Motif ID: CREB1.p2

Z-value: 1.207


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081030680.214.3e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_67156386 2.627 ARG2
arginase, type II
chr1_-_15723363 2.020 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr18_+_2561509 1.792 NM_006101
NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr14_+_67156323 1.739 NM_001172
ARG2
arginase, type II
chr1_+_26368969 1.720 NM_015871
ZNF593
zinc finger protein 593
chr14_+_67156405 1.681 ARG2
arginase, type II
chr10_-_99084417 1.591 NM_012083
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr11_+_68208583 1.487 GAL
galanin prepropeptide
chr1_-_198905619 1.473 DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr1_+_11963062 1.448 MFN2
mitofusin 2
chr11_+_68208554 1.440 NM_015973
GAL
galanin prepropeptide
chr17_-_74348447 1.422 NM_025090
USP36
ubiquitin specific peptidase 36
chr18_+_2561587 1.372 NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr16_-_3707450 1.301 NM_016292
TRAP1
TNF receptor-associated protein 1
chr9_-_139100923 1.298 LOC100289341
similar to hCG2022304
chr1_-_15723279 1.264 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr1_-_15723305 1.255 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr16_+_18986459 1.240 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr7_-_140270749 1.215 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr19_-_18253259 1.170


chr1_-_92124064 1.158 TGFBR3
transforming growth factor, beta receptor III
chr11_-_28086277 1.156 NM_031217
KIF18A
kinesin family member 18A
chr3_+_186786655 1.089 NM_021627
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr1_-_119484733 1.085 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr1_+_40399618 1.082 NM_012421
RLF
rearranged L-myc fusion
chr1_+_44978145 1.064 KIF2C
kinesin family member 2C
chr4_-_122964232 1.040 CCNA2
cyclin A2
chr16_+_18986417 1.036 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_-_30631912 1.027 GNL1
guanine nucleotide binding protein-like 1
chr13_-_35769968 1.027 NM_001198910
NM_001144981
NM_001144982
NM_001144983
NM_001144984
NM_001144985
NM_001144986
NM_001198908
C13orf38-SOHLH2
C13orf38






C13orf38-SOHLH2 readthrough
chromosome 13 open reading frame 38






chr12_+_131194931 1.017 NM_024078
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr14_-_54438913 1.003 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr11_-_28086263 0.997 KIF18A
kinesin family member 18A
chr1_+_40399642 0.996 RLF
rearranged L-myc fusion
chr1_+_44978120 0.970 KIF2C
kinesin family member 2C
chr12_-_10657397 0.967 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr1_+_44978053 0.936 NM_006845
KIF2C
kinesin family member 2C
chr18_-_2561422 0.934 NM_022840
METTL4
methyltransferase like 4
chr4_-_122964428 0.914 NM_001237
CCNA2
cyclin A2
chr6_-_49712483 0.910 NM_000324
RHAG
Rh-associated glycoprotein
chr1_+_149247519 0.910 NM_021222
PRUNE
prune homolog (Drosophila)
chr16_+_1979959 0.907 NM_004209
SYNGR3
synaptogyrin 3
chr17_+_632356 0.901 RNMTL1
RNA methyltransferase like 1
chr9_-_139473606 0.889 NM_001130969
NM_001130970
NM_001130971
NM_001178064
NM_015537
NELF




nasal embryonic LHRH factor




chr14_-_103058568 0.856 CKB
creatine kinase, brain
chr7_+_116447499 0.841 ST7
suppression of tumorigenicity 7
chr16_+_18986721 0.839 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_30632464 0.832 NM_001077497
NM_025263
PRR3

proline rich 3

chr11_-_118757574 0.817 NM_004205
USP2
ubiquitin specific peptidase 2
chr17_+_7096095 0.817 NM_203415
NM_015362
NM_203413
NM_203414
C17orf81



chromosome 17 open reading frame 81



chr11_-_3775547 0.816 NM_005387
NM_016320
NM_139131
NM_139132
NUP98



nucleoporin 98kDa



chr9_+_132990760 0.816 NM_005085
NUP214
nucleoporin 214kDa
chr1_-_159413833 0.810 NM_003779
B4GALT3
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr17_+_632262 0.799 NM_018146
RNMTL1
RNA methyltransferase like 1
chr17_-_39556535 0.791 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr6_-_26393705 0.773 NM_003543
HIST1H4H
histone cluster 1, H4h
chr1_-_52642646 0.764 NM_001190818
NM_001190819
NM_004153
ORC1


origin recognition complex, subunit 1


chr11_-_62363551 0.763 WDR74
WD repeat domain 74
chr16_-_66251611 0.759 ACD
adrenocortical dysplasia homolog (mouse)
chr6_-_30631481 0.754 GNL1
guanine nucleotide binding protein-like 1
chr8_-_17148637 0.752 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr16_+_79598016 0.740 CENPN
centromere protein N
chr1_+_11963091 0.739 MFN2
mitofusin 2
chr10_+_85889164 0.733 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr17_+_7096545 0.726 C17orf81
chromosome 17 open reading frame 81
chr8_-_17148474 0.721 CNOT7
CCR4-NOT transcription complex, subunit 7
chr11_-_118757477 0.716 USP2
ubiquitin specific peptidase 2
chr17_+_8093319 0.715 NM_012393
PFAS
phosphoribosylformylglycinamidine synthase
chr6_+_44322764 0.705 NM_007355
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr10_+_21863099 0.705 NM_001195627
NM_001195628
NM_001195630
NM_004641
MLLT10



myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10



chr7_+_116447527 0.703 ST7
suppression of tumorigenicity 7
chr17_-_632135 0.697 NM_016080
GLOD4
glyoxalase domain containing 4
chr6_+_44322831 0.692 HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr10_+_22674379 0.682 NM_012443
NM_172242
SPAG6

sperm associated antigen 6

chr14_-_103065089 0.681


chr1_+_70649451 0.675 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr11_-_28086222 0.667 KIF18A
kinesin family member 18A
chr2_+_74914742 0.667 HK2
hexokinase 2
chr16_-_20819061 0.665 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr15_+_38843535 0.658 NM_005258
GCHFR
GTP cyclohydrolase I feedback regulator
chr11_+_34083784 0.657 NAT10
N-acetyltransferase 10 (GCN5-related)
chr5_+_43157398 0.655 NM_003432
ZNF131
zinc finger protein 131
chr14_+_92721048 0.655 NM_015676
NM_001098621
C14orf109

chromosome 14 open reading frame 109

chr10_+_21863272 0.653 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr15_+_38648823 0.650 NM_152260
RPUSD2
RNA pseudouridylate synthase domain containing 2
chr21_+_43903803 0.644 NM_015056
RRP1B
ribosomal RNA processing 1 homolog B (S. cerevisiae)
chr5_+_44844724 0.639 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr18_-_257987 0.636 NM_005131
THOC1
THO complex 1
chr5_+_68425672 0.634 SLC30A5
solute carrier family 30 (zinc transporter), member 5
chr15_+_38648819 0.633 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr1_-_243092581 0.633 HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr19_+_44113402 0.632 NM_021107
NM_033363
MRPS12

mitochondrial ribosomal protein S12

chr17_-_39556483 0.624 HDAC5
histone deacetylase 5
chr17_-_74348203 0.622 USP36
ubiquitin specific peptidase 36
chr7_+_99865189 0.620 NM_019606
MEPCE
methylphosphate capping enzyme
chr19_-_18253413 0.619 NM_005354
JUND
jun D proto-oncogene
chr5_+_68425573 0.618 NM_024055
SLC30A5
solute carrier family 30 (zinc transporter), member 5
chr15_+_64584686 0.617 ZWILCH
Zwilch, kinetochore associated, homolog (Drosophila)
chr20_+_41729161 0.615 MYBL2
v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr11_+_66367458 0.609 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein peptidase (S. cerevisiae)

chr2_+_96365233 0.607 NCAPH
non-SMC condensin I complex, subunit H
chr1_-_227710619 0.604 NUP133
nucleoporin 133kDa
chr16_-_29914816 0.602 NM_003609
HIRIP3
HIRA interacting protein 3
chr15_+_38648801 0.598 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr11_-_77963366 0.596 NARS2
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr3_-_38046034 0.592 NM_006225
PLCD1
phospholipase C, delta 1
chr22_-_18484428 0.587 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr16_-_66252103 0.586 NM_001082486
NM_001082487
NM_022914
ACD


adrenocortical dysplasia homolog (mouse)


chr11_-_77963517 0.586 NM_024678
NARS2
asparaginyl-tRNA synthetase 2, mitochondrial (putative)
chr7_+_106991638 0.583 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr8_-_145713959 0.580 NM_004260
RECQL4
RecQ protein-like 4
chr3_+_52694975 0.580 NM_014366
NM_206825
NM_206826
GNL3


guanine nucleotide binding protein-like 3 (nucleolar)


chr19_+_40795456 0.576 NM_015302
HAUS5
HAUS augmin-like complex, subunit 5
chr6_-_31954730 0.574 SLC44A4
solute carrier family 44, member 4
chr1_+_10193267 0.569 NM_015074
NM_183416
KIF1B

kinesin family member 1B

chr6_-_27222556 0.565 NM_080593
HIST1H2BK
histone cluster 1, H2bk
chr15_+_38648783 0.564 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr1_+_11962824 0.557 NM_001127660
NM_014874
MFN2

mitofusin 2

chr1_-_227710700 0.556 NM_018230
NUP133
nucleoporin 133kDa
chr6_-_34772565 0.553 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr1_-_226712140 0.552 NM_033445
HIST3H2A
histone cluster 3, H2a
chr16_+_87300385 0.552 NM_001012759
NM_001012762
CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr8_+_23442331 0.550 SLC25A37
solute carrier family 25, member 37
chr3_+_128799964 0.549 MCM2
minichromosome maintenance complex component 2
chr3_+_128799902 0.545 NM_004526
MCM2
minichromosome maintenance complex component 2
chr19_-_5671155 0.543 LONP1
lon peptidase 1, mitochondrial
chr6_-_43135092 0.539 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr19_-_60360768 0.535 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr12_+_131194967 0.535 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr10_+_21863388 0.532 MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr19_-_60610971 0.531 UBE2S
ubiquitin-conjugating enzyme E2S
chr10_-_23043449 0.530 NM_005028
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr1_+_220857774 0.526 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr19_-_5671136 0.525 LONP1
lon peptidase 1, mitochondrial
chr5_+_43157349 0.519 ZNF131
zinc finger protein 131
chr17_-_70380663 0.517 NM_004110
NM_024417
FDXR

ferredoxin reductase

chr7_+_55987046 0.516 NM_015969
MRPS17
mitochondrial ribosomal protein S17
chr4_-_80079393 0.516 NM_001040202
PAQR3
progestin and adipoQ receptor family member III
chr20_+_62083020 0.512


chr17_-_71960867 0.511 NM_022066
UBE2O
ubiquitin-conjugating enzyme E2O
chr11_+_34083686 0.501 NM_001144030
NM_024662
NAT10

N-acetyltransferase 10 (GCN5-related)

chr19_+_63747678 0.496 TRIM28
tripartite motif containing 28
chr11_+_69794419 0.495 NM_003626
NM_177423
PPFIA1

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1

chr12_-_131194794 0.492 NM_175066
DDX51
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr20_+_36810510 0.491 NM_024855
ACTR5
ARP5 actin-related protein 5 homolog (yeast)
chr12_-_93377584 0.488 CCDC41
coiled-coil domain containing 41
chr5_+_137829065 0.488 EGR1
early growth response 1
chr13_-_29937966 0.487 HMGB1
HMGB1P6
high-mobility group box 1
high-mobility group box 1 pseudogene 6
chr1_-_1274618 0.483 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr20_+_62082937 0.482 PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr3_+_128799961 0.481 MCM2
minichromosome maintenance complex component 2
chr4_+_144654005 0.481 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr19_-_52308848 0.477 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr21_-_43400672 0.475 U2AF1
U2 small nuclear RNA auxiliary factor 1
chr6_-_31954795 0.473 NM_001178044
NM_025257
SLC44A4

solute carrier family 44, member 4

chr2_-_128285136 0.472 WDR33
WD repeat domain 33
chr19_-_45028784 0.470 FBL
fibrillarin
chr16_+_84202515 0.470 NM_001134473
KIAA0182
KIAA0182
chr20_-_22512893 0.465 FOXA2
forkhead box A2
chr15_+_39739864 0.463 NM_001080541
NM_001164273
MGA

MAX gene associated

chr22_-_25209724 0.461 HPS4
Hermansky-Pudlak syndrome 4
chrX_+_102356659 0.460 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr4_+_170778303 0.459 CLCN3
chloride channel 3
chr6_-_32047637 0.457 DOM3Z
dom-3 homolog Z (C. elegans)
chr8_-_145485822 0.453 BOP1
block of proliferation 1
chr3_+_159771646 0.449 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr19_+_13124889 0.448 IER2
immediate early response 2
chr5_-_37406939 0.447 NM_153485
NUP155
nucleoporin 155kDa
chrX_+_30581377 0.445 NM_000167
NM_001128127
NM_203391
GK


glycerol kinase


chr12_-_110764059 0.444 C12orf47
chromosome 12 open reading frame 47
chr17_-_4967120 0.442 NM_014519
ZNF232
zinc finger protein 232
chr16_+_66855827 0.441 NM_001076785
NM_003983
SLC7A6

solute carrier family 7 (cationic amino acid transporter, y+ system), member 6

chr6_-_34772495 0.441 C6orf106
chromosome 6 open reading frame 106
chr2_-_156897286 0.439 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr17_-_45110339 0.439 NM_001007226
NM_001007227
NM_001007228
NM_001007229
NM_001007230
NM_003563
SPOP





speckle-type POZ protein





chr3_+_73128629 0.438 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr11_-_3775282 0.438 NUP98
nucleoporin 98kDa
chr19_-_45028837 0.437 FBL
fibrillarin
chr6_-_135860479 0.437 AHI1
Abelson helper integration site 1
chr21_-_43172729 0.435 NM_018669
NM_033661
WDR4

WD repeat domain 4

chr12_-_81276285 0.432 NM_014167
CCDC59
coiled-coil domain containing 59
chr1_-_233358829 0.432 NM_014765
TOMM20
translocase of outer mitochondrial membrane 20 homolog (yeast)
chr19_+_50141068 0.432 NM_000483
APOC2
apolipoprotein C-II
chr3_+_43303005 0.430 NM_001100594
NM_017719
SNRK

SNF related kinase

chr13_-_29938029 0.430 NM_002128
HMGB1
high-mobility group box 1
chr19_-_18253436 0.428 JUND
jun D proto-oncogene
chr2_+_85683473 0.428 USP39
ubiquitin specific peptidase 39
chr20_+_62082908 0.426 PRPF6
PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)
chr12_+_110764164 0.425 MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr15_-_89338728 0.424 NM_003981
NM_199413
NM_199414
PRC1


protein regulator of cytokinesis 1


chr10_+_14960787 0.423 NM_001193424
NM_001193426
NM_001193425
NM_001193427
NM_024670
SUV39H2




suppressor of variegation 3-9 homolog 2 (Drosophila)




chr19_-_52426055 0.422 NM_014417
BBC3
BCL2 binding component 3
chr5_-_37406955 0.420 NUP155
nucleoporin 155kDa
chr11_+_3775529 0.418 NM_001145438
PGAP2
post-GPI attachment to proteins 2
chr10_+_70385889 0.417 NM_004728
DDX21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
chr19_-_37857897 0.417 NM_032139
ANKRD27
ankyrin repeat domain 27 (VPS9 domain)
chr12_+_110764427 0.413 MAPKAPK5
mitogen-activated protein kinase-activated protein kinase 5
chr1_+_39229474 0.413 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr21_-_43400750 0.412 NM_001025203
NM_001025204
NM_006758
U2AF1


U2 small nuclear RNA auxiliary factor 1


chr17_-_46479127 0.412 SPAG9
sperm associated antigen 9

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.69 2.49e-14 GO:0090304 nucleic acid metabolic process
1.59 3.26e-14 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.42 1.67e-13 GO:0006396 RNA processing
1.42 7.29e-13 GO:0044260 cellular macromolecule metabolic process
1.76 9.24e-13 GO:0016070 RNA metabolic process
1.49 1.27e-11 GO:0034641 cellular nitrogen compound metabolic process
1.68 4.05e-11 GO:0010467 gene expression
1.46 1.01e-10 GO:0006807 nitrogen compound metabolic process
1.28 1.86e-10 GO:0044237 cellular metabolic process
1.33 3.98e-09 GO:0043170 macromolecule metabolic process
2.25 1.43e-08 GO:0016071 mRNA metabolic process
2.47 4.48e-08 GO:0006397 mRNA processing
1.25 4.76e-08 GO:0044238 primary metabolic process
2.59 3.18e-07 GO:0008380 RNA splicing
1.22 4.53e-07 GO:0008152 metabolic process
2.95 4.93e-07 GO:0000375 RNA splicing, via transesterification reactions
2.96 7.10e-07 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.96 7.10e-07 GO:0000398 nuclear mRNA splicing, via spliceosome
3.35 5.30e-06 GO:0050657 nucleic acid transport
3.35 5.30e-06 GO:0050658 RNA transport
3.35 5.30e-06 GO:0051236 establishment of RNA localization
3.43 9.93e-06 GO:0051028 mRNA transport
3.26 1.05e-05 GO:0006403 RNA localization
2.98 1.02e-04 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.90 1.03e-04 GO:0051276 chromosome organization
1.84 1.48e-04 GO:0022403 cell cycle phase
1.76 2.34e-04 GO:0022402 cell cycle process
1.65 2.93e-04 GO:0007049 cell cycle
2.88 3.75e-04 GO:0071103 DNA conformation change
1.49 6.31e-04 GO:0006996 organelle organization
1.46 1.07e-03 GO:0009059 macromolecule biosynthetic process
2.02 1.13e-03 GO:0000279 M phase
1.46 1.29e-03 GO:0034645 cellular macromolecule biosynthetic process
1.84 1.31e-03 GO:0000278 mitotic cell cycle
2.81 1.61e-03 GO:0006333 chromatin assembly or disassembly
2.30 1.73e-03 GO:0034660 ncRNA metabolic process
3.73 3.08e-03 GO:0031124 mRNA 3'-end processing
1.86 3.22e-03 GO:0044265 cellular macromolecule catabolic process
2.16 4.75e-03 GO:0000087 M phase of mitotic cell cycle
4.17 6.07e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
1.86 9.91e-03 GO:0006325 chromatin organization
2.35 1.02e-02 GO:0022613 ribonucleoprotein complex biogenesis
1.79 1.74e-02 GO:0034621 cellular macromolecular complex subunit organization
1.93 1.81e-02 GO:0034622 cellular macromolecular complex assembly
3.27 2.23e-02 GO:0031123 RNA 3'-end processing
2.35 2.80e-02 GO:0006913 nucleocytoplasmic transport
2.07 3.03e-02 GO:0000280 nuclear division
2.07 3.03e-02 GO:0007067 mitosis
2.24 3.10e-02 GO:0071843 cellular component biogenesis at cellular level
3.47 3.37e-02 GO:0006406 mRNA export from nucleus
1.31 3.42e-02 GO:0044249 cellular biosynthetic process
2.32 3.62e-02 GO:0051169 nuclear transport
3.04 3.67e-02 GO:0051168 nuclear export
3.28 3.90e-02 GO:0006405 RNA export from nucleus
3.13 4.27e-02 GO:0000956 nuclear-transcribed mRNA catabolic process
2.59 4.49e-02 GO:0042254 ribosome biogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 2.53e-18 GO:0043231 intracellular membrane-bounded organelle
1.26 3.92e-18 GO:0043227 membrane-bounded organelle
1.83 4.99e-18 GO:0031981 nuclear lumen
1.40 6.48e-17 GO:0005634 nucleus
1.72 7.37e-17 GO:0044428 nuclear part
1.70 9.52e-17 GO:0070013 intracellular organelle lumen
1.66 1.25e-15 GO:0031974 membrane-enclosed lumen
1.67 1.95e-15 GO:0043233 organelle lumen
1.16 2.25e-14 GO:0044424 intracellular part
1.87 7.72e-14 GO:0005654 nucleoplasm
1.35 2.63e-13 GO:0044446 intracellular organelle part
1.20 3.19e-13 GO:0043229 intracellular organelle
1.20 6.26e-13 GO:0043226 organelle
1.15 1.02e-12 GO:0005622 intracellular
1.33 2.32e-12 GO:0044422 organelle part
1.41 1.78e-09 GO:0032991 macromolecular complex
2.12 3.47e-08 GO:0005694 chromosome
2.03 5.13e-06 GO:0005730 nucleolus
2.04 1.58e-05 GO:0044427 chromosomal part
1.96 3.61e-05 GO:0030529 ribonucleoprotein complex
3.62 1.00e-04 GO:0071013 catalytic step 2 spliceosome
1.35 2.54e-04 GO:0043228 non-membrane-bounded organelle
1.35 2.54e-04 GO:0043232 intracellular non-membrane-bounded organelle
2.80 4.58e-04 GO:0005681 spliceosomal complex
1.30 1.25e-03 GO:0043234 protein complex
1.63 4.68e-03 GO:0044451 nucleoplasm part
1.33 7.44e-03 GO:0005829 cytosol
1.12 9.85e-03 GO:0005737 cytoplasm
2.38 3.07e-02 GO:0000793 condensed chromosome
2.48 3.34e-02 GO:0016607 nuclear speck

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.47 2.47e-10 GO:0003676 nucleic acid binding
2.02 3.47e-10 GO:0003723 RNA binding
1.16 5.85e-04 GO:0005515 protein binding
1.36 1.16e-03 GO:0000166 nucleotide binding
1.35 2.20e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.39 2.49e-02 GO:0005524 ATP binding
1.37 4.15e-02 GO:0030554 adenyl nucleotide binding
2.64 4.38e-02 GO:0008026 ATP-dependent helicase activity
2.64 4.38e-02 GO:0070035 purine NTP-dependent helicase activity
1.33 4.76e-02 GO:0017076 purine nucleotide binding
1.37 4.98e-02 GO:0032559 adenyl ribonucleotide binding