Motif ID: MSX1,2.p2

Z-value: 1.636


Transcription factors associated with MSX1,2.p2:

Gene SymbolEntrez IDGene Name
MSX1 4487 msh homeobox 1
MSX2 4488 msh homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MSX1chr4_+_49122720.801.7e-04Click!
MSX2chr5_+_174084137-0.401.3e-01Click!


Activity profile for motif MSX1,2.p2.

activity profile for motif MSX1,2.p2


Sorted Z-values histogram for motif MSX1,2.p2

Sorted Z-values for motif MSX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MSX1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_115880372 9.880 AMBP
alpha-1-microglobulin/bikunin precursor
chr10_+_7785360 8.314 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785331 7.749 ITIH2
inter-alpha (globulin) inhibitor H2
chr9_-_115880425 6.514 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_115880281 6.375 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_89115862 5.506 SPP1
secreted phosphoprotein 1
chr4_+_89115825 5.290 NM_000582
NM_001040058
NM_001040060
SPP1


secreted phosphoprotein 1


chrX_+_115481774 5.107 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr4_+_89115892 4.935 SPP1
secreted phosphoprotein 1
chr3_-_150422474 4.189 NM_000096
CP
ceruloplasmin (ferroxidase)
chr4_+_71096830 4.168 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr14_-_64479198 4.086 NM_002083
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr10_+_7785347 4.011 ITIH2
inter-alpha (globulin) inhibitor H2
chr1_-_145163520 3.590 FMO5
flavin containing monooxygenase 5
chr10_+_7785290 3.405 ITIH2
inter-alpha (globulin) inhibitor H2
chr9_-_115880366 3.296 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_89115923 3.101 SPP1
secreted phosphoprotein 1
chr4_+_155703581 2.880 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr17_-_61655915 2.856 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr12_+_7039453 2.534


chr16_-_29817841 2.363 NM_001114099
NM_001114100
NM_012410
NM_201575
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr3_+_52803823 2.327 NM_002217
ITIH3
inter-alpha (globulin) inhibitor H3
chr1_-_108032645 2.179 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr11_-_114593838 2.164 CADM1
cell adhesion molecule 1
chr4_-_155753332 1.776 NM_000509
NM_021870
FGG

fibrinogen gamma chain

chr10_+_7785235 1.642 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr9_-_115880494 1.496 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr12_+_49605010 1.493 METTL7A
methyltransferase like 7A
chr6_+_88026338 1.433 ZNF292
zinc finger protein 292
chr3_-_150578148 1.392 TM4SF1
transmembrane 4 L six family member 1
chr13_-_45577144 1.283 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr1_+_200246370 1.270 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr7_+_94377145 1.164 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr3_-_150578207 1.161 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr12_+_70119785 1.146 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr5_+_59819761 1.122 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr12_-_69837831 1.089 TSPAN8
tetraspanin 8
chr14_-_94669547 1.081 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr16_+_55042924 1.027 NM_018233
OGFOD1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr8_-_145613034 1.010 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr8_-_145613058 0.976 NM_130849
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr3_-_101316038 0.915 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr3_-_121884091 0.904 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr7_+_111850367 0.887 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr5_-_42847716 0.877 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr16_+_55042936 0.862 OGFOD1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr16_+_80626402 0.808 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr3_-_150578023 0.794 TM4SF1
transmembrane 4 L six family member 1
chr16_+_80626459 0.749 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr11_+_7574992 0.745 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chrX_+_128966844 0.741 NM_021946
BCORL1
BCL6 corepressor-like 1
chr16_+_80626456 0.735 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr4_-_186970366 0.707 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr3_-_121883647 0.686 HGD
homogentisate 1,2-dioxygenase
chr1_+_205344200 0.682 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr9_+_130942029 0.677 PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr2_+_138438277 0.668 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr2_-_162638174 0.658 DPP4
dipeptidyl-peptidase 4
chr1_-_19089971 0.625 NM_001161504
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr4_-_89963177 0.620 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr2_+_162908828 0.616 NM_012198
GCA
grancalcin, EF-hand calcium binding protein
chr6_-_31938572 0.604 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr3_+_189425886 0.602 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_165564904 0.595 NM_001198783
POU2F1
POU class 2 homeobox 1
chr17_+_38306339 0.563 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr12_+_887272 0.559 WNK1
WNK lysine deficient protein kinase 1
chr10_+_114123828 0.559 NM_203379
ACSL5
acyl-CoA synthetase long-chain family member 5
chr14_-_104330982 0.558 NM_005163
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr22_+_33792125 0.556 NM_001008494
ISX
intestine-specific homeobox
chr3_+_12367993 0.547 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr3_-_150578103 0.544 TM4SF1
transmembrane 4 L six family member 1
chr5_+_139856688 0.543 ANKHD1
ankyrin repeat and KH domain containing 1
chr1_+_54132447 0.542 NM_000792
NM_001039715
NM_001039716
NM_213593
DIO1



deiodinase, iodothyronine, type I



chr8_-_38127489 0.542 NM_000349
STAR
steroidogenic acute regulatory protein
chr20_+_31613800 0.520 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr17_+_67628749 0.517 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr17_+_67628763 0.483 SOX9
SRY (sex determining region Y)-box 9
chr3_+_46591048 0.464 NM_001174136
TDGF1
teratocarcinoma-derived growth factor 1
chr9_+_133295297 0.464 NM_013318
PRRC2B
proline-rich coiled-coil 2B
chrX_-_100920493 0.463 GK
glycerol kinase
chr16_-_21197072 0.449 CRYM
crystallin, mu
chr7_+_120415958 0.412 NM_024913
C7orf58
chromosome 7 open reading frame 58
chr1_-_85816520 0.399 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr6_-_26038817 0.390 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr6_+_163904564 0.382 QKI
quaking homolog, KH domain RNA binding (mouse)
chr22_+_34109095 0.373 HMOX1
heme oxygenase (decycling) 1
chr5_+_126887056 0.355 PRRC1
proline-rich coiled-coil 1
chr6_-_31215089 0.329 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr17_+_4795128 0.322 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr1_+_200246312 0.319 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr21_-_31995972 0.317 SCAF4
SR-related CTD-associated factor 4
chr20_-_48686832 0.310 NM_080829
FAM65C
family with sequence similarity 65, member C
chr7_+_120416680 0.302 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr16_+_52037186 0.281 RBL2
retinoblastoma-like 2 (p130)
chr10_-_44794146 0.281 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr12_-_110410730 0.279 ATXN2
ataxin 2
chr20_+_42644633 0.275 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chrX_-_74292800 0.273 NM_004299
ABCB7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr11_-_128567302 0.271 NM_001142685
ARHGAP32
Rho GTPase activating protein 32
chr1_+_110361634 0.268 AHCYL1
adenosylhomocysteinase-like 1
chr2_-_165133239 0.258 GRB14
growth factor receptor-bound protein 14
chr11_-_72141064 0.258 NM_001040118
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr12_-_9252227 0.240 NM_002864
PZP
pregnancy-zone protein
chr6_-_150109324 0.219 NM_198887
NUP43
nucleoporin 43kDa
chrX_+_153310171 0.217 NM_001183
ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr1_-_245120900 0.214 AHCTF1
AT hook containing transcription factor 1
chr17_+_7683958 0.212 NM_001080424
KDM6B
lysine (K)-specific demethylase 6B
chrX_-_76824726 0.210 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr19_-_17236522 0.209 NM_031941
USHBP1
Usher syndrome 1C binding protein 1
chr16_-_55042614 0.209 NM_007006
NUDT21
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr2_-_96238234 0.203 STARD7
StAR-related lipid transfer (START) domain containing 7
chr1_-_188713324 0.203 NM_199051
FAM5C
family with sequence similarity 5, member C
chr1_+_165565006 0.191 POU2F1
POU class 2 homeobox 1
chr12_+_84792203 0.187 NM_006183
NTS
neurotensin
chr1_+_151498802 0.171 NM_000427
LOR
loricrin
chr17_-_4831644 0.169 NM_001171166
NM_015099
CAMTA2

calmodulin binding transcription activator 2

chr4_-_66218777 0.165 EPHA5
EPH receptor A5
chr17_+_46176105 0.164 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr19_-_48771449 0.163 XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr7_+_21434818 0.156


chr11_+_101488380 0.156 NM_001195045
YAP1
Yes-associated protein 1
chr17_-_45196465 0.156 FAM117A
family with sequence similarity 117, member A
chr10_+_28918672 0.154 WAC
WW domain containing adaptor with coiled-coil
chr7_+_120416103 0.149 C7orf58
chromosome 7 open reading frame 58
chr14_-_91046383 0.147 NM_032560
SMEK1
SMEK homolog 1, suppressor of mek1 (Dictyostelium)
chr2_-_183095308 0.145 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr21_+_39117064 0.144 ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr10_+_49279647 0.144 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr16_-_11918019 0.144 NM_001130007
GSPT1
G1 to S phase transition 1
chr4_-_77176163 0.138 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr1_+_110683580 0.137 RBM15
RNA binding motif protein 15
chr5_-_160211623 0.136 NM_025153
ATP10B
ATPase, class V, type 10B
chrX_+_153310219 0.133 ATP6AP1
ATPase, H+ transporting, lysosomal accessory protein 1
chr17_-_4831388 0.131 NM_001171167
NM_001171168
CAMTA2

calmodulin binding transcription activator 2

chr16_-_70685715 0.127 NM_001142318
TXNL4B
thioredoxin-like 4B
chr6_+_33365445 0.126 PFDN6
prefoldin subunit 6
chrX_-_110542040 0.126 NM_178151
NM_001195553
NM_178152
NM_178153
DCX



doublecortin



chrX_-_19898302 0.125 NM_198279
CXorf23
chromosome X open reading frame 23
chr6_+_64289585 0.125 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr5_-_178977441 0.124 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr7_-_99555399 0.123 NM_001190415
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr4_+_114190233 0.120 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr19_+_45564549 0.115 PLD3
phospholipase D family, member 3
chrX_+_16578201 0.114 NM_004057
S100G
S100 calcium binding protein G
chr19_-_6621078 0.114 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr5_+_109053034 0.112 NM_002372
MAN2A1
mannosidase, alpha, class 2A, member 1
chr9_+_135491305 0.111 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr3_+_9919511 0.110 NM_001193380
NM_153480
IL17RE

interleukin 17 receptor E

chr10_-_64698831 0.109 NM_004241
JMJD1C
jumonji domain containing 1C
chr6_-_119512035 0.104 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr12_-_6354818 0.091 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chrX_+_123062143 0.089 STAG2
stromal antigen 2
chrX_-_48713194 0.089 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr5_-_138238891 0.089 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr4_-_89424691 0.089 PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr2_+_170742900 0.088 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr12_-_51457371 0.088 NM_015848
KRT76
keratin 76
chr8_+_67096344 0.085 NM_033105
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr8_+_75899326 0.085 NM_015886
PI15
peptidase inhibitor 15
chr7_+_38984133 0.084 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr1_+_118273887 0.082 NM_006784
WDR3
WD repeat domain 3
chr1_-_156923111 0.081 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr11_-_6597237 0.080 NM_000391
TPP1
tripeptidyl peptidase I
chr16_-_65838899 0.080 NM_013241
FHOD1
formin homology 2 domain containing 1
chr21_-_36774257 0.080 NM_001146079
NM_144492
CLDN14

claudin 14

chr6_-_123999640 0.078 NM_006073
TRDN
triadin
chr1_+_36545283 0.074 NM_024676
SH3D21
SH3 domain containing 21
chrX_-_24600661 0.072 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr5_+_176726918 0.072 RGS14
regulator of G-protein signaling 14
chr6_-_30633349 0.071 NM_005275
GNL1
guanine nucleotide binding protein-like 1
chr1_+_22852268 0.067 NM_000491
C1QB
complement component 1, q subcomponent, B chain
chr3_-_11660395 0.061 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr4_+_71330797 0.060 NM_001145006
MUC7
mucin 7, secreted
chr17_-_9870292 0.059 NM_001130831
GAS7
growth arrest-specific 7
chr2_+_98070026 0.058 NM_144992
VWA3B
von Willebrand factor A domain containing 3B
chr19_+_53016910 0.055 NM_000554
CRX
cone-rod homeobox
chr9_+_134843918 0.054 NM_001135031
NM_004188
GFI1B

growth factor independent 1B transcription repressor

chr12_-_14024187 0.051 NM_000834
GRIN2B
glutamate receptor, ionotropic, N-methyl D-aspartate 2B
chr11_+_91724909 0.048 NM_001008781
FAT3
FAT tumor suppressor homolog 3 (Drosophila)
chr7_+_80145461 0.048 CD36
CD36 molecule (thrombospondin receptor)
chr11_-_6597220 0.047 TPP1
tripeptidyl peptidase I
chr13_+_51496679 0.046 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chrX_+_30171768 0.045 NM_002363
NM_177415
MAGEB1

melanoma antigen family B, 1

chr5_-_148738980 0.043 NM_014443
IL17B
interleukin 17B
chr5_-_138238953 0.040 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr4_+_148757958 0.039 NM_018241
TMEM184C
transmembrane protein 184C
chr9_-_85773899 0.036 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr7_+_106292932 0.036 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr17_-_10217046 0.035 NM_003802
MYH13
myosin, heavy chain 13, skeletal muscle
chr3_-_139333813 0.034 NM_016161
A4GNT
alpha-1,4-N-acetylglucosaminyltransferase
chrX_+_99726445 0.034 NM_022144
TNMD
tenomodulin
chr11_-_8636958 0.033 NM_014818
TRIM66
tripartite motif containing 66
chr19_+_54068373 0.032 PPP1R15A
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr5_-_59819642 0.026 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_55460451 0.026 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr1_-_27825633 0.026 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr7_-_126670804 0.025 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr11_-_8789457 0.025 NM_139157
ST5
suppression of tumorigenicity 5
chr5_+_68703036 0.024 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr8_+_107807415 0.023 NM_001198534
NM_001198535
OXR1

oxidation resistance 1


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.