Motif ID: SNAI1..3.p2

Z-value: 4.760


Transcription factors associated with SNAI1..3.p2:

Gene SymbolEntrez IDGene Name
SNAI1 6615 snail homolog 1 (Drosophila)
SNAI2 6591 snail homolog 2 (Drosophila)
SNAI3 333929 snail homolog 3 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SNAI1chr20_+_48032918-0.185.0e-01Click!
SNAI2chr8_-_499963530.155.8e-01Click!


Activity profile for motif SNAI1..3.p2.

activity profile for motif SNAI1..3.p2


Sorted Z-values histogram for motif SNAI1..3.p2

Sorted Z-values for motif SNAI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SNAI1..3.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_43446937 15.905 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_43447078 15.880 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_43447262 15.792 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr2_-_166359016 14.645 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_+_181422016 13.823 LAMC2
laminin, gamma 2
chr4_+_75529716 12.791 NM_001657
AREG
amphiregulin
chr16_+_67236730 12.005 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr1_+_181421984 9.218 LAMC2
laminin, gamma 2
chr1_+_181421796 8.856 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr4_+_75699652 8.567 NM_001657
AREG
amphiregulin
chr14_-_66948612 8.498 PLEK2
pleckstrin 2
chr14_-_66948523 8.460 NM_016445
PLEK2
pleckstrin 2
chr14_-_60818263 8.272 NM_001017970
TMEM30B
transmembrane protein 30B
chr18_+_19706979 8.088 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr17_-_37196463 7.741 NM_002230
NM_021991
JUP

junction plakoglobin

chr1_+_46418786 7.620 TSPAN1
tetraspanin 1
chr11_+_120828058 7.617 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr20_-_6051562 7.431 FERMT1
fermitin family member 1
chr18_+_19523526 6.716 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chr16_-_4927057 6.709 NM_002705
PPL
periplakin
chr16_+_67328693 6.658 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chrX_+_130985316 6.537 NM_001042452
MST4
serine/threonine protein kinase MST4
chr18_+_27332024 6.512 NM_001943
DSG2
desmoglein 2
chr14_-_60817709 6.499 TMEM30B
transmembrane protein 30B
chr1_+_60053050 6.353 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr16_+_67236699 6.329 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr17_-_37034288 6.306 NM_000422
KRT17
keratin 17
chr19_+_40299058 6.180 FXYD3
FXYD domain containing ion transport regulator 3
chr8_+_95722448 6.167 ESRP1
epithelial splicing regulatory protein 1
chr1_+_1971762 6.156 NM_002744
PRKCZ
protein kinase C, zeta
chr12_-_6355165 6.044 NM_001038
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr19_-_10558906 5.916 NM_005498
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr1_+_154297588 5.856 NM_020387
RAB25
RAB25, member RAS oncogene family
chr21_-_42060334 5.828 RIPK4
receptor-interacting serine-threonine kinase 4
chr17_+_71033339 5.787 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr12_+_51628921 5.759 NM_199187
NM_000224
KRT18

keratin 18

chr12_+_50913220 5.742 NM_005556
KRT7
keratin 7
chr18_-_72973750 5.726 NM_001025100
NM_001025101
MBP

myelin basic protein

chr19_+_40431122 5.678 LSR
lipolysis stimulated lipoprotein receptor
chr21_-_42060266 5.666 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr16_+_67328715 5.636 CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr12_+_50913274 5.575 KRT7
keratin 7
chr3_-_112796855 5.511 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr18_-_72973698 5.164 MBP
myelin basic protein
chr8_+_102574012 5.043 GRHL2
grainyhead-like 2 (Drosophila)
chr17_-_77635703 5.017 FASN
fatty acid synthase
chr8_+_102573837 4.823 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr12_+_51629164 4.813 KRT18
keratin 18
chr6_+_7486891 4.694 DSP
desmoplakin
chr8_+_95722516 4.579 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr6_-_10527772 4.534 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_95722575 4.522 ESRP1
epithelial splicing regulatory protein 1
chr2_+_47449790 4.474 NM_002354
EPCAM
epithelial cell adhesion molecule
chr21_+_17807167 4.232 NM_001338
CXADR
coxsackie virus and adenovirus receptor
chr11_+_384238 4.211 PKP3
plakophilin 3
chr8_+_86563382 4.080 NM_000067
CA2
carbonic anhydrase II
chr11_+_66580861 4.073 NM_014578
RHOD
ras homolog gene family, member D
chr19_+_40431359 4.034 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr1_-_159257567 4.011 F11R
F11 receptor
chr19_+_43971689 4.010 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr1_-_159257486 3.881 F11R
F11 receptor
chr8_-_81246215 3.765 NM_001025253
NM_005079
TPD52

tumor protein D52

chr2_+_47449951 3.760 EPCAM
epithelial cell adhesion molecule
chr6_-_136913649 3.755 NM_001198616
NM_001198617
NM_003980
MAP7


microtubule-associated protein 7


chr6_+_30402203 3.752


chr15_+_99237555 3.727 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr1_-_94779727 3.724 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chrX_+_130984912 3.657 NM_001042453
NM_016542
MST4

serine/threonine protein kinase MST4

chr16_-_66827449 3.642 NM_024939
ESRP2
epithelial splicing regulatory protein 2
chr17_-_77634455 3.632 FASN
fatty acid synthase
chr5_+_76150588 3.626 NM_005242
F2RL1
coagulation factor II (thrombin) receptor-like 1
chr4_+_85723080 3.567 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr12_-_6354650 3.506 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr1_-_58815415 3.497 TACSTD2
tumor-associated calcium signal transducer 2
chr15_+_38923470 3.436 NM_003710
NM_181642
SPINT1

serine peptidase inhibitor, Kunitz type 1

chr17_+_2627099 3.429 RAP1GAP2
RAP1 GTPase activating protein 2
chr10_+_8137356 3.426 GATA3
GATA binding protein 3
chr19_+_40431618 3.419 LSR
lipolysis stimulated lipoprotein receptor
chr14_-_23106372 3.389 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr15_+_38923914 3.293 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr14_-_54438913 3.280 NM_000161
NM_001024024
NM_001024070
NM_001024071
GCH1



GTP cyclohydrolase 1



chr7_+_16759845 3.280 NM_014399
TSPAN13
tetraspanin 13
chr11_+_32808045 3.265 NM_024081
PRRG4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr5_+_167651063 3.227 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr4_-_9632192 3.221 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr4_-_11039600 3.208 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr15_+_38332640 3.190 PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr1_-_6585268 3.175 KLHL21
kelch-like 21 (Drosophila)
chr11_-_119514011 3.110 TRIM29
tripartite motif containing 29
chr1_-_199635339 3.097 LAD1
ladinin 1
chr11_+_384199 3.076 NM_007183
PKP3
plakophilin 3
chr1_+_151223180 3.021 NM_005987
SPRR1A
small proline-rich protein 1A
chr6_-_47362102 3.011 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr4_-_35922288 3.006 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_72093739 2.993 NM_006456
ST6GALNAC2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr18_+_27281729 2.991 NM_001944
DSG3
desmoglein 3
chr19_-_12747263 2.950 HOOK2
hook homolog 2 (Drosophila)
chr14_-_50480857 2.948 NM_001163940
NM_002863
PYGL

phosphorylase, glycogen, liver

chr3_+_143797895 2.899 NM_001145319
PLS1
plastin 1
chr6_-_47361921 2.892 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr2_-_216586488 2.888 NM_018000
MREG
melanoregulin
chr10_+_8136778 2.831 GATA3
GATA binding protein 3
chr2_-_208342296 2.813 NM_003468
FZD5
frizzled homolog 5 (Drosophila)
chr18_+_54013575 2.805 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr11_+_129534983 2.770 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr1_+_27062215 2.762 NM_006142
SFN
stratifin
chr17_-_36996611 2.748 NM_000526
KRT14
keratin 14
chr1_+_199130571 2.710 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr17_+_7883076 2.676 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr17_+_71229151 2.661 ITGB4
integrin, beta 4
chr3_-_31998241 2.649 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr8_-_145609737 2.643 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr2_-_165186232 2.642 GRB14
growth factor receptor-bound protein 14
chr6_+_36206239 2.638 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr2_+_17585287 2.635 NM_003385
VSNL1
visinin-like 1
chr6_-_136913235 2.634 MAP7
microtubule-associated protein 7
chr12_-_51200347 2.618 NM_000424
KRT5
keratin 5
chr2_+_17585462 2.607 VSNL1
visinin-like 1
chr9_-_111300350 2.605 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr5_+_76150637 2.602 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr9_-_109291130 2.560 KLF4
Kruppel-like factor 4 (gut)
chr7_+_143683365 2.537 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr2_-_165186064 2.535 GRB14
growth factor receptor-bound protein 14
chr19_-_56215084 2.500 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr22_+_29122932 2.500 NM_012429
NM_033382
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr12_-_32940931 2.495 NM_001005242
NM_004572
PKP2

plakophilin 2

chr17_+_71229191 2.474 ITGB4
integrin, beta 4
chr12_+_6179736 2.432 NM_001769
CD9
CD9 molecule
chr9_-_111122826 2.428 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr2_+_64534774 2.423 NM_014181
HSPC159
galectin-related protein
chr6_+_31891293 2.411 HSPA1A
heat shock 70kDa protein 1A
chr19_+_40431678 2.405 LSR
lipolysis stimulated lipoprotein receptor
chr17_+_36642240 2.403 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr15_-_73818013 2.403


chr12_-_109424260 2.400 NM_016226
NM_057180
VPS29

vacuolar protein sorting 29 homolog (S. cerevisiae)

chr6_-_47385470 2.371 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr12_+_56271259 2.369 PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr17_-_37181636 2.349 JUP
junction plakoglobin
chr3_+_50167424 2.336 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_-_152155827 2.311 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr11_-_107234702 2.293 SLC35F2
solute carrier family 35, member F2
chr18_+_59295123 2.292 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr12_-_51585004 2.277 NM_002273
KRT8
keratin 8
chr6_+_31891509 2.271 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr17_-_7434113 2.268 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr11_+_129534922 2.266 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr11_-_119513948 2.264 TRIM29
tripartite motif containing 29
chr2_+_218992053 2.256 NM_007127
VIL1
villin 1
chr12_+_56271181 2.252 NM_001146258
NM_001146259
NM_001146260
NM_024779
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr9_+_33785558 2.239 NM_002771
PRSS3
protease, serine, 3
chr1_-_199635057 2.203 LAD1
ladinin 1
chr19_-_12747421 2.201 NM_001100176
NM_013312
HOOK2

hook homolog 2 (Drosophila)

chr1_-_151855413 2.194 NM_020672
S100A14
S100 calcium binding protein A14
chrX_+_105856531 2.187 NM_194463
RNF128
ring finger protein 128
chr3_+_4996141 2.171 BHLHE40
basic helix-loop-helix family, member e40
chr3_+_4996096 2.164 NM_003670
BHLHE40
basic helix-loop-helix family, member e40
chr6_+_125517033 2.160 NM_001003395
TPD52L1
tumor protein D52-like 1
chr4_+_74953971 2.159 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr1_-_58815753 2.149 NM_002353
TACSTD2
tumor-associated calcium signal transducer 2
chr11_+_696103 2.136 NM_022772
EPS8L2
EPS8-like 2
chr5_-_1935764 2.116 NM_016358
IRX4
iroquois homeobox 4
chr20_-_6052056 2.104 NM_017671
FERMT1
fermitin family member 1
chr2_-_219826854 2.079 NM_006000
TUBA4A
tubulin, alpha 4a
chr6_-_47385605 2.073 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr2_-_162883062 2.066 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr16_+_55156461 2.039 NM_032935
MT4
metallothionein 4
chr19_+_40298571 1.994 NM_001136007
NM_001136008
NM_001136009
NM_001136010
NM_001136011
NM_001136012
NM_005971
NM_021910
FXYD3







FXYD domain containing ion transport regulator 3







chr11_-_70837019 1.983 DHCR7
7-dehydrocholesterol reductase
chr12_-_46585032 1.970 NM_000376
NM_001017535
VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

chr8_-_110726201 1.967 NM_001099753
NM_001099754
NM_001099755
SYBU


syntabulin (syntaxin-interacting)


chr1_+_109594163 1.935 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr2_-_20288108 1.934 NM_002997
SDC1
syndecan 1
chr9_+_33740463 1.922 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chr2_-_20288647 1.903 NM_001006946
SDC1
syndecan 1
chr19_-_56147971 1.896 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr6_+_37245860 1.891 NM_002648
PIM1
pim-1 oncogene
chr4_+_128922852 1.890 NM_014278
HSPA4L
heat shock 70kDa protein 4-like
chr4_-_152156314 1.888 NM_006726
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr20_+_309675 1.888 TRIB3
tribbles homolog 3 (Drosophila)
chr13_+_27092846 1.883 POLR1D
polymerase (RNA) I polypeptide D, 16kDa
chr9_+_35663852 1.881 NM_001216
CA9
carbonic anhydrase IX
chr7_-_72761367 1.873 STX1A
syntaxin 1A (brain)
chr6_+_30958672 1.871 DDR1
discoidin domain receptor tyrosine kinase 1
chr1_-_151630168 1.870 NM_002964
S100A8
S100 calcium binding protein A8
chr11_-_124831391 1.865 FEZ1
fasciculation and elongation protein zeta 1 (zygin I)
chrX_-_99873728 1.859 NM_001129896
SYTL4
synaptotagmin-like 4
chr10_-_134940315 1.850 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr8_+_32525269 1.848 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr12_-_51253875 1.843 NM_175053
KRT74
keratin 74
chr14_+_58725104 1.842 NM_014992
DAAM1
dishevelled associated activator of morphogenesis 1
chr11_-_87710553 1.837 NM_001114173
NM_001814
NM_148170
CTSC


cathepsin C


chr6_+_33280396 1.836 NM_014234
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8
chr20_+_43468046 1.825 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr10_-_118754549 1.823 KIAA1598
KIAA1598
chr6_+_7486836 1.821 DSP
desmoplakin
chr3_+_190990142 1.821 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr6_+_7486862 1.819 NM_001008844
NM_004415
DSP

desmoplakin

chr20_-_10602429 1.818 NM_000214
JAG1
jagged 1
chr1_-_159257595 1.812 NM_016946
F11R
F11 receptor
chr5_-_176763991 1.808 F12
coagulation factor XII (Hageman factor)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.52 1.04e-02 GO:0008202 steroid metabolic process
1.37 4.36e-02 GO:0071702 organic substance transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 1.51e-06 GO:0044459 plasma membrane part
1.15 2.95e-06 GO:0005886 plasma membrane
1.14 9.62e-06 GO:0071944 cell periphery
1.09 8.70e-03 GO:0044425 membrane part
1.07 1.26e-02 GO:0016020 membrane
1.29 3.32e-02 GO:0030054 cell junction
1.43 4.90e-02 GO:0016323 basolateral plasma membrane

Nothing significant found in function category.