Motif ID: TCF4_dimer.p2

Z-value: 2.422


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF4chr18_-_514068410.476.4e-02Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr15_+_72006015 8.915 LOXL1
lysyl oxidase-like 1
chr9_-_35679799 6.343 TPM2
tropomyosin 2 (beta)
chr9_-_35679902 6.126 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr15_+_72005847 5.759 LOXL1
lysyl oxidase-like 1
chr15_+_72005839 5.661 NM_005576
LOXL1
lysyl oxidase-like 1
chr15_-_46725087 5.501 NM_000138
FBN1
fibrillin 1
chr4_-_81213207 5.401


chr2_+_219991342 4.868 NM_001927
DES
desmin
chr9_-_74757735 4.591 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr8_-_49996353 3.964 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr7_+_115953582 3.937 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr7_-_45927263 3.868 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr2_+_170074457 3.831 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr6_-_139737042 3.757 NM_001168389
NM_001168388
CITED2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

chr3_-_87122936 3.536 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr21_+_46355797 3.490 COL6A2
collagen, type VI, alpha 2
chr7_-_130891861 3.406 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr11_+_65536037 3.278 NM_001323
CST6
cystatin E/M
chr2_-_175337386 3.079 NM_000079
NM_001039523
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr15_+_72005875 3.005 LOXL1
lysyl oxidase-like 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.74 5.99e-04 GO:0007517 muscle organ development
1.70 5.58e-03 GO:0006936 muscle contraction
1.63 2.02e-02 GO:0003012 muscle system process
1.61 8.87e-04 GO:0061061 muscle structure development
1.37 2.66e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.37 1.41e-02 GO:0048666 neuron development
1.36 6.22e-05 GO:0048468 cell development
1.36 3.33e-03 GO:0030182 neuron differentiation
1.35 2.51e-03 GO:0016192 vesicle-mediated transport
1.34 5.74e-04 GO:0022008 neurogenesis
1.34 8.08e-04 GO:0048699 generation of neurons
1.26 4.19e-04 GO:0007399 nervous system development
1.22 4.88e-04 GO:0030154 cell differentiation
1.22 6.39e-04 GO:0048869 cellular developmental process
1.19 3.55e-06 GO:0048856 anatomical structure development
1.18 3.27e-04 GO:0048731 system development
1.17 8.96e-05 GO:0007275 multicellular organismal development
1.16 6.63e-05 GO:0032502 developmental process
1.14 6.17e-05 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
2.12 7.71e-07 GO:0044449 contractile fiber part
2.12 1.26e-05 GO:0030017 sarcomere
2.10 9.25e-07 GO:0030016 myofibril
2.07 6.12e-07 GO:0043292 contractile fiber
1.90 3.62e-02 GO:0042383 sarcolemma
1.53 8.18e-04 GO:0015629 actin cytoskeleton
1.51 4.07e-04 GO:0031012 extracellular matrix
1.49 8.05e-03 GO:0005578 proteinaceous extracellular matrix
1.30 4.56e-03 GO:0031982 vesicle
1.29 1.05e-02 GO:0031410 cytoplasmic vesicle
1.29 1.64e-02 GO:0031988 membrane-bounded vesicle
1.29 2.69e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.20 1.82e-02 GO:0005856 cytoskeleton
1.17 6.06e-03 GO:0005829 cytosol
1.10 4.55e-04 GO:0044444 cytoplasmic part
1.09 7.58e-07 GO:0005737 cytoplasm
1.09 7.78e-04 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
2.23 2.94e-02 GO:0008307 structural constituent of muscle
1.77 2.20e-02 GO:0019838 growth factor binding
1.46 1.78e-02 GO:0003779 actin binding
1.38 5.39e-03 GO:0008092 cytoskeletal protein binding