Motif ID: TEAD1.p2

Z-value: 4.174


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD1chr11_+_126524270.924.6e-07Click!
TEAD3chr6_-_355726940.611.3e-02Click!
TEAD4chr12_+_29392500.391.4e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_132314004 26.304 NM_001901
CTGF
connective tissue growth factor
chr5_-_39460687 25.548 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr3_-_135575925 14.807 NM_016201
AMOTL2
angiomotin like 2
chr5_-_39460787 13.858 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_+_37660568 13.512 NM_003246
THBS1
thrombospondin 1
chr1_+_85819004 12.503 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr6_-_128883125 12.372 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr2_-_160972606 12.278 RBMS1
RNA binding motif, single stranded interacting protein 1
chr10_-_90702490 11.816 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr11_-_6298284 11.570 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr10_-_17699309 11.284 PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr5_-_39461054 11.220 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_+_61121806 10.678 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr7_+_134114701 10.306 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr2_-_189752575 10.132 NM_000393
COL5A2
collagen, type V, alpha 2
chr15_+_61122139 9.944 TPM1
tropomyosin 1 (alpha)
chr11_+_113671744 9.850 NM_006169
NNMT
nicotinamide N-methyltransferase
chr4_+_184257337 9.715 NM_024949
WWC2
WW and C2 domain containing 2
chr5_-_151046680 9.179 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr10_-_125843092 8.955 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
6.32 4.58e-02 GO:0007044 cell-substrate junction assembly
3.55 1.01e-02 GO:0014706 striated muscle tissue development
3.24 3.47e-02 GO:0060537 muscle tissue development
2.97 9.38e-03 GO:0007517 muscle organ development
2.67 4.23e-03 GO:0061061 muscle structure development
2.45 2.26e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.35 2.60e-02 GO:0007411 axon guidance
2.18 1.99e-02 GO:0048812 neuron projection morphogenesis
2.16 4.03e-02 GO:0007409 axonogenesis
2.13 1.49e-02 GO:0048858 cell projection morphogenesis
2.11 1.67e-03 GO:0032989 cellular component morphogenesis
2.11 1.88e-02 GO:0032990 cell part morphogenesis
2.10 2.52e-02 GO:0031175 neuron projection development
2.06 2.59e-02 GO:0006935 chemotaxis
2.06 2.59e-02 GO:0042330 taxis
2.05 4.89e-03 GO:0030030 cell projection organization
2.00 2.53e-02 GO:0000902 cell morphogenesis
1.99 1.44e-04 GO:0048468 cell development
1.97 3.64e-03 GO:0007155 cell adhesion
1.97 3.64e-03 GO:0022610 biological adhesion

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
14.76 1.69e-02 GO:0001527 microfibril
5.74 4.41e-02 GO:0001725 stress fiber
5.33 1.73e-04 GO:0016459 myosin complex
4.20 1.43e-02 GO:0005604 basement membrane
3.84 4.96e-04 GO:0044420 extracellular matrix part
3.31 1.24e-03 GO:0043235 receptor complex
2.74 6.98e-05 GO:0015629 actin cytoskeleton
2.31 3.82e-03 GO:0031012 extracellular matrix
2.26 3.73e-02 GO:0005578 proteinaceous extracellular matrix
1.92 1.62e-05 GO:0044421 extracellular region part
1.82 3.95e-03 GO:0005615 extracellular space
1.70 4.37e-06 GO:0005576 extracellular region
1.39 4.56e-02 GO:0044459 plasma membrane part
1.30 1.36e-02 GO:0071944 cell periphery
1.29 4.02e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
22.13 3.67e-02 GO:0004924 oncostatin-M receptor activity
6.74 1.96e-02 GO:0050840 extracellular matrix binding
4.86 2.88e-02 GO:0008307 structural constituent of muscle
3.91 1.90e-02 GO:0005201 extracellular matrix structural constituent
2.92 2.85e-02 GO:0005539 glycosaminoglycan binding
2.28 1.75e-02 GO:0003779 actin binding
1.96 3.31e-03 GO:0005509 calcium ion binding
1.17 3.43e-02 GO:0005515 protein binding