Motif ID: NFE2.p2

Z-value: 0.975


Transcription factors associated with NFE2.p2:

Gene SymbolEntrez IDGene Name
NFE2 4778 nuclear factor (erythroid-derived 2), 45kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2chr12_-_529757770.116.9e-01Click!


Activity profile for motif NFE2.p2.

activity profile for motif NFE2.p2


Sorted Z-values histogram for motif NFE2.p2

Sorted Z-values for motif NFE2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_35975227 6.134 NM_001838
 CCR7
chemokine (C-C motif) receptor 7
chr22_+_21495273 5.294


chr22_+_21370394 5.090 IGL@
immunoglobulin lambda locus
chr22_+_21053972 4.104


chr22_+_21011653 3.020


chr22_+_21116283 3.012


chr12_-_15005761 2.945 NM_001175
 ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_173111306 2.837 NM_001035230
 RABGAP1L
RAB GTPase activating protein 1-like
chr13_-_98757634 2.825 NM_004951
 GPR183
G protein-coupled receptor 183
chr22_+_21340757 2.687


chr22_+_20899155 2.600


chr22_+_21065134 2.411 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21079355 2.407


chr17_-_26665144 2.373 EVI2B
ecotropic viral integration site 2B
chr17_-_26665213 2.325 EVI2B
ecotropic viral integration site 2B
chrX_-_154216929 2.272 NM_001289
 CLIC2
chloride intracellular channel 2
chr22_+_21065207 2.206 IGLJ3
immunoglobulin lambda joining 3
chr17_-_26665194 2.176 EVI2B
ecotropic viral integration site 2B
chr6_+_33151703 2.116 NM_002121
 HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr22_+_21464980 1.989



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 42 entries
enrichment   p-value GO term description
4.63 4.32e-04 GO:0071158 positive regulation of cell cycle arrest
4.56 1.27e-03 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
4.56 1.27e-03 GO:0072395 signal transduction involved in cell cycle checkpoint
4.56 1.27e-03 GO:0072401 signal transduction involved in DNA integrity checkpoint
4.56 1.27e-03 GO:0072404 signal transduction involved in G1/S transition checkpoint
4.56 1.27e-03 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
4.56 1.27e-03 GO:0072422 signal transduction involved in DNA damage checkpoint
4.56 1.27e-03 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
4.56 1.27e-03 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
4.50 8.67e-03 GO:0006521 regulation of cellular amino acid metabolic process
4.13 4.96e-03 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
4.05 1.41e-02 GO:0033238 regulation of cellular amine metabolic process
3.95 2.13e-03 GO:2000045 regulation of G1/S transition of mitotic cell cycle
3.92 4.87e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
3.92 4.87e-03 GO:0071779 G1/S transition checkpoint
3.80 3.09e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.40 3.41e-02 GO:0030330 DNA damage response, signal transduction by p53 class mediator
3.17 2.75e-02 GO:0000077 DNA damage checkpoint
2.37 4.45e-03 GO:0031401 positive regulation of protein modification process
2.19 3.59e-03 GO:0051247 positive regulation of protein metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
7.26 7.52e-03 GO:0001533 cornified envelope
4.48 2.39e-04 GO:0000502 proteasome complex
1.57 2.26e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.65 2.59e-03 GO:0005126 cytokine receptor binding