 2
chr22_+_43442987 0.787 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr10_+_5444516 0.783 NM_001047160
NET1
neuroepithelial cell transforming 1
chr10_-_95350949 0.780 NM_006744
RBP4
retinol binding protein 4, plasma
chr12_+_54832470 0.779 NM_002475
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chrX_-_148476903 0.776 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chrX_-_153534951 0.765 NM_020994
NM_172377
CTAG2

cancer/testis antigen 2

chrY_+_13526092 0.764 NM_004660
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr11_-_118799058 0.761 THY1
Thy-1 cell surface antigen
chr18_+_32021418 0.744 NM_017947
MOCOS
molybdenum cofactor sulfurase
chr19_-_18409971 0.744 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr11_-_2109536 0.744 IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_50697355 0.731 HLF
hepatic leukemia factor
chr10_-_725522 0.730 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr7_+_73506047 0.729 NM_016328
GTF2IRD1
GTF2I repeat domain containing 1
chr14_+_100270222 0.723 DLK1
delta-like 1 homolog (Drosophila)
chr7_+_102340579 0.720 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr2_-_220144427 0.718 OBSL1
obscurin-like 1
chr6_-_46566969 0.714 RCAN2
regulator of calcineurin 2
chr19_+_659766 0.713 NM_001040134
NM_002579
PALM

paralemmin

chr14_-_20563698 0.709 NDRG2
NDRG family member 2
chr2_-_200030944 0.704 NM_001172509
SATB2
SATB homeobox 2
chr12_+_56135353 0.703 NM_031479
INHBE
inhibin, beta E
chr7_+_73506172 0.698 GTF2IRD1
GTF2I repeat domain containing 1
chr11_-_34336102 0.697 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr18_-_24010944 0.689 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr12_-_54387934 0.682 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chrX_-_11194015 0.678 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr2_+_5750229 0.676 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chrX_+_148671394 0.672 NM_005365
NM_001080790
MAGEA9
MAGEA9B
melanoma antigen family A, 9
melanoma antigen family A, 9B
chr7_-_150306169 0.666 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_-_85816520 0.666 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr14_-_21064182 0.663 SALL2
sal-like 2 (Drosophila)
chr20_+_34206070 0.655 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr14_-_20563722 0.649 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr17_+_44927591 0.647 NM_002507
NGFR
nerve growth factor receptor
chr1_-_38243716 0.647 FHL3
four and a half LIM domains 3
chr16_+_29378694 0.643 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr17_+_77582774 0.642 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr7_-_92303812 0.639 CDK6
cyclin-dependent kinase 6
chr19_+_14405216 0.637 PKN1
protein kinase N1
chr5_-_39460687 0.637 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_-_32574185 0.631 NM_023009
MARCKSL1
MARCKS-like 1
chr17_+_50697319 0.628 NM_002126
HLF
hepatic leukemia factor
chr21_+_46367216 0.628 COL6A2
collagen, type VI, alpha 2
chr17_-_72218535 0.616 NM_001008528
NM_001008529
NM_198530
MXRA7


matrix-remodelling associated 7


chr10_+_114699953 0.604 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr3_+_8750485 0.601 NM_033337
NM_001234
CAV3

caveolin 3

chr11_-_118799452 0.600 NM_006288
THY1
Thy-1 cell surface antigen
chr1_-_38243747 0.599 NM_004468
FHL3
four and a half LIM domains 3
chrX_-_153500584 0.596 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr20_-_47238082 0.590 STAU1
staufen, RNA binding protein, homolog 1 (Drosophila)
chr4_-_5941043 0.586 CRMP1
collapsin response mediator protein 1
chrX_+_153466611 0.582 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr17_-_72218661 0.580 MXRA7
matrix-remodelling associated 7
chr1_-_159459999 0.580 NM_001643
APOA2
apolipoprotein A-II
chr7_-_149669622 0.580 NM_002889
RARRES2
retinoic acid receptor responder (tazarotene induced) 2
chr1_+_212227902 0.579 PROX1
prospero homeobox 1
chr2_-_227372574 0.578 IRS1
insulin receptor substrate 1
chr19_+_876984 0.574 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr17_-_7023283 0.573 ASGR1
asialoglycoprotein receptor 1
chr5_-_176833197 0.573 DBN1
drebrin 1
chr17_-_77474597 0.570 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr3_+_51984076 0.557 NM_015407
ABHD14A-ACY1
ABHD14A
ABHD14A-ACY1 read-through transcript
abhydrolase domain containing 14A
chr7_-_92303865 0.555 NM_001145306
CDK6
cyclin-dependent kinase 6
chr10_-_76538859 0.554 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr1_-_21850874 0.548 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr19_-_50977485 0.547 DMPK
dystrophia myotonica-protein kinase
chr7_-_100077072 0.546 NM_003227
TFR2
transferrin receptor 2
chr11_+_124539768 0.544 NM_022062
PKNOX2
PBX/knotted 1 homeobox 2
chr13_+_112808102 0.544 NM_000131
NM_019616
F7

coagulation factor VII (serum prothrombin conversion accelerator)

chr2_-_119322228 0.540 NM_001426
EN1
engrailed homeobox 1
chr2_-_161058550 0.538 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr1_-_154214522 0.533 NM_004723
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr3_+_139550368 0.533 MRAS
muscle RAS oncogene homolog
chr19_+_50141068 0.532 NM_000483
APOC2
apolipoprotein C-II
chr17_-_44058612 0.527 NM_024017
HOXB9
homeobox B9
chr6_-_35572694 0.524 NM_003214
TEAD3
TEA domain family member 3
chr20_+_30813851 0.513 NM_006892
NM_175848
NM_175849
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr1_-_149214063 0.509 NM_022075
NM_181746
LASS2

LAG1 homolog, ceramide synthase 2

chr19_-_50977592 0.509 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr11_+_46358909 0.503 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr15_+_61122139 0.503 TPM1
tropomyosin 1 (alpha)
chr10_+_22650145 0.502 BMI1
BMI1 polycomb ring finger oncogene
chr1_-_149213916 0.499 LASS2
LAG1 homolog, ceramide synthase 2
chr16_+_70217564 0.499 NM_001017967
NM_052858
MARVELD3

MARVEL domain containing 3

chr12_+_55808514 0.498 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr12_-_6586811 0.497 NM_001273
CHD4
chromodomain helicase DNA binding protein 4
chr11_+_124539814 0.496 PKNOX2
PBX/knotted 1 homeobox 2
chrX_+_152562013 0.496 DUSP9
dual specificity phosphatase 9
chr6_+_33486750 0.494 NM_002636
NM_024165
PHF1

PHD finger protein 1

chr7_-_130891861 0.491 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr7_+_65731289 0.489 NM_001167961
NM_153033
KCTD7

potassium channel tetramerisation domain containing 7

chr3_+_12304332 0.489 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr11_-_8695974 0.489 ST5
suppression of tumorigenicity 5
chr2_-_144994349 0.487 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr21_+_42946719 0.486 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr20_+_30814048 0.483 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr12_-_69600514 0.479 PTPRR
protein tyrosine phosphatase, receptor type, R
chr9_-_126945536 0.479 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr4_-_186693574 0.478 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr1_-_149213929 0.478 LASS2
LAG1 homolog, ceramide synthase 2
chr7_-_19123787 0.476 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr3_+_156280338 0.475 NM_007287
MME
membrane metallo-endopeptidase
chr6_-_2916980 0.474 SERPINB6
serpin peptidase inhibitor, clade B (ovalbumin), member 6
chr2_-_128149800 0.473 LIMS2
LIM and senescent cell antigen-like domains 2
chrX_-_48578878 0.471 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr10_+_21863099 0.468 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr19_+_14405100 0.468 NM_002741
PKN1
protein kinase N1
chr5_-_111121150 0.467 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr7_+_150390566 0.464 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr11_-_404975 0.463 NM_001135054
SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr2_+_46779553 0.461 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr5_-_77626222 0.461 AP3B1
adaptor-related protein complex 3, beta 1 subunit
chr12_+_26239535 0.455 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr17_-_74432800 0.453 TIMP2
TIMP metallopeptidase inhibitor 2
chr19_+_40321584 0.452 FXYD1
FXYD domain containing ion transport regulator 1
chr19_+_40321567 0.452 NM_021902
FXYD1
FXYD domain containing ion transport regulator 1
chr2_-_158440587 0.449 NM_001111067
ACVR1
activin A receptor, type I
chr17_-_7023378 0.447 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr2_-_158439868 0.445 NM_001105
ACVR1
activin A receptor, type I
chr7_+_73506333 0.445 NM_005685
GTF2IRD1
GTF2I repeat domain containing 1
chr1_-_201422450 0.443 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr16_+_166678 0.443 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr21_-_43671355 0.442 NM_173354
SIK1
salt-inducible kinase 1
chr14_-_103058865 0.440 NM_001823
CKB
creatine kinase, brain
chr4_-_5941167 0.440 NM_001313
CRMP1
collapsin response mediator protein 1
chr1_-_149213826 0.437 LASS2
LAG1 homolog, ceramide synthase 2
chr1_-_149213778 0.434 LASS2
LAG1 homolog, ceramide synthase 2
chr7_-_148212312 0.433 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_-_23977330 0.433 LOC100506963
hypothetical LOC100506963
chr15_+_41597097 0.430 NM_002373
MAP1A
microtubule-associated protein 1A
chr20_+_34143983 0.429 EPB41L1
erythrocyte membrane protein band 4.1-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 1.57e-05 GO:0051252 regulation of RNA metabolic process
1.71 2.28e-05 GO:0016568 chromatin modification
1.42 2.28e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.33 4.79e-05 GO:0007399 nervous system development
1.41 1.58e-04 GO:0048468 cell development
1.26 2.73e-04 GO:0006355 regulation of transcription, DNA-dependent
1.40 4.29e-04 GO:0022008 neurogenesis
1.46 4.42e-04 GO:0030182 neuron differentiation
1.22 6.91e-04 GO:0010468 regulation of gene expression
1.40 7.35e-04 GO:0048699 generation of neurons
1.19 9.25e-04 GO:0060255 regulation of macromolecule metabolic process
1.21 1.15e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.21 1.18e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 1.70e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.49 1.87e-03 GO:0051253 negative regulation of RNA metabolic process
1.21 1.97e-03 GO:0009889 regulation of biosynthetic process
1.21 1.99e-03 GO:0031326 regulation of cellular biosynthetic process
1.49 2.57e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.23 3.30e-03 GO:0048869 cellular developmental process
1.21 3.91e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.24 3.97e-03 GO:0030154 cell differentiation
1.42 4.68e-03 GO:0045595 regulation of cell differentiation
1.56 4.72e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.17 5.06e-03 GO:0080090 regulation of primary metabolic process
1.17 5.38e-03 GO:0031323 regulation of cellular metabolic process
1.45 6.24e-03 GO:0010629 negative regulation of gene expression
1.17 7.38e-03 GO:0048856 anatomical structure development
1.16 1.00e-02 GO:0007275 multicellular organismal development
1.40 1.05e-02 GO:0009890 negative regulation of biosynthetic process
1.40 1.14e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.41 1.33e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.15 1.44e-02 GO:0032502 developmental process
1.15 1.47e-02 GO:0019222 regulation of metabolic process
1.42 1.55e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.17 2.39e-02 GO:0048731 system development
1.59 2.55e-02 GO:0060284 regulation of cell development
1.39 2.70e-02 GO:0051254 positive regulation of RNA metabolic process
1.44 3.66e-02 GO:0000904 cell morphogenesis involved in differentiation
1.25 4.48e-02 GO:0009653 anatomical structure morphogenesis
1.40 4.70e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 1.34e-04 GO:0005634 nucleus
1.40 7.76e-04 GO:0044451 nucleoplasm part
1.21 1.61e-03 GO:0044428 nuclear part
1.21 9.54e-03 GO:0031981 nuclear lumen
4.10 1.04e-02 GO:0042627 chylomicron
1.05 4.16e-02 GO:0044424 intracellular part
1.04 4.89e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 8.39e-05 GO:0005515 protein binding
1.31 7.58e-03 GO:0030528 transcription regulator activity
1.38 9.39e-03 GO:0043565 sequence-specific DNA binding