Motif ID: CREB1.p2

Z-value: 1.207


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB1chr2_+_2081030680.214.3e-01Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_67156386 2.627 ARG2
arginase, type II
chr1_-_15723363 2.020 NM_001229
NM_032996
 CASP9

caspase 9, apoptosis-related cysteine peptidase

chr18_+_2561509 1.792 NM_006101
 NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr14_+_67156323 1.739 NM_001172
 ARG2
arginase, type II
chr1_+_26368969 1.720 NM_015871
 ZNF593
zinc finger protein 593
chr14_+_67156405 1.681 ARG2
arginase, type II
chr10_-_99084417 1.591 NM_012083
 FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr11_+_68208583 1.487 GAL
galanin prepropeptide
chr1_-_198905619 1.473 DDX59
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59
chr1_+_11963062 1.448 MFN2
mitofusin 2
chr11_+_68208554 1.440 NM_015973
 GAL
galanin prepropeptide
chr17_-_74348447 1.422 NM_025090
 USP36
ubiquitin specific peptidase 36
chr18_+_2561587 1.372 NDC80
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr16_-_3707450 1.301 NM_016292
 TRAP1
TNF receptor-associated protein 1
chr9_-_139100923 1.298 LOC100289341
similar to hCG2022304
chr1_-_15723279 1.264 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr1_-_15723305 1.255 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr16_+_18986459 1.240 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr7_-_140270749 1.215 NM_004333
 BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr19_-_18253259 1.170



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 56 entries
enrichment   p-value GO term description
4.17 6.07e-03 GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
3.73 3.08e-03 GO:0031124 mRNA 3'-end processing
3.47 3.37e-02 GO:0006406 mRNA export from nucleus
3.43 9.93e-06 GO:0051028 mRNA transport
3.35 5.30e-06 GO:0050657 nucleic acid transport
3.35 5.30e-06 GO:0050658 RNA transport
3.35 5.30e-06 GO:0051236 establishment of RNA localization
3.28 3.90e-02 GO:0006405 RNA export from nucleus
3.27 2.23e-02 GO:0031123 RNA 3'-end processing
3.26 1.05e-05 GO:0006403 RNA localization
3.13 4.27e-02 GO:0000956 nuclear-transcribed mRNA catabolic process
3.04 3.67e-02 GO:0051168 nuclear export
2.98 1.02e-04 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
2.96 7.10e-07 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.96 7.10e-07 GO:0000398 nuclear mRNA splicing, via spliceosome
2.95 4.93e-07 GO:0000375 RNA splicing, via transesterification reactions
2.88 3.75e-04 GO:0071103 DNA conformation change
2.81 1.61e-03 GO:0006333 chromatin assembly or disassembly
2.59 3.18e-07 GO:0008380 RNA splicing
2.59 4.49e-02 GO:0042254 ribosome biogenesis

Gene overrepresentation in compartment category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
3.62 1.00e-04 GO:0071013 catalytic step 2 spliceosome
2.80 4.58e-04 GO:0005681 spliceosomal complex
2.48 3.34e-02 GO:0016607 nuclear speck
2.38 3.07e-02 GO:0000793 condensed chromosome
2.12 3.47e-08 GO:0005694 chromosome
2.04 1.58e-05 GO:0044427 chromosomal part
2.03 5.13e-06 GO:0005730 nucleolus
1.96 3.61e-05 GO:0030529 ribonucleoprotein complex
1.87 7.72e-14 GO:0005654 nucleoplasm
1.83 4.99e-18 GO:0031981 nuclear lumen
1.72 7.37e-17 GO:0044428 nuclear part
1.70 9.52e-17 GO:0070013 intracellular organelle lumen
1.67 1.95e-15 GO:0043233 organelle lumen
1.66 1.25e-15 GO:0031974 membrane-enclosed lumen
1.63 4.68e-03 GO:0044451 nucleoplasm part
1.41 1.78e-09 GO:0032991 macromolecular complex
1.40 6.48e-17 GO:0005634 nucleus
1.35 2.63e-13 GO:0044446 intracellular organelle part
1.35 2.54e-04 GO:0043228 non-membrane-bounded organelle
1.35 2.54e-04 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
2.64 4.38e-02 GO:0008026 ATP-dependent helicase activity
2.64 4.38e-02 GO:0070035 purine NTP-dependent helicase activity
2.02 3.47e-10 GO:0003723 RNA binding
1.47 2.47e-10 GO:0003676 nucleic acid binding
1.39 2.49e-02 GO:0005524 ATP binding
1.37 4.15e-02 GO:0030554 adenyl nucleotide binding
1.37 4.98e-02 GO:0032559 adenyl ribonucleotide binding
1.36 1.16e-03 GO:0000166 nucleotide binding
1.35 2.20e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.33 4.76e-02 GO:0017076 purine nucleotide binding
1.16 5.85e-04 GO:0005515 protein binding