Motif ID: MTF1.p2

Z-value: 3.271


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MTF1chr1_-_38097811-0.155.7e-01Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_55217180 10.392 MT1E
metallothionein 1E
chr16_+_55217085 10.012 NM_175617
 MT1E
metallothionein 1E
chr10_+_124211353 8.856 HTRA1
HtrA serine peptidase 1
chr3_-_187025501 8.096 NM_001007225
NM_006548
 IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr16_+_55199978 7.960 NM_005953
 MT2A
metallothionein 2A
chr16_+_55273879 7.407 NM_005952
 MT1X
metallothionein 1X
chr16_+_55261226 7.287 NM_005951
 MT1H
metallothionein 1H
chr16_+_55249355 6.477 NM_005949
 MT1F
metallothionein 1F
chr3_-_187025438 6.243 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr10_+_124210980 6.038 NM_002775
 HTRA1
HtrA serine peptidase 1
chr9_+_132309914 5.876 NM_000050
NM_054012
 ASS1

argininosuccinate synthase 1

chr16_+_55230078 5.543 NM_005946
 MT1A
metallothionein 1A
chr2_-_224612177 5.456 NM_001136528
NM_006216
 SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr1_-_93199586 5.066 NM_001006605
 FAM69A
family with sequence similarity 69, member A
chr1_-_9806611 4.595 CLSTN1
calsyntenin 1
chr16_-_55259405 4.447 NM_005950
 MT1G
metallothionein 1G
chr16_-_51138306 4.198 NM_001080430
 TOX3
TOX high mobility group box family member 3
chr12_+_6179736 3.999 NM_001769
 CD9
CD9 molecule
chr20_-_10602139 3.983 JAG1
jagged 1
chr9_+_132310068 3.909 ASS1
argininosuccinate synthase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 108 entries
enrichment   p-value GO term description
3.03 1.82e-02 GO:0090263 positive regulation of canonical Wnt receptor signaling pathway
2.84 2.74e-03 GO:0030177 positive regulation of Wnt receptor signaling pathway
2.41 1.19e-03 GO:0050770 regulation of axonogenesis
2.27 8.60e-04 GO:0007160 cell-matrix adhesion
2.25 5.60e-06 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.23 8.43e-06 GO:0022604 regulation of cell morphogenesis
2.21 3.60e-04 GO:0031589 cell-substrate adhesion
2.19 2.40e-02 GO:0048638 regulation of developmental growth
2.13 3.36e-02 GO:0060828 regulation of canonical Wnt receptor signaling pathway
2.12 1.32e-04 GO:0030111 regulation of Wnt receptor signaling pathway
2.06 5.69e-04 GO:0010975 regulation of neuron projection development
2.02 1.53e-02 GO:0035023 regulation of Rho protein signal transduction
1.97 7.42e-04 GO:0034330 cell junction organization
1.96 3.93e-02 GO:0010720 positive regulation of cell development
1.87 8.79e-07 GO:0051960 regulation of nervous system development
1.87 9.75e-06 GO:0050767 regulation of neurogenesis
1.87 2.81e-04 GO:0045664 regulation of neuron differentiation
1.87 2.63e-02 GO:0034329 cell junction assembly
1.86 8.12e-03 GO:0031344 regulation of cell projection organization
1.85 1.77e-07 GO:0060284 regulation of cell development

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
2.66 8.35e-03 GO:0042641 actomyosin
2.19 1.81e-02 GO:0032580 Golgi cisterna membrane
1.92 1.07e-02 GO:0019898 extrinsic to membrane
1.87 1.81e-04 GO:0070161 anchoring junction
1.87 7.64e-04 GO:0005912 adherens junction
1.76 1.56e-03 GO:0031252 cell leading edge
1.59 1.15e-03 GO:0015629 actin cytoskeleton
1.41 4.58e-03 GO:0030054 cell junction
1.39 3.97e-02 GO:0000139 Golgi membrane
1.27 3.37e-02 GO:0005794 Golgi apparatus
1.25 3.93e-03 GO:0005856 cytoskeleton
1.21 4.86e-04 GO:0044459 plasma membrane part
1.19 4.09e-07 GO:0071944 cell periphery
1.19 1.06e-06 GO:0005886 plasma membrane
1.14 4.14e-09 GO:0016020 membrane
1.10 1.51e-02 GO:0044425 membrane part
1.09 3.64e-05 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
2.37 3.45e-02 GO:0046332 SMAD binding
1.99 3.15e-02 GO:0019199 transmembrane receptor protein kinase activity
1.54 1.42e-05 GO:0008092 cytoskeletal protein binding
1.53 1.04e-02 GO:0003779 actin binding
1.11 8.21e-06 GO:0005515 protein binding