Motif ID: PAX2.p2

Z-value: 1.084


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX2chr10_+_1024953270.263.3e-01Click!


Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_61615124 1.705 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_+_100270222 1.621 DLK1
delta-like 1 homolog (Drosophila)
chr6_+_160310118 1.618 NM_000876
 IGF2R
insulin-like growth factor 2 receptor
chr12_-_61614930 1.480 NM_020700
 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_-_39556535 1.298 NM_001015053
NM_005474
 HDAC5

histone deacetylase 5

chr17_-_39556483 1.228 HDAC5
histone deacetylase 5
chr17_+_77529070 1.219 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr14_+_23653848 1.058 DCAF11
DDB1 and CUL4 associated factor 11
chrX_+_30581377 1.017 NM_000167
NM_001128127
NM_203391
 GK


glycerol kinase


chr18_+_9126742 0.942 NM_001083625
NM_015208
 ANKRD12

ankyrin repeat domain 12

chr14_+_23654161 0.924 DCAF11
DDB1 and CUL4 associated factor 11
chr2_+_74914742 0.900 HK2
hexokinase 2
chr17_+_75689894 0.897 NM_000152
NM_001079803
NM_001079804
 GAA


glucosidase, alpha; acid


chr1_-_152459667 0.890 C1orf43
chromosome 1 open reading frame 43
chr14_+_23653819 0.881 NM_025230
 DCAF11
DDB1 and CUL4 associated factor 11
chr6_-_90178685 0.859 NM_021244
 RRAGD
Ras-related GTP binding D
chr11_+_7574992 0.835 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_+_69314347 0.833 NM_012238
 SIRT1
sirtuin 1
chr14_+_23653745 0.831 NM_001163484
 DCAF11
DDB1 and CUL4 associated factor 11
chr6_+_87921980 0.826 NM_015021
 ZNF292
zinc finger protein 292

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.33 2.81e-05 GO:0010467 gene expression
1.33 1.76e-04 GO:0016070 RNA metabolic process
1.31 8.26e-06 GO:0090304 nucleic acid metabolic process
1.31 1.25e-03 GO:0009059 macromolecule biosynthetic process
1.30 1.78e-03 GO:0034645 cellular macromolecule biosynthetic process
1.26 5.58e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.23 4.97e-03 GO:0044249 cellular biosynthetic process
1.22 6.58e-04 GO:0034641 cellular nitrogen compound metabolic process
1.22 9.22e-03 GO:0009058 biosynthetic process
1.21 4.94e-04 GO:0006807 nitrogen compound metabolic process
1.16 3.50e-03 GO:0044260 cellular macromolecule metabolic process
1.15 7.98e-03 GO:0043170 macromolecule metabolic process
1.13 3.79e-03 GO:0044237 cellular metabolic process
1.11 1.85e-02 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
1.40 2.76e-06 GO:0005654 nucleoplasm
1.29 3.00e-06 GO:0031974 membrane-enclosed lumen
1.29 4.32e-06 GO:0043233 organelle lumen
1.28 1.12e-05 GO:0070013 intracellular organelle lumen
1.28 3.64e-04 GO:0031981 nuclear lumen
1.25 7.48e-04 GO:0044428 nuclear part
1.19 3.15e-08 GO:0005634 nucleus
1.14 6.30e-04 GO:0044422 organelle part
1.14 1.06e-03 GO:0044446 intracellular organelle part
1.13 3.48e-09 GO:0043231 intracellular membrane-bounded organelle
1.13 4.00e-09 GO:0043227 membrane-bounded organelle
1.11 6.46e-08 GO:0043226 organelle
1.11 7.64e-08 GO:0043229 intracellular organelle
1.09 1.91e-08 GO:0044424 intracellular part
1.09 2.42e-08 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.59 4.29e-03 GO:0003712 transcription cofactor activity
1.59 4.86e-03 GO:0000988 protein binding transcription factor activity
1.59 4.86e-03 GO:0000989 transcription factor binding transcription factor activity
1.39 8.24e-03 GO:0003723 RNA binding
1.33 4.82e-02 GO:0001071 nucleic acid binding transcription factor activity
1.33 4.82e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.28 1.41e-04 GO:0003677 DNA binding
1.27 3.18e-07 GO:0003676 nucleic acid binding
1.10 6.87e-03 GO:0005515 protein binding
1.05 2.25e-02 GO:0005488 binding