Motif ID: EP300.p2

Z-value: 2.214


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EP300chr22_+_39817733-0.702.7e-03Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_113546841 6.692 NM_000820
 GAS6
growth arrest-specific 6
chr12_+_6179736 6.303 NM_001769
 CD9
CD9 molecule
chr10_-_126839546 6.228 NM_001083914
 CTBP2
C-terminal binding protein 2
chr13_+_113546897 5.394 GAS6
growth arrest-specific 6
chrX_-_140098941 5.388 LDOC1
leucine zipper, down-regulated in cancer 1
chrX_-_140098959 4.658 NM_012317
 LDOC1
leucine zipper, down-regulated in cancer 1
chrX_-_140099014 4.636 LDOC1
leucine zipper, down-regulated in cancer 1
chr13_+_113546912 4.296 GAS6
growth arrest-specific 6
chr14_-_104515738 4.123 NM_138420
 AHNAK2
AHNAK nucleoprotein 2
chr13_+_113546943 3.927 GAS6
growth arrest-specific 6
chr11_+_35116961 3.362 NM_000610
NM_001001389
NM_001001390
NM_001001391
NM_001001392
 CD44




CD44 molecule (Indian blood group)




chr1_-_94779727 3.338 NM_001178096
NM_001993
 F3

coagulation factor III (thromboplastin, tissue factor)

chr4_-_177950658 3.157 NM_005429
 VEGFC
vascular endothelial growth factor C
chr2_+_71149193 3.019 NAGK
N-acetylglucosamine kinase
chr13_-_39075304 2.908 LHFP
lipoma HMGIC fusion partner
chr18_-_20231783 2.860 NM_080597
 OSBPL1A
oxysterol binding protein-like 1A
chr11_+_35117226 2.838 CD44
CD44 molecule (Indian blood group)
chr1_+_26479167 2.783 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr7_+_115952279 2.780 NM_001172895
 CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_115952074 2.773 NM_001753
 CAV1
caveolin 1, caveolae protein, 22kDa

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.65 4.22e-02 GO:0030029 actin filament-based process
1.50 2.85e-04 GO:0016192 vesicle-mediated transport

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.24 3.23e-04 GO:0030055 cell-substrate junction
2.24 9.01e-04 GO:0005925 focal adhesion
2.21 9.44e-04 GO:0005924 cell-substrate adherens junction
2.14 8.22e-06 GO:0070161 anchoring junction
2.11 8.19e-05 GO:0005912 adherens junction
1.87 7.85e-05 GO:0016323 basolateral plasma membrane
1.87 2.33e-03 GO:0031252 cell leading edge
1.74 2.00e-04 GO:0015629 actin cytoskeleton
1.50 1.26e-03 GO:0030054 cell junction
1.27 1.51e-02 GO:0005856 cytoskeleton
1.09 4.78e-04 GO:0005737 cytoplasm
1.09 3.55e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.72 3.15e-04 GO:0003779 actin binding
1.56 1.97e-04 GO:0008092 cytoskeletal protein binding
1.10 2.81e-03 GO:0005515 protein binding