Motif ID: PAX5.p2

Z-value: 1.079


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX5chr9_-_37024358-0.068.3e-01Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_43399101 2.947 MAOA
monoamine oxidase A
chr2_-_98713862 2.026 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr8_+_136538739 1.568 NM_006558
 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr3_-_151171190 1.561 NM_002628
NM_053024
 PFN2

profilin 2

chr20_-_23566325 1.471 NM_000099
 CST3
cystatin C
chr2_+_235525355 1.464 NM_014521
 SH3BP4
SH3-domain binding protein 4
chr13_+_26029879 1.401 WASF3
WAS protein family, member 3
chr21_+_17807167 1.339 NM_001338
 CXADR
coxsackie virus and adenovirus receptor
chr2_-_20288647 1.279 NM_001006946
 SDC1
syndecan 1
chr8_+_26427378 1.197 NM_001197293
 DPYSL2
dihydropyrimidinase-like 2
chr3_-_151171576 1.184 PFN2
profilin 2
chr2_-_98714020 1.165 NM_012214
 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr11_+_120828058 1.152 NM_003105
 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr1_-_233879617 1.145 NM_001098722
 GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr12_-_105165805 1.121 NM_006825
 CKAP4
cytoskeleton-associated protein 4
chr14_-_104515738 1.104 NM_138420
 AHNAK2
AHNAK nucleoprotein 2
chr2_-_20288108 1.079 NM_002997
 SDC1
syndecan 1
chr15_+_99237527 1.047 NM_000693
 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr12_-_13044467 1.011 NM_015987
 HEBP1
heme binding protein 1
chr21_-_45118037 0.999 NM_004339
 PTTG1IP
pituitary tumor-transforming 1 interacting protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.34 4.76e-02 GO:0009968 negative regulation of signal transduction
1.32 4.41e-02 GO:0007010 cytoskeleton organization
1.30 5.91e-03 GO:0030030 cell projection organization
1.29 4.24e-02 GO:0000902 cell morphogenesis
1.28 5.57e-03 GO:0016192 vesicle-mediated transport
1.28 4.27e-02 GO:0032989 cellular component morphogenesis
1.23 8.05e-05 GO:0009966 regulation of signal transduction
1.20 9.17e-03 GO:0033036 macromolecule localization
1.20 4.42e-02 GO:0044248 cellular catabolic process
1.19 4.80e-03 GO:0023051 regulation of signaling
1.19 5.94e-03 GO:0009653 anatomical structure morphogenesis
1.18 2.63e-02 GO:0007399 nervous system development
1.16 2.42e-02 GO:0006464 protein modification process
1.15 1.19e-02 GO:0048523 negative regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
1.76 2.62e-06 GO:0005912 adherens junction
1.72 1.85e-06 GO:0070161 anchoring junction
1.70 4.85e-03 GO:0005925 focal adhesion
1.69 3.78e-03 GO:0005924 cell-substrate adherens junction
1.65 7.48e-03 GO:0030055 cell-substrate junction
1.50 9.97e-03 GO:0031252 cell leading edge
1.43 1.29e-03 GO:0015629 actin cytoskeleton
1.33 4.21e-03 GO:0000139 Golgi membrane
1.31 1.46e-03 GO:0044431 Golgi apparatus part
1.28 1.17e-02 GO:0030054 cell junction
1.26 1.72e-02 GO:0015630 microtubule cytoskeleton
1.24 5.37e-04 GO:0005794 Golgi apparatus
1.20 3.70e-04 GO:0005856 cytoskeleton
1.20 4.98e-02 GO:0044430 cytoskeletal part
1.18 2.52e-03 GO:0012505 endomembrane system
1.16 1.83e-04 GO:0005829 cytosol
1.11 1.10e-08 GO:0044444 cytoplasmic part
1.10 2.92e-13 GO:0005737 cytoplasm
1.08 1.17e-02 GO:0044422 organelle part
1.07 1.94e-12 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
1.57 7.89e-03 GO:0005085 guanyl-nucleotide exchange factor activity
1.40 2.02e-02 GO:0005083 small GTPase regulator activity
1.39 2.90e-04 GO:0030695 GTPase regulator activity
1.38 4.73e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.32 2.46e-03 GO:0008092 cytoskeletal protein binding
1.32 1.22e-02 GO:0019904 protein domain specific binding
1.21 4.15e-02 GO:0030234 enzyme regulator activity
1.06 3.55e-03 GO:0005515 protein binding