Motif ID: NFE2L2.p2

Z-value: 1.807


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L2chr2_-_177837540-0.837.6e-05Click!


Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_21340757 10.265


chr22_+_21116283 6.207


chrX_-_154216929 5.891 NM_001289
CLIC2
chloride intracellular channel 2
chr22_+_21370394 5.862 IGL@
immunoglobulin lambda locus
chr22_+_21065134 5.806 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21053972 5.446


chr22_+_21065207 5.330 IGLJ3
immunoglobulin lambda joining 3
chr22_+_20899155 5.201


chr22_+_21079355 4.852


chrX_-_100527799 4.687 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr22_+_21495273 4.613


chr22_+_21011653 4.484


chr14_-_106038573 3.794 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_106270497 3.714 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr22_+_21559959 3.689 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr22_+_21407066 3.684


chr9_-_122728173 3.653 TRAF1
TNF receptor-associated factor 1
chr14_-_106084519 3.321 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_+_27795633 3.128 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_-_25642962 3.043 NM_000386
BLMH
bleomycin hydrolase
chr6_-_24985432 2.823 NM_015864
FAM65B
family with sequence similarity 65, member B
chr14_-_105804211 2.735 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_105997732 2.691 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_-_35975227 2.636 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr13_-_98757634 2.602 NM_004951
GPR183
G protein-coupled receptor 183
chrX_+_12903145 2.593 NM_021109
NM_183049
TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr22_+_21065202 2.415


chr17_+_27795635 2.345 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr22_+_21552897 2.209 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21042091 2.170 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr6_+_84626146 2.092 CYB5R4
cytochrome b5 reductase 4
chr3_-_99724047 2.091 CLDND1
claudin domain containing 1
chr11_+_67107852 2.082 GSTP1
glutathione S-transferase pi 1
chr1_-_199259447 2.047 NM_017596
KIF21B
kinesin family member 21B
chr8_-_42742729 2.035 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr3_-_58175437 2.010 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr14_-_105712630 1.962 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_84626113 1.961 CYB5R4
cytochrome b5 reductase 4
chr15_+_86983038 1.952 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr17_+_27795598 1.940 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr8_-_30704762 1.929 GSR
glutathione reductase
chr14_+_102672745 1.927 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr17_-_26665213 1.912 EVI2B
ecotropic viral integration site 2B
chr11_+_67107641 1.901 NM_000852
GSTP1
glutathione S-transferase pi 1
chr1_-_223683141 1.853 NM_194442
LBR
lamin B receptor
chr16_+_27346079 1.847 NM_021798
IL21R
interleukin 21 receptor
chr11_+_10433241 1.828 NM_001025389
AMPD3
adenosine monophosphate deaminase 3
chr12_-_15005761 1.822 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr17_+_27795632 1.812 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr22_+_21006814 1.808


chr10_-_6059460 1.788 NM_002189
NM_172200
IL15RA

interleukin 15 receptor, alpha

chr22_+_21484240 1.788


chr17_+_27795607 1.773 NM_002815
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr14_-_105610144 1.739 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_+_84626083 1.729 NM_016230
CYB5R4
cytochrome b5 reductase 4
chr11_+_118463906 1.600 NM_001024382
HMBS
hydroxymethylbilane synthase
chr1_+_153232685 1.586 NM_018655
LENEP
lens epithelial protein
chr10_-_76538859 1.558 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr1_-_156923111 1.549 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr7_+_150319076 1.524 NM_000603
NOS3
nitric oxide synthase 3 (endothelial cell)
chr22_+_21027538 1.498


chr6_+_36518521 1.498 NM_173562
KCTD20
potassium channel tetramerisation domain containing 20
chr6_+_36518778 1.487 KCTD20
potassium channel tetramerisation domain containing 20
chr7_+_150065376 1.453 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr12_-_101115677 1.437 NM_002674
PMCH
pro-melanin-concentrating hormone
chr22_+_21094094 1.434


chr17_+_27795645 1.429 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr16_+_29984591 1.428 ALDOA
aldolase A, fructose-bisphosphate
chr15_-_32875040 1.415 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr6_+_44302973 1.398 SLC29A1
solute carrier family 29 (nucleoside transporters), member 1
chr3_+_48482213 1.361 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr9_+_129962292 1.316 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr17_+_71109734 1.305 MYO15B
myosin XVB pseudogene
chr12_-_8656705 1.291 NM_020661
AICDA
activation-induced cytidine deaminase
chr19_-_6621598 1.265 NM_003807
NM_172014
TNFSF14

tumor necrosis factor (ligand) superfamily, member 14

chr3_-_99724438 1.263 CLDND1
claudin domain containing 1
chr1_+_12046020 1.257 NM_001243
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr16_+_29984544 1.234 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr2_+_74635019 1.232 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr7_+_130445394 1.231 NM_001145354
MKLN1
muskelin 1, intracellular mediator containing kelch motifs
chr19_-_6621078 1.220 TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chrX_-_109570113 1.216 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr22_-_30388165 1.211 PISD
phosphatidylserine decarboxylase
chr1_-_146543016 1.206


chr7_+_150065594 1.191 GIMAP5
GTPase, IMAP family member 5
chr6_-_35804337 1.178 NM_001145775
FKBP5
FK506 binding protein 5
chr1_-_244647333 1.172 NM_022743
SMYD3
SET and MYND domain containing 3
chr15_+_79276273 1.167 NM_001172128
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr6_-_154719560 1.140 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr16_+_29984611 1.139 ALDOA
aldolase A, fructose-bisphosphate
chr14_+_102870431 1.127 EIF5
eukaryotic translation initiation factor 5
chr19_-_61039939 1.109 NM_145007
NLRP11
NLR family, pyrin domain containing 11
chr16_+_29984621 1.086 ALDOA
aldolase A, fructose-bisphosphate
chr5_+_179057968 1.073 CANX
calnexin
chr3_-_99724373 1.052 CLDND1
claudin domain containing 1
chr22_+_20880159 1.045 IGLV6-57
immunoglobulin lambda variable 6-57
chr6_-_35996794 1.043 SRPK1
SRSF protein kinase 1
chr22_+_21393107 1.029 IGLJ3
immunoglobulin lambda joining 3
chr10_+_85889164 1.026 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr3_+_48482625 1.022 TREX1
three prime repair exonuclease 1
chr17_-_26665220 1.006 NM_006495
EVI2B
ecotropic viral integration site 2B
chr16_+_29984647 0.990 ALDOA
aldolase A, fructose-bisphosphate
chr3_+_185377341 0.982 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr6_+_106653429 0.978 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr13_-_40491405 0.975 ELF1
E74-like factor 1 (ets domain transcription factor)
chr7_+_139175420 0.943 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr22_+_20880112 0.919


chrX_+_119622570 0.910 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr4_-_40212670 0.904 NM_019027
RBM47
RNA binding motif protein 47
chr11_-_3818759 0.894 NM_001665
RHOG
ras homolog gene family, member G (rho G)
chr14_-_105589467 0.887 LOC100126583
IGHA1
IGHG1
IGHG2
IGHM
hypothetical LOC100126583
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr12_-_74764614 0.882 NAP1L1
nucleosome assembly protein 1-like 1
chr21_+_31953803 0.867 NM_000454
SOD1
superoxide dismutase 1, soluble
chr15_+_79304694 0.853 NM_172217
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr14_-_22354851 0.850 NM_001126105
NM_003982
SLC7A7

solute carrier family 7 (cationic amino acid transporter, y+ system), member 7

chr6_+_44322764 0.839 NM_007355
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr6_+_32229278 0.835 NM_138717
PPT2
palmitoyl-protein thioesterase 2
chrX_-_119329307 0.832 FAM70A
family with sequence similarity 70, member A
chr8_-_59734957 0.831 NM_003580
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr6_+_44322831 0.830 HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr8_-_59734939 0.830 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr17_-_26665194 0.827 EVI2B
ecotropic viral integration site 2B
chr1_-_148475065 0.826 ANP32E
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_146543102 0.825


chrX_-_119329334 0.823 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr19_-_6542012 0.813 CD70
CD70 molecule
chr7_+_111850367 0.811 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr18_-_51219880 0.800 TCF4
transcription factor 4
chr1_-_109770567 0.799 PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr16_-_1369613 0.790 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr11_+_10434056 0.787 NM_001025390
AMPD3
adenosine monophosphate deaminase 3
chr22_+_21359175 0.784 IGLV3-25
immunoglobulin lambda variable 3-25
chr6_+_150112537 0.763 PCMT1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_+_106991638 0.762 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr5_+_159368721 0.759 TTC1
tetratricopeptide repeat domain 1
chr1_-_109770581 0.757 PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr11_-_14498443 0.752 PSMA1
proteasome (prosome, macropain) subunit, alpha type, 1
chr15_-_81037554 0.752 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr12_+_63132106 0.748 NM_013254
TBK1
TANK-binding kinase 1
chrX_+_41078353 0.738 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr15_+_42616665 0.735 EIF3J
eukaryotic translation initiation factor 3, subunit J
chr5_+_159368690 0.731 TTC1
tetratricopeptide repeat domain 1
chr17_-_70662364 0.728 NM_001002032
NM_001002033
NM_016185
HN1


hematological and neurological expressed 1


chr1_+_13948518 0.724 PRDM2
PR domain containing 2, with ZNF domain
chr5_-_137938938 0.723 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr4_-_38710376 0.716 NM_024943
TMEM156
transmembrane protein 156
chr8_-_59734474 0.713 NM_001144772
NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr2_-_233349469 0.708 NM_001172416
NM_001172417
NM_002242
KCNJ13


potassium inwardly-rectifying channel, subfamily J, member 13


chr15_+_38520594 0.702 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chrX_-_64671319 0.699 LAS1L
LAS1-like (S. cerevisiae)
chr10_+_91051685 0.697 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr19_-_1989937 0.695 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr15_+_42616624 0.690 EIF3J
eukaryotic translation initiation factor 3, subunit J
chr14_-_22354389 0.681 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr6_-_84197370 0.680 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr1_-_109770474 0.678 NM_002790
PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr2_-_61618165 0.677 XPO1
exportin 1 (CRM1 homolog, yeast)
chr4_-_977163 0.677 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr22_-_17846725 0.675 NM_001035247
NM_005659
UFD1L

ubiquitin fusion degradation 1 like (yeast)

chr6_-_84197477 0.673 ME1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr5_+_159368733 0.672 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr1_-_181826292 0.666 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr1_-_115682374 0.659 NM_002506
NGF
nerve growth factor (beta polypeptide)
chrX_-_72351348 0.659 NAP1L2
nucleosome assembly protein 1-like 2
chr10_-_99042419 0.652 ARHGAP19
Rho GTPase activating protein 19
chr14_-_106193403 0.650 IGKV3-20
immunoglobulin kappa variable 3-20
chr4_+_170817787 0.640 CLCN3
chloride channel 3
chr22_-_17846621 0.635 UFD1L
ubiquitin fusion degradation 1 like (yeast)
chr3_+_134601479 0.635 NM_003571
BFSP2
beaded filament structural protein 2, phakinin
chr16_+_2023279 0.634 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr10_+_35456393 0.632 NM_181571
NM_183060
CREM

cAMP responsive element modulator

chr1_-_114103616 0.616 PHTF1
putative homeodomain transcription factor 1
chr1_-_152201814 0.615 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr22_-_37598176 0.615 NM_014292
CBX6
chromobox homolog 6
chr11_-_64906683 0.612 NM_001077241
NM_182556
SLC25A45

solute carrier family 25, member 45

chr7_+_64476167 0.609 NM_007139
NM_152626
ZNF92

zinc finger protein 92

chr8_-_108579270 0.609 NM_001146
ANGPT1
angiopoietin 1
chr11_-_14498462 0.608 NM_001143937
NM_002786
PSMA1

proteasome (prosome, macropain) subunit, alpha type, 1

chr6_-_35996915 0.607 NM_003137
SRPK1
SRSF protein kinase 1
chrX_-_64671362 0.607 NM_001170649
NM_001170650
NM_031206
LAS1L


LAS1-like (S. cerevisiae)


chr11_-_47404033 0.603 PSMC3
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr14_-_22354457 0.602 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr17_-_43254117 0.600 OSBPL7
oxysterol binding protein-like 7
chr6_-_30793436 0.594 NM_014641
MDC1
mediator of DNA-damage checkpoint 1
chr11_-_3818713 0.592 RHOG
ras homolog gene family, member G (rho G)
chr6_-_31812049 0.592 CLIC1
chloride intracellular channel 1
chr8_-_59734742 0.588 NSMAF
neutral sphingomyelinase (N-SMase) activation associated factor
chr5_-_137938904 0.586 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr3_+_133855979 0.583 NM_198329
UBA5
ubiquitin-like modifier activating enzyme 5
chr2_-_219881937 0.582 PTPRN
protein tyrosine phosphatase, receptor type, N
chr2_+_86521999 0.582 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr17_-_43254132 0.581 NM_145798
OSBPL7
oxysterol binding protein-like 7
chr18_-_257987 0.581 NM_005131
THOC1
THO complex 1
chr10_-_99042381 0.578 NM_032900
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 read-through transcript
Rho GTPase activating protein 19
chr21_-_32573195 0.576 NM_018944
MIS18A
MIS18 kinetochore protein homolog A (S. pombe)
chr17_+_27701291 0.576 ZNF207
zinc finger protein 207
chr4_-_77163609 0.571 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr22_-_37858871 0.571 CBX7
chromobox homolog 7
chr7_+_148026819 0.568 NM_003592
CUL1
cullin 1
chr2_+_231629869 0.567 PSMD1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
5.89 4.09e-07 GO:0051443 positive regulation of ubiquitin-protein ligase activity
6.18 5.13e-07 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.54 6.02e-07 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
6.54 6.02e-07 GO:0072395 signal transduction involved in cell cycle checkpoint
6.54 6.02e-07 GO:0072401 signal transduction involved in DNA integrity checkpoint
6.54 6.02e-07 GO:0072404 signal transduction involved in G1/S transition checkpoint
6.54 6.02e-07 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
6.54 6.02e-07 GO:0072422 signal transduction involved in DNA damage checkpoint
6.54 6.02e-07 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
6.54 6.02e-07 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
7.01 6.46e-07 GO:0006521 regulation of cellular amino acid metabolic process
5.58 1.12e-06 GO:0051351 positive regulation of ligase activity
6.22 1.44e-06 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.22 1.44e-06 GO:0071158 positive regulation of cell cycle arrest
5.83 1.50e-06 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.93 3.27e-06 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
5.93 3.27e-06 GO:0051352 negative regulation of ligase activity
5.93 3.27e-06 GO:0051444 negative regulation of ubiquitin-protein ligase activity
5.24 3.61e-06 GO:0051438 regulation of ubiquitin-protein ligase activity
5.43 5.13e-06 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
5.29 8.13e-06 GO:2000045 regulation of G1/S transition of mitotic cell cycle
4.99 8.56e-06 GO:0051340 regulation of ligase activity
5.86 1.20e-05 GO:0033238 regulation of cellular amine metabolic process
4.65 1.24e-05 GO:0031398 positive regulation of protein ubiquitination
5.27 2.30e-05 GO:0031575 mitotic cell cycle G1/S transition checkpoint
5.27 2.30e-05 GO:0071779 G1/S transition checkpoint
5.06 4.44e-05 GO:0000216 M/G1 transition of mitotic cell cycle
4.75 1.23e-04 GO:0031397 negative regulation of protein ubiquitination
4.24 1.42e-04 GO:0000077 DNA damage checkpoint
4.57 2.18e-04 GO:0030330 DNA damage response, signal transduction by p53 class mediator
4.04 3.19e-04 GO:0031570 DNA integrity checkpoint
3.56 3.60e-04 GO:0010498 proteasomal protein catabolic process
3.56 3.60e-04 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
3.60 1.06e-03 GO:0031396 regulation of protein ubiquitination
3.90 1.15e-03 GO:0000084 S phase of mitotic cell cycle
3.90 1.15e-03 GO:0042770 signal transduction in response to DNA damage
3.83 1.54e-03 GO:0051320 S phase
1.97 2.55e-03 GO:0006508 proteolysis
3.84 3.02e-03 GO:0090068 positive regulation of cell cycle process
2.57 3.76e-03 GO:0031401 positive regulation of protein modification process
2.57 3.76e-03 GO:0051603 proteolysis involved in cellular protein catabolic process
2.61 3.92e-03 GO:0006511 ubiquitin-dependent protein catabolic process
3.59 4.07e-03 GO:0007093 mitotic cell cycle checkpoint
2.53 5.14e-03 GO:0044257 cellular protein catabolic process
2.55 6.35e-03 GO:0019941 modification-dependent protein catabolic process
2.53 7.42e-03 GO:0043632 modification-dependent macromolecule catabolic process
3.12 1.04e-02 GO:0031400 negative regulation of protein modification process
3.19 1.29e-02 GO:0000082 G1/S transition of mitotic cell cycle
2.36 2.07e-02 GO:0030163 protein catabolic process
2.22 3.71e-02 GO:0032270 positive regulation of cellular protein metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
7.57 1.21e-10 GO:0000502 proteasome complex
15.95 9.79e-04 GO:0019773 proteasome core complex, alpha-subunit complex
8.68 2.05e-03 GO:0005839 proteasome core complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
5.58 3.21e-03 GO:0003823 antigen binding
8.23 4.65e-03 GO:0004298 threonine-type endopeptidase activity
8.23 4.65e-03 GO:0070003 threonine-type peptidase activity