Motif ID: MYFfamily.p2

Z-value: 2.831


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_176976850.332.2e-01Click!
MYF6chr12_+_796255380.185.0e-01Click!
MYF5chr12_+_796348200.175.4e-01Click!
MYOGchr1_-_201321711,
chr1_-_201321999
0.136.4e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_31997738 8.985 OSBPL10
oxysterol binding protein-like 10
chr12_-_74710741 8.415 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr4_-_57671273 8.136 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57671307 7.983 IGFBP7
insulin-like growth factor binding protein 7
chr12_-_74711474 7.557 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr4_-_57671112 6.854 IGFBP7
insulin-like growth factor binding protein 7
chr1_-_56817802 6.491 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_227372574 6.171 IRS1
insulin receptor substrate 1
chr12_-_105165805 5.726 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr12_-_74711642 5.708 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr10_+_124210980 4.982 NM_002775
HTRA1
HtrA serine peptidase 1
chr1_-_56817717 4.958 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_161058120 4.854 RBMS1
RNA binding motif, single stranded interacting protein 1
chr16_-_73198416 4.820 GLG1
golgi glycoprotein 1
chr12_-_88270128 4.673 DUSP6
dual specificity phosphatase 6
chr8_+_56177567 4.464 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr13_+_113546912 4.429 GAS6
growth arrest-specific 6
chr6_+_107917965 4.366 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chrX_-_37964924 4.219 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr13_+_113546943 4.076 GAS6
growth arrest-specific 6
chr1_-_56817568 4.050 PPAP2B
phosphatidic acid phosphatase type 2B
chr10_+_89409332 4.029 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr13_+_113546841 3.834 NM_000820
GAS6
growth arrest-specific 6
chr2_+_36436873 3.753 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr2_+_217206450 3.720 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr13_+_113546897 3.692 GAS6
growth arrest-specific 6
chr2_-_161058550 3.613 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr1_+_167342149 3.519 ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_-_160362982 3.313 NM_001198763
NM_001198764
NM_014880
CD302


CD302 molecule


chr8_+_31616809 3.272 NM_013962
NRG1
neuregulin 1
chr14_-_51605487 3.265 NID2
nidogen 2 (osteonidogen)
chr3_-_147361465 3.134 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr3_-_147361626 3.130 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr2_+_217206327 3.100 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr2_-_160362914 3.087 CD302
CD302 molecule
chr4_+_169989680 3.052 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr3_-_49370682 3.019 GPX1
glutathione peroxidase 1
chr1_-_59020875 3.016 JUN
jun proto-oncogene
chr6_-_31347867 3.010 HLA-C
major histocompatibility complex, class I, C
chr2_-_56004366 2.976 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr10_+_124211353 2.975 HTRA1
HtrA serine peptidase 1
chr6_+_114285209 2.945 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr3_-_126257425 2.882 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr11_-_11986704 2.859 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chrX_+_153767803 2.760 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr18_+_59788242 2.750 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr8_-_23768242 2.725 NM_003155
STC1
stanniocalcin 1
chrX_-_154341451 2.623 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr5_+_140844810 2.607 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr13_+_109757593 2.579 NM_001846
COL4A2
collagen, type IV, alpha 2
chr2_-_227371698 2.567 NM_005544
IRS1
insulin receptor substrate 1
chr16_-_73198498 2.537 GLG1
golgi glycoprotein 1
chr14_-_74148422 2.535 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr2_-_160972606 2.517 RBMS1
RNA binding motif, single stranded interacting protein 1
chr6_-_31347805 2.512 NM_002117
HLA-C
major histocompatibility complex, class I, C
chr16_-_73198515 2.488 NM_001145666
NM_001145667
NM_012201
GLG1


golgi glycoprotein 1


chr22_+_31527678 2.467 TIMP3
TIMP metallopeptidase inhibitor 3
chr17_-_74433048 2.433 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr9_-_83494198 2.385 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_-_20075889 2.379 MATN3
matrilin 3
chr2_+_191454036 2.336 GLS
glutaminase
chr19_+_3045266 2.334 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr5_+_92946348 2.256 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr2_+_173000552 2.241 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr17_-_74432800 2.234 TIMP2
TIMP metallopeptidase inhibitor 2
chr8_+_37773991 2.224 GPR124
G protein-coupled receptor 124
chr19_+_3045528 2.220 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr10_-_15453060 2.211 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr10_+_53744043 2.207 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr1_+_63831479 2.206 NM_002633
PGM1
phosphoglucomutase 1
chr2_-_189752575 2.180 NM_000393
COL5A2
collagen, type V, alpha 2
chr21_+_41461962 2.174 BACE2
beta-site APP-cleaving enzyme 2
chr1_+_24944346 2.169 NM_013943
CLIC4
chloride intracellular channel 4
chr12_-_47605478 2.107 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr15_+_94674849 2.103 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr8_+_37773564 2.099 GPR124
G protein-coupled receptor 124
chr8_+_37773553 2.019 NM_032777
GPR124
G protein-coupled receptor 124
chr10_+_120957084 2.003 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr15_+_97009194 1.979 IGF1R
insulin-like growth factor 1 receptor
chr2_+_191453791 1.967 NM_014905
GLS
glutaminase
chr4_-_102487356 1.964 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr18_+_54681657 1.948 ZNF532
zinc finger protein 532
chr17_-_15104768 1.944 NM_153322
PMP22
peripheral myelin protein 22
chr12_-_53099269 1.938 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr3_-_130807865 1.935 NM_015103
PLXND1
plexin D1
chr2_+_173000590 1.917 ITGA6
integrin, alpha 6
chr1_+_24944493 1.905 CLIC4
chloride intracellular channel 4
chr2_-_216009015 1.896 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr21_+_41461597 1.879 NM_012105
NM_138991
NM_138992
BACE2


beta-site APP-cleaving enzyme 2


chr19_-_18912112 1.873 NM_001145722
NM_001145721
HOMER3

homer homolog 3 (Drosophila)

chrX_-_140098941 1.869 LDOC1
leucine zipper, down-regulated in cancer 1
chr18_-_24010944 1.865 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr17_+_35853177 1.862 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chrX_-_140098959 1.857 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr12_-_6535481 1.837 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr8_+_136539290 1.836 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr5_-_178705036 1.817 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr8_+_37773915 1.813 GPR124
G protein-coupled receptor 124
chr8_-_62789665 1.798 ASPH
aspartate beta-hydroxylase
chr18_-_24011349 1.790 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr8_-_62789483 1.779 ASPH
aspartate beta-hydroxylase
chr7_+_32963486 1.774 NM_007270
FKBP9
FK506 binding protein 9, 63 kDa
chrX_-_140099014 1.758 LDOC1
leucine zipper, down-regulated in cancer 1
chrX_-_37916138 1.752 SRPX
sushi-repeat containing protein, X-linked
chr3_-_101316038 1.752 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr16_+_85101605 1.746 NM_001451
FOXF1
forkhead box F1
chr12_+_51777684 1.744 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr7_+_100037817 1.731 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr11_+_32069183 1.716 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr12_-_7153068 1.715 NM_016546
C1RL
complement component 1, r subcomponent-like
chr2_+_191453813 1.709 GLS
glutaminase
chr6_-_132314004 1.706 NM_001901
CTGF
connective tissue growth factor
chr4_-_102486975 1.687 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_-_79151232 1.687 NM_001145845
NM_133631
ROBO1

roundabout, axon guidance receptor, homolog 1 (Drosophila)

chr22_-_35011703 1.687 MYH9
myosin, heavy chain 9, non-muscle
chr22_-_35113797 1.670 MYH9
myosin, heavy chain 9, non-muscle
chr20_-_23014828 1.665 NM_012072
CD93
CD93 molecule
chr7_+_93861808 1.644 NM_000089
COL1A2
collagen, type I, alpha 2
chr13_-_109236897 1.641 NM_003749
IRS2
insulin receptor substrate 2
chr12_-_53099203 1.630 ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr21_+_45699830 1.623 NM_030582
NM_130444
COL18A1

collagen, type XVIII, alpha 1

chr19_-_54835162 1.622 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr22_+_29819343 1.601 SMTN
smoothelin
chr20_+_3399615 1.585 NM_139321
NM_139322
ATRN

attractin

chr4_-_120769275 1.566 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chr11_-_6298284 1.562 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr1_+_24944554 1.555 CLIC4
chloride intracellular channel 4
chr3_-_147361912 1.540 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr12_-_53099277 1.539 NM_002205
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr1_-_20682541 1.537


chr9_-_14304036 1.534 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr4_-_102487649 1.515 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr6_+_43151922 1.499 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr2_-_220144427 1.494 OBSL1
obscurin-like 1
chr2_-_21120420 1.480 NM_000384
APOB
apolipoprotein B (including Ag(x) antigen)
chr11_-_86343859 1.479 NM_012193
FZD4
frizzled homolog 4 (Drosophila)
chr21_-_27139143 1.467 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr12_+_51777715 1.457 IGFBP6
insulin-like growth factor binding protein 6
chr8_+_17478214 1.448 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr5_-_178704934 1.440 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr3_-_151171576 1.417 PFN2
profilin 2
chr2_+_71148915 1.414 NM_017567
NAGK
N-acetylglucosamine kinase
chr8_-_62789721 1.402 NM_001164754
NM_001164755
NM_001164756
NM_004318
NM_032466
ASPH




aspartate beta-hydroxylase




chr9_+_123070276 1.398 GSN
gelsolin
chr9_+_113433364 1.365 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr3_-_191321601 1.364 NM_018192
LEPREL1
leprecan-like 1
chr13_-_71338558 1.360 DACH1
dachshund homolog 1 (Drosophila)
chr1_+_178390660 1.356 QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr14_-_51605515 1.348 NID2
nidogen 2 (osteonidogen)
chr2_+_20510312 1.343 NM_004040
RHOB
ras homolog gene family, member B
chr22_+_31527744 1.340 TIMP3
TIMP metallopeptidase inhibitor 3
chr1_+_63832067 1.334 NM_001172819
PGM1
phosphoglucomutase 1
chr17_-_37221671 1.332 LEPREL4
leprecan-like 4
chr4_-_5071996 1.322 NM_018659
CYTL1
cytokine-like 1
chrX_-_92815222 1.321 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr14_-_93926679 1.320 NM_001002235
NM_001002236
NM_001127700
NM_001127701
NM_001127702
NM_001127703
NM_001127704
NM_001127705
NM_001127706
NM_001127707
SERPINA1









serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1









chr9_-_14303899 1.296 NFIB
nuclear factor I/B
chr14_+_64076916 1.289 NM_021979
HSPA2
heat shock 70kDa protein 2
chr1_-_98159182 1.285 NM_000110
NM_001160301
DPYD

dihydropyrimidine dehydrogenase

chr12_-_55960501 1.274 R3HDM2
R3H domain containing 2
chr3_+_128190070 1.273 NM_032242
PLXNA1
plexin A1
chr14_-_51605695 1.268 NM_007361
NID2
nidogen 2 (osteonidogen)
chr5_+_52812165 1.265 FST
follistatin
chr14_+_89933055 1.259 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr16_-_87450849 1.257 NM_000512
GALNS
galactosamine (N-acetyl)-6-sulfate sulfatase
chr7_+_93862137 1.255 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr1_-_223907283 1.250 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr13_+_34414390 1.244 NM_015678
NBEA
neurobeachin
chr14_-_74029788 1.231 NM_006432
NPC2
Niemann-Pick disease, type C2
chr16_+_55217085 1.226 NM_175617
MT1E
metallothionein 1E
chr14_-_74029720 1.223 NPC2
Niemann-Pick disease, type C2
chr15_+_72006015 1.222 LOXL1
lysyl oxidase-like 1
chrX_+_154264931 1.220 NM_001007523
NM_001007524
NM_012151
F8A2
F8A3
F8A1
coagulation factor VIII-associated (intronic transcript) 2
coagulation factor VIII-associated (intronic transcript) 3
coagulation factor VIII-associated (intronic transcript) 1
chr17_+_45488330 1.219 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr1_+_178390598 1.216 QSOX1
quiescin Q6 sulfhydryl oxidase 1
chr11_-_11987115 1.215 DKK3
dickkopf homolog 3 (Xenopus laevis)
chr11_-_65871592 1.213 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr20_+_43953428 1.213 CTSA
cathepsin A
chr1_-_154913712 1.210 NM_006617
NES
nestin
chr3_-_151171190 1.209 NM_002628
NM_053024
PFN2

profilin 2

chr14_-_74029756 1.208 NPC2
Niemann-Pick disease, type C2
chr1_+_85819004 1.206 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr15_-_46724360 1.197 FBN1
fibrillin 1
chr11_+_113671744 1.191 NM_006169
NNMT
nicotinamide N-methyltransferase
chr3_-_87122936 1.174 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr6_+_151688327 1.168 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr5_+_52812236 1.165 NM_006350
NM_013409
FST

follistatin

chr16_+_55217180 1.160 MT1E
metallothionein 1E
chr9_-_128924706 1.146 ANGPTL2
angiopoietin-like 2
chr9_-_129656830 1.145 NM_000118
NM_001114753
ENG

endoglin

chr7_-_136678815 1.144 PTN
pleiotrophin
chr9_-_129656581 1.143 ENG
endoglin
chr11_-_102174102 1.142 NM_001145938
NM_002421
MMP1

matrix metallopeptidase 1 (interstitial collagenase)

chr5_-_121440704 1.140 NM_001178102
LOX
lysyl oxidase
chr11_-_102174032 1.138 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr10_-_79067552 1.131 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr14_-_74491878 1.127 NM_002632
PGF
placental growth factor
chr1_-_98159113 1.118 DPYD
dihydropyrimidine dehydrogenase
chr1_+_51474558 1.116 RNF11
ring finger protein 11
chr19_+_50041400 1.115 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.33 2.20e-15 GO:0032502 developmental process
1.27 8.09e-15 GO:0032501 multicellular organismal process
1.35 3.94e-14 GO:0048856 anatomical structure development
1.33 1.50e-13 GO:0007275 multicellular organismal development
1.37 2.92e-13 GO:0048731 system development
1.52 3.24e-12 GO:0009653 anatomical structure morphogenesis
1.38 8.83e-09 GO:0048869 cellular developmental process
1.37 4.47e-08 GO:0030154 cell differentiation
1.41 4.72e-07 GO:0007399 nervous system development
1.58 1.23e-06 GO:0007155 cell adhesion
1.58 1.23e-06 GO:0022610 biological adhesion
1.34 3.33e-06 GO:0048513 organ development
1.93 7.27e-06 GO:0061061 muscle structure development
1.51 1.19e-05 GO:0009888 tissue development
1.51 1.38e-05 GO:0048699 generation of neurons
1.49 2.16e-05 GO:0022008 neurogenesis
1.48 2.63e-05 GO:0050793 regulation of developmental process
1.60 3.26e-05 GO:0000902 cell morphogenesis
1.48 3.38e-05 GO:0048468 cell development
1.21 3.65e-05 GO:0023052 signaling
1.66 4.91e-05 GO:0072358 cardiovascular system development
1.66 4.91e-05 GO:0072359 circulatory system development
1.57 5.59e-05 GO:0032989 cellular component morphogenesis
1.34 7.08e-05 GO:0023051 regulation of signaling
1.22 8.22e-05 GO:0007165 signal transduction
1.64 8.29e-05 GO:0000904 cell morphogenesis involved in differentiation
1.36 1.56e-04 GO:0009966 regulation of signal transduction
1.53 1.62e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.27 2.44e-04 GO:0065008 regulation of biological quality
1.52 2.55e-04 GO:0045595 regulation of cell differentiation
1.65 3.27e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.78 5.16e-04 GO:0001944 vasculature development
1.51 5.21e-04 GO:0030182 neuron differentiation
1.59 5.84e-04 GO:0048858 cell projection morphogenesis
1.25 5.88e-04 GO:0042221 response to chemical stimulus
1.85 7.01e-04 GO:0030168 platelet activation
2.49 7.53e-04 GO:0002576 platelet degranulation
1.75 7.84e-04 GO:0001501 skeletal system development
1.58 1.01e-03 GO:0032990 cell part morphogenesis
1.78 1.18e-03 GO:0001568 blood vessel development
1.28 1.22e-03 GO:0007166 cell surface receptor linked signaling pathway
1.61 1.31e-03 GO:0048812 neuron projection morphogenesis
1.28 1.57e-03 GO:0048583 regulation of response to stimulus
1.69 1.94e-03 GO:0007411 axon guidance
1.53 2.00e-03 GO:0048666 neuron development
1.13 2.12e-03 GO:0050896 response to stimulus
1.92 2.44e-03 GO:0007517 muscle organ development
1.61 2.59e-03 GO:0007409 axonogenesis
1.45 2.67e-03 GO:2000026 regulation of multicellular organismal development
1.51 2.73e-03 GO:0009887 organ morphogenesis
1.49 2.98e-03 GO:0030030 cell projection organization
1.56 3.10e-03 GO:0031175 neuron projection development
1.91 3.86e-03 GO:0006887 exocytosis
1.71 3.96e-03 GO:0051270 regulation of cellular component movement
1.72 4.23e-03 GO:0040012 regulation of locomotion
1.69 6.46e-03 GO:0032940 secretion by cell
1.73 6.94e-03 GO:0030334 regulation of cell migration
2.06 7.01e-03 GO:0060537 muscle tissue development
1.39 7.65e-03 GO:0040011 locomotion
1.52 7.94e-03 GO:0006935 chemotaxis
1.52 7.94e-03 GO:0042330 taxis
1.80 8.21e-03 GO:0048514 blood vessel morphogenesis
1.37 9.39e-03 GO:0032879 regulation of localization
1.68 9.54e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.72 9.72e-03 GO:2000145 regulation of cell motility
2.18 1.27e-02 GO:0048736 appendage development
2.18 1.27e-02 GO:0060173 limb development
1.46 1.59e-02 GO:0042060 wound healing
1.65 1.65e-02 GO:0051093 negative regulation of developmental process
1.31 1.68e-02 GO:0051239 regulation of multicellular organismal process
1.53 1.74e-02 GO:0051094 positive regulation of developmental process
1.39 2.19e-02 GO:0051128 regulation of cellular component organization
1.62 2.37e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.60 2.69e-02 GO:0048598 embryonic morphogenesis
1.33 3.10e-02 GO:0010646 regulation of cell communication
1.35 3.67e-02 GO:0009611 response to wounding
2.06 3.85e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.48 4.34e-02 GO:0001775 cell activation
3.44 4.41e-02 GO:0010464 regulation of mesenchymal cell proliferation
2.00 4.95e-02 GO:0048705 skeletal system morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 7.19e-11 GO:0016020 membrane
1.26 2.17e-10 GO:0071944 cell periphery
1.26 2.96e-10 GO:0005886 plasma membrane
1.40 6.57e-10 GO:0005576 extracellular region
1.53 2.30e-09 GO:0044421 extracellular region part
1.90 2.19e-08 GO:0031012 extracellular matrix
1.18 3.02e-08 GO:0044425 membrane part
1.31 2.94e-07 GO:0044459 plasma membrane part
1.19 1.68e-06 GO:0031224 intrinsic to membrane
1.49 9.57e-06 GO:0005615 extracellular space
1.83 1.46e-05 GO:0005578 proteinaceous extracellular matrix
1.18 2.07e-05 GO:0016021 integral to membrane
2.33 1.28e-04 GO:0005788 endoplasmic reticulum lumen
2.26 1.55e-04 GO:0044420 extracellular matrix part
2.69 6.03e-04 GO:0031983 vesicle lumen
1.50 9.91e-04 GO:0030054 cell junction
2.73 1.25e-03 GO:0031093 platelet alpha granule lumen
2.67 1.93e-03 GO:0034774 secretory granule lumen
1.57 2.64e-03 GO:0009986 cell surface
2.57 4.39e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
1.38 5.97e-03 GO:0031982 vesicle
2.41 6.27e-03 GO:0005604 basement membrane
1.36 1.54e-02 GO:0031410 cytoplasmic vesicle
2.35 1.54e-02 GO:0031091 platelet alpha granule
1.36 2.56e-02 GO:0031988 membrane-bounded vesicle
1.81 3.24e-02 GO:0005912 adherens junction
1.25 3.57e-02 GO:0031226 intrinsic to plasma membrane
1.55 4.13e-02 GO:0015629 actin cytoskeleton
1.75 4.74e-02 GO:0070161 anchoring junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.48 1.70e-06 GO:0019838 growth factor binding
1.48 6.66e-04 GO:0005509 calcium ion binding
1.62 1.88e-03 GO:0008047 enzyme activator activity
1.68 2.35e-03 GO:0032403 protein complex binding
3.79 2.39e-03 GO:0005520 insulin-like growth factor binding
2.40 2.49e-03 GO:0005201 extracellular matrix structural constituent
1.38 3.27e-03 GO:0030234 enzyme regulator activity
1.29 1.20e-02 GO:0004872 receptor activity
1.59 1.98e-02 GO:0003779 actin binding
1.44 2.40e-02 GO:0008092 cytoskeletal protein binding