Motif ID: MYFfamily.p2

Z-value: 2.831


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MYOD1chr11_+_176976850.332.2e-01Click!
MYF6chr12_+_796255380.185.0e-01Click!
MYF5chr12_+_796348200.175.4e-01Click!
MYOGchr1_-_201321711,
chr1_-_201321999		0.136.4e-01Click!


Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_31997738 8.985 OSBPL10
oxysterol binding protein-like 10
chr12_-_74710741 8.415 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr4_-_57671273 8.136 NM_001553
 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57671307 7.983 IGFBP7
insulin-like growth factor binding protein 7
chr12_-_74711474 7.557 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr4_-_57671112 6.854 IGFBP7
insulin-like growth factor binding protein 7
chr1_-_56817802 6.491 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_227372574 6.171 IRS1
insulin receptor substrate 1
chr12_-_105165805 5.726 NM_006825
 CKAP4
cytoskeleton-associated protein 4
chr12_-_74711642 5.708 NM_007350
 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr10_+_124210980 4.982 NM_002775
 HTRA1
HtrA serine peptidase 1
chr1_-_56817717 4.958 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_161058120 4.854 RBMS1
RNA binding motif, single stranded interacting protein 1
chr16_-_73198416 4.820 GLG1
golgi glycoprotein 1
chr12_-_88270128 4.673 DUSP6
dual specificity phosphatase 6
chr8_+_56177567 4.464 NM_052898
 XKR4
XK, Kell blood group complex subunit-related family, member 4
chr13_+_113546912 4.429 GAS6
growth arrest-specific 6
chr6_+_107917965 4.366 NM_018013
 SOBP
sine oculis binding protein homolog (Drosophila)
chrX_-_37964924 4.219 NM_001170750
NM_001170751
NM_001170752
NM_006307
 SRPX



sushi-repeat containing protein, X-linked



chr13_+_113546943 4.076 GAS6
growth arrest-specific 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 80 entries
enrichment   p-value GO term description
3.44 4.41e-02 GO:0010464 regulation of mesenchymal cell proliferation
2.49 7.53e-04 GO:0002576 platelet degranulation
2.18 1.27e-02 GO:0048736 appendage development
2.18 1.27e-02 GO:0060173 limb development
2.06 7.01e-03 GO:0060537 muscle tissue development
2.06 3.85e-02 GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
2.00 4.95e-02 GO:0048705 skeletal system morphogenesis
1.93 7.27e-06 GO:0061061 muscle structure development
1.92 2.44e-03 GO:0007517 muscle organ development
1.91 3.86e-03 GO:0006887 exocytosis
1.85 7.01e-04 GO:0030168 platelet activation
1.80 8.21e-03 GO:0048514 blood vessel morphogenesis
1.78 5.16e-04 GO:0001944 vasculature development
1.78 1.18e-03 GO:0001568 blood vessel development
1.75 7.84e-04 GO:0001501 skeletal system development
1.73 6.94e-03 GO:0030334 regulation of cell migration
1.72 4.23e-03 GO:0040012 regulation of locomotion
1.72 9.72e-03 GO:2000145 regulation of cell motility
1.71 3.96e-03 GO:0051270 regulation of cellular component movement
1.69 1.94e-03 GO:0007411 axon guidance

Gene overrepresentation in compartment category:

Showing 1 to 20 of 29 entries
enrichment   p-value GO term description
2.73 1.25e-03 GO:0031093 platelet alpha granule lumen
2.69 6.03e-04 GO:0031983 vesicle lumen
2.67 1.93e-03 GO:0034774 secretory granule lumen
2.57 4.39e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.41 6.27e-03 GO:0005604 basement membrane
2.35 1.54e-02 GO:0031091 platelet alpha granule
2.33 1.28e-04 GO:0005788 endoplasmic reticulum lumen
2.26 1.55e-04 GO:0044420 extracellular matrix part
1.90 2.19e-08 GO:0031012 extracellular matrix
1.83 1.46e-05 GO:0005578 proteinaceous extracellular matrix
1.81 3.24e-02 GO:0005912 adherens junction
1.75 4.74e-02 GO:0070161 anchoring junction
1.57 2.64e-03 GO:0009986 cell surface
1.55 4.13e-02 GO:0015629 actin cytoskeleton
1.53 2.30e-09 GO:0044421 extracellular region part
1.50 9.91e-04 GO:0030054 cell junction
1.49 9.57e-06 GO:0005615 extracellular space
1.40 6.57e-10 GO:0005576 extracellular region
1.38 5.97e-03 GO:0031982 vesicle
1.36 1.54e-02 GO:0031410 cytoplasmic vesicle

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.79 2.39e-03 GO:0005520 insulin-like growth factor binding
2.48 1.70e-06 GO:0019838 growth factor binding
2.40 2.49e-03 GO:0005201 extracellular matrix structural constituent
1.68 2.35e-03 GO:0032403 protein complex binding
1.62 1.88e-03 GO:0008047 enzyme activator activity
1.59 1.98e-02 GO:0003779 actin binding
1.48 6.66e-04 GO:0005509 calcium ion binding
1.44 2.40e-02 GO:0008092 cytoskeletal protein binding
1.38 3.27e-03 GO:0030234 enzyme regulator activity
1.29 1.20e-02 GO:0004872 receptor activity