Motif ID: ZIC1..3.p2

Z-value: 0.763


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZIC1chr3_+_1486098410.514.4e-02Click!
ZIC3chrX_+_136475979-0.431.0e-01Click!


Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_52812165 1.634 FST
follistatin
chr15_+_37660568 1.590 NM_003246
 THBS1
thrombospondin 1
chr16_+_69060325 1.249 FUK
fucokinase
chr5_-_121440704 1.193 NM_001178102
 LOX
lysyl oxidase
chr11_-_11987115 1.189 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr11_-_111287657 1.184 NM_001885
 CRYAB
crystallin, alpha B
chr5_+_52812236 1.174 NM_006350
NM_013409
 FST

follistatin

chr10_-_90702490 1.118 NM_001613
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_-_65396775 1.091 NM_016938
 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr21_+_41461962 1.078 BACE2
beta-site APP-cleaving enzyme 2
chr11_-_11986704 0.993 NM_001018057
 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr11_+_19691397 0.985 NM_145117
NM_182964
 NAV2

neuron navigator 2

chr16_+_31390567 0.975 NM_001042454
NM_001164719
 TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr15_+_61127367 0.974 NM_001018008
 TPM1
tropomyosin 1 (alpha)
chr11_-_11987198 0.974 NM_015881
 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr10_+_75343352 0.955 PLAU
plasminogen activator, urokinase
chr3_-_73756668 0.948 NM_015009
 PDZRN3
PDZ domain containing ring finger 3
chr11_+_111288669 0.938 NM_001541
 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr11_-_2108035 0.917 IGF2
insulin-like growth factor 2 (somatomedin A)
chrX_-_128485134 0.884 NM_003069
NM_139035
 SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.35 3.86e-03 GO:0034330 cell junction organization
2.35 1.12e-02 GO:0034329 cell junction assembly
2.23 4.73e-02 GO:0042692 muscle cell differentiation
1.86 2.82e-02 GO:0061061 muscle structure development
1.71 7.13e-03 GO:0061024 membrane organization
1.69 1.26e-02 GO:0016044 cellular membrane organization
1.54 7.83e-03 GO:0016192 vesicle-mediated transport
1.49 4.34e-06 GO:0009653 anatomical structure morphogenesis
1.48 9.92e-03 GO:0048468 cell development
1.40 1.07e-05 GO:0048869 cellular developmental process
1.40 1.18e-05 GO:0030154 cell differentiation
1.32 1.57e-06 GO:0048856 anatomical structure development
1.32 1.28e-05 GO:0048731 system development
1.28 2.02e-06 GO:0032502 developmental process
1.27 1.03e-04 GO:0007275 multicellular organismal development
1.20 3.04e-04 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
2.50 3.12e-03 GO:0005925 focal adhesion
2.42 8.97e-05 GO:0005912 adherens junction
2.39 7.37e-03 GO:0005924 cell-substrate adherens junction
2.35 7.00e-05 GO:0070161 anchoring junction
2.29 1.63e-02 GO:0030055 cell-substrate junction
2.09 2.85e-02 GO:0030136 clathrin-coated vesicle
2.06 4.33e-03 GO:0005911 cell-cell junction
1.99 1.65e-02 GO:0030135 coated vesicle
1.96 2.53e-02 GO:0031252 cell leading edge
1.89 8.34e-03 GO:0016323 basolateral plasma membrane
1.81 2.28e-06 GO:0030054 cell junction
1.77 1.11e-02 GO:0015629 actin cytoskeleton
1.62 4.99e-05 GO:0016023 cytoplasmic membrane-bounded vesicle
1.60 6.47e-05 GO:0031410 cytoplasmic vesicle
1.59 1.58e-04 GO:0031988 membrane-bounded vesicle
1.54 4.74e-04 GO:0031982 vesicle
1.27 4.68e-03 GO:0044459 plasma membrane part
1.26 8.97e-06 GO:0005886 plasma membrane
1.25 7.55e-06 GO:0071944 cell periphery
1.16 5.68e-05 GO:0016020 membrane

Nothing significant found in function category.