Motif ID: HNF4A_NR2F1,2.p2

Z-value: 4.018


Transcription factors associated with HNF4A_NR2F1,2.p2:

Gene SymbolEntrez IDGene Name
HNF4A 3172 hepatocyte nuclear factor 4, alpha
NR2F1 7025 nuclear receptor subfamily 2, group F, member 1
NR2F2 7026 nuclear receptor subfamily 2, group F, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HNF4Achr20_+_424632790.467.3e-02Click!
NR2F1chr5_+_929463480.439.4e-02Click!
NR2F2chr15_+_94677572-0.312.4e-01Click!


Activity profile for motif HNF4A_NR2F1,2.p2.

activity profile for motif HNF4A_NR2F1,2.p2


Sorted Z-values histogram for motif HNF4A_NR2F1,2.p2

Sorted Z-values for motif HNF4A_NR2F1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF4A_NR2F1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_24394281 14.155 PIPOX
pipecolic acid oxidase
chr14_-_93924873 13.509 NM_000295
 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_+_31731647 10.530 NM_019101
 APOM
apolipoprotein M
chr6_+_31731667 10.473 APOM
apolipoprotein M
chr1_-_167822248 10.262 F5
coagulation factor V (proaccelerin, labile factor)
chr12_+_51783540 9.920 NM_003578
 SOAT2
sterol O-acyltransferase 2
chr12_+_51783554 9.131 SOAT2
sterol O-acyltransferase 2
chr10_-_101831579 8.743 NM_001308
 CPN1
carboxypeptidase N, polypeptide 1
chr6_+_32021793 8.670 CFB
complement factor B
chr6_+_32090516 8.509 NM_007293
NM_001002029
 C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr5_-_42847716 8.438 NM_001085486
NM_001093726
NM_005410
 SEPP1


selenoprotein P, plasma, 1


chr10_+_102722275 8.226 NM_017893
 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_-_167822334 8.175 NM_000130
 F5
coagulation factor V (proaccelerin, labile factor)
chr1_-_159459814 7.740 APOA2
apolipoprotein A-II
chr11_+_46697345 7.540 F2
coagulation factor II (thrombin)
chr17_+_24394043 7.492 NM_016518
 PIPOX
pipecolic acid oxidase
chr11_-_116213511 7.380 NM_000039
 APOA1
apolipoprotein A-I
chr11_+_46697312 7.152 NM_000506
 F2
coagulation factor II (thrombin)
chr17_-_31353196 7.106 NM_032965
 CCL15
chemokine (C-C motif) ligand 15
chr14_-_23847024 7.031 CIDEB
cell death-inducing DFFA-like effector b

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.76 1.53e-02 GO:0032787 monocarboxylic acid metabolic process
1.54 3.18e-03 GO:0006082 organic acid metabolic process
1.53 4.71e-03 GO:0019752 carboxylic acid metabolic process
1.53 4.71e-03 GO:0043436 oxoacid metabolic process
1.50 1.47e-02 GO:0042180 cellular ketone metabolic process
1.36 1.59e-04 GO:0044281 small molecule metabolic process
1.14 4.76e-04 GO:0008152 metabolic process
1.13 3.00e-02 GO:0044238 primary metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.42 2.53e-02 GO:0044432 endoplasmic reticulum part
1.12 4.83e-02 GO:0044444 cytoplasmic part
1.09 2.90e-02 GO:0005737 cytoplasm

Nothing significant found in function category.