Motif ID: EP300.p2

Z-value: 2.214


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
EP300 2033 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EP300chr22_+_39817733-0.702.7e-03Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_113546841 6.692 NM_000820
GAS6
growth arrest-specific 6
chr12_+_6179736 6.303 NM_001769
CD9
CD9 molecule
chr10_-_126839546 6.228 NM_001083914
CTBP2
C-terminal binding protein 2
chr13_+_113546897 5.394 GAS6
growth arrest-specific 6
chrX_-_140098941 5.388 LDOC1
leucine zipper, down-regulated in cancer 1
chrX_-_140098959 4.658 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chrX_-_140099014 4.636 LDOC1
leucine zipper, down-regulated in cancer 1
chr13_+_113546912 4.296 GAS6
growth arrest-specific 6
chr14_-_104515738 4.123 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr13_+_113546943 3.927 GAS6
growth arrest-specific 6
chr11_+_35116961 3.362 NM_000610
NM_001001389
NM_001001390
NM_001001391
NM_001001392
CD44




CD44 molecule (Indian blood group)




chr1_-_94779727 3.338 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr4_-_177950658 3.157 NM_005429
VEGFC
vascular endothelial growth factor C
chr2_+_71149193 3.019 NAGK
N-acetylglucosamine kinase
chr13_-_39075304 2.908 LHFP
lipoma HMGIC fusion partner
chr18_-_20231783 2.860 NM_080597
OSBPL1A
oxysterol binding protein-like 1A
chr11_+_35117226 2.838 CD44
CD44 molecule (Indian blood group)
chr1_+_26479167 2.783 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr7_+_115952279 2.780 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr7_+_115952074 2.773 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr18_-_20231709 2.600 OSBPL1A
oxysterol binding protein-like 1A
chr14_-_68515791 2.561 NM_001102
NM_001130004
NM_001130005
ACTN1


actinin, alpha 1


chr7_+_115952325 2.447 CAV1
caveolin 1, caveolae protein, 22kDa
chrX_+_135057202 2.432 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr14_-_68515761 2.320 ACTN1
actinin, alpha 1
chr14_-_68515731 2.293 ACTN1
actinin, alpha 1
chr3_+_156280129 2.255 NM_000902
MME
membrane metallo-endopeptidase
chr14_-_68515727 2.244 ACTN1
actinin, alpha 1
chr14_-_68515742 2.230 ACTN1
actinin, alpha 1
chr3_-_31998241 2.224 NM_001174060
NM_017784
OSBPL10

oxysterol binding protein-like 10

chr5_+_96024434 2.196 CAST
calpastatin
chr14_-_68515701 2.179 ACTN1
actinin, alpha 1
chr14_-_50480857 2.104 NM_001163940
NM_002863
PYGL

phosphorylase, glycogen, liver

chr9_-_116920232 2.076 NM_002160
TNC
tenascin C
chr1_-_108544486 2.059 NM_013386
SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chr3_+_156280604 2.055 NM_007288
MME
membrane metallo-endopeptidase
chr8_-_145085616 2.030 NM_201384
PLEC
plectin
chr3_+_156280338 2.030 NM_007287
MME
membrane metallo-endopeptidase
chr1_-_20685314 2.012 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr10_+_121401061 2.000 BAG3
BCL2-associated athanogene 3
chr2_-_189752575 1.935 NM_000393
COL5A2
collagen, type V, alpha 2
chr1_+_26479208 1.918 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr2_-_109728958 1.831 NM_144710
NM_178584
SEPT10

septin 10

chr8_+_15442106 1.808 TUSC3
tumor suppressor candidate 3
chr8_+_15442100 1.782 NM_006765
NM_178234
TUSC3

tumor suppressor candidate 3

chr11_+_113672407 1.763 NNMT
nicotinamide N-methyltransferase
chrX_+_135079120 1.761 NM_001159704
FHL1
four and a half LIM domains 1
chr17_+_58058783 1.760 MRC2
mannose receptor, C type 2
chr1_-_154913712 1.720 NM_006617
NES
nestin
chr12_-_104153920 1.692 NM_018171
APPL2
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr5_-_39461054 1.681 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_-_21483457 1.678 NDN
necdin homolog (mouse)
chr10_+_102782156 1.673 SFXN3
sideroflexin 3
chr4_+_75529716 1.660 NM_001657
AREG
amphiregulin
chr2_+_191818124 1.639 NM_001130158
NM_012223
NM_001161819
MYO1B


myosin IB


chr4_+_75699652 1.637 NM_001657
AREG
amphiregulin
chr8_+_15442123 1.627 TUSC3
tumor suppressor candidate 3
chr18_-_20105814 1.626 OSBPL1A
oxysterol binding protein-like 1A
chr1_-_151804929 1.622 NM_005978
S100A2
S100 calcium binding protein A2
chr1_+_26479173 1.579 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr3_-_51971915 1.565 NM_033010
PCBP4
poly(rC) binding protein 4
chr15_-_21483503 1.538 NM_002487
NDN
necdin homolog (mouse)
chr18_-_20105644 1.517 OSBPL1A
oxysterol binding protein-like 1A
chr13_-_39075355 1.514 NM_005780
LHFP
lipoma HMGIC fusion partner
chr8_+_31616809 1.501 NM_013962
NRG1
neuregulin 1
chr12_-_26169074 1.489 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chrX_+_37093448 1.482 NM_000950
NM_001142395
NM_001173486
NM_001173489
NM_001173490
PRRG1




proline rich Gla (G-carboxyglutamic acid) 1




chr5_-_39460687 1.479 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr8_-_23317571 1.470 LOXL2
lysyl oxidase-like 2
chr1_+_221955876 1.459 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr6_-_86409369 1.456 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_+_26479030 1.433 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_108544261 1.430 SLC25A24
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24
chrX_+_133993984 1.428 NM_001078171
FAM127A
family with sequence similarity 127, member A
chr13_-_39075200 1.420 LHFP
lipoma HMGIC fusion partner
chr18_-_20106187 1.418 NM_018030
OSBPL1A
oxysterol binding protein-like 1A
chr8_-_23317536 1.415 LOXL2
lysyl oxidase-like 2
chr10_+_88718167 1.409 NM_006829
C10orf116
chromosome 10 open reading frame 116
chr10_+_17311347 1.407 VIM
vimentin
chr1_+_156229686 1.405 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr1_-_58815415 1.400 TACSTD2
tumor-associated calcium signal transducer 2
chr15_+_72005847 1.400 LOXL1
lysyl oxidase-like 1
chr20_-_55719946 1.388 NM_199171
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_-_122722674 1.384 NM_005328
HAS2
hyaluronan synthase 2
chr14_-_68515525 1.383 ACTN1
actinin, alpha 1
chr15_+_72005839 1.375 NM_005576
LOXL1
lysyl oxidase-like 1
chr3_+_157875408 1.372 NM_001184717
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr1_+_154351200 1.371 LMNA
lamin A/C
chr11_+_35117242 1.357 CD44
CD44 molecule (Indian blood group)
chr1_-_93919789 1.346 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr10_+_53744043 1.331 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr9_+_19039355 1.330 NM_006570
RRAGA
Ras-related GTP binding A
chr11_+_113672378 1.329 NNMT
nicotinamide N-methyltransferase
chr9_+_19039417 1.329 RRAGA
Ras-related GTP binding A
chr1_-_68470585 1.315 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr9_+_19039376 1.314 RRAGA
Ras-related GTP binding A
chr15_+_68971835 1.300 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr6_-_110607857 1.293 NM_001024934
NM_001024935
NM_001024936
NM_003931
WASF1



WAS protein family, member 1



chr9_+_19039408 1.292 RRAGA
Ras-related GTP binding A
chr14_-_66948612 1.290 PLEK2
pleckstrin 2
chr8_+_95801277 1.285 NM_181787
DPY19L4
dpy-19-like 4 (C. elegans)
chrX_-_3274680 1.283 NM_015419
MXRA5
matrix-remodelling associated 5
chr5_-_39460787 1.282 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr11_+_35117391 1.282 CD44
CD44 molecule (Indian blood group)
chr6_-_138470160 1.270 NM_022121
PERP
PERP, TP53 apoptosis effector
chr16_+_69060325 1.262 FUK
fucokinase
chr14_+_22410795 1.260 NM_014045
LRP10
low density lipoprotein receptor-related protein 10
chr12_-_8706533 1.259 MFAP5
microfibrillar associated protein 5
chr19_-_18913011 1.257 HOMER3
homer homolog 3 (Drosophila)
chr5_+_34720368 1.254 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr19_-_18913017 1.253 HOMER3
homer homolog 3 (Drosophila)
chr15_+_72005875 1.247 LOXL1
lysyl oxidase-like 1
chr3_+_157875063 1.242 TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr19_-_18913032 1.240 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr20_+_9236446 1.235 NM_000933
PLCB4
phospholipase C, beta 4
chr15_+_72005864 1.225 LOXL1
lysyl oxidase-like 1
chr2_+_71148915 1.224 NM_017567
NAGK
N-acetylglucosamine kinase
chr7_+_48095464 1.217 UPP1
uridine phosphorylase 1
chr14_-_66948523 1.207 NM_016445
PLEK2
pleckstrin 2
chr1_-_153213425 1.206 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr2_-_109728693 1.205 SEPT10
septin 10
chr5_+_131621287 1.202 PDLIM4
PDZ and LIM domain 4
chr3_+_157874898 1.184 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr9_+_19039424 1.166 RRAGA
Ras-related GTP binding A
chr1_-_153213454 1.147 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr1_-_95165037 1.141 CNN3
calponin 3, acidic
chr8_-_119192985 1.140 NM_000127
EXT1
exostosin 1
chr8_+_61592278 1.115 RAB2A
RAB2A, member RAS oncogene family
chr11_+_66580884 1.112 RHOD
ras homolog gene family, member D
chrX_-_17789276 1.104 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr4_+_169789327 1.094 NM_001166109
PALLD
palladin, cytoskeletal associated protein
chr20_-_14266200 1.094 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr1_-_153213483 1.093 NM_001130041
NM_003029
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr2_-_168812132 1.091 NM_013233
STK39
serine threonine kinase 39
chr11_-_46678691 1.091 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr11_+_35117408 1.088 CD44
CD44 molecule (Indian blood group)
chr8_+_22492198 1.086 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr7_-_45927263 1.081 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr20_+_42537927 1.081 NM_001039199
NM_024331
TTPAL

tocopherol (alpha) transfer protein-like

chr13_-_105985313 1.079 NM_004093
EFNB2
ephrin-B2
chr1_+_26478799 1.067 NM_031286
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr6_-_47385605 1.067 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr17_-_4792542 1.067 NM_005022
PFN1
profilin 1
chr8_-_145090045 1.065 NM_201382
PLEC
plectin
chrX_-_133984157 1.060 NM_001078173
FAM127C
family with sequence similarity 127, member C
chr12_-_51173238 1.055 NM_005554
KRT6A
keratin 6A
chr15_+_72006015 1.055 LOXL1
lysyl oxidase-like 1
chr12_-_53099269 1.046 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr9_-_33437527 1.039 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr1_-_85703321 1.037 NM_012137
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr17_+_58058774 1.034 MRC2
mannose receptor, C type 2
chr4_+_6627816 1.033 MAN2B2
mannosidase, alpha, class 2B, member 2
chr5_+_131621230 1.026 NM_001131027
NM_003687
PDLIM4

PDZ and LIM domain 4

chr6_-_110607496 1.025 WASF1
WAS protein family, member 1
chr14_-_69896146 1.013 NM_016468
COX16
COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr3_-_31997738 1.004 OSBPL10
oxysterol binding protein-like 10
chr4_-_40553838 1.001 NM_001166051
NM_001166052
NM_001166053
NM_001166054
APBB2



amyloid beta (A4) precursor protein-binding, family B, member 2



chr12_-_122684150 1.000 NM_001414
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr3_+_132095496 0.999 ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr19_+_16157198 0.997 NM_014077
FAM32A
family with sequence similarity 32, member A
chr1_-_32940943 0.995 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr7_+_128257698 0.989 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr5_+_82803248 0.983 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr19_-_60350118 0.975 TNNT1
troponin T type 1 (skeletal, slow)
chr2_-_229844198 0.972 NM_001100818
NM_017933
PID1

phosphotyrosine interaction domain containing 1

chr12_-_53099203 0.963 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr16_-_30993004 0.961 NM_024706
ZNF668
zinc finger protein 668
chr2_+_46377952 0.956 NM_001430
EPAS1
endothelial PAS domain protein 1
chr12_-_53099277 0.952 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_+_20788027 0.952 NM_001785
CDA
cytidine deaminase
chr5_+_131621276 0.951 PDLIM4
PDZ and LIM domain 4
chr9_-_34610489 0.950 NM_007234
NM_024348
DCTN3

dynactin 3 (p22)

chr17_-_4792572 0.946 PFN1
profilin 1
chr11_-_119514011 0.940 TRIM29
tripartite motif containing 29
chr6_+_125516499 0.939 NM_001003396
NM_001003397
NM_003287
TPD52L1


tumor protein D52-like 1


chr10_-_3817418 0.938 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr6_-_47385470 0.929 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr8_+_32623792 0.922 NM_013959
NRG1
neuregulin 1
chr9_-_34610483 0.918 DCTN3
dynactin 3 (p22)
chr1_-_120413798 0.917 NM_024408
NOTCH2
notch 2
chr7_+_68702252 0.916 AUTS2
autism susceptibility candidate 2
chr12_+_47498778 0.916 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr4_-_81213207 0.911


chr5_+_119827797 0.910 PRR16
proline rich 16
chr9_+_33740463 0.907 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chr2_+_187162969 0.902 NM_001145000
NM_002210
ITGAV

integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)

chr12_+_52696908 0.896 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chrX_-_51256166 0.896 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr7_-_150605112 0.872 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr9_-_34610460 0.871 DCTN3
dynactin 3 (p22)
chr12_+_21481804 0.867 NM_024854
PYROXD1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr16_+_55836480 0.861 NM_012106
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr12_-_105165805 0.857 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr4_-_57671273 0.857 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr15_-_71712711 0.852 NM_001161363
NM_001161364
NM_012428
NM_017455
NPTN



neuroplastin



chr11_-_27677755 0.844 NM_170734
BDNF
brain-derived neurotrophic factor
chr10_-_49483002 0.842 NM_021226
ARHGAP22
Rho GTPase activating protein 22
chr4_-_84475023 0.835 HPSE
heparanase
chr6_+_7486862 0.834 NM_001008844
NM_004415
DSP

desmoplakin

chr12_+_69046241 0.834 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.50 2.85e-04 GO:0016192 vesicle-mediated transport
1.65 4.22e-02 GO:0030029 actin filament-based process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.14 8.22e-06 GO:0070161 anchoring junction
1.87 7.85e-05 GO:0016323 basolateral plasma membrane
2.11 8.19e-05 GO:0005912 adherens junction
1.74 2.00e-04 GO:0015629 actin cytoskeleton
2.24 3.23e-04 GO:0030055 cell-substrate junction
1.09 4.78e-04 GO:0005737 cytoplasm
2.24 9.01e-04 GO:0005925 focal adhesion
2.21 9.44e-04 GO:0005924 cell-substrate adherens junction
1.50 1.26e-03 GO:0030054 cell junction
1.87 2.33e-03 GO:0031252 cell leading edge
1.27 1.51e-02 GO:0005856 cytoskeleton
1.09 3.55e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.56 1.97e-04 GO:0008092 cytoskeletal protein binding
1.72 3.15e-04 GO:0003779 actin binding
1.10 2.81e-03 GO:0005515 protein binding