Motif ID: PAX4.p2

Z-value: 1.516


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX4chr7_-_127042810-0.439.3e-02Click!


Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_113671744 3.613 NM_006169
NNMT
nicotinamide N-methyltransferase
chr1_-_30977931 3.403 LAPTM5
lysosomal protein transmembrane 5
chr18_-_51406841 2.846 NM_001083962
NM_003199
TCF4

transcription factor 4

chr1_+_149298774 2.311 NM_006818
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_101474892 2.287 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr6_-_31805932 2.132 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_+_149299530 2.104 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_149299307 2.094 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr6_-_31806012 2.085 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_+_149299504 2.071 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr1_+_149299490 2.040 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr18_-_51406359 1.999 TCF4
transcription factor 4
chr18_+_71051713 1.957 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr1_+_101475149 1.760 S1PR1
sphingosine-1-phosphate receptor 1
chr20_-_23010786 1.755 CD93
CD93 molecule
chrY_+_2769630 1.720 RPS4Y1
ribosomal protein S4, Y-linked 1
chr2_-_237987509 1.466 COL6A3
collagen, type VI, alpha 3
chr1_+_144236346 1.465 NM_003637
ITGA10
integrin, alpha 10
chr7_+_93388951 1.320 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr2_-_237987579 1.307 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chrX_+_65300803 1.236 NM_001130860
NM_014799
HEPH

hephaestin

chr11_-_77730573 1.180 NM_012296
GAB2
GRB2-associated binding protein 2
chr12_+_74160779 1.155 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr4_+_40953698 1.127 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr8_-_13178399 1.102 DLC1
deleted in liver cancer 1
chr6_-_90119329 1.084 NM_016021
UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr2_-_237987554 1.047 COL6A3
collagen, type VI, alpha 3
chr15_+_61127367 1.006 NM_001018008
TPM1
tropomyosin 1 (alpha)
chr4_+_40953666 0.978 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr19_+_14405216 0.971 PKN1
protein kinase N1
chr22_-_16060485 0.957 NM_177405
CECR1
cat eye syndrome chromosome region, candidate 1
chr2_-_217268492 0.944 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr4_+_87070449 0.920 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chrY_+_2769596 0.911 NM_001008
RPS4Y1
ribosomal protein S4, Y-linked 1
chr8_-_82557956 0.910 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr17_+_4795128 0.909 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr11_+_1830763 0.875 NM_002339
LSP1
lymphocyte-specific protein 1
chr6_-_90119169 0.874 UBE2J1
ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)
chr13_+_109936080 0.872 COL4A2
collagen, type IV, alpha 2
chr4_-_187114863 0.846 NM_021069
SORBS2
sorbin and SH3 domain containing 2
chr15_+_61122139 0.842 TPM1
tropomyosin 1 (alpha)
chr17_-_15104768 0.796 NM_153322
PMP22
peripheral myelin protein 22
chr2_-_136590210 0.787 NM_001008540
CXCR4
chemokine (C-X-C motif) receptor 4
chr17_-_44037332 0.756 NM_018952
HOXB6
homeobox B6
chrX_+_99785818 0.748 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr7_-_50740491 0.742 NM_001001550
GRB10
growth factor receptor-bound protein 10
chr19_-_50688310 0.739 NM_206901
RTN2
reticulon 2
chr15_-_75135496 0.737 TSPAN3
tetraspanin 3
chr4_+_40953652 0.708 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr12_+_54832470 0.701 NM_002475
MYL6B
myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr5_-_95184121 0.700 GLRX
glutaredoxin (thioltransferase)
chr12_+_32003648 0.689 C12orf35
chromosome 12 open reading frame 35
chr12_+_32003553 0.656 NM_018169
C12orf35
chromosome 12 open reading frame 35
chrX_+_99786044 0.651 SRPX2
sushi-repeat containing protein, X-linked 2
chr5_-_95184221 0.649 NM_001118890
NM_002064
GLRX

glutaredoxin (thioltransferase)

chr12_-_122283598 0.646 MPHOSPH9
M-phase phosphoprotein 9
chr1_-_42738535 0.640 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr5_-_126394338 0.635 NM_178450
MARCH3
membrane-associated ring finger (C3HC4) 3
chr2_+_223625105 0.613 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr3_+_69216747 0.603 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chrY_+_2619224 0.593 NM_001122898
NM_002414
CD99

CD99 molecule

chrX_+_2619224 0.593 NM_001122898
NM_002414
CD99

CD99 molecule

chr1_-_148936123 0.588 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr14_-_99912340 0.554 WARS
tryptophanyl-tRNA synthetase
chr12_+_10256682 0.544 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr6_+_57145017 0.543 NM_004282
BAG2
BCL2-associated athanogene 2
chr7_+_80105858 0.537 CD36
CD36 molecule (thrombospondin receptor)
chr19_+_14405100 0.534 NM_002741
PKN1
protein kinase N1
chr11_+_20341806 0.532 NM_006410
NM_001098521
HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr9_+_27099138 0.528 NM_000459
TEK
TEK tyrosine kinase, endothelial
chr2_+_170259195 0.524 NM_144711
NM_001008489
PHOSPHO2-KLHL23
KLHL23
PHOSPHO2
PHOSPHO2-KLHL23 read-through transcript
kelch-like 23 (Drosophila)
phosphatase, orphan 2
chr11_-_61341011 0.518 NM_013402
FADS1
fatty acid desaturase 1
chr12_+_54400417 0.516 NM_002905
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr15_-_46725087 0.516 NM_000138
FBN1
fibrillin 1
chr20_+_42644633 0.513 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr1_-_89364273 0.512 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr8_-_145624690 0.503 VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chrX_+_102498035 0.497 NM_001006612
NM_001006613
NM_001006614
NM_016303
WBP5



WW domain binding protein 5



chr8_-_145624719 0.488 NM_016208
NM_183057
VPS28

vacuolar protein sorting 28 homolog (S. cerevisiae)

chr11_-_62231242 0.483 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_+_115448592 0.472 NM_016144
COMMD10
COMM domain containing 10
chr2_-_217267742 0.470 IGFBP5
insulin-like growth factor binding protein 5
chr11_-_62231445 0.470 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr2_+_217206450 0.468 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr11_+_20341900 0.461 NM_001098522
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr8_-_145624708 0.460 VPS28
vacuolar protein sorting 28 homolog (S. cerevisiae)
chr16_+_15435825 0.457 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr3_+_139549228 0.453 NM_012219
MRAS
muscle RAS oncogene homolog
chr8_+_75066117 0.452 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr11_-_62231358 0.450 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr4_-_88531353 0.440 NM_016245
HSD17B11
hydroxysteroid (17-beta) dehydrogenase 11
chr11_+_124967961 0.435 STT3A
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr4_-_76658606 0.433 NM_001008925
NM_001009922
NM_015436
RCHY1


ring finger and CHY zinc finger domain containing 1


chr11_-_62231386 0.429 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr14_-_99912390 0.422 WARS
tryptophanyl-tRNA synthetase
chr14_+_100370559 0.420 MEG3
maternally expressed 3 (non-protein coding)
chr1_-_1613802 0.418 SLC35E2B
SLC35E2
solute carrier family 35, member E2B
solute carrier family 35, member E2
chr7_-_50767512 0.417 NM_001001549
NM_005311
GRB10

growth factor receptor-bound protein 10

chr1_+_170656450 0.412 NM_139240
C1orf105
chromosome 1 open reading frame 105
chr1_+_12046020 0.411 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr8_+_41467283 0.408 NM_001002296
GOLGA7
golgin A7
chr14_-_99912429 0.407 NM_173701
NM_213645
WARS

tryptophanyl-tRNA synthetase

chr4_-_115120251 0.407 NM_024590
ARSJ
arylsulfatase family, member J
chrX_+_52255534 0.404 NM_001097597
NM_001097598
NM_001097604
NM_001097605
NM_001097592
NM_001097593
NM_001097594
NM_001097596
NM_020411
NM_133430
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr4_-_186815116 0.403 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr8_+_41467251 0.400 GOLGA7
golgin A7
chr10_-_69762654 0.399 NM_001033083
NM_022129
PBLD

phenazine biosynthesis-like protein domain containing

chr4_+_26194643 0.397 NM_018317
TBC1D19
TBC1 domain family, member 19
chr2_-_151052391 0.396 NM_005168
RND3
Rho family GTPase 3
chr19_+_54707347 0.393 NM_001136019
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr7_+_80105907 0.392 CD36
CD36 molecule (thrombospondin receptor)
chr7_+_115926679 0.392 NM_001233
NM_198212
CAV2

caveolin 2

chr2_+_217206327 0.392 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr2_-_20886293 0.391 NM_021925
C2orf43
chromosome 2 open reading frame 43
chr19_+_17239264 0.391 BABAM1
BRISC and BRCA1 A complex member 1
chr10_-_49483002 0.388 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr8_+_41467262 0.385 GOLGA7
golgin A7
chr4_-_170915602 0.379 NM_017867
C4orf27
chromosome 4 open reading frame 27
chr21_-_45118037 0.375 NM_004339
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr20_+_36508690 0.368 SNHG11
small nucleolar RNA host gene 11 (non-protein coding)
chrX_+_52528485 0.368 NM_001097597
NM_001097598
NM_001097604
NM_001097605
NM_001097592
NM_001097593
NM_001097594
NM_001097596
NM_020411
NM_133430
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chrX_-_52276878 0.366 NM_001097598
NM_001097597
NM_001097605
NM_001097604
NM_001097593
NM_001097592
NM_001097596
NM_001097594
NM_133430
NM_020411
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr4_-_140280031 0.364 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chrX_-_52562712 0.355 NM_001097598
NM_001097597
NM_001097605
NM_001097604
NM_001097593
NM_001097592
NM_001097596
NM_001097594
NM_133430
NM_020411
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr11_-_62229477 0.351 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr5_-_121441805 0.350 LOX
lysyl oxidase
chr2_-_222145240 0.350 NM_004438
EPHA4
EPH receptor A4
chr8_+_41467241 0.349 GOLGA7
golgin A7
chr12_+_79634820 0.343 NM_005593
MYF5
myogenic factor 5
chr11_+_20341835 0.342 NM_001098520
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr7_-_149960218 0.331 GIMAP6
GTPase, IMAP family member 6
chrX_-_52549818 0.329 NM_001097598
NM_001097597
NM_001097605
NM_001097604
NM_001097593
NM_001097592
NM_001097596
NM_001097594
NM_133430
NM_020411
XAGE1C

XAGE1E

XAGE1A

XAGE1B

XAGE1D

X antigen family, member 1C

X antigen family, member 1E

X antigen family, member 1A

X antigen family, member 1B

X antigen family, member 1D

chr2_-_85692689 0.328 NM_001013649
C2orf68
chromosome 2 open reading frame 68
chr19_+_17239148 0.327 NM_001033549
NM_014173
BABAM1

BRISC and BRCA1 A complex member 1

chr5_-_121441910 0.326 NM_002317
LOX
lysyl oxidase
chr20_+_9236446 0.322 NM_000933
PLCB4
phospholipase C, beta 4
chr9_+_115303527 0.316 NM_130795
RGS3
regulator of G-protein signaling 3
chr1_-_31003181 0.314 LAPTM5
lysosomal protein transmembrane 5
chr4_-_121207338 0.314 NM_002358
MAD2L1
MAD2 mitotic arrest deficient-like 1 (yeast)
chrX_+_30143595 0.314 NM_002364
MAGEB2
melanoma antigen family B, 2
chr2_-_190892730 0.303 HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr8_+_41467220 0.303 NM_001174124
NM_016099
GOLGA7

golgin A7

chr1_-_148473649 0.302 NM_001136479
ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr3_+_9950513 0.302 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr5_-_93472993 0.301 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr13_+_75232797 0.300 NM_015842
LMO7
LIM domain 7
chr7_+_26158257 0.299 NM_004289
NFE2L3
nuclear factor (erythroid-derived 2)-like 3
chr21_+_39681558 0.298 NM_001146218
WRB
tryptophan rich basic protein
chr1_+_51208499 0.296 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr2_-_218551786 0.295 TNS1
tensin 1
chr2_+_47483795 0.295 MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr4_-_16509446 0.286 NM_001130834
NM_001290
LDB2

LIM domain binding 2

chr20_-_4743768 0.286 NM_170774
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr1_+_208067974 0.286 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr5_-_121441866 0.285 LOX
lysyl oxidase
chr2_+_73973600 0.285 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr1_-_1614040 0.284 NM_001110781
SLC35E2B
solute carrier family 35, member E2B
chr14_+_61298815 0.277 NM_003082
SNAPC1
small nuclear RNA activating complex, polypeptide 1, 43kDa
chr16_+_51646292 0.277 NM_025134
CHD9
chromodomain helicase DNA binding protein 9
chr11_-_65871592 0.276 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chrX_-_119593646 0.276 NM_003588
CUL4B
cullin 4B
chr9_+_91409746 0.270 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr9_-_134271985 0.269 NM_007344
TTF1
transcription termination factor, RNA polymerase I
chr5_+_147775652 0.266 FBXO38
F-box protein 38
chr5_+_162862808 0.264 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr2_-_88066423 0.263 NM_001024457
RGPD1
RANBP2-like and GRIP domain containing 1
chr6_+_34964999 0.262 NM_015245
ANKS1A
ankyrin repeat and sterile alpha motif domain containing 1A
chr4_+_78172966 0.259 SEPT11
septin 11
chr7_-_23476497 0.259 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr1_-_47468029 0.255 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr8_+_55533047 0.254 NM_022454
SOX17
SRY (sex determining region Y)-box 17
chr17_+_16225117 0.254 UBB
ubiquitin B
chr20_+_9146036 0.253 NM_182797
PLCB4
phospholipase C, beta 4
chr2_+_47483750 0.253 NM_000251
MSH2
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr3_+_9950474 0.252 CRELD1
cysteine-rich with EGF-like domains 1
chr17_+_16225075 0.251 NM_018955
UBB
ubiquitin B
chr7_+_99524545 0.246 COPS6
COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)
chr17_-_61253122 0.245 NM_001037325
CCDC46
coiled-coil domain containing 46
chr17_-_43977273 0.244 NM_002145
HOXB2
homeobox B2
chr1_+_43055362 0.244 NM_001017922
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr4_+_82171142 0.243 NM_001201
BMP3
bone morphogenetic protein 3
chr1_+_84316217 0.242 NM_002731
NM_207578
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr7_-_132131742 0.242 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr12_+_109390586 0.237 NM_013300
C12orf24
chromosome 12 open reading frame 24
chr6_+_83959750 0.232 NM_033411
RWDD2A
RWD domain containing 2A
chrX_+_151653874 0.232 NM_001102576
NM_153478
CSAG1

chondrosarcoma associated gene 1

chr1_-_153195188 0.232 NM_020524
PBXIP1
pre-B-cell leukemia homeobox interacting protein 1
chr1_-_1667123 0.231 NM_182838
SLC35E2B
SLC35E2
solute carrier family 35, member E2B
solute carrier family 35, member E2
chr18_+_27925923 0.231 RNF138
ring finger protein 138
chr1_+_208067986 0.230 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr11_+_66162663 0.228 NM_001198843
NM_001198844
NM_002896
RBM4


RNA binding motif protein 4


chr22_-_16070778 0.224 NM_017424
CECR1
cat eye syndrome chromosome region, candidate 1
chr7_+_133982070 0.222 NM_001724
NM_199186
BPGM

2,3-bisphosphoglycerate mutase

chr5_-_94442941 0.222 MCTP1
multiple C2 domains, transmembrane 1
chr19_+_11327061 0.221 NM_001170635
NM_022737
LPPR2

lipid phosphate phosphatase-related protein type 2

chr19_+_1223475 0.220 CIRBP
cold inducible RNA binding protein
chr10_+_35524835 0.219 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr2_-_190893015 0.216 NM_014362
NM_198047
HIBCH

3-hydroxyisobutyryl-CoA hydrolase

chr1_+_208067890 0.216 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr20_-_19984685 0.215 NM_016652
CRNKL1
crooked neck pre-mRNA splicing factor-like 1 (Drosophila)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.