Motif ID: HSF1,2.p2

Z-value: 1.717


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
HSF1 3297 heat shock transcription factor 1
HSF2 3298 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HSF2chr6_+_122762384-0.476.8e-02Click!
HSF1chr8_+_145486052,
chr8_+_145486087		-0.078.1e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_224611568 5.721 NM_001136530
 SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr6_+_151688327 4.238 NM_144497
 AKAP12
A kinase (PRKA) anchor protein 12
chrX_+_135058402 4.218 NM_001159700
 FHL1
four and a half LIM domains 1
chr7_+_134114957 4.146 CALD1
caldesmon 1
chr7_+_134114701 3.700 NM_004342
NM_033138
NM_033157
 CALD1


caldesmon 1


chr16_+_69060325 3.643 FUK
fucokinase
chr14_-_51605487 3.571 NID2
nidogen 2 (osteonidogen)
chr14_-_51605695 3.452 NM_007361
 NID2
nidogen 2 (osteonidogen)
chr20_+_19818209 3.426 NM_018993
 RIN2
Ras and Rab interactor 2
chr2_-_105421661 3.247 NM_201557
 FHL2
four and a half LIM domains 2
chr8_-_13018123 3.229 NM_001164271
 DLC1
deleted in liver cancer 1
chr14_-_51605515 3.125 NID2
nidogen 2 (osteonidogen)
chr14_-_51605461 3.040 NID2
nidogen 2 (osteonidogen)
chr2_-_188127430 3.025 NM_001032281
NM_006287
 TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr3_+_160269734 2.959 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
 IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr11_-_118799452 2.907 NM_006288
 THY1
Thy-1 cell surface antigen
chr12_+_118100977 2.860 NM_014365
 HSPB8
heat shock 22kDa protein 8
chr2_-_188127294 2.478 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr6_+_146906520 2.262 NM_006834
 RAB32
RAB32, member RAS oncogene family
chr2_-_189752575 2.260 NM_000393
 COL5A2
collagen, type V, alpha 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
9.53 4.22e-05 GO:0060678 dichotomous subdivision of terminal units involved in ureteric bud branching
8.47 3.44e-04 GO:0048880 sensory system development
8.47 3.44e-04 GO:0048892 lateral line nerve development
8.47 3.44e-04 GO:0048895 lateral line nerve glial cell differentiation
8.47 3.44e-04 GO:0048925 lateral line system development
8.47 3.44e-04 GO:0048937 lateral line nerve glial cell development
8.47 3.44e-04 GO:0050935 iridophore differentiation
7.80 1.99e-04 GO:0060600 dichotomous subdivision of an epithelial terminal unit
6.93 5.19e-03 GO:0090184 positive regulation of kidney development
6.81 3.10e-04 GO:0048484 enteric nervous system development
6.35 8.42e-04 GO:0030513 positive regulation of BMP signaling pathway
6.35 1.41e-02 GO:0048846 axon extension involved in axon guidance
3.75 3.97e-02 GO:0014033 neural crest cell differentiation
2.96 4.70e-02 GO:0014031 mesenchymal cell development
2.92 3.37e-02 GO:0048762 mesenchymal cell differentiation
1.86 8.95e-06 GO:0006928 cellular component movement
1.78 2.51e-06 GO:0007155 cell adhesion
1.78 2.51e-06 GO:0022610 biological adhesion
1.73 1.18e-02 GO:0048870 cell motility
1.73 1.18e-02 GO:0051674 localization of cell

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.47 3.09e-02 GO:0005581 collagen
2.63 7.74e-04 GO:0044420 extracellular matrix part
1.96 8.06e-05 GO:0031012 extracellular matrix
1.95 1.22e-03 GO:0005578 proteinaceous extracellular matrix
1.65 1.67e-07 GO:0044421 extracellular region part
1.61 8.04e-05 GO:0005615 extracellular space
1.45 1.56e-06 GO:0005576 extracellular region

Nothing significant found in function category.