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Motif ID: PAX5.p2

Z-value: 1.079

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_+_43399101	2.947		MAOA	monoamine oxidase A
chr2_-_98713862	2.026		MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr8_+_136538739	1.568	NM_006558	KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr3_-_151171190	1.561	NM_002628 NM_053024	PFN2	profilin 2
chr20_-_23566325	1.471	NM_000099	CST3	cystatin C
chr2_+_235525355	1.464	NM_014521	SH3BP4	SH3-domain binding protein 4
chr13_+_26029879	1.401		WASF3	WAS protein family, member 3
chr21_+_17807167	1.339	NM_001338	CXADR	coxsackie virus and adenovirus receptor
chr2_-_20288647	1.279	NM_001006946	SDC1	syndecan 1
chr8_+_26427378	1.197	NM_001197293	DPYSL2	dihydropyrimidinase-like 2
chr3_-_151171576	1.184		PFN2	profilin 2
chr2_-_98714020	1.165	NM_012214	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr11_+_120828058	1.152	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr1_-_233879617	1.145	NM_001098722	GNG4	guanine nucleotide binding protein (G protein), gamma 4
chr12_-_105165805	1.121	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr14_-_104515738	1.104	NM_138420	AHNAK2	AHNAK nucleoprotein 2
chr2_-_20288108	1.079	NM_002997	SDC1	syndecan 1
chr15_+_99237527	1.047	NM_000693	ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr12_-_13044467	1.011	NM_015987	HEBP1	heme binding protein 1
chr21_-_45118037	0.999	NM_004339	PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr15_-_50375143	0.998	NM_018728	MYO5C	myosin VC
chr10_+_124124083	0.977	NM_001001974	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr12_-_13044314	0.969		HEBP1	heme binding protein 1
chr5_+_17270474	0.961	NM_006317	BASP1	brain abundant, membrane attached signal protein 1
chr20_+_336941	0.957		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chrX_-_132947141	0.945		GPC3	glypican 3
chr22_-_44015424	0.934		KIAA0930	KIAA0930
chr13_+_26029799	0.925	NM_006646	WASF3	WAS protein family, member 3
chr9_-_36391149	0.925	NM_194330	RNF38	ring finger protein 38
chr10_+_124124196	0.918		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr5_+_17270781	0.918		BASP1	brain abundant, membrane attached signal protein 1
chrX_-_132947290	0.898	NM_001164617 NM_001164618 NM_001164619 NM_004484	GPC3	glypican 3
chr10_-_30064600	0.885	NM_003174	SVIL	supervillin
chr9_+_494661	0.869	NM_015158	KANK1	KN motif and ankyrin repeat domains 1
chr10_+_131155443	0.859	NM_002412	MGMT	O-6-methylguanine-DNA methyltransferase
chr10_+_131155490	0.854		MGMT	O-6-methylguanine-DNA methyltransferase
chr15_+_97009194	0.843		IGF1R	insulin-like growth factor 1 receptor
chr20_-_49818306	0.816	NM_006045	ATP9A	ATPase, class II, type 9A
chr1_+_43769065	0.812	NM_002840 NM_130440	PTPRF	protein tyrosine phosphatase, receptor type, F
chr6_-_138470160	0.810	NM_022121	PERP	PERP, TP53 apoptosis effector
chr14_-_94855848	0.804	NM_024734	CLMN	calmin (calponin-like, transmembrane)
chr20_-_49818268	0.803		ATP9A	ATPase, class II, type 9A
chr21_-_45117989	0.799		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr5_+_135392482	0.784	NM_000358	TGFBI	transforming growth factor, beta-induced, 68kDa
chr13_-_105985313	0.770	NM_004093	EFNB2	ephrin-B2
chr1_-_223907283	0.757	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr21_-_45118026	0.756		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr16_-_66827449	0.755	NM_024939	ESRP2	epithelial splicing regulatory protein 2
chr20_+_336963	0.754		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr16_-_11588525	0.746		LITAF	lipopolysaccharide-induced TNF factor
chr10_-_15250616	0.739	NM_004808	NMT2	N-myristoyltransferase 2
chr18_+_53862888	0.714		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr12_-_74711642	0.713	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr14_-_52487386	0.710		FERMT2	fermitin family member 2
chr16_-_87450734	0.709		GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase
chr1_-_11637325	0.703	NM_012168	FBXO2	F-box protein 2
chr2_-_20075889	0.700		MATN3	matrilin 3
chrX_+_17665483	0.698	NM_001037535 NM_001037536 NM_001037540 NM_006746	SCML1	sex comb on midleg-like 1 (Drosophila)
chr7_-_107883929	0.688	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr21_-_45117960	0.686		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr17_-_78199384	0.684	NM_019613	WDR45L	WDR45-like
chr2_-_101134146	0.683	NM_001102426	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr21_+_45649429	0.680	NM_130445	COL18A1	collagen, type XVIII, alpha 1
chr6_+_29963328	0.675		HLA-H	major histocompatibility complex, class I, H (pseudogene)
chr9_-_36390817	0.671	NM_194328 NM_194332	RNF38	ring finger protein 38
chr19_-_242335	0.664	NM_003712 NM_177526	PPAP2C	phosphatidic acid phosphatase type 2C
chr10_-_126839000	0.658		CTBP2	C-terminal binding protein 2
chr12_-_74711474	0.657		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr18_+_53862744	0.657		NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr3_+_173240983	0.656	NM_001135095	FNDC3B	fibronectin type III domain containing 3B
chr1_-_11637058	0.652		FBXO2	F-box protein 2
chr22_-_44015248	0.649	NM_001009880	KIAA0930	KIAA0930
chr11_-_86343859	0.647	NM_012193	FZD4	frizzled homolog 4 (Drosophila)
chr16_-_11588257	0.644	NM_001136472 NM_001136473	LITAF	lipopolysaccharide-induced TNF factor
chr20_-_43410437	0.642	NM_002999	SDC4	syndecan 4
chr10_-_126839056	0.639	NM_001329	CTBP2	C-terminal binding protein 2
chr14_-_52487558	0.634	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chr6_+_83130673	0.632	NM_001166392	TPBG	trophoblast glycoprotein
chr8_-_17702665	0.626	NM_001001924 NM_001001925	MTUS1	microtubule associated tumor suppressor 1
chr17_-_15407497	0.619	NM_001135036 NM_145301	FAM18B2-CDRT4 FAM18B2	FAM18B2-CDRT4 read-through transcript family with sequence similarity 18, member B2
chr4_-_102487649	0.618	NM_000944 NM_001130691 NM_001130692	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr1_-_9807136	0.617	NM_001009566 NM_014944	CLSTN1	calsyntenin 1
chr1_-_9806611	0.615		CLSTN1	calsyntenin 1
chr20_+_336717	0.614		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr21_+_41461962	0.604		BACE2	beta-site APP-cleaving enzyme 2
chr20_-_17610704	0.595		RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chr3_-_133923906	0.593	NM_153240	NPHP3	nephronophthisis 3 (adolescent)
chr11_-_11987198	0.592	NM_015881	DKK3	dickkopf homolog 3 (Xenopus laevis)
chr18_-_46978029	0.584	NM_016626	MEX3C	mex-3 homolog C (C. elegans)
chr11_-_11987115	0.578		DKK3	dickkopf homolog 3 (Xenopus laevis)
chr15_-_88159061	0.577	NM_001150	ANPEP	alanyl (membrane) aminopeptidase
chr4_-_158111995	0.575	NM_016205	PDGFC	platelet derived growth factor C
chr18_+_54489798	0.570		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr6_-_3697244	0.568	NM_183373	C6orf145	chromosome 6 open reading frame 145
chr17_-_72218535	0.561	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr20_-_17610828	0.561	NM_001042576 NM_004587	RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chr1_-_22136263	0.561	NM_005529	HSPG2	heparan sulfate proteoglycan 2
chr20_-_55718351	0.560	NM_020182	PMEPA1	prostate transmembrane protein, androgen induced 1
chr22_-_35113923	0.554		MYH9	myosin, heavy chain 9, non-muscle
chr10_+_121475628	0.552		INPP5F	inositol polyphosphate-5-phosphatase F
chr4_-_7991992	0.547	NM_001134647 NM_198595	AFAP1	actin filament associated protein 1
chr21_+_41461597	0.543	NM_012105 NM_138991 NM_138992	BACE2	beta-site APP-cleaving enzyme 2
chr16_-_87450849	0.540	NM_000512	GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase
chr22_-_37062114	0.532		CSNK1E	casein kinase 1, epsilon
chr8_-_11763031	0.531		CTSB	cathepsin B
chr8_-_11763023	0.531		CTSB	cathepsin B
chr15_+_99237555	0.528		ALDH1A3	aldehyde dehydrogenase 1 family, member A3
chr1_-_233880676	0.525	NM_001098721 NM_004485	GNG4	guanine nucleotide binding protein (G protein), gamma 4
chr11_+_101485946	0.525	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr2_+_173000590	0.518		ITGA6	integrin, alpha 6
chr2_+_176761552	0.518	NM_024501	HOXD1	homeobox D1
chr2_+_9264360	0.516		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr22_-_35114001	0.511	NM_002473	MYH9	myosin, heavy chain 9, non-muscle
chr8_-_11762918	0.509		CTSB	cathepsin B
chr2_+_9264327	0.506	NM_001135191 NM_003887	ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr17_+_19492427	0.504	NM_000382 NM_001031806	ALDH3A2	aldehyde dehydrogenase 3 family, member A2
chr5_-_1577022	0.503	NM_024830	LPCAT1	lysophosphatidylcholine acyltransferase 1
chr21_+_45649719	0.500
chr2_-_216009015	0.496	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr19_+_3045528	0.495		GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr2_+_24126140	0.493		FKBP1B	FK506 binding protein 1B, 12.6 kDa
chr4_-_177950658	0.491	NM_005429	VEGFC	vascular endothelial growth factor C
chr18_+_54489763	0.491		MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1
chr2_-_235070431	0.490	NM_005737	ARL4C	ADP-ribosylation factor-like 4C
chr8_-_11763004	0.490		CTSB	cathepsin B
chr1_+_945331	0.490	NM_198576	AGRN	agrin
chr18_+_58341637	0.487	NM_017742	ZCCHC2	zinc finger, CCHC domain containing 2
chr18_+_53862386	0.487	NM_001144967 NM_015277	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr6_+_142664490	0.486	NM_001032394 NM_001032395 NM_020455 NM_198569	GPR126	G protein-coupled receptor 126
chr16_-_4528380	0.475	NM_001199054	C16orf5	chromosome 16 open reading frame 5
chr10_+_120853616	0.467		FAM45A FAM45B	family with sequence similarity 45, member A family with sequence similarity 45, member A pseudogene
chr4_+_6322506	0.466		WFS1	Wolfram syndrome 1 (wolframin)
chr3_+_57969127	0.464	NM_001164317 NM_001164318 NM_001164319 NM_001457	FLNB	filamin B, beta
chr1_-_11636983	0.464		FBXO2	F-box protein 2
chr5_+_52320660	0.464	NM_002203	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr6_+_138230045	0.461	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr6_+_29963485	0.459
chr2_-_20075929	0.455	NM_002381	MATN3	matrilin 3
chr9_+_111850698	0.454	NM_001004065 NM_001198656	AKAP2	A kinase (PRKA) anchor protein 2
chr2_-_20714303	0.451	NM_022460	HS1BP3	HCLS1 binding protein 3
chr1_-_93919789	0.450	NM_003567	BCAR3	breast cancer anti-estrogen resistance 3
chr11_+_129445057	0.450		APLP2	amyloid beta (A4) precursor-like protein 2
chr11_+_129444997	0.450		APLP2	amyloid beta (A4) precursor-like protein 2
chr7_+_45894480	0.440	NM_000596	IGFBP1	insulin-like growth factor binding protein 1
chr10_+_120853600	0.439	NM_207009	FAM45A	family with sequence similarity 45, member A
chr9_-_76892860	0.438	NM_001127603 NM_017881	C9orf95	chromosome 9 open reading frame 95
chr11_+_32068990	0.437	NM_002901	RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr17_+_45858606	0.434		ACSF2	acyl-CoA synthetase family member 2
chr1_+_9275518	0.434	NM_025106	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
chr10_+_121475583	0.434	NM_014937	INPP5F	inositol polyphosphate-5-phosphatase F
chr17_+_77779570	0.431	NM_001042422	SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr11_+_129444877	0.430	NM_001142276 NM_001142277 NM_001142278 NM_001642	APLP2	amyloid beta (A4) precursor-like protein 2
chr9_+_130354490	0.430	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr1_-_94475504	0.428		ARHGAP29	Rho GTPase activating protein 29
chr2_-_224612177	0.423	NM_001136528 NM_006216	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr2_+_238265519	0.422	NM_001137551 NM_001137552 NM_001137553 NM_004735	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chrX_-_152804731	0.422		L1CAM	L1 cell adhesion molecule
chr1_+_181259317	0.421
chr15_+_67239853	0.418	NM_015554	GLCE	glucuronic acid epimerase
chr6_-_10527772	0.417	NM_001042425	TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_-_94475840	0.417	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr19_-_18913032	0.415	NM_004838	HOMER3	homer homolog 3 (Drosophila)
chr3_-_31998241	0.413	NM_001174060 NM_017784	OSBPL10	oxysterol binding protein-like 10
chr3_-_126257425	0.413	NM_020733	HEG1	HEG homolog 1 (zebrafish)
chr19_-_18913011	0.413		HOMER3	homer homolog 3 (Drosophila)
chr17_+_45858517	0.412	NM_025149	ACSF2	acyl-CoA synthetase family member 2
chr3_-_31997738	0.411		OSBPL10	oxysterol binding protein-like 10
chr2_+_238265617	0.408		LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr7_+_55054416	0.408		EGFR	epidermal growth factor receptor
chr20_+_336693	0.408	NM_006462 NM_031229	RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr20_+_25176698	0.407	NM_002862	PYGB	phosphorylase, glycogen; brain
chr13_+_97593469	0.406		FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr16_-_4106186	0.406	NM_001116	ADCY9	adenylate cyclase 9
chr22_-_49292995	0.405	NM_033200	LMF2	lipase maturation factor 2
chr6_+_89847183	0.405		PNRC1	proline-rich nuclear receptor coactivator 1
chr12_+_130945215	0.405	NM_003565	ULK1	unc-51-like kinase 1 (C. elegans)
chr17_+_50697355	0.404		HLF	hepatic leukemia factor
chr2_-_165186232	0.402		GRB14	growth factor receptor-bound protein 14
chr22_-_49292886	0.401		LMF2	lipase maturation factor 2
chr19_+_13736345	0.401		MRI1	methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr11_+_129445017	0.400		APLP2	amyloid beta (A4) precursor-like protein 2
chr22_-_41375323	0.400	NM_000398	CYB5R3	cytochrome b5 reductase 3
chr16_-_55876099	0.399		PLLP	plasmolipin
chr11_+_118544625	0.399	NM_024618 NM_170722	NLRX1	NLR family member X1
chr17_+_50697319	0.398	NM_002126	HLF	hepatic leukemia factor
chr6_+_35418377	0.398		PPARD	peroxisome proliferator-activated receptor delta
chr8_+_86563382	0.395	NM_000067	CA2	carbonic anhydrase II
chr19_-_242168	0.393	NM_177543	PPAP2C	phosphatidic acid phosphatase type 2C
chr19_+_3045266	0.392	NM_002067	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr8_+_136539290	0.391		KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3
chr11_+_129445002	0.390		APLP2	amyloid beta (A4) precursor-like protein 2
chr6_-_134538526	0.388		SGK1	serum/glucocorticoid regulated kinase 1
chr19_+_43447262	0.386		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr17_-_72218661	0.386		MXRA7	matrix-remodelling associated 7
chr8_+_26296439	0.386	NM_004331	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr10_-_3817205	0.386		KLF6	Kruppel-like factor 6
chr2_+_173000552	0.385	NM_000210 NM_001079818	ITGA6	integrin, alpha 6
chr13_+_97593411	0.384	NM_001001715 NM_005766	FARP1	FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr3_-_187025501	0.384	NM_001007225 NM_006548	IGF2BP2	insulin-like growth factor 2 mRNA binding protein 2
chr11_-_27450808	0.383	NM_018490	LGR4	leucine-rich repeat containing G protein-coupled receptor 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.23	8.05e-05	GO:0009966	regulation of signal transduction
1.19	4.80e-03	GO:0023051	regulation of signaling
1.28	5.57e-03	GO:0016192	vesicle-mediated transport
1.30	5.91e-03	GO:0030030	cell projection organization
1.19	5.94e-03	GO:0009653	anatomical structure morphogenesis
1.20	9.17e-03	GO:0033036	macromolecule localization
1.15	1.19e-02	GO:0048523	negative regulation of cellular process
1.16	2.42e-02	GO:0006464	protein modification process
1.18	2.63e-02	GO:0007399	nervous system development
1.29	4.24e-02	GO:0000902	cell morphogenesis
1.28	4.27e-02	GO:0032989	cellular component morphogenesis
1.32	4.41e-02	GO:0007010	cytoskeleton organization
1.20	4.42e-02	GO:0044248	cellular catabolic process
1.34	4.76e-02	GO:0009968	negative regulation of signal transduction

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.10	2.92e-13	GO:0005737	cytoplasm
1.07	1.94e-12	GO:0005622	intracellular
1.06	5.19e-11	GO:0044424	intracellular part
1.11	1.10e-08	GO:0044444	cytoplasmic part
1.07	7.22e-08	GO:0043226	organelle
1.07	1.47e-07	GO:0043229	intracellular organelle
1.03	1.06e-06	GO:0005623	cell
1.03	1.37e-06	GO:0044464	cell part
1.72	1.85e-06	GO:0070161	anchoring junction
1.76	2.62e-06	GO:0005912	adherens junction
1.07	2.64e-05	GO:0043227	membrane-bounded organelle
1.06	6.16e-05	GO:0043231	intracellular membrane-bounded organelle
1.16	1.83e-04	GO:0005829	cytosol
1.20	3.70e-04	GO:0005856	cytoskeleton
1.24	5.37e-04	GO:0005794	Golgi apparatus
1.43	1.29e-03	GO:0015629	actin cytoskeleton
1.31	1.46e-03	GO:0044431	Golgi apparatus part
1.18	2.52e-03	GO:0012505	endomembrane system
1.69	3.78e-03	GO:0005924	cell-substrate adherens junction
1.33	4.21e-03	GO:0000139	Golgi membrane
1.70	4.85e-03	GO:0005925	focal adhesion
1.65	7.48e-03	GO:0030055	cell-substrate junction
1.50	9.97e-03	GO:0031252	cell leading edge
1.28	1.17e-02	GO:0030054	cell junction
1.08	1.17e-02	GO:0044422	organelle part
1.26	1.72e-02	GO:0015630	microtubule cytoskeleton
1.20	4.98e-02	GO:0044430	cytoskeletal part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.39	2.90e-04	GO:0030695	GTPase regulator activity
1.38	4.73e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.32	2.46e-03	GO:0008092	cytoskeletal protein binding
1.06	3.55e-03	GO:0005515	protein binding
1.57	7.89e-03	GO:0005085	guanyl-nucleotide exchange factor activity
1.32	1.22e-02	GO:0019904	protein domain specific binding
1.40	2.02e-02	GO:0005083	small GTPase regulator activity
1.21	4.15e-02	GO:0030234	enzyme regulator activity