Motif ID: PAX6.p2

Z-value: 0.301


Transcription factors associated with PAX6.p2:

Gene SymbolEntrez IDGene Name
PAX6 5080 paired box 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX6chr11_-_31782169,
chr11_-_31789360,
chr11_-_31789168,
chr11_-_31796061,
chr11_-_31789334
0.361.7e-01Click!


Activity profile for motif PAX6.p2.

activity profile for motif PAX6.p2


Sorted Z-values histogram for motif PAX6.p2

Sorted Z-values for motif PAX6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX6.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_123925343 0.599 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1(Drosophila)


chr15_+_49760841 0.415 NM_001165257
NM_013243
SCG3

secretogranin III

chr18_+_59571256 0.295 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_165565006 0.271 POU2F1
POU class 2 homeobox 1
chr1_+_165564904 0.251 NM_001198783
POU2F1
POU class 2 homeobox 1
chrX_+_52797004 0.202 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chrX_-_52700674 0.188 NM_173358
SSX7
synovial sarcoma, X breakpoint 7
chrX_+_48127911 0.185 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chr6_+_101953389 0.134 GRIK2
glutamate receptor, ionotropic, kainate 2
chr11_-_11331411 0.127 CSNK2A1P
casein kinase 2, alpha 1 polypeptide pseudogene
chr12_-_131725848 0.113 POLE
polymerase (DNA directed), epsilon
chrX_-_106336199 0.110 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr5_-_135259403 0.109 NM_000590
IL9
interleukin 9
chrX_-_13745134 0.105 GPM6B
glycoprotein M6B
chr12_-_69317441 0.098 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr5_-_141318810 0.097 NM_016580
PCDH12
protocadherin 12
chrX_-_53478016 0.095 NM_001037811
NM_004493
HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10

chr12_+_67366989 0.092 NM_020401
NUP107
nucleoporin 107kDa
chr5_-_98290117 0.090 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr6_-_10520592 0.088 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr6_-_64087806 0.087 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr8_-_102029997 0.085 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_+_51855343 0.083 OSBPL9
oxysterol binding protein-like 9
chr19_+_15920817 0.080 NM_001004465
OR10H4
olfactory receptor, family 10, subfamily H, member 4
chr11_+_117452995 0.080 TMPRSS4
transmembrane protease, serine 4
chr1_+_35623688 0.069 ZMYM4
zinc finger, MYM-type 4
chr4_-_26100986 0.068 NM_000730
CCKAR
cholecystokinin A receptor
chr21_+_38550739 0.066 NM_170736
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr6_+_152168500 0.063 NM_001122741
ESR1
estrogen receptor 1
chrX_-_48156287 0.062 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chr2_-_200033445 0.060 SATB2
SATB homeobox 2
chr7_+_154943466 0.059 NM_001427
EN2
engrailed homeobox 2
chr11_-_28086277 0.057 NM_031217
KIF18A
kinesin family member 18A
chrX_-_135783496 0.057


chr7_-_26198673 0.055 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr17_-_1195096 0.055 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr3_-_120861959 0.055 NM_022135
POPDC2
popeye domain containing 2
chr1_+_51855133 0.053 NM_024586
NM_148906
NM_148908
NM_148909
OSBPL9



oxysterol binding protein-like 9



chr1_-_12830728 0.053 NM_001146181
HNRNPCL1
LOC649330
heterogeneous nuclear ribonucleoprotein C-like 1
heterogeneous nuclear ribonucleoprotein C-like
chr6_+_155579788 0.051 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr7_-_72761367 0.049 STX1A
syntaxin 1A (brain)
chr6_-_31954795 0.049 NM_001178044
NM_025257
SLC44A4

solute carrier family 44, member 4

chrX_-_15242589 0.048 NM_001012428
ASB11
ankyrin repeat and SOCS box containing 11
chr19_+_59941785 0.046 NM_015868
KIR2DS2
KIR2DL3
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
chr17_-_36276987 0.044 NM_000223
KRT12
keratin 12
chr5_-_58918031 0.044 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr22_+_38652555 0.041 GRAP2
GRB2-related adaptor protein 2
chr1_+_87153025 0.039 HS2ST1
heparan sulfate 2-O-sulfotransferase 1
chr4_+_187385618 0.038 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr3_+_138132006 0.038 NM_001190796
NCK1
NCK adaptor protein 1
chr6_+_101953581 0.036 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr6_-_74284522 0.036 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr8_+_18123456 0.034 NM_001160174
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr9_+_130485754 0.034 NM_001122821
SET
SET nuclear oncogene
chr4_+_70896236 0.034 NM_001009181
NM_003154
STATH

statherin

chr9_-_94206648 0.033 NM_014057
NM_033014
OGN

osteoglycin

chr5_-_169657312 0.032 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chrX_-_65176564 0.031 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr3_-_15538164 0.031 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr3_+_153499883 0.031 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr11_+_14883118 0.031 CALCB
calcitonin-related polypeptide beta
chr8_-_87824996 0.031 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr15_+_27001131 0.030 NM_001130414
NM_005503
APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2

chr11_-_57054756 0.030 NM_012456
TIMM10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr15_-_23204887 0.030 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr10_+_118340460 0.029 NM_006229
PNLIPRP1
pancreatic lipase-related protein 1
chr13_+_52500830 0.027 NM_006418
OLFM4
olfactomedin 4
chr20_+_4650499 0.027 NM_012409
PRND
prion protein 2 (dublet)
chr4_-_91979113 0.025 NM_183049
TMSL3
thymosin-like 3
chr19_+_54299686 0.025 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr20_-_45360903 0.024 ZMYND8
zinc finger, MYND-type containing 8
chr21_+_38566298 0.023 NM_170737
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr2_-_138762909 0.023


chr16_-_11282595 0.023 NM_002761
PRM1
protamine 1
chr8_+_21972804 0.022 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr1_-_108588186 0.022 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chr10_+_129735796 0.022 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chr1_+_145841569 0.022 NM_005267
GJA8
gap junction protein, alpha 8, 50kDa
chr18_+_17076166 0.021 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr3_-_196792059 0.021 APOD
apolipoprotein D
chr17_-_36294962 0.020 NM_019010
KRT20
keratin 20
chrX_-_13745234 0.018 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr14_-_30927931 0.018 NM_015473
HEATR5A
HEAT repeat containing 5A
chr13_+_96726415 0.017 MBNL2
muscleblind-like 2 (Drosophila)
chr14_+_101345878 0.017 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr21_-_30510113 0.016 NM_199328
CLDN8
claudin 8
chr6_-_155818728 0.015 NM_015718
NOX3
NADPH oxidase 3
chr16_+_68705029 0.014 NM_017990
PDPR
pyruvate dehydrogenase phosphatase regulatory subunit
chr19_+_15713200 0.014 NM_013938
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr15_-_48192804 0.014 ATP8B4
ATPase, class I, type 8B, member 4
chr12_+_10351683 0.013 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr12_-_43556220 0.013 NELL2
NEL-like 2 (chicken)
chr12_-_18134319 0.012 NM_024730
RERGL
RERG/RAS-like
chr3_-_109730858 0.012 NM_014981
MYH15
myosin, heavy chain 15
chr6_-_42270671 0.012 NM_002098
GUCA1B
guanylate cyclase activator 1B (retina)
chr8_-_21827057 0.010 NM_003974
DOK2
docking protein 2, 56kDa
chr14_+_28311740 0.010 C14orf23
chromosome 14 open reading frame 23
chr13_+_23742846 0.009 SPATA13
spermatogenesis associated 13
chr11_+_28086373 0.008 NM_001113528
NM_152636
METTL15

methyltransferase like 15

chrX_+_49718954 0.008 NM_000084
CLCN5
chloride channel 5
chr2_-_199922047 0.008 SATB2
SATB homeobox 2
chrX_+_144716619 0.008 NM_004709
CXorf1
chromosome X open reading frame 1
chr4_+_71298187 0.008 NM_021225
PROL1
proline rich, lacrimal 1
chr12_+_119224506 0.007 NM_012240
SIRT4
sirtuin 4
chr12_+_18305740 0.007 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chrX_-_6156655 0.007 NM_181332
NLGN4X
neuroligin 4, X-linked
chr2_-_171631728 0.007 NM_001136555
TLK1
tousled-like kinase 1
chr4_+_71261066 0.004 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr20_-_32877029 0.003 NM_014071
NCOA6
nuclear receptor coactivator 6
chr10_+_102212787 0.003 NM_003393
WNT8B
wingless-type MMTV integration site family, member 8B
chr2_+_108571209 0.003 LIMS1
LIM and senescent cell antigen-like domains 1
chr11_+_76561471 0.002 MYO7A
myosin VIIA
chr12_-_43555607 0.002 NM_001145109
NELL2
NEL-like 2 (chicken)
chr1_-_85946676 0.002 NM_001170670
NM_017953
ZNHIT6

zinc finger, HIT-type containing 6

chr8_-_59575249 0.002 NM_000780
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr16_-_71650034 0.001 NM_001164766
ZFHX3
zinc finger homeobox 3
chr11_-_117253354 0.000 NM_001164831
FXYD6
FXYD domain containing ion transport regulator 6
chrX_-_13744933 0.000 GPM6B
glycoprotein M6B
chr7_+_45033757 0.000 NM_001029835
CCM2
cerebral cavernous malformation 2
chr5_+_180399830 0.000 NM_152547
BTNL9
butyrophilin-like 9
chr19_+_56990222 0.000 NM_002030
FPR3
formyl peptide receptor 3

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.