Motif ID: POU3F1..4.p2

Z-value: 1.159


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU3F2chr6_+_993893000.647.9e-03Click!
POU3F4chrX_+_82649924-0.401.2e-01Click!
POU3F3chr2_+_1048381770.361.7e-01Click!
POU3F1chr1_-_38285033-0.019.7e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_90029328 3.914 LUM
lumican
chr2_+_189547358 3.376 COL3A1
collagen, type III, alpha 1
chr17_-_44037332 3.310 NM_018952
HOXB6
homeobox B6
chr12_-_90100733 3.283 NM_001920
DCN
decorin
chrX_+_65300803 3.262 NM_001130860
NM_014799
HEPH

hephaestin

chr2_+_189547377 3.245 COL3A1
collagen, type III, alpha 1
chr2_+_189547323 2.528 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_151922350 2.520 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_-_162808123 2.129 NM_004460
FAP
fibroblast activation protein, alpha
chrX_+_100692071 2.092 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr15_-_53996597 1.923 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr9_+_74956601 1.870 ANXA1
annexin A1
chrX_-_135577102 1.849 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr8_-_13018123 1.730 NM_001164271
DLC1
deleted in liver cancer 1
chr9_+_74956614 1.706 ANXA1
annexin A1
chr9_+_74956494 1.685 NM_000700
ANXA1
annexin A1
chr20_+_9406460 1.562 PLCB4
phospholipase C, beta 4
chr13_-_37070862 1.461 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr5_+_34720368 1.460 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr6_+_121798443 1.415 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr4_+_169654742 1.359 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr1_-_171441234 1.307 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chrX_+_65299157 1.268 NM_138737
HEPH
hephaestin
chr13_+_100902942 1.206 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chrX_-_137649180 1.187 NM_033642
FGF13
fibroblast growth factor 13
chr1_+_78243181 1.183 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr6_-_169395972 1.180 NM_003247
THBS2
thrombospondin 2
chr3_-_124821868 1.104 MYLK
myosin light chain kinase
chr1_-_143786993 1.089 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr3_-_170348215 1.065 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr1_+_169326641 1.024 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr15_-_75135496 1.008 TSPAN3
tetraspanin 3
chr10_-_75080784 0.985 NM_024875
SYNPO2L
synaptopodin 2-like
chr12_-_7136189 0.984 C1R
complement component 1, r subcomponent
chr2_-_190635566 0.973 NM_005259
MSTN
myostatin
chr7_-_124192916 0.882 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr17_-_1211263 0.866 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr6_-_138862273 0.864


chr11_-_85146691 0.820 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr3_+_70068440 0.810 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr1_-_143708467 0.790 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr12_-_7136147 0.773 NM_001733
C1R
complement component 1, r subcomponent
chr15_-_21483503 0.764 NM_002487
NDN
necdin homolog (mouse)
chr6_-_46997579 0.738 NM_001098518
GPR116
G protein-coupled receptor 116
chr21_+_29374743 0.709 NM_020152
C21orf7
chromosome 21 open reading frame 7
chr11_+_71580816 0.708 NM_016729
FOLR1
folate receptor 1 (adult)
chr9_+_137107007 0.699 OLFM1
olfactomedin 1
chr2_+_108604111 0.695 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chrX_-_10495476 0.681 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chrX_+_47999740 0.680 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr7_-_136678901 0.678 PTN
pleiotrophin
chr8_-_93099040 0.676 NM_175636
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_101077605 0.667 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr6_-_46401363 0.627 NM_005822
RCAN2
regulator of calcineurin 2
chrX_+_106758395 0.625 PRPS1
phosphoribosyl pyrophosphate synthetase 1
chr4_-_100461530 0.625 NM_000668
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chr5_+_141326620 0.614 NM_183399
RNF14
ring finger protein 14
chr3_-_124822113 0.612 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr12_-_9913199 0.593 CLEC2B
C-type lectin domain family 2, member B
chr17_+_29606408 0.582 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr7_+_129913271 0.558 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chrX_+_99785818 0.544 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr7_-_50740491 0.541 NM_001001550
GRB10
growth factor receptor-bound protein 10
chrX_+_106758309 0.534 NM_002764
PRPS1
phosphoribosyl pyrophosphate synthetase 1
chr12_+_52708460 0.532 NM_004503
HOXC6
homeobox C6
chr7_-_136678973 0.524 PTN
pleiotrophin
chr2_+_108590032 0.512 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_-_153209625 0.510 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr5_+_140709907 0.506 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr17_+_4795128 0.504 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr7_+_102775309 0.500 NM_002803
PSMC2
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr12_-_9913724 0.495 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr16_+_6763810 0.493 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_-_110735158 0.489 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr3_+_11242666 0.485 NM_001098211
HRH1
histamine receptor H1
chr1_+_201711578 0.478 PRELP
proline/arginine-rich end leucine-rich repeat protein
chr9_+_137107187 0.461 OLFM1
olfactomedin 1
chr2_-_206790871 0.459 NM_001098199
NM_005279
GPR1

G protein-coupled receptor 1

chr5_+_43645018 0.447 NNT
nicotinamide nucleotide transhydrogenase
chr8_-_93181091 0.446 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_-_77730573 0.444 NM_012296
GAB2
GRB2-associated binding protein 2
chr13_-_21076275 0.442 EFHA1
EF-hand domain family, member A1
chr11_-_5212168 0.440 NM_000519
HBD
hemoglobin, delta
chr13_-_35327798 0.438 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr2_-_217268492 0.435 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr1_-_89364273 0.433 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr1_-_143706196 0.421 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_143706300 0.414 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr6_+_46869052 0.410 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr18_-_51219880 0.401 TCF4
transcription factor 4
chr8_-_18710575 0.394 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr7_+_12217343 0.392 NM_001134232
NM_018374
TMEM106B

transmembrane protein 106B

chr2_-_231697999 0.389 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr7_-_136678815 0.386 PTN
pleiotrophin
chr8_+_1980564 0.377 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr1_+_195179533 0.365 NM_005666
CFHR2
complement factor H-related 2
chr2_-_110665188 0.365 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr7_-_136679045 0.361 NM_002825
PTN
pleiotrophin
chr12_-_103846186 0.355 NM_032148
SLC41A2
solute carrier family 41, member 2
chr5_+_140790365 0.351 PCDHGA12
protocadherin gamma subfamily A, 12
chr3_+_185377341 0.350 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_-_21250039 0.344 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr9_+_137107222 0.339 OLFM1
olfactomedin 1
chr5_+_34723420 0.332 NM_001145523
RAI14
retinoic acid induced 14
chrX_+_54850832 0.327 NM_177433
MAGED2
melanoma antigen family D, 2
chr5_-_156935317 0.325 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr1_-_108536885 0.320 NM_213651
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr2_-_144994038 0.314 ZEB2
zinc finger E-box binding homeobox 2
chr8_-_11739592 0.311 CTSB
cathepsin B
chr5_+_140790310 0.305 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr22_-_35494019 0.294 NM_001177702
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr12_-_8110268 0.282 C3AR1
complement component 3a receptor 1
chr1_+_51208499 0.281 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr7_-_87694218 0.273 NM_198901
SRI
sorcin
chr16_+_31027231 0.267 BCKDK
branched chain ketoacid dehydrogenase kinase
chr2_+_108571209 0.262 LIMS1
LIM and senescent cell antigen-like domains 1
chr1_-_21249974 0.262 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_+_176577228 0.256 NM_004841
RASAL2
RAS protein activator like 2
chr5_+_64956586 0.253 C5orf44
chromosome 5 open reading frame 44
chr2_+_183290912 0.253 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr8_-_62764839 0.251 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr18_+_41560915 0.248 NM_001146037
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chr1_-_143706265 0.247 PDE4DIP
phosphodiesterase 4D interacting protein
chrX_+_102770547 0.246 NM_001006639
NM_004780
TCEAL1

transcription elongation factor A (SII)-like 1

chr15_+_68971835 0.244 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr8_-_102029997 0.241 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr14_-_99911679 0.234 NM_004184
NM_213646
WARS

tryptophanyl-tRNA synthetase

chr8_+_49083522 0.232 NM_003350
UBE2V2
ubiquitin-conjugating enzyme E2 variant 2
chr4_+_154345039 0.231 NM_015271
TRIM2
tripartite motif containing 2
chr5_+_140723939 0.230 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr16_+_72888231 0.230 PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr12_-_10215942 0.229 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr2_-_37397669 0.228 NM_005813
PRKD3
protein kinase D3
chr17_+_58440629 0.227 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr6_+_28342766 0.227 NM_001023560
NM_001111039
NM_152736
ZNF187


zinc finger protein 187


chr10_-_73953699 0.227 NM_001195519
CBARA1
calcium binding atopy-related autoantigen 1
chr3_+_189425886 0.225 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr13_+_47776026 0.223 RB1
retinoblastoma 1
chr10_+_124310170 0.222 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr1_-_240228987 0.222 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr17_-_64462976 0.222 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr4_-_145281237 0.214 NM_002099
GYPA
glycophorin A (MNS blood group)
chr9_+_91409746 0.214 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr9_-_110815542 0.213 NM_003798
CTNNAL1
catenin (cadherin-associated protein), alpha-like 1
chr20_+_11819364 0.211 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr17_-_8364942 0.210 MYH10
myosin, heavy chain 10, non-muscle
chrX_-_109570113 0.209 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr17_+_54997667 0.208 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr14_+_100365390 0.208 MEG3
maternally expressed 3 (non-protein coding)
chr1_+_196392513 0.207 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr12_-_8110196 0.206 NM_004054
C3AR1
complement component 3a receptor 1
chrM_-_8294 0.206 FTH1
ferritin, heavy polypeptide 1
chr16_+_72888161 0.205 NM_002811
PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr6_-_76027286 0.205 TMEM30A
transmembrane protein 30A
chr2_+_24660849 0.202 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr6_+_43507466 0.198 NM_033450
ABCC10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr9_+_134843918 0.196 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr2_+_188864848 0.193 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr3_+_33293915 0.193 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr12_+_50342814 0.192 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr2_-_161058120 0.192 RBMS1
RNA binding motif, single stranded interacting protein 1
chr11_-_130291584 0.191 NM_014758
SNX19
sorting nexin 19
chr21_-_34909014 0.191 NM_004414
RCAN1
regulator of calcineurin 1
chr6_+_132000134 0.189 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr10_-_69095362 0.189 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr5_+_52892217 0.185 NM_002495
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr12_-_109842736 0.184 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr8_+_17478214 0.183 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr16_+_31027249 0.183 BCKDK
branched chain ketoacid dehydrogenase kinase
chr15_+_46957556 0.182 NM_014335
EID1
EP300 interacting inhibitor of differentiation 1
chr12_-_69317441 0.180 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr14_+_95792299 0.179 NM_000710
BDKRB1
bradykinin receptor B1
chr2_+_108571177 0.179 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr11_-_130291527 0.177 SNX19
sorting nexin 19
chr14_-_73250094 0.176 NM_006029
PNMA1
paraneoplastic antigen MA1
chr3_-_115825742 0.175 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr7_+_80113570 0.173 NM_001127443
NM_001127444
CD36

CD36 molecule (thrombospondin receptor)

chr1_-_77457664 0.172 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr5_+_40945315 0.170 NM_000587
C7
complement component 7
chr15_-_86890796 0.170 NM_001144074
NM_017996
DET1

de-etiolated homolog 1 (Arabidopsis)

chr1_+_201711505 0.169 NM_002725
NM_201348
PRELP

proline/arginine-rich end leucine-rich repeat protein

chr2_+_223625105 0.167 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr13_-_77390907 0.166 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr4_+_25931725 0.163 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chrX_-_15530112 0.162 NM_021804
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr2_-_3583801 0.161 NM_002936
RNASEH1
ribonuclease H1
chrX_+_77052834 0.160 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr7_+_100111712 0.158 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr5_+_140751666 0.156 NM_014004
NM_032088
PCDHGA8

protocadherin gamma subfamily A, 8

chr17_+_7753428 0.156 CHD3
chromodomain helicase DNA binding protein 3
chr4_-_77176163 0.155 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr5_+_40945374 0.153 C7
complement component 7
chr7_-_139948780 0.146 NM_015689
DENND2A
DENN/MADD domain containing 2A
chr2_-_47969350 0.146 NM_025133
FBXO11
F-box protein 11
chr19_-_4351357 0.145 SH3GL1
SH3-domain GRB2-like 1
chr7_-_76667045 0.144 NM_006682
FGL2
fibrinogen-like 2
chr7_+_23252802 0.144 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr12_-_9123126 0.143 A2M
alpha-2-macroglobulin
chr1_+_195123766 0.143 NM_006684
CFHR4
complement factor H-related 4
chr11_+_102485293 0.142 NM_001080463
NM_001377
DYNC2H1

dynein, cytoplasmic 2, heavy chain 1


Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.36 6.93e-03 GO:0071944 cell periphery
1.34 1.89e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.21 1.91e-02 GO:0008081 phosphoric diester hydrolase activity