Motif ID: NFE2L2.p2

Z-value: 1.807


Transcription factors associated with NFE2L2.p2:

Gene SymbolEntrez IDGene Name
NFE2L2 4780 nuclear factor (erythroid-derived 2)-like 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L2chr2_-_177837540-0.837.6e-05Click!


Activity profile for motif NFE2L2.p2.

activity profile for motif NFE2L2.p2


Sorted Z-values histogram for motif NFE2L2.p2

Sorted Z-values for motif NFE2L2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_21340757 10.265


chr22_+_21116283 6.207


chrX_-_154216929 5.891 NM_001289
 CLIC2
chloride intracellular channel 2
chr22_+_21370394 5.862 IGL@
immunoglobulin lambda locus
chr22_+_21065134 5.806 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21053972 5.446


chr22_+_21065207 5.330 IGLJ3
immunoglobulin lambda joining 3
chr22_+_20899155 5.201


chr22_+_21079355 4.852


chrX_-_100527799 4.687 NM_000061
 BTK
Bruton agammaglobulinemia tyrosine kinase
chr22_+_21495273 4.613


chr22_+_21011653 4.484


chr14_-_106038573 3.794 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_106270497 3.714 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr22_+_21559959 3.689 NM_001178126
 IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr22_+_21407066 3.684


chr9_-_122728173 3.653 TRAF1
TNF receptor-associated factor 1
chr14_-_106084519 3.321 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_+_27795633 3.128 PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr17_-_25642962 3.043 NM_000386
 BLMH
bleomycin hydrolase

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 50 entries
enrichment   p-value GO term description
7.01 6.46e-07 GO:0006521 regulation of cellular amino acid metabolic process
6.54 6.02e-07 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
6.54 6.02e-07 GO:0072395 signal transduction involved in cell cycle checkpoint
6.54 6.02e-07 GO:0072401 signal transduction involved in DNA integrity checkpoint
6.54 6.02e-07 GO:0072404 signal transduction involved in G1/S transition checkpoint
6.54 6.02e-07 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
6.54 6.02e-07 GO:0072422 signal transduction involved in DNA damage checkpoint
6.54 6.02e-07 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
6.54 6.02e-07 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
6.22 1.44e-06 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
6.22 1.44e-06 GO:0071158 positive regulation of cell cycle arrest
6.18 5.13e-07 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.93 3.27e-06 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
5.93 3.27e-06 GO:0051352 negative regulation of ligase activity
5.93 3.27e-06 GO:0051444 negative regulation of ubiquitin-protein ligase activity
5.89 4.09e-07 GO:0051443 positive regulation of ubiquitin-protein ligase activity
5.86 1.20e-05 GO:0033238 regulation of cellular amine metabolic process
5.83 1.50e-06 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
5.58 1.12e-06 GO:0051351 positive regulation of ligase activity
5.43 5.13e-06 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
15.95 9.79e-04 GO:0019773 proteasome core complex, alpha-subunit complex
8.68 2.05e-03 GO:0005839 proteasome core complex
7.57 1.21e-10 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
8.23 4.65e-03 GO:0004298 threonine-type endopeptidase activity
8.23 4.65e-03 GO:0070003 threonine-type peptidase activity
5.58 3.21e-03 GO:0003823 antigen binding