Motif ID: HIF1A.p2

Z-value: 1.958


Transcription factors associated with HIF1A.p2:

Gene SymbolEntrez IDGene Name
HIF1A 3091 hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HIF1Achr14_+_61231795-0.116.7e-01Click!


Activity profile for motif HIF1A.p2.

activity profile for motif HIF1A.p2


Sorted Z-values histogram for motif HIF1A.p2

Sorted Z-values for motif HIF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HIF1A.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_13866451 4.909 GPM6B
glycoprotein M6B
chrX_-_13866565 3.347 NM_001001994
 GPM6B
glycoprotein M6B
chr12_-_21702036 2.887 LDHB
lactate dehydrogenase B
chr12_-_21702021 2.857 LDHB
lactate dehydrogenase B
chr12_-_21701985 2.760 NM_001174097
 LDHB
lactate dehydrogenase B
chr12_-_21702000 2.719 LDHB
lactate dehydrogenase B
chr12_-_21702046 2.591 NM_002300
 LDHB
lactate dehydrogenase B
chrX_-_13866366 2.411


chr8_+_95722448 2.228 ESRP1
epithelial splicing regulatory protein 1
chr5_+_17270474 1.997 NM_006317
 BASP1
brain abundant, membrane attached signal protein 1
chr5_+_17270781 1.932 BASP1
brain abundant, membrane attached signal protein 1
chr11_+_69602055 1.884 NM_018043
 ANO1
anoctamin 1, calcium activated chloride channel
chr10_+_3099708 1.701 NM_002627
 PFKP
phosphofructokinase, platelet
chr1_+_231816372 1.684 NM_002245
 KCNK1
potassium channel, subfamily K, member 1
chr3_+_157874898 1.647 NM_015508
 TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr11_+_20341806 1.601 NM_006410
NM_001098521
 HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr2_-_96174865 1.553 NM_004418
 DUSP2
dual specificity phosphatase 2
chr4_-_143987053 1.533 NM_001101669
NM_003866
 INPP4B

inositol polyphosphate-4-phosphatase, type II, 105kDa

chr10_+_17312654 1.480 VIM
vimentin
chr17_-_3546047 1.470 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.97 2.60e-02 GO:0050770 regulation of axonogenesis
2.45 2.26e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.43 2.74e-02 GO:0022604 regulation of cell morphogenesis
2.38 3.96e-02 GO:0010975 regulation of neuron projection development
1.97 4.56e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.20 8.30e-03 GO:0044260 cellular macromolecule metabolic process
1.17 6.51e-04 GO:0044237 cellular metabolic process
1.08 2.78e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
2.18 1.88e-02 GO:0031965 nuclear membrane
1.97 3.72e-03 GO:0005635 nuclear envelope
1.32 5.51e-04 GO:0005829 cytosol
1.25 4.93e-02 GO:0044428 nuclear part
1.18 8.62e-04 GO:0005634 nucleus
1.16 1.84e-07 GO:0005737 cytoplasm
1.15 2.18e-03 GO:0044444 cytoplasmic part
1.14 2.82e-02 GO:0044446 intracellular organelle part
1.13 3.03e-11 GO:0044424 intracellular part
1.13 6.23e-05 GO:0043231 intracellular membrane-bounded organelle
1.13 8.32e-05 GO:0043227 membrane-bounded organelle
1.12 6.76e-11 GO:0005622 intracellular
1.12 6.80e-06 GO:0043226 organelle
1.12 1.08e-05 GO:0043229 intracellular organelle
1.04 1.87e-02 GO:0044464 cell part
1.04 1.94e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.13 9.33e-04 GO:0005515 protein binding