Motif ID: PDX1.p2

Z-value: 0.439


Transcription factors associated with PDX1.p2:

Gene SymbolEntrez IDGene Name
PDX1 3651 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PDX1chr13_+_273921360.292.8e-01Click!


Activity profile for motif PDX1.p2.

activity profile for motif PDX1.p2


Sorted Z-values histogram for motif PDX1.p2

Sorted Z-values for motif PDX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PDX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_17624304 1.002 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr11_+_22652894 0.926 NM_005256
GAS2
growth arrest-specific 2
chr8_-_17624009 0.748 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr18_+_54039779 0.587 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr8_+_26569709 0.567 DPYSL2
dihydropyrimidinase-like 2
chr8_-_17599438 0.503 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr4_+_74500748 0.475 ALB
albumin
chr6_-_133076873 0.455 NM_004666
VNN1
vanin 1
chr16_+_69115225 0.438 SF3B3
splicing factor 3b, subunit 3, 130kDa
chrX_-_131375217 0.408 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr16_+_69115227 0.382 SF3B3
splicing factor 3b, subunit 3, 130kDa
chr17_-_7023378 0.358 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr18_+_54039730 0.357 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr16_+_18986459 0.328 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr22_-_16070778 0.242 NM_017424
CECR1
cat eye syndrome chromosome region, candidate 1
chr4_-_155753249 0.241 FGG
fibrinogen gamma chain
chr16_+_18986417 0.236 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_-_121883647 0.234 HGD
homogentisate 1,2-dioxygenase
chr3_+_46594079 0.231 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr18_+_54039818 0.226 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr4_+_89115825 0.210 NM_000582
NM_001040058
NM_001040060
SPP1


secreted phosphoprotein 1


chr2_-_188127294 0.194 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr12_-_101835510 0.185 NM_000277
PAH
phenylalanine hydroxylase
chr16_+_18986721 0.185 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_167624792 0.183 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr2_-_188127430 0.170 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr8_-_81155564 0.164 NM_001025252
TPD52
tumor protein D52
chr19_-_7672978 0.154 NM_002002
FCER2
Fc fragment of IgE, low affinity II, receptor for (CD23)
chr21_-_45173061 0.154 NM_001127491
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr6_-_134540666 0.150 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr4_+_187424336 0.112 F11
coagulation factor XI
chr3_+_101720753 0.111 TMEM45A
transmembrane protein 45A
chr2_-_158008763 0.094 NM_004288
CYTIP
cytohesin 1 interacting protein
chr12_-_52306348 0.084 NM_001130060
NM_006856
ATF7

activating transcription factor 7

chr2_-_199922047 0.079 SATB2
SATB homeobox 2
chr1_-_161379606 0.077 RGS5
regulator of G-protein signaling 5
chr17_+_7900926 0.072


chr1_+_28637247 0.070 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr6_+_144654565 0.066 NM_007124
UTRN
utrophin
chr6_-_46933901 0.066 GPR116
G protein-coupled receptor 116
chr16_+_69115189 0.062 NM_012426
SF3B3
splicing factor 3b, subunit 3, 130kDa
chr1_+_157441133 0.061 NM_002036
DARC
Duffy blood group, chemokine receptor
chr17_+_7423685 0.060 CD68
CD68 molecule
chr2_+_38746742 0.058 GALM
galactose mutarotase (aldose 1-epimerase)
chr4_+_74825138 0.057 NM_000584
IL8
interleukin 8
chr6_+_158653679 0.057 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr4_+_187424111 0.056 NM_000128
F11
coagulation factor XI
chr12_+_108061584 0.055 NM_001093
ACACB
acetyl-CoA carboxylase beta
chr3_+_52786642 0.052 NM_002215
ITIH1
inter-alpha (globulin) inhibitor H1
chr16_-_21078262 0.051 NM_017539
DNAH3
dynein, axonemal, heavy chain 3
chrX_+_48978875 0.049 CCDC22
coiled-coil domain containing 22
chr2_-_218516950 0.044 NM_022648
TNS1
tensin 1
chr2_+_105799354 0.040 NCK2
NCK adaptor protein 2
chr1_+_57093030 0.040 NM_000562
C8A
complement component 8, alpha polypeptide
chr12_+_4569504 0.038 NM_003845
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr17_+_7423528 0.036 NM_001251
NM_001040059
CD68

CD68 molecule

chr17_-_39499527 0.035 LSM12
LSM12 homolog (S. cerevisiae)
chr17_+_7423662 0.033 CD68
CD68 molecule
chr6_-_31215089 0.032 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr3_-_47909001 0.031 MAP4
microtubule-associated protein 4
chr3_+_149930656 0.031 NM_032049
AGTR1
angiotensin II receptor, type 1
chrX_+_48978870 0.030 NM_014008
CCDC22
coiled-coil domain containing 22
chr11_-_66201894 0.029 RBM4B
RNA binding motif protein 4B
chr4_-_47831002 0.027 NM_003328
TXK
TXK tyrosine kinase
chr17_-_26665213 0.027 EVI2B
ecotropic viral integration site 2B
chr16_-_66075216 0.026 NM_001138
AGRP
agouti related protein homolog (mouse)
chr2_-_165768798 0.026 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chrX_+_99786044 0.026 SRPX2
sushi-repeat containing protein, X-linked 2
chr17_-_26665220 0.026 NM_006495
EVI2B
ecotropic viral integration site 2B
chr3_+_11153778 0.022 NM_001098213
HRH1
histamine receptor H1
chr1_+_78858675 0.021 NM_006820
IFI44L
interferon-induced protein 44-like
chr14_+_38653177 0.018 NM_001009182
NM_001009183
NM_003616
SIP1


survival of motor neuron protein interacting protein 1


chr3_-_115826481 0.018 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_28088406 0.016 METTL15
methyltransferase like 15
chr6_-_123999640 0.016 NM_006073
TRDN
triadin
chr12_-_89922888 0.016 NM_004950
EPYC
epiphycan
chr11_-_5130174 0.016 NM_012375
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr19_-_56229808 0.015 NM_019598
NM_145894
NM_145895
KLK12


kallikrein-related peptidase 12


chr1_+_12900031 0.014 NM_001012277
PRAMEF7
PRAME family member 7
chr17_-_39500512 0.014 NM_152344
LSM12
LSM12 homolog (S. cerevisiae)
chrX_+_99785818 0.012 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr6_-_41362370 0.011 NM_018643
TREM1
triggering receptor expressed on myeloid cells 1
chr17_-_39499463 0.011 LSM12
LSM12 homolog (S. cerevisiae)
chr12_-_89922875 0.011 EPYC
epiphycan
chr9_+_137553104 0.011 NM_002297
LCN1
lipocalin 1 (tear prealbumin)
chr1_-_31251315 0.010 PUM1
pumilio homolog 1 (Drosophila)
chr8_-_20084892 0.007 NM_001135691
NM_001142324
NM_001142325
NM_003053
SLC18A1



solute carrier family 18 (vesicular monoamine), member 1



chr1_-_159786441 0.007 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr16_-_70339666 0.006 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr7_+_150376537 0.006 NM_004769
NM_020321
NM_020322
ACCN3


amiloride-sensitive cation channel 3


chr1_-_202402043 0.006 NM_000537
REN
renin
chr1_-_33613729 0.005 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr10_+_70650064 0.005 NM_025130
HKDC1
hexokinase domain containing 1
chrX_-_62697473 0.005 LOC92249
hypothetical LOC92249
chr10_+_80942362 0.005 NM_001099692
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr6_+_160247962 0.004 NM_002377
MAS1
MAS1 oncogene
chr17_+_7423704 0.001 CD68
CD68 molecule
chr12_-_10853940 0.001 NM_023917
TAS2R9
taste receptor, type 2, member 9
chr2_-_46988449 0.001 MCFD2
multiple coagulation factor deficiency 2
chrX_+_37524250 0.001 CYBB
cytochrome b-245, beta polypeptide
chr17_-_36444626 0.001 NM_030966
KRTAP1-3
keratin associated protein 1-3
chr4_-_176970895 0.000 GPM6A
glycoprotein M6A

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.40 9.12e-03 GO:0005576 extracellular region

Nothing significant found in function category.